Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Secreted protein

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9B133_LEIMU

TriTrypDb:

LmxM.29.2621

Length:

226

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 3, no: 0
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

E9B133

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B133

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	25	29	PF00656	0.396
CLV_C14_Caspase3-7	32	36	PF00656	0.330
CLV_NRD_NRD_1	145	147	PF00675	0.521
CLV_NRD_NRD_1	169	171	PF00675	0.482
CLV_PCSK_KEX2_1	145	147	PF00082	0.521
CLV_PCSK_KEX2_1	169	171	PF00082	0.482
CLV_PCSK_SKI1_1	48	52	PF00082	0.504
DEG_Nend_UBRbox_1	1	4	PF02207	0.406
DEG_SPOP_SBC_1	215	219	PF00917	0.583
DOC_MAPK_gen_1	131	141	PF00069	0.243
DOC_MAPK_MEF2A_6	156	165	PF00069	0.273
DOC_PP1_RVXF_1	3	10	PF00149	0.460
DOC_PP2B_LxvP_1	73	76	PF13499	0.278
DOC_SPAK_OSR1_1	129	133	PF12202	0.286
DOC_USP7_MATH_1	11	15	PF00917	0.400
DOC_USP7_MATH_1	149	153	PF00917	0.285
DOC_USP7_MATH_1	23	27	PF00917	0.521
DOC_USP7_UBL2_3	134	138	PF12436	0.283
DOC_WW_Pin1_4	120	125	PF00397	0.324
LIG_14-3-3_CanoR_1	102	111	PF00244	0.255
LIG_14-3-3_CanoR_1	208	213	PF00244	0.658
LIG_14-3-3_CterR_2	222	226	PF00244	0.601
LIG_BIR_III_2	35	39	PF00653	0.294
LIG_FHA_1	103	109	PF00498	0.305
LIG_FHA_1	80	86	PF00498	0.290
LIG_FHA_2	23	29	PF00498	0.394
LIG_LIR_Gen_1	109	119	PF02991	0.343
LIG_LIR_Gen_1	162	171	PF02991	0.327
LIG_LIR_Gen_1	67	76	PF02991	0.265
LIG_LIR_Gen_1	96	103	PF02991	0.281
LIG_LIR_Nem_3	109	114	PF02991	0.358
LIG_LIR_Nem_3	162	167	PF02991	0.319
LIG_LIR_Nem_3	184	189	PF02991	0.260
LIG_LIR_Nem_3	67	73	PF02991	0.318
LIG_LIR_Nem_3	96	100	PF02991	0.274
LIG_NRBOX	17	23	PF00104	0.369
LIG_NRBOX	188	194	PF00104	0.297
LIG_Pex14_1	70	74	PF04695	0.254
LIG_Pex14_2	164	168	PF04695	0.258
LIG_SH2_CRK	111	115	PF00017	0.280
LIG_SH2_CRK	39	43	PF00017	0.276
LIG_SH2_STAP1	86	90	PF00017	0.326
LIG_SH2_STAT3	86	89	PF00017	0.336
LIG_SH2_STAT5	117	120	PF00017	0.254
LIG_SH3_3	175	181	PF00018	0.366
LIG_SH3_3	210	216	PF00018	0.630
LIG_Sin3_3	137	144	PF02671	0.228
LIG_SUMO_SIM_par_1	138	143	PF11976	0.260
LIG_SUMO_SIM_par_1	198	204	PF11976	0.210
LIG_SUMO_SIM_par_1	20	26	PF11976	0.381
LIG_WRC_WIRS_1	202	207	PF05994	0.462
LIG_WRC_WIRS_1	94	99	PF05994	0.291
LIG_WW_2	178	181	PF00397	0.361
MOD_CK1_1	104	110	PF00069	0.251
MOD_CK1_1	204	210	PF00069	0.556
MOD_GlcNHglycan	13	16	PF01048	0.552
MOD_GlcNHglycan	135	138	PF01048	0.500
MOD_GlcNHglycan	142	145	PF01048	0.480
MOD_GlcNHglycan	172	176	PF01048	0.458
MOD_GlcNHglycan	210	213	PF01048	0.423
MOD_GlcNHglycan	25	28	PF01048	0.566
MOD_GlcNHglycan	61	64	PF01048	0.660
MOD_GlcNHglycan	66	69	PF01048	0.485
MOD_GSK3_1	102	109	PF00069	0.275
MOD_GSK3_1	204	211	PF00069	0.568
MOD_GSK3_1	59	66	PF00069	0.372
MOD_GSK3_1	80	87	PF00069	0.332
MOD_NEK2_1	163	168	PF00069	0.269
MOD_NEK2_1	22	27	PF00069	0.540
MOD_PIKK_1	56	62	PF00454	0.342
MOD_PKA_2	101	107	PF00069	0.251
MOD_PKA_2	207	213	PF00069	0.651
MOD_Plk_1	171	177	PF00069	0.256
MOD_Plk_2-3	93	99	PF00069	0.296
MOD_Plk_4	163	169	PF00069	0.271
MOD_Plk_4	181	187	PF00069	0.384
MOD_ProDKin_1	120	126	PF00069	0.321
MOD_SUMO_for_1	130	133	PF00179	0.254
TRG_ENDOCYTIC_2	111	114	PF00928	0.285
TRG_ER_diArg_1	145	147	PF00400	0.398
TRG_ER_diArg_1	168	170	PF00400	0.313
TRG_NES_CRM1_1	93	106	PF08389	0.295

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IK85	Leptomonas seymouri	49%	100%
A4HIJ4	Leishmania braziliensis	73%	100%