Tim44 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B166_LEIMU

TriTrypDb:

LmxM.29.2930

Length:

191


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

E9B166

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B166


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	128	132	PF00656	0.451
CLV_NRD_NRD_1	166	168	PF00675	0.683
CLV_PCSK_KEX2_1	166	168	PF00082	0.675
CLV_PCSK_SKI1_1	101	105	PF00082	0.686
CLV_PCSK_SKI1_1	87	91	PF00082	0.641
DEG_APCC_DBOX_1	9	17	PF00400	0.415
DOC_CYCLIN_yCln2_LP_2	77	83	PF00134	0.397
DOC_MAPK_gen_1	166	177	PF00069	0.500
DOC_PP4_FxxP_1	177	180	PF00568	0.416
DOC_PP4_FxxP_1	187	190	PF00568	0.429
DOC_WW_Pin1_4	95	100	PF00397	0.476
LIG_14-3-3_CanoR_1	10	14	PF00244	0.449
LIG_FHA_1	104	110	PF00498	0.458
LIG_FHA_1	69	75	PF00498	0.467
LIG_FHA_1	76	82	PF00498	0.391
LIG_LIR_Apic_2	184	190	PF02991	0.471
LIG_LIR_Nem_3	159	165	PF02991	0.360
LIG_LIR_Nem_3	26	32	PF02991	0.624
LIG_MYND_1	137	141	PF01753	0.448
LIG_Pex14_2	187	191	PF04695	0.493
LIG_SH2_STAT3	32	35	PF00017	0.428
LIG_SH2_STAT5	27	30	PF00017	0.562
LIG_SH2_STAT5	32	35	PF00017	0.428
LIG_WRC_WIRS_1	104	109	PF05994	0.473
LIG_WRC_WIRS_1	69	74	PF05994	0.455
MOD_CDK_SPxK_1	95	101	PF00069	0.479
MOD_CK1_1	4	10	PF00069	0.562
MOD_CK2_1	148	154	PF00069	0.450
MOD_GlcNHglycan	150	153	PF01048	0.673
MOD_GlcNHglycan	18	21	PF01048	0.424
MOD_GlcNHglycan	3	6	PF01048	0.472
MOD_GlcNHglycan	51	54	PF01048	0.674
MOD_GSK3_1	64	71	PF00069	0.501
MOD_NEK2_1	129	134	PF00069	0.496
MOD_NEK2_1	23	28	PF00069	0.469
MOD_PIKK_1	64	70	PF00454	0.470
MOD_PKA_1	166	172	PF00069	0.477
MOD_PKA_2	166	172	PF00069	0.475
MOD_PKA_2	9	15	PF00069	0.364
MOD_Plk_1	56	62	PF00069	0.470
MOD_Plk_4	23	29	PF00069	0.374
MOD_Plk_4	4	10	PF00069	0.550
MOD_ProDKin_1	95	101	PF00069	0.479
MOD_SUMO_for_1	118	121	PF00179	0.450
TRG_ER_diArg_1	165	167	PF00400	0.469
TRG_NES_CRM1_1	64	75	PF08389	0.391
TRG_Pf-PMV_PEXEL_1	143	147	PF00026	0.675


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCB6	Leptomonas seymouri	64%	100%
A0A0S4ITI4	Bodo saltans	31%	83%
A0A1X0P1H2	Trypanosomatidae	37%	97%
A0A3Q8IJN4	Leishmania donovani	94%	100%
A0A3R7M429	Trypanosoma rangeli	39%	100%
A4HIM7	Leishmania braziliensis	83%	100%
A4I5X2	Leishmania infantum	94%	100%
C9ZR96	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
Q4Q6Z9	Leishmania major	93%	100%