Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B1B5_LEIMU

TriTrypDb:

LmxM.29.3400

Length:

234

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1B5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1B5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	193	195	PF00675	0.382
CLV_NRD_NRD_1	59	61	PF00675	0.375
CLV_PCSK_KEX2_1	193	195	PF00082	0.382
CLV_PCSK_KEX2_1	59	61	PF00082	0.351
CLV_PCSK_PC7_1	189	195	PF00082	0.370
CLV_PCSK_SKI1_1	110	114	PF00082	0.452
CLV_PCSK_SKI1_1	59	63	PF00082	0.405
CLV_Separin_Metazoa	56	60	PF03568	0.383
DEG_Nend_UBRbox_1	1	4	PF02207	0.384
DEG_SPOP_SBC_1	230	234	PF00917	0.427
DOC_CKS1_1	88	93	PF01111	0.445
DOC_CYCLIN_RxL_1	105	114	PF00134	0.373
DOC_CYCLIN_yCln2_LP_2	62	68	PF00134	0.445
DOC_MAPK_gen_1	105	113	PF00069	0.373
DOC_MAPK_gen_1	59	68	PF00069	0.469
DOC_MAPK_MEF2A_6	105	113	PF00069	0.377
DOC_PP1_RVXF_1	158	164	PF00149	0.415
DOC_PP4_FxxP_1	68	71	PF00568	0.410
DOC_USP7_MATH_1	154	158	PF00917	0.510
DOC_USP7_MATH_1	168	172	PF00917	0.295
DOC_USP7_MATH_1	20	24	PF00917	0.335
DOC_USP7_MATH_1	219	223	PF00917	0.273
DOC_WW_Pin1_4	16	21	PF00397	0.410
DOC_WW_Pin1_4	31	36	PF00397	0.332
DOC_WW_Pin1_4	87	92	PF00397	0.449
LIG_14-3-3_CanoR_1	25	29	PF00244	0.452
LIG_Actin_WH2_2	175	191	PF00022	0.389
LIG_APCC_ABBA_1	1	6	PF00400	0.432
LIG_APCC_ABBA_1	51	56	PF00400	0.328
LIG_FHA_1	153	159	PF00498	0.583
LIG_FHA_1	16	22	PF00498	0.457
LIG_LIR_Apic_2	31	35	PF02991	0.406
LIG_LIR_Gen_1	49	58	PF02991	0.328
LIG_LIR_Gen_1	6	16	PF02991	0.371
LIG_LIR_Nem_3	225	230	PF02991	0.457
LIG_LIR_Nem_3	49	54	PF02991	0.338
LIG_LIR_Nem_3	6	12	PF02991	0.364
LIG_MAD2	133	141	PF02301	0.475
LIG_NRBOX	57	63	PF00104	0.345
LIG_PTB_Apo_2	173	180	PF02174	0.408
LIG_SH2_CRK	100	104	PF00017	0.451
LIG_SH2_NCK_1	100	104	PF00017	0.451
LIG_SH2_NCK_1	32	36	PF00017	0.398
LIG_SH2_SRC	45	48	PF00017	0.404
LIG_SH2_STAT5	197	200	PF00017	0.342
LIG_SH2_STAT5	45	48	PF00017	0.469
LIG_SH2_STAT5	89	92	PF00017	0.584
LIG_SH3_3	135	141	PF00018	0.459
LIG_SH3_3	177	183	PF00018	0.480
LIG_TRAF2_1	8	11	PF00917	0.387
LIG_UBA3_1	106	110	PF00899	0.344
LIG_WRC_WIRS_1	21	26	PF05994	0.412
LIG_WW_3	102	106	PF00397	0.425
MOD_CK1_1	145	151	PF00069	0.716
MOD_CK1_1	23	29	PF00069	0.343
MOD_CK2_1	159	165	PF00069	0.486
MOD_CK2_1	219	225	PF00069	0.287
MOD_CK2_1	41	47	PF00069	0.365
MOD_GSK3_1	140	147	PF00069	0.574
MOD_GSK3_1	148	155	PF00069	0.559
MOD_GSK3_1	16	23	PF00069	0.455
MOD_GSK3_1	24	31	PF00069	0.397
MOD_GSK3_1	83	90	PF00069	0.515
MOD_N-GLC_1	145	150	PF02516	0.594
MOD_N-GLC_1	16	21	PF02516	0.410
MOD_NEK2_1	111	116	PF00069	0.409
MOD_NEK2_1	229	234	PF00069	0.561
MOD_NEK2_1	24	29	PF00069	0.405
MOD_NEK2_1	41	46	PF00069	0.344
MOD_NEK2_1	83	88	PF00069	0.738
MOD_NEK2_2	20	25	PF00069	0.405
MOD_PIKK_1	149	155	PF00454	0.489
MOD_PKA_2	217	223	PF00069	0.499
MOD_PKA_2	24	30	PF00069	0.450
MOD_Plk_4	41	47	PF00069	0.401
MOD_Plk_4	83	89	PF00069	0.625
MOD_ProDKin_1	16	22	PF00069	0.413
MOD_ProDKin_1	31	37	PF00069	0.330
MOD_ProDKin_1	87	93	PF00069	0.447
TRG_DiLeu_BaEn_1	225	230	PF01217	0.457
TRG_DiLeu_BaLyEn_6	102	107	PF01217	0.409
TRG_DiLeu_BaLyEn_6	124	129	PF01217	0.544
TRG_DiLeu_BaLyEn_6	57	62	PF01217	0.342
TRG_ENDOCYTIC_2	9	12	PF00928	0.406
TRG_ENDOCYTIC_2	99	102	PF00928	0.550
TRG_ER_diArg_1	58	60	PF00400	0.359
TRG_Pf-PMV_PEXEL_1	59	64	PF00026	0.314

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2I1	Leptomonas seymouri	57%	100%
A0A3Q8IJQ2	Leishmania donovani	90%	100%
A4HIS8	Leishmania braziliensis	73%	100%
A4I630	Leishmania infantum	91%	100%
Q4Q6U9	Leishmania major	89%	100%