Rhodanese domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

thiosulfate sulfurtransferase, mitochondrial, putative

Species:

Leishmania mexicana

UniProt:

E9B1C7_LEIMU

TriTrypDb:

LmxM.29.3530

Length:

247

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1C7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1C7

PDB structure(s): 7ane_au

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0004792	thiosulfate sulfurtransferase activity	5	2
GO:0016740	transferase activity	2	2
GO:0016782	transferase activity, transferring sulphur-containing groups	3	2
GO:0016783	sulfurtransferase activity	4	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	12	14	PF00675	0.551
CLV_NRD_NRD_1	151	153	PF00675	0.281
CLV_NRD_NRD_1	202	204	PF00675	0.534
CLV_PCSK_KEX2_1	12	14	PF00082	0.569
CLV_PCSK_KEX2_1	202	204	PF00082	0.534
CLV_PCSK_PC1ET2_1	202	204	PF00082	0.534
CLV_PCSK_SKI1_1	127	131	PF00082	0.354
CLV_PCSK_SKI1_1	193	197	PF00082	0.592
CLV_PCSK_SKI1_1	203	207	PF00082	0.523
CLV_PCSK_SKI1_1	5	9	PF00082	0.656
DEG_Nend_UBRbox_1	1	4	PF02207	0.606
DEG_SCF_FBW7_1	228	234	PF00400	0.469
DOC_CKS1_1	228	233	PF01111	0.470
DOC_CYCLIN_RxL_1	2	11	PF00134	0.643
DOC_MAPK_gen_1	12	20	PF00069	0.526
DOC_MAPK_gen_1	127	137	PF00069	0.473
DOC_PP1_RVXF_1	3	9	PF00149	0.532
DOC_PP4_FxxP_1	125	128	PF00568	0.437
DOC_PP4_FxxP_1	221	224	PF00568	0.550
DOC_USP7_MATH_1	191	195	PF00917	0.690
DOC_USP7_MATH_1	231	235	PF00917	0.715
DOC_WW_Pin1_4	227	232	PF00397	0.465
DOC_WW_Pin1_4	86	91	PF00397	0.472
LIG_14-3-3_CanoR_1	232	238	PF00244	0.665
LIG_AP2alpha_2	184	186	PF02296	0.678
LIG_CSL_BTD_1	101	104	PF09270	0.480
LIG_deltaCOP1_diTrp_1	28	32	PF00928	0.522
LIG_FHA_1	164	170	PF00498	0.437
LIG_FHA_1	79	85	PF00498	0.297
LIG_FHA_2	113	119	PF00498	0.462
LIG_LIR_Apic_2	184	189	PF02991	0.578
LIG_LIR_Apic_2	220	224	PF02991	0.547
LIG_LIR_Apic_2	74	79	PF02991	0.645
LIG_LIR_Gen_1	117	126	PF02991	0.449
LIG_LIR_Gen_1	172	179	PF02991	0.527
LIG_LIR_Nem_3	172	177	PF02991	0.563
LIG_MYND_3	223	227	PF01753	0.565
LIG_Pex14_1	151	155	PF04695	0.437
LIG_Pex14_1	186	190	PF04695	0.514
LIG_Pex14_2	196	200	PF04695	0.517
LIG_PTB_Apo_2	113	120	PF02174	0.491
LIG_SH2_SRC	156	159	PF00017	0.462
LIG_SH2_STAP1	110	114	PF00017	0.437
LIG_SH2_STAT3	110	113	PF00017	0.437
LIG_SH2_STAT3	216	219	PF00017	0.536
LIG_SH2_STAT3	244	247	PF00017	0.569
LIG_SH2_STAT5	41	44	PF00017	0.524
LIG_SH2_STAT5	66	69	PF00017	0.532
LIG_SUMO_SIM_anti_2	131	138	PF11976	0.438
LIG_SUMO_SIM_par_1	131	138	PF11976	0.438
MOD_CDC14_SPxK_1	89	92	PF00782	0.462
MOD_CDK_SPK_2	227	232	PF00069	0.465
MOD_CDK_SPxK_1	86	92	PF00069	0.472
MOD_CK2_1	112	118	PF00069	0.437
MOD_CMANNOS	29	32	PF00535	0.520
MOD_GSK3_1	227	234	PF00069	0.468
MOD_GSK3_1	7	14	PF00069	0.647
MOD_NEK2_1	206	211	PF00069	0.529
MOD_NEK2_2	191	196	PF00069	0.665
MOD_PKA_2	11	17	PF00069	0.541
MOD_PKA_2	231	237	PF00069	0.668
MOD_Plk_4	191	197	PF00069	0.667
MOD_Plk_4	92	98	PF00069	0.464
MOD_ProDKin_1	227	233	PF00069	0.468
MOD_ProDKin_1	86	92	PF00069	0.472
TRG_DiLeu_BaEn_2	120	126	PF01217	0.405
TRG_DiLeu_BaEn_2	77	83	PF01217	0.400
TRG_DiLeu_BaLyEn_6	2	7	PF01217	0.654
TRG_ENDOCYTIC_2	123	126	PF00928	0.405
TRG_ENDOCYTIC_2	156	159	PF00928	0.462
TRG_ENDOCYTIC_2	174	177	PF00928	0.531
TRG_ENDOCYTIC_2	57	60	PF00928	0.529
TRG_ER_diArg_1	12	15	PF00400	0.563
TRG_NLS_MonoExtN_4	199	206	PF00514	0.533
TRG_Pf-PMV_PEXEL_1	46	50	PF00026	0.480
TRG_Pf-PMV_PEXEL_1	5	9	PF00026	0.649

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2P8	Leptomonas seymouri	88%	100%
A0A0S4JLQ7	Bodo saltans	74%	100%
A0A1X0P2T4	Trypanosomatidae	81%	100%
A0A3R7NHJ2	Trypanosoma rangeli	79%	100%
A0A3S7X422	Leishmania donovani	97%	100%
A4HIT9	Leishmania braziliensis	95%	100%
A4I644	Leishmania infantum	97%	100%
C9ZRG5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	78%	100%
Q4Q6T5	Leishmania major	97%	100%
V5BMP6	Trypanosoma cruzi	79%	100%