LeishMANIAdb
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Putative 60S acidic ribosomal protein P2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative 60S acidic ribosomal protein P2
Gene product:
60S acidic ribosomal protein P2, putative
Species:
Leishmania mexicana
UniProt:
E9B1E6_LEIMU
TriTrypDb:
LmxM.29.3720
Length:
124

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 25
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0015934 large ribosomal subunit 4 12
GO:0022625 cytosolic large ribosomal subunit 5 12
GO:0032991 protein-containing complex 1 12
GO:0044391 ribosomal subunit 3 12
GO:1990904 ribonucleoprotein complex 2 12

Expansion

Sequence features

E9B1E6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1E6

PDB structure(s): 1s4h_A

Function

Biological processes
Term Name Level Count
GO:0002182 cytoplasmic translational elongation 6 12
GO:0006414 translational elongation 5 12
GO:0008152 metabolic process 1 12
GO:0009058 biosynthetic process 2 12
GO:0009059 macromolecule biosynthetic process 4 12
GO:0009987 cellular process 1 12
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044249 cellular biosynthetic process 3 12
GO:0044260 obsolete cellular macromolecule metabolic process 3 12
GO:0071704 organic substance metabolic process 2 12
GO:1901576 organic substance biosynthetic process 3 12
Molecular functions
Term Name Level Count
GO:0003735 structural constituent of ribosome 2 12
GO:0005198 structural molecule activity 1 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 55 59 PF00656 0.534
DEG_Nend_Nbox_1 1 3 PF02207 0.380
DOC_USP7_MATH_1 90 94 PF00917 0.506
DOC_USP7_UBL2_3 34 38 PF12436 0.365
DOC_WW_Pin1_4 32 37 PF00397 0.473
LIG_14-3-3_CanoR_1 14 22 PF00244 0.326
LIG_FHA_1 76 82 PF00498 0.507
LIG_FHA_2 103 109 PF00498 0.373
LIG_LIR_Gen_1 58 69 PF02991 0.487
LIG_LIR_Nem_3 117 123 PF02991 0.469
LIG_LIR_Nem_3 58 64 PF02991 0.474
LIG_SH2_CRK 26 30 PF00017 0.432
LIG_SH2_NCK_1 26 30 PF00017 0.432
LIG_SH2_STAP1 26 30 PF00017 0.514
LIG_SH2_STAT5 22 25 PF00017 0.406
LIG_SUMO_SIM_par_1 27 32 PF11976 0.451
LIG_TRAF2_1 110 113 PF00917 0.476
MOD_CDK_SPxK_1 32 38 PF00069 0.472
MOD_CK1_1 32 38 PF00069 0.450
MOD_CK2_1 102 108 PF00069 0.400
MOD_CK2_1 13 19 PF00069 0.364
MOD_GlcNHglycan 2 5 PF01048 0.365
MOD_GlcNHglycan 31 34 PF01048 0.465
MOD_GlcNHglycan 84 87 PF01048 0.309
MOD_GSK3_1 2 9 PF00069 0.362
MOD_GSK3_1 71 78 PF00069 0.577
MOD_NEK2_1 13 18 PF00069 0.369
MOD_PIKK_1 13 19 PF00454 0.364
MOD_PKA_2 13 19 PF00069 0.364
MOD_Plk_1 52 58 PF00069 0.476
MOD_ProDKin_1 32 38 PF00069 0.472
MOD_SUMO_rev_2 63 69 PF00179 0.478
TRG_ENDOCYTIC_2 26 29 PF00928 0.431

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HZR2 Leptomonas seymouri 68% 100%
A0A1X0P2R9 Trypanosomatidae 62% 100%
A0A3Q8ICC2 Leishmania donovani 51% 100%
A0A3Q8IG52 Leishmania donovani 86% 100%
A0A422NR90 Trypanosoma rangeli 47% 100%
A4H884 Leishmania braziliensis 49% 100%
A4I5Z9 Leishmania infantum 85% 100%
A4I600 Leishmania infantum 86% 100%
C9ZRI4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 59% 100%
E9AGM1 Leishmania infantum 51% 100%
E9AQB1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 44% 100%
E9B1E7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
O01504 Caenorhabditis elegans 45% 100%
O01725 Branchiostoma floridae 42% 100%
O14317 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 45% 100%
O24415 Zea mays 35% 100%
O43940 Leishmania donovani 85% 100%
O44010 Leishmania braziliensis 81% 100%
O61463 Cryptochiton stelleri 40% 100%
P02399 Artemia salina 45% 100%
P02400 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 45% 100%
P05319 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 41% 100%
P08094 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 42% 100%
P17478 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 39% 100%
P22683 Dictyostelium discoideum 47% 100%
P23632 Trypanosoma cruzi 62% 100%
P42037 Alternaria alternata 47% 100%
P42899 Bos taurus 38% 100%
P46252 Zea mays 38% 100%
P51407 Arabidopsis thaliana 37% 100%
P51408 Trypanosoma brucei brucei 59% 100%
P90703 Brugia malayi 39% 100%
Q06382 Leishmania infantum 48% 100%
Q06383 Leishmania infantum 73% 100%
Q29315 Sus scrofa 37% 100%
Q4Q6R5 Leishmania major 73% 100%
Q4Q6R6 Leishmania major 73% 100%
Q4QF62 Leishmania major 43% 100%
Q8TFM9 Fusarium culmorum 48% 100%
Q96UQ7 Rhodotorula glutinis 48% 100%
Q9C3Z5 Podospora anserina 53% 100%
Q9HFQ4 Candida albicans 45% 100%
Q9HFQ5 Candida albicans 46% 100%
Q9LH85 Arabidopsis thaliana 35% 100%
Q9LXM8 Arabidopsis thaliana 36% 100%
Q9UUZ6 Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) 46% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS