LeishMANIAdb
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F-box domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
F-box domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B136_LEIMU
TriTrypDb:
LmxM.29.2645
Length:
113

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B136
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B136

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 15 17 PF00675 0.496
CLV_NRD_NRD_1 54 56 PF00675 0.496
CLV_PCSK_KEX2_1 15 17 PF00082 0.496
CLV_PCSK_KEX2_1 54 56 PF00082 0.451
LIG_CtBP_PxDLS_1 69 73 PF00389 0.460
LIG_deltaCOP1_diTrp_1 93 100 PF00928 0.639
LIG_FXI_DFP_1 27 31 PF00024 0.651
LIG_LIR_Apic_2 40 46 PF02991 0.489
LIG_LIR_Nem_3 84 90 PF02991 0.737
LIG_SH2_STAT5 43 46 PF00017 0.491
LIG_SH3_3 29 35 PF00018 0.621
LIG_SUMO_SIM_par_1 68 73 PF11976 0.523
MOD_CK1_1 57 63 PF00069 0.462
MOD_GlcNHglycan 107 110 PF01048 0.532
MOD_GlcNHglycan 56 59 PF01048 0.452
MOD_GlcNHglycan 95 98 PF01048 0.656
MOD_GSK3_1 100 107 PF00069 0.712
MOD_GSK3_1 82 89 PF00069 0.553
MOD_NEK2_1 100 105 PF00069 0.705
MOD_NEK2_1 70 75 PF00069 0.586
MOD_NEK2_1 86 91 PF00069 0.689
MOD_PKA_1 54 60 PF00069 0.449
MOD_PKA_2 105 111 PF00069 0.511
MOD_PKA_2 54 60 PF00069 0.449
MOD_Plk_1 82 88 PF00069 0.704
MOD_Plk_4 82 88 PF00069 0.626
MOD_SUMO_rev_2 37 44 PF00179 0.536
TRG_DiLeu_BaEn_1 40 45 PF01217 0.544
TRG_DiLeu_BaEn_3 82 88 PF01217 0.563
TRG_ER_diArg_1 14 16 PF00400 0.487
TRG_ER_diArg_1 53 55 PF00400 0.448

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IJS1 Leptomonas seymouri 50% 100%
A0A3Q8IF33 Leishmania donovani 88% 100%
A4HIJ7 Leishmania braziliensis 76% 100%
A4I5U1 Leishmania infantum 88% 100%
Q4Q730 Leishmania major 87% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS