Glutamate--tRNA ligase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glutamyl-tRNA synthetase, putative

Species:

Leishmania mexicana

UniProt:

E9B199_LEIMU

TriTrypDb:

LmxM.29.3240

Length:

594

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 4
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	11
GO:0110165	cellular anatomical entity	1	12
GO:0005829	cytosol	2	1
GO:0017102	methionyl glutamyl tRNA synthetase complex	2	1
GO:0032991	protein-containing complex	1	1

Expansion

Sequence features

E9B199

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B199

Function

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	12
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006399	tRNA metabolic process	7	12
GO:0006418	tRNA aminoacylation for protein translation	6	12
GO:0006424	glutamyl-tRNA aminoacylation	7	12
GO:0006520	amino acid metabolic process	3	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0016070	RNA metabolic process	5	12
GO:0019752	carboxylic acid metabolic process	5	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0034660	ncRNA metabolic process	6	12
GO:0043038	amino acid activation	4	12
GO:0043039	tRNA aminoacylation	5	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043436	oxoacid metabolic process	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044281	small molecule metabolic process	2	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1901564	organonitrogen compound metabolic process	3	12

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0004812	aminoacyl-tRNA ligase activity	4	12
GO:0004818	glutamate-tRNA ligase activity	5	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016874	ligase activity	2	12
GO:0016875	ligase activity, forming carbon-oxygen bonds	3	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140098	catalytic activity, acting on RNA	3	12
GO:0140101	catalytic activity, acting on a tRNA	4	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	542	546	PF00656	0.395
CLV_NRD_NRD_1	2	4	PF00675	0.718
CLV_NRD_NRD_1	265	267	PF00675	0.259
CLV_NRD_NRD_1	313	315	PF00675	0.259
CLV_NRD_NRD_1	524	526	PF00675	0.259
CLV_PCSK_KEX2_1	2	4	PF00082	0.718
CLV_PCSK_KEX2_1	285	287	PF00082	0.259
CLV_PCSK_KEX2_1	313	315	PF00082	0.259
CLV_PCSK_KEX2_1	431	433	PF00082	0.363
CLV_PCSK_KEX2_1	524	526	PF00082	0.259
CLV_PCSK_KEX2_1	576	578	PF00082	0.461
CLV_PCSK_PC1ET2_1	285	287	PF00082	0.259
CLV_PCSK_PC1ET2_1	431	433	PF00082	0.346
CLV_PCSK_PC1ET2_1	576	578	PF00082	0.461
CLV_PCSK_PC7_1	309	315	PF00082	0.259
CLV_PCSK_SKI1_1	16	20	PF00082	0.559
CLV_PCSK_SKI1_1	174	178	PF00082	0.350
CLV_PCSK_SKI1_1	285	289	PF00082	0.270
CLV_PCSK_SKI1_1	314	318	PF00082	0.237
CLV_PCSK_SKI1_1	428	432	PF00082	0.353
CLV_PCSK_SKI1_1	46	50	PF00082	0.291
CLV_PCSK_SKI1_1	537	541	PF00082	0.352
CLV_PCSK_SKI1_1	577	581	PF00082	0.453
CLV_PCSK_SKI1_1	65	69	PF00082	0.190
CLV_PCSK_SKI1_1	80	84	PF00082	0.259
DEG_Nend_UBRbox_1	1	4	PF02207	0.620
DOC_ANK_TNKS_1	366	373	PF00023	0.470
DOC_CYCLIN_RxL_1	13	23	PF00134	0.612
DOC_MAPK_gen_1	2	11	PF00069	0.536
DOC_MAPK_gen_1	515	522	PF00069	0.472
DOC_MAPK_gen_1	534	543	PF00069	0.304
DOC_MAPK_MEF2A_6	5	13	PF00069	0.473
DOC_MAPK_MEF2A_6	534	543	PF00069	0.417
DOC_MAPK_RevD_3	468	484	PF00069	0.471
DOC_PP1_RVXF_1	330	337	PF00149	0.459
DOC_PP1_RVXF_1	456	462	PF00149	0.464
DOC_PP4_FxxP_1	229	232	PF00568	0.459
DOC_USP7_MATH_1	190	194	PF00917	0.557
DOC_USP7_MATH_1	487	491	PF00917	0.520
DOC_USP7_MATH_1	53	57	PF00917	0.459
DOC_USP7_MATH_1	590	594	PF00917	0.535
DOC_USP7_UBL2_3	381	385	PF12436	0.473
DOC_USP7_UBL2_3	393	397	PF12436	0.438
DOC_USP7_UBL2_3	454	458	PF12436	0.459
DOC_USP7_UBL2_3	534	538	PF12436	0.371
DOC_USP7_UBL2_3	561	565	PF12436	0.484
DOC_USP7_UBL2_3	576	580	PF12436	0.489
DOC_USP7_UBL2_3	584	588	PF12436	0.531
DOC_WW_Pin1_4	141	146	PF00397	0.470
DOC_WW_Pin1_4	209	214	PF00397	0.463
DOC_WW_Pin1_4	351	356	PF00397	0.439
LIG_14-3-3_CanoR_1	356	360	PF00244	0.459
LIG_14-3-3_CanoR_1	367	371	PF00244	0.459
LIG_APCC_ABBA_1	444	449	PF00400	0.484
LIG_BIR_III_2	436	440	PF00653	0.563
LIG_BIR_III_4	261	265	PF00653	0.526
LIG_BRCT_BRCA1_1	119	123	PF00533	0.563
LIG_BRCT_BRCA1_1	332	336	PF00533	0.506
LIG_Clathr_ClatBox_1	82	86	PF01394	0.526
LIG_CSL_BTD_1	460	463	PF09270	0.526
LIG_deltaCOP1_diTrp_1	338	345	PF00928	0.459
LIG_eIF4E_1	77	83	PF01652	0.526
LIG_FHA_1	105	111	PF00498	0.484
LIG_FHA_1	239	245	PF00498	0.494
LIG_FHA_1	287	293	PF00498	0.459
LIG_FHA_1	361	367	PF00498	0.541
LIG_FHA_1	441	447	PF00498	0.543
LIG_FHA_2	142	148	PF00498	0.459
LIG_FHA_2	416	422	PF00498	0.470
LIG_FHA_2	470	476	PF00498	0.563
LIG_LIR_Apic_2	226	232	PF02991	0.459
LIG_LIR_Apic_2	298	303	PF02991	0.459
LIG_LIR_Gen_1	120	130	PF02991	0.462
LIG_LIR_Gen_1	271	280	PF02991	0.459
LIG_LIR_Gen_1	338	347	PF02991	0.505
LIG_LIR_Gen_1	354	364	PF02991	0.584
LIG_LIR_Gen_1	475	480	PF02991	0.459
LIG_LIR_Gen_1	56	66	PF02991	0.459
LIG_LIR_Nem_3	119	125	PF02991	0.459
LIG_LIR_Nem_3	271	276	PF02991	0.459
LIG_LIR_Nem_3	338	342	PF02991	0.492
LIG_LIR_Nem_3	354	360	PF02991	0.578
LIG_LIR_Nem_3	475	479	PF02991	0.459
LIG_LIR_Nem_3	56	61	PF02991	0.459
LIG_MAD2	295	303	PF02301	0.412
LIG_MLH1_MIPbox_1	119	123	PF16413	0.563
LIG_Pex14_1	422	426	PF04695	0.459
LIG_Pex14_2	123	127	PF04695	0.541
LIG_Pex14_2	457	461	PF04695	0.563
LIG_PTB_Apo_2	19	26	PF02174	0.591
LIG_SH2_CRK	357	361	PF00017	0.459
LIG_SH2_CRK	476	480	PF00017	0.474
LIG_SH2_GRB2like	344	347	PF00017	0.526
LIG_SH2_GRB2like	476	479	PF00017	0.474
LIG_SH2_NCK_1	357	361	PF00017	0.459
LIG_SH2_STAP1	118	122	PF00017	0.484
LIG_SH2_STAP1	476	480	PF00017	0.459
LIG_SH2_STAP1	501	505	PF00017	0.492
LIG_SH2_STAT5	122	125	PF00017	0.515
LIG_SH2_STAT5	140	143	PF00017	0.390
LIG_SH2_STAT5	24	27	PF00017	0.637
LIG_SH2_STAT5	344	347	PF00017	0.506
LIG_SH2_STAT5	357	360	PF00017	0.404
LIG_SH2_STAT5	426	429	PF00017	0.484
LIG_SH2_STAT5	528	531	PF00017	0.459
LIG_SH2_STAT5	559	562	PF00017	0.474
LIG_SH3_3	219	225	PF00018	0.506
LIG_SH3_3	300	306	PF00018	0.459
LIG_SH3_3	349	355	PF00018	0.462
LIG_SH3_3	442	448	PF00018	0.550
LIG_SH3_4	381	388	PF00018	0.550
LIG_SUMO_SIM_anti_2	406	413	PF11976	0.466
LIG_SUMO_SIM_anti_2	415	421	PF11976	0.455
LIG_SUMO_SIM_anti_2	508	515	PF11976	0.563
LIG_SUMO_SIM_par_1	469	475	PF11976	0.553
LIG_SUMO_SIM_par_1	539	545	PF11976	0.473
LIG_TRAF2_1	100	103	PF00917	0.573
LIG_TRAF2_1	145	148	PF00917	0.459
LIG_TRAF2_1	165	168	PF00917	0.373
LIG_UBA3_1	9	16	PF00899	0.632
MOD_CDK_SPK_2	141	146	PF00069	0.470
MOD_CDK_SPK_2	351	356	PF00069	0.439
MOD_CDK_SPxxK_3	209	216	PF00069	0.463
MOD_CK1_1	281	287	PF00069	0.563
MOD_CK1_1	499	505	PF00069	0.523
MOD_CK2_1	141	147	PF00069	0.459
MOD_CK2_1	162	168	PF00069	0.496
MOD_CK2_1	37	43	PF00069	0.425
MOD_CK2_1	469	475	PF00069	0.563
MOD_GlcNHglycan	433	436	PF01048	0.284
MOD_GlcNHglycan	54	58	PF01048	0.247
MOD_GlcNHglycan	553	556	PF01048	0.414
MOD_GlcNHglycan	567	570	PF01048	0.545
MOD_GSK3_1	16	23	PF00069	0.630
MOD_GSK3_1	351	358	PF00069	0.439
MOD_GSK3_1	391	398	PF00069	0.484
MOD_LATS_1	14	20	PF00433	0.660
MOD_LATS_1	384	390	PF00433	0.506
MOD_N-GLC_1	209	214	PF02516	0.228
MOD_NEK2_1	18	23	PF00069	0.611
MOD_NEK2_1	278	283	PF00069	0.488
MOD_NEK2_1	291	296	PF00069	0.501
MOD_NEK2_1	330	335	PF00069	0.476
MOD_NEK2_1	337	342	PF00069	0.447
MOD_NEK2_1	37	42	PF00069	0.496
MOD_NEK2_1	457	462	PF00069	0.573
MOD_NEK2_1	85	90	PF00069	0.534
MOD_PIKK_1	499	505	PF00454	0.484
MOD_PK_1	162	168	PF00069	0.502
MOD_PKA_1	431	437	PF00069	0.563
MOD_PKA_1	565	571	PF00069	0.639
MOD_PKA_2	355	361	PF00069	0.459
MOD_PKA_2	366	372	PF00069	0.464
MOD_PKA_2	431	437	PF00069	0.473
MOD_Plk_1	162	168	PF00069	0.484
MOD_Plk_1	271	277	PF00069	0.459
MOD_Plk_1	278	284	PF00069	0.459
MOD_Plk_1	415	421	PF00069	0.459
MOD_Plk_1	440	446	PF00069	0.515
MOD_Plk_1	487	493	PF00069	0.485
MOD_Plk_2-3	415	421	PF00069	0.470
MOD_Plk_4	20	26	PF00069	0.623
MOD_Plk_4	278	284	PF00069	0.484
MOD_Plk_4	355	361	PF00069	0.470
MOD_Plk_4	391	397	PF00069	0.484
MOD_Plk_4	415	421	PF00069	0.501
MOD_Plk_4	440	446	PF00069	0.529
MOD_Plk_4	457	463	PF00069	0.434
MOD_Plk_4	509	515	PF00069	0.559
MOD_ProDKin_1	141	147	PF00069	0.470
MOD_ProDKin_1	209	215	PF00069	0.463
MOD_ProDKin_1	351	357	PF00069	0.439
MOD_SUMO_for_1	316	319	PF00179	0.541
MOD_SUMO_rev_2	377	383	PF00179	0.602
MOD_SUMO_rev_2	449	455	PF00179	0.508
MOD_SUMO_rev_2	531	540	PF00179	0.508
MOD_SUMO_rev_2	75	82	PF00179	0.506
MOD_SUMO_rev_2	98	108	PF00179	0.550
TRG_DiLeu_BaEn_1	406	411	PF01217	0.459
TRG_DiLeu_BaEn_1	475	480	PF01217	0.462
TRG_DiLeu_BaEn_1	536	541	PF01217	0.501
TRG_DiLeu_BaEn_2	53	59	PF01217	0.459
TRG_DiLeu_BaEn_4	167	173	PF01217	0.502
TRG_DiLeu_BaEn_4	32	38	PF01217	0.502
TRG_ENDOCYTIC_2	122	125	PF00928	0.459
TRG_ENDOCYTIC_2	256	259	PF00928	0.468
TRG_ENDOCYTIC_2	280	283	PF00928	0.459
TRG_ENDOCYTIC_2	357	360	PF00928	0.459
TRG_ENDOCYTIC_2	476	479	PF00928	0.459
TRG_ENDOCYTIC_2	527	530	PF00928	0.459
TRG_ER_diArg_1	1	3	PF00400	0.713
TRG_ER_diArg_1	312	314	PF00400	0.459
TRG_NES_CRM1_1	184	196	PF08389	0.474
TRG_Pf-PMV_PEXEL_1	71	75	PF00026	0.306

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4H9	Leptomonas seymouri	86%	100%
A0A0N1PDG1	Leptomonas seymouri	32%	100%
A0A0S4JKF2	Bodo saltans	32%	100%
A0A0S4KIR8	Bodo saltans	70%	95%
A0A1X0NUJ0	Trypanosomatidae	31%	100%
A0A1X0P200	Trypanosomatidae	72%	100%
A0A3Q8IA66	Leishmania donovani	32%	100%
A0A3S7X3T9	Leishmania donovani	97%	100%
A0A422NC24	Trypanosoma rangeli	32%	100%
A0A422P0U9	Trypanosoma rangeli	70%	100%
A0B966	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	31%	100%
A0RY20	Cenarchaeum symbiosum (strain A)	32%	100%
A1A8U7	Escherichia coli O1:K1 / APEC	36%	100%
A1JQH0	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	35%	100%
A1RRG7	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	31%	100%
A1RYD7	Thermofilum pendens (strain DSM 2475 / Hrk 5)	34%	100%
A1SS83	Psychromonas ingrahamii (strain 37)	32%	100%
A2BK91	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	31%	100%
A3DMR5	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	28%	100%
A3MV95	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	31%	100%
A4FXG8	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	27%	100%
A4H8B1	Leishmania braziliensis	32%	100%
A4HIR3	Leishmania braziliensis	91%	100%
A4HWN1	Leishmania infantum	32%	100%
A4I608	Leishmania infantum	96%	100%
A4SZM1	Polynucleobacter asymbioticus (strain DSM 18221 / CIP 109841 / QLW-P1DMWA-1)	31%	100%
A4TNX8	Yersinia pestis (strain Pestoides F)	35%	100%
A4VL72	Pseudomonas stutzeri (strain A1501)	34%	100%
A4W846	Enterobacter sp. (strain 638)	35%	100%
A4WKI4	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	27%	100%
A4XVG2	Pseudomonas mendocina (strain ymp)	33%	100%
A4YIL8	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	30%	100%
A5F2T1	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	35%	100%
A5N6Y3	Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)	36%	100%
A5UN79	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	30%	100%
A6T6C3	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	35%	100%
A6VFU7	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	28%	100%
A6VP11	Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z)	36%	100%
A7FKU1	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	35%	100%
A7IAG1	Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)	29%	94%
A7MQT2	Cronobacter sakazakii (strain ATCC BAA-894)	35%	100%
A7MT45	Vibrio campbellii (strain ATCC BAA-1116)	35%	100%
A7ZJ63	Escherichia coli O139:H28 (strain E24377A / ETEC)	36%	100%
A7ZXU0	Escherichia coli O9:H4 (strain HS)	36%	100%
A8AJD6	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	35%	100%
A8GB43	Serratia proteamaculans (strain 568)	35%	100%
A8M9D7	Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)	26%	100%
A9A423	Nitrosopumilus maritimus (strain SCM1)	33%	100%
A9AAT7	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	28%	100%
A9CSU5	Enterocytozoon bieneusi (strain H348)	30%	86%
A9CSZ1	Enterocytozoon bieneusi (strain H348)	42%	94%
A9MKA7	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	35%	100%
A9MUG5	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	35%	100%
A9R7G5	Yersinia pestis bv. Antiqua (strain Angola)	35%	100%
B0R4Z6	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	28%	100%
B0U6D0	Xylella fastidiosa (strain M12)	33%	100%
B1IY48	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	36%	100%
B1JG85	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	35%	100%
B1L5U2	Korarchaeum cryptofilum (strain OPF8)	33%	100%
B1LLC4	Escherichia coli (strain SMS-3-5 / SECEC)	36%	100%
B1X6L3	Escherichia coli (strain K12 / DH10B)	36%	100%
B1XW11	Polynucleobacter necessarius subsp. necessarius (strain STIR1)	31%	100%
B1YAX4	Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)	31%	100%
B2K8A4	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	35%	100%
B2TU51	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	36%	100%
B2U846	Ralstonia pickettii (strain 12J)	33%	100%
B2VBN3	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	34%	100%
B3R5N3	Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1)	33%	100%
B4EV71	Proteus mirabilis (strain HI4320)	35%	100%
B4RYH7	Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)	35%	100%
B4SYN9	Salmonella newport (strain SL254)	35%	100%
B4TB84	Salmonella heidelberg (strain SL476)	35%	100%
B4TQ00	Salmonella schwarzengrund (strain CVM19633)	35%	100%
B5BCC3	Salmonella paratyphi A (strain AKU_12601)	35%	100%
B5EEE6	Citrifermentans bemidjiense (strain ATCC BAA-1014 / DSM 16622 / JCM 12645 / Bem)	25%	100%
B5EZC3	Salmonella agona (strain SL483)	35%	100%
B5FC12	Aliivibrio fischeri (strain MJ11)	34%	100%
B5FNC1	Salmonella dublin (strain CT_02021853)	35%	100%
B5QWD0	Salmonella enteritidis PT4 (strain P125109)	35%	100%
B5R651	Salmonella gallinarum (strain 287/91 / NCTC 13346)	35%	100%
B5XZG7	Klebsiella pneumoniae (strain 342)	36%	100%
B5YQM4	Escherichia coli O157:H7 (strain EC4115 / EHEC)	36%	100%
B6EHL7	Aliivibrio salmonicida (strain LFI1238)	33%	100%
B6HYN9	Escherichia coli (strain SE11)	36%	100%
B6YSY7	Thermococcus onnurineus (strain NA1)	30%	100%
B7L9L7	Escherichia coli (strain 55989 / EAEC)	36%	100%
B7LKT3	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	36%	100%
B7M5J8	Escherichia coli O8 (strain IAI1)	36%	100%
B7MFU7	Escherichia coli O45:K1 (strain S88 / ExPEC)	36%	100%
B7MPI5	Escherichia coli O81 (strain ED1a)	36%	100%
B7N9S6	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	36%	100%
B7NMN1	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	36%	100%
B7UKW1	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	36%	100%
B7VB85	Pseudomonas aeruginosa (strain LESB58)	34%	100%
B7VIH6	Vibrio atlanticus (strain LGP32)	33%	100%
B8D7U5	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)	30%	100%
B8D9J3	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)	30%	100%
C0PWA7	Salmonella paratyphi C (strain RKS4594)	35%	100%
C1DHE5	Azotobacter vinelandii (strain DJ / ATCC BAA-1303)	33%	100%
C3LTP5	Vibrio cholerae serotype O1 (strain M66-2)	35%	100%
C4K4J9	Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)	34%	100%
C4L887	Tolumonas auensis (strain DSM 9187 / TA4)	35%	100%
C4V819	Nosema ceranae (strain BRL01)	30%	85%
C4VBI7	Nosema ceranae (strain BRL01)	42%	97%
C4ZWF6	Escherichia coli (strain K12 / MC4100 / BW2952)	36%	100%
C5BGA4	Edwardsiella ictaluri (strain 93-146)	34%	100%
C6DBY6	Pectobacterium carotovorum subsp. carotovorum (strain PC1)	35%	100%
C9ZRD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	98%
C9ZXQ5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	90%
E9AQD9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
G9N4A3	Hypocrea virens (strain Gv29-8 / FGSC 10586)	31%	92%
O13775	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	47%	83%
O29979	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	30%	100%
O59314	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	33%	100%
O62431	Caenorhabditis elegans	35%	76%
O82462	Arabidopsis thaliana	49%	83%
P00962	Escherichia coli (strain K12)	36%	100%
P13188	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	73%
P14325	Dictyostelium discoideum	32%	76%
P43831	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	34%	100%
P46655	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	48%	84%
P47897	Homo sapiens	35%	77%
P52780	Lupinus luteus	36%	75%
P56926	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	31%	70%
P56927	Neisseria meningitidis serogroup B (strain MC58)	35%	100%
P57000	Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)	35%	100%
P57490	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	30%	100%
P57847	Pasteurella multocida (strain Pm70)	35%	100%
P95968	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	27%	100%
Q02KT5	Pseudomonas aeruginosa (strain UCBPP-PA14)	34%	100%
Q0I858	Synechococcus sp. (strain CC9311)	22%	100%
Q0K808	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	33%	100%
Q0SVB1	Clostridium perfringens (strain SM101 / Type A)	35%	100%
Q0T6S8	Shigella flexneri serotype 5b (strain 8401)	36%	100%
Q0TK03	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	36%	100%
Q0TTG1	Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)	35%	100%
Q0W8L2	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	29%	100%
Q15TT6	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)	34%	100%
Q188C8	Clostridioides difficile (strain 630)	33%	100%
Q18GA5	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	27%	100%
Q1C540	Yersinia pestis bv. Antiqua (strain Antiqua)	35%	100%
Q1CKN4	Yersinia pestis bv. Antiqua (strain Nepal516)	35%	100%
Q1LQ72	Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)	34%	100%
Q1QMM1	Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)	31%	100%
Q1REN7	Escherichia coli (strain UTI89 / UPEC)	36%	100%
Q2KVX0	Bordetella avium (strain 197N)	33%	100%
Q2NFU2	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	32%	100%
Q2NUP0	Sodalis glossinidius (strain morsitans)	33%	100%
Q2NZL7	Xanthomonas oryzae pv. oryzae (strain MAFF 311018)	33%	100%
Q324M4	Shigella boydii serotype 4 (strain Sb227)	35%	100%
Q32IQ0	Shigella dysenteriae serotype 1 (strain Sd197)	36%	100%
Q3BX52	Xanthomonas campestris pv. vesicatoria (strain 85-10)	33%	100%
Q3IGW8	Pseudoalteromonas translucida (strain TAC 125)	33%	100%
Q3MHH4	Bos taurus	34%	77%
Q3SRI8	Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)	32%	100%
Q3Z4C0	Shigella sonnei (strain Ss046)	36%	100%
Q46CG5	Methanosarcina barkeri (strain Fusaro / DSM 804)	30%	100%
Q47Z40	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	34%	100%
Q4J8P2	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	29%	100%
Q4Q6W5	Leishmania major	95%	100%
Q4QF36	Leishmania major	32%	100%
Q4QK64	Haemophilus influenzae (strain 86-028NP)	34%	100%
Q4UR70	Xanthomonas campestris pv. campestris (strain 8004)	33%	100%
Q50543	Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)	30%	100%
Q54KB8	Dictyostelium discoideum	43%	78%
Q57RP8	Salmonella choleraesuis (strain SC-B67)	35%	100%
Q58772	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	31%	100%
Q5E6P2	Aliivibrio fischeri (strain ATCC 700601 / ES114)	34%	100%
Q5F7G0	Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)	34%	100%
Q5GWF4	Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)	33%	100%
Q5JH16	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	31%	100%
Q5PCH8	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	35%	100%
Q5QXQ2	Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)	36%	100%
Q5V5N9	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	29%	100%
Q66DC5	Yersinia pseudotuberculosis serotype I (strain IP32953)	35%	100%
Q66H61	Rattus norvegicus	34%	77%
Q6D7J7	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	34%	100%
Q6L0N9	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	25%	100%
Q6LTD1	Photobacterium profundum (strain SS9)	35%	100%
Q6LYI0	Methanococcus maripaludis (strain S2 / LL)	27%	100%
Q7MMQ4	Vibrio vulnificus (strain YJ016)	35%	100%
Q7N743	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	34%	100%
Q7NX86	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	33%	100%
Q7UX42	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	34%	99%
Q7VLM3	Haemophilus ducreyi (strain 35000HP / ATCC 700724)	36%	100%
Q7VU94	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	33%	100%
Q7W4T0	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	33%	100%
Q7WGA6	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	33%	100%
Q81ZS7	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)	33%	100%
Q83LY4	Shigella flexneri	36%	100%
Q87DU6	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	33%	100%
Q87RG4	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	36%	100%
Q87YQ1	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	33%	100%
Q88IU5	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	34%	100%
Q89AD4	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	31%	100%
Q89KR6	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	32%	100%
Q8BML9	Mus musculus	34%	77%
Q8EG26	Shewanella oneidensis (strain MR-1)	34%	100%
Q8FJW4	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	36%	100%
Q8K9E1	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	32%	100%
Q8PCB3	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	33%	100%
Q8PNZ5	Xanthomonas axonopodis pv. citri (strain 306)	33%	100%
Q8PW52	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	29%	100%
Q8SR10	Encephalitozoon cuniculi (strain GB-M1)	31%	85%
Q8SSE4	Encephalitozoon cuniculi (strain GB-M1)	43%	93%
Q8TXB7	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	31%	100%
Q8U064	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	31%	100%
Q8W4F3	Arabidopsis thaliana	36%	75%
Q8X9H8	Escherichia coli O157:H7	36%	100%
Q8XMP3	Clostridium perfringens (strain 13 / Type A)	35%	100%
Q8Y199	Ralstonia solanacearum (strain GMI1000)	33%	100%
Q8Z8F8	Salmonella typhi	35%	100%
Q8ZDD9	Yersinia pestis	35%	100%
Q8ZQX5	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	35%	100%
Q971D0	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	30%	100%
Q9HJM5	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	29%	100%
Q9HQI1	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	28%	100%
Q9I2U8	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	34%	100%
Q9KTA6	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	35%	100%
Q9PDP1	Xylella fastidiosa (strain 9a5c)	33%	100%
Q9V1E3	Pyrococcus abyssi (strain GE5 / Orsay)	32%	100%
Q9Y105	Drosophila melanogaster	35%	76%
Q9Y9H1	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	31%	100%
V5B4P6	Trypanosoma cruzi	30%	100%
V5BSE6	Trypanosoma cruzi	71%	100%