SnoaL-like domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B1E1_LEIMU

TriTrypDb:

LmxM.29.3670

Length:

144

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1E1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1E1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	41	45	PF00656	0.487
CLV_PCSK_SKI1_1	113	117	PF00082	0.394
CLV_PCSK_SKI1_1	134	138	PF00082	0.373
DEG_SCF_TRCP1_1	83	89	PF00400	0.474
DOC_MAPK_gen_1	121	130	PF00069	0.372
DOC_MAPK_gen_1	131	140	PF00069	0.348
DOC_MAPK_HePTP_8	128	140	PF00069	0.383
DOC_MAPK_MEF2A_6	131	140	PF00069	0.391
DOC_PP1_RVXF_1	53	60	PF00149	0.506
DOC_USP7_UBL2_3	121	125	PF12436	0.377
LIG_BIR_II_1	1	5	PF00653	0.334
LIG_BRCT_BRCA1_1	77	81	PF00533	0.389
LIG_BRCT_BRCA1_1	88	92	PF00533	0.469
LIG_FHA_1	10	16	PF00498	0.427
LIG_FHA_1	125	131	PF00498	0.368
LIG_FHA_2	137	143	PF00498	0.399
LIG_LIR_Gen_1	21	32	PF02991	0.455
LIG_LIR_Nem_3	21	27	PF02991	0.420
LIG_LIR_Nem_3	35	39	PF02991	0.403
LIG_PDZ_Class_3	139	144	PF00595	0.396
LIG_Pex14_2	59	63	PF04695	0.510
LIG_SH2_STAP1	11	15	PF00017	0.391
LIG_SH2_STAT3	97	100	PF00017	0.377
LIG_SH2_STAT5	11	14	PF00017	0.435
LIG_SH2_STAT5	26	29	PF00017	0.344
LIG_SH2_STAT5	33	36	PF00017	0.347
LIG_SUMO_SIM_par_1	126	132	PF11976	0.443
LIG_SUMO_SIM_par_1	134	139	PF11976	0.431
LIG_UBA3_1	110	116	PF00899	0.352
LIG_WRC_WIRS_1	102	107	PF05994	0.317
LIG_WRC_WIRS_1	46	51	PF05994	0.442
MOD_CK2_1	136	142	PF00069	0.353
MOD_GlcNHglycan	16	19	PF01048	0.494
MOD_GlcNHglycan	82	86	PF01048	0.631
MOD_GSK3_1	115	122	PF00069	0.510
MOD_NEK2_1	1	6	PF00069	0.441
MOD_NEK2_1	119	124	PF00069	0.477
MOD_NEK2_1	14	19	PF00069	0.255
MOD_NEK2_1	57	62	PF00069	0.487
MOD_NEK2_1	81	86	PF00069	0.643
MOD_PIKK_1	1	7	PF00454	0.315
MOD_PKA_2	9	15	PF00069	0.449
MOD_Plk_4	124	130	PF00069	0.377
MOD_Plk_4	136	142	PF00069	0.409
MOD_Plk_4	32	38	PF00069	0.386
MOD_Plk_4	45	51	PF00069	0.450
MOD_SUMO_rev_2	126	136	PF00179	0.394
TRG_ENDOCYTIC_2	102	105	PF00928	0.318
TRG_ENDOCYTIC_2	11	14	PF00928	0.435
TRG_NES_CRM1_1	108	120	PF08389	0.354

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P330	Leptomonas seymouri	69%	100%
A0A1X0P161	Trypanosomatidae	54%	92%
A0A3Q8IF89	Leishmania donovani	89%	100%
A0A422NMI2	Trypanosoma rangeli	47%	100%
A4HIV3	Leishmania braziliensis	81%	100%
A4I658	Leishmania infantum	89%	100%
C9ZRH8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	95%
Q4Q6S1	Leishmania major	88%	100%