BAR domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B1A7_LEIMU

TriTrypDb:

LmxM.29.3320

Length:

358

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B1A7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B1A7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	343	347	PF00656	0.832
CLV_NRD_NRD_1	133	135	PF00675	0.444
CLV_NRD_NRD_1	9	11	PF00675	0.549
CLV_PCSK_KEX2_1	133	135	PF00082	0.444
CLV_PCSK_KEX2_1	9	11	PF00082	0.549
CLV_PCSK_SKI1_1	106	110	PF00082	0.532
CLV_PCSK_SKI1_1	156	160	PF00082	0.515
CLV_PCSK_SKI1_1	199	203	PF00082	0.481
CLV_Separin_Metazoa	114	118	PF03568	0.489
DEG_APCC_DBOX_1	198	206	PF00400	0.489
DEG_COP1_1	255	265	PF00400	0.516
DEG_COP1_1	71	79	PF00400	0.547
DEG_Nend_UBRbox_2	1	3	PF02207	0.646
DEG_SCF_FBW7_1	284	290	PF00400	0.512
DOC_CDC14_PxL_1	73	81	PF14671	0.546
DOC_CKS1_1	232	237	PF01111	0.526
DOC_CKS1_1	248	253	PF01111	0.556
DOC_CKS1_1	284	289	PF01111	0.519
DOC_CKS1_1	310	315	PF01111	0.664
DOC_USP7_MATH_1	184	188	PF00917	0.495
DOC_USP7_MATH_1	246	250	PF00917	0.549
DOC_USP7_MATH_1	282	286	PF00917	0.758
DOC_USP7_MATH_1	305	309	PF00917	0.555
DOC_USP7_MATH_1	326	330	PF00917	0.770
DOC_USP7_MATH_1	80	84	PF00917	0.531
DOC_WW_Pin1_4	150	155	PF00397	0.566
DOC_WW_Pin1_4	22	27	PF00397	0.710
DOC_WW_Pin1_4	231	236	PF00397	0.531
DOC_WW_Pin1_4	247	252	PF00397	0.553
DOC_WW_Pin1_4	268	273	PF00397	0.706
DOC_WW_Pin1_4	283	288	PF00397	0.621
DOC_WW_Pin1_4	309	314	PF00397	0.778
DOC_WW_Pin1_4	320	325	PF00397	0.651
LIG_14-3-3_CanoR_1	177	185	PF00244	0.485
LIG_14-3-3_CanoR_1	199	208	PF00244	0.443
LIG_14-3-3_CanoR_1	30	38	PF00244	0.625
LIG_14-3-3_CanoR_1	39	47	PF00244	0.306
LIG_14-3-3_CanoR_1	9	18	PF00244	0.566
LIG_BRCT_BRCA1_1	186	190	PF00533	0.589
LIG_BRCT_BRCA1_1	215	219	PF00533	0.491
LIG_CtBP_PxDLS_1	26	30	PF00389	0.675
LIG_deltaCOP1_diTrp_1	169	176	PF00928	0.507
LIG_eIF4E_1	283	289	PF01652	0.609
LIG_EVH1_1	242	246	PF00568	0.706
LIG_FHA_1	10	16	PF00498	0.562
LIG_FHA_1	202	208	PF00498	0.483
LIG_FHA_1	232	238	PF00498	0.517
LIG_FHA_1	262	268	PF00498	0.698
LIG_FHA_1	279	285	PF00498	0.579
LIG_FHA_2	341	347	PF00498	0.754
LIG_FHA_2	63	69	PF00498	0.455
LIG_FHA_2	98	104	PF00498	0.509
LIG_LIR_Apic_2	349	355	PF02991	0.697
LIG_LIR_Gen_1	110	120	PF02991	0.489
LIG_LIR_Gen_1	139	147	PF02991	0.490
LIG_LIR_Gen_1	157	162	PF02991	0.553
LIG_LIR_Gen_1	210	219	PF02991	0.490
LIG_LIR_Nem_3	110	116	PF02991	0.497
LIG_LIR_Nem_3	139	143	PF02991	0.481
LIG_LIR_Nem_3	157	161	PF02991	0.555
LIG_LIR_Nem_3	210	214	PF02991	0.490
LIG_LIR_Nem_3	220	226	PF02991	0.537
LIG_LIR_Nem_3	312	317	PF02991	0.515
LIG_LIR_Nem_3	71	76	PF02991	0.511
LIG_MYND_1	235	239	PF01753	0.597
LIG_Pex14_2	219	223	PF04695	0.512
LIG_REV1ctd_RIR_1	140	150	PF16727	0.499
LIG_SH2_CRK	254	258	PF00017	0.480
LIG_SH2_CRK	314	318	PF00017	0.505
LIG_SH2_CRK	334	338	PF00017	0.699
LIG_SH2_CRK	352	356	PF00017	0.707
LIG_SH2_CRK	73	77	PF00017	0.514
LIG_SH2_NCK_1	254	258	PF00017	0.480
LIG_SH2_SRC	252	255	PF00017	0.774
LIG_SH2_SRC	334	337	PF00017	0.707
LIG_SH2_SRC	352	355	PF00017	0.705
LIG_SH2_STAP1	252	256	PF00017	0.483
LIG_SH2_STAT5	283	286	PF00017	0.509
LIG_SH3_1	74	80	PF00018	0.548
LIG_SH3_3	223	229	PF00018	0.553
LIG_SH3_3	232	238	PF00018	0.590
LIG_SH3_3	240	246	PF00018	0.604
LIG_SH3_3	257	263	PF00018	0.642
LIG_SH3_3	266	272	PF00018	0.632
LIG_SH3_3	281	287	PF00018	0.725
LIG_SH3_3	291	297	PF00018	0.658
LIG_SH3_3	74	80	PF00018	0.548
LIG_TRAF2_1	100	103	PF00917	0.515
LIG_TRAF2_1	25	28	PF00917	0.573
LIG_TYR_ITSM	310	317	PF00017	0.502
LIG_WRC_WIRS_1	116	121	PF05994	0.580
LIG_WRC_WIRS_1	208	213	PF05994	0.491
MOD_CDC14_SPxK_1	153	156	PF00782	0.599
MOD_CDK_SPxK_1	150	156	PF00069	0.577
MOD_CK1_1	149	155	PF00069	0.350
MOD_CK1_1	200	206	PF00069	0.482
MOD_CK1_1	255	261	PF00069	0.777
MOD_CK2_1	11	17	PF00069	0.566
MOD_CK2_1	207	213	PF00069	0.486
MOD_CK2_1	22	28	PF00069	0.598
MOD_CK2_1	62	68	PF00069	0.423
MOD_CK2_1	97	103	PF00069	0.505
MOD_GlcNHglycan	191	194	PF01048	0.585
MOD_GlcNHglycan	254	257	PF01048	0.683
MOD_GlcNHglycan	290	293	PF01048	0.638
MOD_GlcNHglycan	307	310	PF01048	0.481
MOD_GlcNHglycan	328	331	PF01048	0.630
MOD_GSK3_1	142	149	PF00069	0.345
MOD_GSK3_1	197	204	PF00069	0.480
MOD_GSK3_1	213	220	PF00069	0.498
MOD_GSK3_1	227	234	PF00069	0.572
MOD_GSK3_1	278	285	PF00069	0.798
MOD_GSK3_1	305	312	PF00069	0.625
MOD_GSK3_1	316	323	PF00069	0.762
MOD_GSK3_1	342	349	PF00069	0.755
MOD_N-GLC_1	346	351	PF02516	0.715
MOD_NEK2_1	115	120	PF00069	0.578
MOD_NEK2_1	142	147	PF00069	0.597
MOD_NEK2_1	189	194	PF00069	0.581
MOD_NEK2_1	219	224	PF00069	0.522
MOD_NEK2_1	288	293	PF00069	0.515
MOD_NEK2_1	62	67	PF00069	0.449
MOD_NEK2_1	97	102	PF00069	0.478
MOD_PIKK_1	217	223	PF00454	0.508
MOD_PIKK_1	9	15	PF00454	0.555
MOD_PIKK_1	98	104	PF00454	0.509
MOD_PKA_1	9	15	PF00069	0.555
MOD_PKA_2	176	182	PF00069	0.489
MOD_PKA_2	29	35	PF00069	0.641
MOD_PKA_2	38	44	PF00069	0.507
MOD_PKA_2	8	14	PF00069	0.553
MOD_Plk_1	156	162	PF00069	0.562
MOD_Plk_1	197	203	PF00069	0.483
MOD_Plk_4	207	213	PF00069	0.486
MOD_ProDKin_1	150	156	PF00069	0.577
MOD_ProDKin_1	22	28	PF00069	0.700
MOD_ProDKin_1	231	237	PF00069	0.532
MOD_ProDKin_1	247	253	PF00069	0.557
MOD_ProDKin_1	268	274	PF00069	0.707
MOD_ProDKin_1	283	289	PF00069	0.622
MOD_ProDKin_1	309	315	PF00069	0.779
MOD_ProDKin_1	320	326	PF00069	0.653
MOD_SUMO_for_1	43	46	PF00179	0.329
MOD_SUMO_rev_2	68	76	PF00179	0.532
TRG_DiLeu_BaLyEn_6	284	289	PF01217	0.616
TRG_ENDOCYTIC_2	140	143	PF00928	0.486
TRG_ENDOCYTIC_2	314	317	PF00928	0.508
TRG_ENDOCYTIC_2	73	76	PF00928	0.507
TRG_NES_CRM1_1	85	99	PF08389	0.493
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.519
TRG_Pf-PMV_PEXEL_1	84	88	PF00026	0.506

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P436	Leptomonas seymouri	62%	95%
A0A3Q8IG34	Leishmania donovani	90%	99%
A4HIS0	Leishmania braziliensis	76%	100%
A4I616	Leishmania infantum	90%	99%
Q4Q6V7	Leishmania major	89%	100%