Glyceraldehyde-3-phosphate dehydrogenase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glyceraldehyde 3-phosphate dehydrogenase, glycosomal

Species:

Leishmania mexicana

UniProt:

E9B170_LEIMU

TriTrypDb:

LmxM.29.2980

Length:

361

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 6

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005777	peroxisome	6	2
GO:0005829	cytosol	2	2
GO:0020015	glycosome	7	2
GO:0042579	microbody	5	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9B170

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B170

Function

Biological processes
Term	Name	Level	Count
GO:0005975	carbohydrate metabolic process	3	7
GO:0005996	monosaccharide metabolic process	3	7
GO:0006006	glucose metabolic process	5	7
GO:0006082	organic acid metabolic process	3	7
GO:0006090	pyruvate metabolic process	7	7
GO:0006091	generation of precursor metabolites and energy	3	7
GO:0006096	glycolytic process	5	7
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006163	purine nucleotide metabolic process	5	7
GO:0006165	obsolete nucleoside diphosphate phosphorylation	6	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006753	nucleoside phosphate metabolic process	4	7
GO:0006757	obsolete ATP generation from ADP	4	7
GO:0006793	phosphorus metabolic process	3	7
GO:0006796	phosphate-containing compound metabolic process	4	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009056	catabolic process	2	7
GO:0009117	nucleotide metabolic process	5	7
GO:0009132	nucleoside diphosphate metabolic process	5	7
GO:0009135	purine nucleoside diphosphate metabolic process	6	7
GO:0009141	nucleoside triphosphate metabolic process	5	7
GO:0009144	purine nucleoside triphosphate metabolic process	6	7
GO:0009150	purine ribonucleotide metabolic process	6	7
GO:0009179	purine ribonucleoside diphosphate metabolic process	7	7
GO:0009185	ribonucleoside diphosphate metabolic process	6	7
GO:0009199	ribonucleoside triphosphate metabolic process	6	7
GO:0009205	purine ribonucleoside triphosphate metabolic process	7	7
GO:0009259	ribonucleotide metabolic process	5	7
GO:0009987	cellular process	1	7
GO:0016052	carbohydrate catabolic process	4	7
GO:0016310	phosphorylation	5	7
GO:0019318	hexose metabolic process	4	7
GO:0019637	organophosphate metabolic process	3	7
GO:0019693	ribose phosphate metabolic process	4	7
GO:0019752	carboxylic acid metabolic process	5	7
GO:0032787	monocarboxylic acid metabolic process	6	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043436	oxoacid metabolic process	4	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044281	small molecule metabolic process	2	7
GO:0046031	ADP metabolic process	7	7
GO:0046034	ATP metabolic process	7	7
GO:0046483	heterocycle metabolic process	3	7
GO:0046939	obsolete nucleotide phosphorylation	6	7
GO:0055086	nucleobase-containing small molecule metabolic process	3	7
GO:0071704	organic substance metabolic process	2	7
GO:0072521	purine-containing compound metabolic process	4	7
GO:1901135	carbohydrate derivative metabolic process	3	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:1901564	organonitrogen compound metabolic process	3	7
GO:1901575	organic substance catabolic process	3	7

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003824	catalytic activity	1	7
GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	6	7
GO:0005488	binding	1	7
GO:0016491	oxidoreductase activity	2	7
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	4	7
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3	7
GO:0036094	small molecule binding	2	7
GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	5	7
GO:0050661	NADP binding	4	7
GO:0051287	NAD binding	4	7
GO:0097159	organic cyclic compound binding	2	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	325	327	PF00082	0.317
CLV_PCSK_PC1ET2_1	325	327	PF00082	0.255
CLV_PCSK_SKI1_1	16	20	PF00082	0.317
CLV_PCSK_SKI1_1	276	280	PF00082	0.304
CLV_PCSK_SKI1_1	287	291	PF00082	0.248
CLV_PCSK_SKI1_1	325	329	PF00082	0.317
CLV_PCSK_SKI1_1	87	91	PF00082	0.317
DEG_APCC_DBOX_1	15	23	PF00400	0.430
DEG_APCC_KENBOX_2	180	184	PF00400	0.492
DEG_COP1_1	245	254	PF00400	0.517
DEG_SCF_FBW7_1	251	257	PF00400	0.517
DOC_CKS1_1	251	256	PF01111	0.517
DOC_MAPK_gen_1	213	222	PF00069	0.517
DOC_MAPK_gen_1	241	249	PF00069	0.517
DOC_MAPK_MEF2A_6	250	258	PF00069	0.566
DOC_PP1_RVXF_1	327	334	PF00149	0.517
DOC_PP4_FxxP_1	249	252	PF00568	0.517
DOC_USP7_MATH_1	254	258	PF00917	0.599
DOC_USP7_MATH_1	66	70	PF00917	0.492
DOC_USP7_UBL2_3	126	130	PF12436	0.468
DOC_USP7_UBL2_3	276	280	PF12436	0.492
DOC_USP7_UBL2_3	325	329	PF12436	0.455
DOC_WW_Pin1_4	152	157	PF00397	0.541
DOC_WW_Pin1_4	250	255	PF00397	0.517
DOC_WW_Pin1_4	67	72	PF00397	0.517
LIG_14-3-3_CanoR_1	307	311	PF00244	0.541
LIG_14-3-3_CanoR_1	59	65	PF00244	0.517
LIG_BIR_II_1	1	5	PF00653	0.476
LIG_BRCT_BRCA1_1	298	302	PF00533	0.517
LIG_EH1_1	341	349	PF00400	0.397
LIG_FHA_1	114	120	PF00498	0.517
LIG_FHA_1	167	173	PF00498	0.476
LIG_FHA_1	251	257	PF00498	0.594
LIG_FHA_1	73	79	PF00498	0.505
LIG_FHA_2	291	297	PF00498	0.558
LIG_LIR_Apic_2	248	252	PF02991	0.517
LIG_LIR_LC3C_4	77	81	PF02991	0.517
LIG_LIR_Nem_3	324	330	PF02991	0.517
LIG_LIR_Nem_3	97	103	PF02991	0.517
LIG_REV1ctd_RIR_1	325	333	PF16727	0.517
LIG_SH2_CRK	53	57	PF00017	0.430
LIG_SH2_GRB2like	334	337	PF00017	0.403
LIG_SH2_STAP1	311	315	PF00017	0.590
LIG_SH2_STAP1	334	338	PF00017	0.391
LIG_SH2_STAP1	340	344	PF00017	0.326
LIG_SH2_STAP1	62	66	PF00017	0.492
LIG_SH2_STAT5	107	110	PF00017	0.517
LIG_SH2_STAT5	197	200	PF00017	0.517
LIG_SH2_STAT5	46	49	PF00017	0.586
LIG_SH2_STAT5	62	65	PF00017	0.379
LIG_SH3_3	248	254	PF00018	0.517
LIG_SUMO_SIM_anti_2	255	260	PF11976	0.517
LIG_SUMO_SIM_anti_2	31	36	PF11976	0.514
LIG_SUMO_SIM_anti_2	77	82	PF11976	0.517
LIG_SUMO_SIM_par_1	257	262	PF11976	0.517
LIG_SUMO_SIM_par_1	33	39	PF11976	0.517
LIG_TRAF2_1	270	273	PF00917	0.492
LIG_UBA3_1	347	354	PF00899	0.258
MOD_CDK_SPxxK_3	67	74	PF00069	0.517
MOD_CK1_1	155	161	PF00069	0.480
MOD_CK1_1	163	169	PF00069	0.340
MOD_CK1_1	306	312	PF00069	0.469
MOD_CK1_1	313	319	PF00069	0.513
MOD_CK1_1	69	75	PF00069	0.514
MOD_CK2_1	267	273	PF00069	0.505
MOD_CK2_1	290	296	PF00069	0.517
MOD_DYRK1A_RPxSP_1	250	254	PF00069	0.517
MOD_GlcNHglycan	134	137	PF01048	0.446
MOD_GlcNHglycan	138	141	PF01048	0.426
MOD_GSK3_1	109	116	PF00069	0.517
MOD_GSK3_1	132	139	PF00069	0.444
MOD_GSK3_1	185	192	PF00069	0.517
MOD_GSK3_1	193	200	PF00069	0.457
MOD_GSK3_1	250	257	PF00069	0.517
MOD_GSK3_1	259	266	PF00069	0.450
MOD_GSK3_1	306	313	PF00069	0.562
MOD_N-GLC_1	163	168	PF02516	0.427
MOD_N-GLC_1	303	308	PF02516	0.303
MOD_NEK2_1	190	195	PF00069	0.517
MOD_PIKK_1	197	203	PF00454	0.499
MOD_PK_1	267	273	PF00069	0.517
MOD_PKA_2	263	269	PF00069	0.517
MOD_PKA_2	306	312	PF00069	0.539
MOD_Plk_1	254	260	PF00069	0.517
MOD_Plk_1	267	273	PF00069	0.420
MOD_Plk_2-3	205	211	PF00069	0.517
MOD_Plk_4	141	147	PF00069	0.447
MOD_Plk_4	254	260	PF00069	0.517
MOD_Plk_4	281	287	PF00069	0.492
MOD_Plk_4	306	312	PF00069	0.517
MOD_Plk_4	329	335	PF00069	0.599
MOD_ProDKin_1	152	158	PF00069	0.546
MOD_ProDKin_1	250	256	PF00069	0.517
MOD_ProDKin_1	67	73	PF00069	0.517
MOD_SUMO_rev_2	306	316	PF00179	0.503
TRG_ENDOCYTIC_2	53	56	PF00928	0.430
TRG_NES_CRM1_1	26	39	PF08389	0.405
TRG_PTS1	358	361	PF00515	0.524

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0H3MAB5	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	49%	100%
A0A0N1PDI1	Leptomonas seymouri	53%	100%
A0A0S4IV72	Bodo saltans	80%	100%
A0A0S4JCP6	Bodo saltans	39%	100%
A0A1X0P1G4	Trypanosomatidae	82%	100%
A0A1X0P6C0	Trypanosomatidae	29%	100%
A0A1X0P8Z3	Trypanosomatidae	52%	100%
A0A3Q8IJ37	Leishmania donovani	53%	100%
A0A3Q8IQ62	Leishmania donovani	29%	100%
A0A3R7KES2	Trypanosoma rangeli	79%	100%
A0A3R7LC67	Trypanosoma rangeli	27%	100%
A0A3R7NEP8	Trypanosoma rangeli	53%	100%
A0A3S7X3R3	Leishmania donovani	95%	100%
A0KGD2	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)	36%	100%
A0L0K7	Shewanella sp. (strain ANA-3)	38%	100%
A0QWW2	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	48%	100%
A1AFB1	Escherichia coli O1:K1 / APEC	37%	100%
A1JPR1	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	38%	100%
A1RN69	Shewanella sp. (strain W3-18-1)	37%	100%
A1S9A4	Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)	38%	100%
A1SVN9	Psychromonas ingrahamii (strain 37)	35%	97%
A2YQT7	Oryza sativa subsp. indica	55%	100%
A3FKF7	Mustela putorius furo	52%	100%
A3QAX7	Shewanella loihica (strain ATCC BAA-1088 / PV-4)	38%	100%
A4HIN0	Leishmania braziliensis	92%	100%
A4HND9	Leishmania braziliensis	27%	97%
A4I5X6	Leishmania infantum	96%	100%
A4IC12	Leishmania infantum	29%	100%
A4IDK9	Leishmania infantum	53%	100%
A4SRF2	Aeromonas salmonicida (strain A449)	37%	100%
A4WE72	Enterobacter sp. (strain 638)	37%	100%
A4Y3R9	Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)	37%	100%
A5F9G1	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	37%	100%
A6TDT2	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	37%	100%
A7MJQ2	Cronobacter sakazakii (strain ATCC BAA-894)	36%	100%
A7MTQ2	Vibrio campbellii (strain ATCC BAA-1116)	37%	100%
A7ZR35	Escherichia coli O139:H28 (strain E24377A / ETEC)	37%	100%
A8A467	Escherichia coli O9:H4 (strain HS)	37%	100%
A8APE1	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	36%	100%
A8H0M9	Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)	36%	100%
A9MRF0	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	37%	100%
A9N3Q6	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	37%	100%
B0B879	Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)	49%	100%
B0TUC0	Shewanella halifaxensis (strain HAW-EB4)	37%	100%
B1IT76	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	37%	100%
B1LDD2	Escherichia coli (strain SMS-3-5 / SECEC)	37%	100%
B1XEL0	Escherichia coli (strain K12 / DH10B)	37%	100%
B2U0U3	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	37%	100%
B2VF24	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	37%	100%
B4EUH7	Proteus mirabilis (strain HI4320)	39%	100%
B4RWC5	Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)	35%	100%
B4T5H2	Salmonella newport (strain SL254)	37%	100%
B4THF4	Salmonella heidelberg (strain SL476)	37%	100%
B4TV39	Salmonella schwarzengrund (strain CVM19633)	37%	100%
B5BFN5	Salmonella paratyphi A (strain AKU_12601)	37%	100%
B5F5J5	Salmonella agona (strain SL483)	37%	100%
B5F9T4	Aliivibrio fischeri (strain MJ11)	36%	100%
B5FUI3	Salmonella dublin (strain CT_02021853)	37%	100%
B5QXJ7	Salmonella enteritidis PT4 (strain P125109)	37%	100%
B5RE31	Salmonella gallinarum (strain 287/91 / NCTC 13346)	38%	100%
B5XUB7	Klebsiella pneumoniae (strain 342)	37%	100%
B5YQB9	Escherichia coli O157:H7 (strain EC4115 / EHEC)	37%	100%
B6EMW1	Aliivibrio salmonicida (strain LFI1238)	36%	100%
B6I761	Escherichia coli (strain SE11)	37%	100%
B7LFI3	Escherichia coli (strain 55989 / EAEC)	37%	100%
B7LPD5	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	37%	100%
B7LQ20	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	52%	100%
B7LYU4	Escherichia coli O8 (strain IAI1)	37%	100%
B7MMA9	Escherichia coli O45:K1 (strain S88 / ExPEC)	37%	100%
B7MZM0	Escherichia coli O81 (strain ED1a)	37%	100%
B7N7H3	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	37%	100%
B7NHY6	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	37%	100%
B7UHW9	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	37%	100%
B8CU41	Shewanella piezotolerans (strain WP3 / JCM 13877)	35%	100%
B8E5U5	Shewanella baltica (strain OS223)	37%	100%
C0PY46	Salmonella paratyphi C (strain RKS4594)	37%	100%
C4L9J3	Tolumonas auensis (strain DSM 9187 / TA4)	36%	100%
C5A0J7	Escherichia coli (strain K12 / MC4100 / BW2952)	37%	100%
C5BAU7	Edwardsiella ictaluri (strain 93-146)	36%	100%
C6DFH8	Pectobacterium carotovorum subsp. carotovorum (strain PC1)	37%	100%
C9ZRA3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	80%	90%
C9ZYJ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
D0A3A8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
E3VWI2	Streptomyces arenae	45%	100%
E9AFV0	Leishmania major	28%	97%
E9AT12	Leishmania mexicana (strain MHOM/GT/2001/U1103)	52%	94%
E9B703	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
I2BA89	Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74)	52%	100%
O01360	Onchocerca volvulus	53%	100%
O09452	Guillardia theta	49%	94%
O13507	Phaffia rhodozyma	56%	100%
O14556	Homo sapiens	54%	88%
O16027	Globodera rostochiensis	53%	100%
O32755	Lactobacillus delbrueckii subsp. bulgaricus	42%	100%
O34425	Bacillus subtilis (strain 168)	47%	100%
O42259	Oncorhynchus mykiss	54%	100%
O43026	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	57%	100%
O44104	Drosophila pseudoobscura pseudoobscura	55%	100%
O44105	Drosophila subobscura	54%	100%
O52631	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	45%	100%
O57479	Columba livia	52%	100%
O59841	Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1)	55%	100%
O67161	Aquifex aeolicus (strain VF5)	48%	100%
O83816	Treponema pallidum (strain Nichols)	63%	100%
O96423	Crithidia fasciculata	87%	100%
O96425	Leptomonas seymouri	86%	100%
P00355	Sus scrofa	51%	100%
P00356	Gallus gallus	53%	100%
P00357	Homarus americanus	56%	100%
P00358	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	53%	100%
P00359	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	52%	100%
P00360	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	53%	100%
P00361	Thermus aquaticus	46%	100%
P00362	Geobacillus stearothermophilus	52%	100%
P04406	Homo sapiens	50%	100%
P04796	Sinapis alba	56%	100%
P04797	Rattus norvegicus	53%	100%
P04970	Caenorhabditis elegans	52%	100%
P07486	Drosophila melanogaster	54%	100%
P07487	Drosophila melanogaster	54%	100%
P08439	Zygosaccharomyces rouxii	54%	100%
P08477	Hordeum vulgare	56%	100%
P08735	Zea mays	56%	100%
P09043	Nicotiana tabacum	45%	92%
P09044	Nicotiana tabacum	45%	82%
P09094	Nicotiana tabacum	54%	100%
P09124	Bacillus subtilis (strain 168)	50%	100%
P09315	Zea mays	47%	90%
P09316	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)	46%	100%
P09317	Ustilago maydis (strain 521 / FGSC 9021)	54%	100%
P0A036	Staphylococcus aureus (strain Mu50 / ATCC 700699)	44%	100%
P0A037	Staphylococcus aureus (strain MW2)	44%	100%
P0A038	Staphylococcus aureus	44%	100%
P0A1P0	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	52%	100%
P0A1P1	Salmonella typhi	52%	100%
P0A9B2	Escherichia coli (strain K12)	52%	100%
P0A9B3	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	52%	100%
P0A9B4	Escherichia coli O157:H7	52%	100%
P0A9B5	Shigella flexneri	52%	100%
P0A9B6	Escherichia coli (strain K12)	37%	100%
P0A9B7	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	37%	100%
P0A9B8	Escherichia coli O157:H7	37%	100%
P0A9B9	Shigella flexneri	37%	100%
P0C0G6	Streptococcus pyogenes	43%	100%
P0C0G7	Streptococcus pyogenes serotype M1	43%	100%
P0C6C2	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	37%	100%
P0C8Z1	Escherichia fergusonii	52%	100%
P0CE13	Chlamydia trachomatis (strain D/UW-3/Cx)	49%	100%
P0CN74	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	55%	100%
P0CN75	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	55%	100%
P0DB18	Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)	43%	100%
P0DB19	Streptococcus pyogenes serotype M3 (strain SSI-1)	43%	100%
P0DJO7	Shimwellia blattae	52%	100%
P10096	Bos taurus	52%	100%
P10097	Trypanosoma brucei brucei	52%	100%
P12858	Pisum sativum	46%	89%
P12859	Pisum sativum	44%	80%
P12860	Spinacia oleracea	46%	80%
P15115	Weizmannia coagulans	47%	100%
P16858	Mus musculus	52%	100%
P17244	Cricetulus griseus	53%	100%
P17329	Caenorhabditis elegans	53%	100%
P17330	Caenorhabditis elegans	53%	100%
P17331	Caenorhabditis elegans	52%	100%
P17721	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	48%	100%
P17729	Trichoderma koningii	53%	100%
P17730	Trichoderma koningii	56%	100%
P17819	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	53%	100%
P17878	Mesembryanthemum crystallinum	56%	100%
P19089	Cryphonectria parasitica	53%	100%
P19866	Spinacia oleracea	46%	90%
P20287	Schistosoma mansoni	54%	100%
P20445	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	55%	100%
P22512	Trypanosoma brucei brucei	79%	100%
P22513	Trypanosoma cruzi	82%	100%
P23722	Priestia megaterium (strain DSM 319 / IMG 1521)	50%	100%
P24163	Klebsiella aerogenes	52%	100%
P24164	Klebsiella pneumoniae	53%	100%
P24166	Serratia marcescens	53%	100%
P24748	Citrobacter freundii	53%	100%
P24750	Atlantibacter hermannii	53%	100%
P24751	Pseudescherichia vulneris	53%	100%
P24753	Serratia odorifera	52%	100%
P25856	Arabidopsis thaliana	46%	91%
P25857	Arabidopsis thaliana	46%	81%
P25858	Arabidopsis thaliana	55%	100%
P25861	Antirrhinum majus	55%	100%
P26517	Hordeum vulgare	56%	100%
P26518	Magnolia liliiflora	55%	100%
P26519	Petroselinum crispum	56%	100%
P26520	Petunia hybrida	55%	100%
P26521	Ranunculus acris	54%	100%
P26988	Phytophthora infestans	53%	100%
P27726	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	46%	100%
P28844	Cochliobolus lunatus	52%	100%
P29272	Cereibacter sphaeroides	48%	100%
P29497	Cochliobolus heterostrophus	53%	100%
P30724	Gracilaria gracilis	45%	87%
P32635	Agaricus bisporus	48%	100%
P32636	Agaricus bisporus	54%	100%
P32637	Podospora anserina	53%	100%
P32638	Schizophyllum commune	54%	100%
P32809	Caenorhabditis briggsae	52%	100%
P32810	Caenorhabditis briggsae	52%	100%
P34783	Atriplex nummularia	56%	100%
P34916	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	54%	100%
P34917	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	47%	100%
P34918	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	39%	100%
P34919	Chondrus crispus	45%	87%
P34920	Chondrus crispus	53%	100%
P34921	Dianthus caryophyllus	55%	100%
P34922	Pisum sativum	55%	100%
P34923	Physcomitrium patens	56%	100%
P34924	Pinus sylvestris	56%	100%
P35143	Colletotrichum gloeosporioides	54%	100%
P44304	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	52%	100%
P46406	Oryctolagus cuniculus	51%	100%
P46713	Mycobacterium leprae (strain TN)	47%	100%
P46795	Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)	47%	100%
P46796	Borrelia hermsii	48%	100%
P47543	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	42%	100%
P48812	Brugia malayi	54%	100%
P49433	Synechocystis sp. (strain PCC 6803 / Kazusa)	54%	100%
P49644	Chlamydomonas reinhardtii	52%	100%
P50321	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	48%	100%
P50322	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	48%	100%
P50362	Chlamydomonas reinhardtii	46%	97%
P51009	Xanthobacter flavus	49%	100%
P51469	Xenopus laevis	53%	100%
P51640	Mesocricetus auratus	51%	100%
P52694	Ralstonia solanacearum (strain GMI1000)	52%	100%
P52987	Lactococcus lactis subsp. lactis (strain IL1403)	42%	100%
P53429	Giardia intestinalis	50%	100%
P53430	Monascus purpureus	55%	100%
P54117	Colletotrichum lindemuthianum	53%	100%
P54118	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	56%	100%
P54226	Streptomyces arenae	44%	100%
P54270	Gracilaria gracilis	55%	100%
P55070	Lactarius deterrimus	52%	100%
P55071	Amanita muscaria	52%	100%
P55971	Helicobacter pylori (strain ATCC 700392 / 26695)	39%	100%
P56649	Panulirus versicolor	54%	100%
P57384	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	49%	100%
P58072	Escherichia coli O157:H7	43%	100%
P58554	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	47%	100%
P58559	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	40%	100%
P64179	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	49%	100%
P64180	Staphylococcus aureus (strain Mu50 / ATCC 700699)	41%	100%
P64181	Staphylococcus aureus (strain MW2)	41%	100%
P68777	Streptococcus pyogenes serotype M18 (strain MGAS8232)	43%	100%
P75358	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	43%	100%
P78958	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	57%	100%
P80505	Synechocystis sp. (strain PCC 6803 / Kazusa)	46%	100%
P80506	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	54%	100%
P80534	Jaculus orientalis	49%	99%
P84998	Kluyveromyces marxianus	52%	100%
P84999	Kluyveromyces marxianus	51%	100%
P87197	Hypocrea atroviridis	54%	100%
P94915	Mycobacterium avium	49%	100%
P99067	Staphylococcus aureus (strain N315)	41%	100%
P99136	Staphylococcus aureus (strain N315)	44%	100%
P9WN82	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	49%	100%
P9WN83	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	49%	100%
Q00301	Boletus edulis	52%	100%
Q00584	Claviceps purpurea (strain 20.1)	53%	100%
Q00640	Blumeria hordei	55%	100%
Q01077	Kluyveromyces marxianus	51%	100%
Q01558	Leishmania mexicana	52%	100%
Q01597	Drosophila hydei	54%	100%
Q01651	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	46%	100%
Q01982	Phanerodontia chrysosporium	53%	100%
Q02PG5	Pseudomonas aeruginosa (strain UCBPP-PA14)	32%	78%
Q05025	Coturnix japonica	53%	100%
Q07234	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	49%	100%
Q087Q7	Shewanella frigidimarina (strain NCIMB 400)	37%	100%
Q09054	Zea mays	56%	100%
Q0HM63	Shewanella sp. (strain MR-4)	38%	100%
Q0HRM3	Shewanella sp. (strain MR-7)	38%	100%
Q0J8A4	Oryza sativa subsp. japonica	55%	100%
Q0T0X3	Shigella flexneri serotype 5b (strain 8401)	37%	100%
Q0TDS9	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	37%	100%
Q12552	Aspergillus niger	56%	100%
Q12QA4	Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)	37%	100%
Q15QK3	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)	38%	100%
Q1CB62	Yersinia pestis bv. Antiqua (strain Antiqua)	37%	100%
Q1CEY2	Yersinia pestis bv. Antiqua (strain Nepal516)	37%	100%
Q1DTF9	Coccidioides immitis (strain RS)	54%	100%
Q1R7A6	Escherichia coli (strain UTI89 / UPEC)	37%	100%
Q27652	Echinococcus multilocularis	49%	100%
Q27890	Leishmania mexicana	94%	100%
Q28259	Canis lupus familiaris	52%	100%
Q28554	Ovis aries	52%	100%
Q2KJE5	Bos taurus	54%	91%
Q2U0J7	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	54%	100%
Q31WI6	Shigella boydii serotype 4 (strain Sb227)	37%	100%
Q32BY7	Shigella dysenteriae serotype 1 (strain Sd197)	37%	100%
Q39769	Ginkgo biloba	57%	100%
Q3ILL8	Pseudoalteromonas translucida (strain TAC 125)	38%	100%
Q3YXU5	Shigella sonnei (strain Ss046)	37%	100%
Q41595	Taxus baccata	55%	100%
Q42671	Craterostigma plantagineum	56%	100%
Q43247	Zea mays	56%	100%
Q47XD5	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	37%	100%
Q48335	Haloarcula vallismortis	40%	100%
Q4KYY3	Spermophilus citellus	52%	100%
Q4MQ58	Bacillus cereus	51%	100%
Q4Q6Z4	Leishmania major	96%	100%
Q4Q6Z5	Leishmania major	95%	100%
Q4R3T1	Macaca fascicularis	55%	88%
Q4U3L0	Glossina morsitans morsitans	55%	100%
Q57K44	Salmonella choleraesuis (strain SC-B67)	37%	100%
Q59199	Bacteroides fragilis (strain YCH46)	52%	100%
Q59309	Clostridium pasteurianum	47%	100%
Q59800	Kitasatospora aureofaciens	47%	100%
Q59906	Streptococcus dysgalactiae subsp. equisimilis	42%	100%
Q5E7R0	Aliivibrio fischeri (strain ATCC 700601 / ES114)	36%	100%
Q5E924	Arabidopsis thaliana	56%	86%
Q5HF86	Staphylococcus aureus (strain COL)	41%	100%
Q5HHP5	Staphylococcus aureus (strain COL)	44%	100%
Q5HNL7	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	41%	100%
Q5HQV4	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	44%	100%
Q5MJ86	Danio rerio	55%	100%
Q5PJI5	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	37%	100%
Q5QVL6	Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)	33%	100%
Q5R2J2	Pelodiscus sinensis	53%	100%
Q5RAB4	Pongo abelii	51%	100%
Q5XDW3	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	43%	100%
Q5XJ10	Danio rerio	53%	100%
Q64467	Mus musculus	53%	82%
Q666Q0	Yersinia pseudotuberculosis serotype I (strain IP32953)	37%	100%
Q6BMK0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	56%	100%
Q6CCU7	Yarrowia lipolytica (strain CLIB 122 / E 150)	55%	100%
Q6CX23	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	52%	100%
Q6D086	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	37%	100%
Q6FPW3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	54%	100%
Q6FSM4	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	53%	100%
Q6G8N9	Staphylococcus aureus (strain MSSA476)	41%	100%
Q6GB58	Staphylococcus aureus (strain MSSA476)	44%	100%
Q6GG19	Staphylococcus aureus (strain MRSA252)	41%	100%
Q6GIL8	Staphylococcus aureus (strain MRSA252)	44%	100%
Q6K5G8	Oryza sativa subsp. japonica	55%	100%
Q6LMN0	Photobacterium profundum (strain SS9)	36%	100%
Q757I2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	53%	100%
Q7CGS4	Yersinia pestis	37%	100%
Q7CPU5	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	37%	100%
Q7FAH2	Oryza sativa subsp. japonica	56%	100%
Q7MHL0	Vibrio vulnificus (strain YJ016)	38%	100%
Q7N7Z6	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	37%	100%
Q829W3	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	52%	100%
Q82IZ2	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	45%	100%
Q87LL0	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	37%	100%
Q89AK1	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	48%	100%
Q8CNY0	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	41%	100%
Q8CPY5	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	44%	100%
Q8DCA1	Vibrio vulnificus (strain CMCP6)	38%	100%
Q8EIB2	Shewanella oneidensis (strain MR-1)	38%	100%
Q8J1H3	Coccidioides posadasii (strain C735)	53%	100%
Q8NK47	Rhizomucor miehei	55%	100%
Q8TFJ2	Omphalotus olearius	53%	100%
Q8VXQ8	COEVA	54%	100%
Q8VXQ9	COEVA	46%	100%
Q8WZN0	Sordaria macrospora	55%	100%
Q8X1X3	Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01)	55%	100%
Q8XGA4	Salmonella typhi	37%	100%
Q92211	Candida albicans (strain WO-1)	56%	100%
Q92243	Lyophyllum shimeji	53%	100%
Q92263	Komagataella pastoris	54%	100%
Q94469	Dictyostelium discoideum	53%	100%
Q96UF1	Mucor circinelloides f. lusitanicus	55%	100%
Q96UF2	Mucor circinelloides f. lusitanicus	56%	100%
Q96US8	Sclerotinia sclerotiorum	55%	100%
Q9C136	Mucor circinelloides f. lusitanicus	57%	100%
Q9ESV6	Rattus norvegicus	54%	84%
Q9FX54	Arabidopsis thaliana	56%	100%
Q9HFX1	Ajellomyces capsulatus	56%	100%
Q9HGY7	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	56%	100%
Q9LPW0	Arabidopsis thaliana	48%	90%
Q9N2D5	Felis catus	51%	100%
Q9N655	Mastigamoeba balamuthi	52%	100%
Q9P8C0	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	53%	100%
Q9PJN6	Chlamydia muridarum (strain MoPn / Nigg)	49%	100%
Q9SAJ6	Arabidopsis thaliana	55%	86%
Q9UR38	Lentinula edodes	53%	100%
Q9UVC0	Wickerhamomyces ciferrii (strain ATCC 14091 / BCRC 22168 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031 F-60-10)	54%	100%
Q9UW96	Pleurotus sajor-caju	53%	100%
Q9Y796	Cutaneotrichosporon curvatum	56%	100%
Q9Z518	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	52%	100%
Q9Z7T0	Chlamydia pneumoniae	52%	100%
Q9ZKT0	Helicobacter pylori (strain J99 / ATCC 700824)	39%	100%
V5B797	Trypanosoma cruzi	80%	100%
V5BG34	Trypanosoma cruzi	28%	100%