TSNAXIP1_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B126_LEIMU

TriTrypDb:

LmxM.29.2560

Length:

1081

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B126

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B126

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	103	107	PF00656	0.601
CLV_C14_Caspase3-7	194	198	PF00656	0.484
CLV_C14_Caspase3-7	538	542	PF00656	0.486
CLV_C14_Caspase3-7	656	660	PF00656	0.559
CLV_NRD_NRD_1	1069	1071	PF00675	0.458
CLV_NRD_NRD_1	122	124	PF00675	0.544
CLV_NRD_NRD_1	425	427	PF00675	0.412
CLV_NRD_NRD_1	461	463	PF00675	0.439
CLV_NRD_NRD_1	493	495	PF00675	0.447
CLV_NRD_NRD_1	496	498	PF00675	0.451
CLV_NRD_NRD_1	555	557	PF00675	0.394
CLV_NRD_NRD_1	593	595	PF00675	0.543
CLV_NRD_NRD_1	597	599	PF00675	0.557
CLV_NRD_NRD_1	697	699	PF00675	0.595
CLV_NRD_NRD_1	751	753	PF00675	0.423
CLV_NRD_NRD_1	887	889	PF00675	0.377
CLV_PCSK_FUR_1	494	498	PF00082	0.428
CLV_PCSK_FUR_1	885	889	PF00082	0.365
CLV_PCSK_KEX2_1	1069	1071	PF00082	0.458
CLV_PCSK_KEX2_1	122	124	PF00082	0.544
CLV_PCSK_KEX2_1	138	140	PF00082	0.616
CLV_PCSK_KEX2_1	258	260	PF00082	0.546
CLV_PCSK_KEX2_1	425	427	PF00082	0.412
CLV_PCSK_KEX2_1	493	495	PF00082	0.431
CLV_PCSK_KEX2_1	496	498	PF00082	0.436
CLV_PCSK_KEX2_1	555	557	PF00082	0.482
CLV_PCSK_KEX2_1	593	595	PF00082	0.560
CLV_PCSK_KEX2_1	597	599	PF00082	0.591
CLV_PCSK_KEX2_1	697	699	PF00082	0.595
CLV_PCSK_KEX2_1	751	753	PF00082	0.423
CLV_PCSK_KEX2_1	871	873	PF00082	0.355
CLV_PCSK_KEX2_1	887	889	PF00082	0.327
CLV_PCSK_PC1ET2_1	138	140	PF00082	0.506
CLV_PCSK_PC1ET2_1	258	260	PF00082	0.546
CLV_PCSK_PC1ET2_1	871	873	PF00082	0.370
CLV_PCSK_PC7_1	421	427	PF00082	0.412
CLV_PCSK_PC7_1	551	557	PF00082	0.493
CLV_PCSK_PC7_1	593	599	PF00082	0.586
CLV_PCSK_SKI1_1	1073	1077	PF00082	0.459
CLV_PCSK_SKI1_1	122	126	PF00082	0.565
CLV_PCSK_SKI1_1	281	285	PF00082	0.497
CLV_PCSK_SKI1_1	425	429	PF00082	0.390
CLV_PCSK_SKI1_1	432	436	PF00082	0.431
CLV_PCSK_SKI1_1	520	524	PF00082	0.495
CLV_PCSK_SKI1_1	888	892	PF00082	0.349
CLV_PCSK_SKI1_1	911	915	PF00082	0.356
DEG_Nend_UBRbox_1	1	4	PF02207	0.558
DEG_ODPH_VHL_1	722	733	PF01847	0.418
DEG_SCF_FBW7_1	547	553	PF00400	0.548
DEG_SPOP_SBC_1	792	796	PF00917	0.450
DOC_CDC14_PxL_1	558	566	PF14671	0.464
DOC_CKS1_1	1017	1022	PF01111	0.443
DOC_CKS1_1	547	552	PF01111	0.555
DOC_CYCLIN_RxL_1	120	128	PF00134	0.556
DOC_CYCLIN_RxL_1	205	215	PF00134	0.534
DOC_CYCLIN_RxL_1	256	265	PF00134	0.385
DOC_CYCLIN_yCln2_LP_2	722	728	PF00134	0.485
DOC_MAPK_gen_1	378	388	PF00069	0.453
DOC_MAPK_gen_1	613	622	PF00069	0.510
DOC_MAPK_MEF2A_6	721	730	PF00069	0.548
DOC_MAPK_MEF2A_6	942	951	PF00069	0.337
DOC_MAPK_NFAT4_5	942	950	PF00069	0.340
DOC_MAPK_RevD_3	737	752	PF00069	0.447
DOC_PP1_RVXF_1	99	105	PF00149	0.471
DOC_PP2B_LxvP_1	108	111	PF13499	0.570
DOC_PP2B_LxvP_1	185	188	PF13499	0.584
DOC_PP2B_LxvP_1	722	725	PF13499	0.543
DOC_PP2B_LxvP_1	726	729	PF13499	0.550
DOC_USP7_MATH_1	1043	1047	PF00917	0.681
DOC_USP7_MATH_1	1061	1065	PF00917	0.277
DOC_USP7_MATH_1	151	155	PF00917	0.540
DOC_USP7_MATH_1	161	165	PF00917	0.669
DOC_USP7_MATH_1	269	273	PF00917	0.500
DOC_USP7_MATH_1	286	290	PF00917	0.307
DOC_USP7_MATH_1	293	297	PF00917	0.383
DOC_USP7_MATH_1	357	361	PF00917	0.518
DOC_USP7_MATH_1	47	51	PF00917	0.766
DOC_USP7_MATH_1	539	543	PF00917	0.660
DOC_USP7_MATH_1	54	58	PF00917	0.608
DOC_USP7_MATH_1	550	554	PF00917	0.471
DOC_USP7_MATH_1	669	673	PF00917	0.520
DOC_USP7_MATH_1	791	795	PF00917	0.482
DOC_USP7_MATH_1	819	823	PF00917	0.382
DOC_USP7_MATH_1	924	928	PF00917	0.561
DOC_USP7_MATH_1	970	974	PF00917	0.448
DOC_WW_Pin1_4	1016	1021	PF00397	0.430
DOC_WW_Pin1_4	19	24	PF00397	0.570
DOC_WW_Pin1_4	546	551	PF00397	0.527
LIG_14-3-3_CanoR_1	1054	1062	PF00244	0.397
LIG_14-3-3_CanoR_1	1069	1073	PF00244	0.508
LIG_14-3-3_CanoR_1	142	150	PF00244	0.488
LIG_14-3-3_CanoR_1	165	171	PF00244	0.482
LIG_14-3-3_CanoR_1	201	210	PF00244	0.535
LIG_14-3-3_CanoR_1	252	257	PF00244	0.548
LIG_14-3-3_CanoR_1	285	294	PF00244	0.357
LIG_14-3-3_CanoR_1	369	375	PF00244	0.535
LIG_14-3-3_CanoR_1	432	438	PF00244	0.459
LIG_14-3-3_CanoR_1	462	470	PF00244	0.447
LIG_14-3-3_CanoR_1	597	605	PF00244	0.590
LIG_14-3-3_CanoR_1	751	755	PF00244	0.349
LIG_14-3-3_CanoR_1	942	946	PF00244	0.465
LIG_14-3-3_CanoR_1	968	973	PF00244	0.500
LIG_AP2alpha_2	586	588	PF02296	0.496
LIG_APCC_ABBA_1	277	282	PF00400	0.379
LIG_APCC_ABBA_1	585	590	PF00400	0.540
LIG_BRCT_BRCA1_1	39	43	PF00533	0.657
LIG_Clathr_ClatBox_1	124	128	PF01394	0.585
LIG_CSL_BTD_1	737	740	PF09270	0.438
LIG_EH1_1	623	631	PF00400	0.464
LIG_eIF4E_1	256	262	PF01652	0.401
LIG_FHA_1	1017	1023	PF00498	0.419
LIG_FHA_1	103	109	PF00498	0.544
LIG_FHA_1	1048	1054	PF00498	0.369
LIG_FHA_1	1075	1081	PF00498	0.462
LIG_FHA_1	167	173	PF00498	0.537
LIG_FHA_1	180	186	PF00498	0.501
LIG_FHA_1	224	230	PF00498	0.586
LIG_FHA_1	377	383	PF00498	0.510
LIG_FHA_1	480	486	PF00498	0.431
LIG_FHA_1	496	502	PF00498	0.590
LIG_FHA_1	53	59	PF00498	0.616
LIG_FHA_1	542	548	PF00498	0.547
LIG_FHA_1	649	655	PF00498	0.716
LIG_FHA_1	72	78	PF00498	0.652
LIG_FHA_1	794	800	PF00498	0.528
LIG_FHA_1	9	15	PF00498	0.600
LIG_FHA_2	330	336	PF00498	0.512
LIG_FHA_2	502	508	PF00498	0.460
LIG_FHA_2	771	777	PF00498	0.500
LIG_FHA_2	811	817	PF00498	0.339
LIG_FHA_2	901	907	PF00498	0.493
LIG_IBAR_NPY_1	278	280	PF08397	0.368
LIG_LIR_Gen_1	296	305	PF02991	0.375
LIG_LIR_Gen_1	317	328	PF02991	0.484
LIG_LIR_Gen_1	429	438	PF02991	0.429
LIG_LIR_Gen_1	472	481	PF02991	0.462
LIG_LIR_Gen_1	929	938	PF02991	0.504
LIG_LIR_Gen_1	946	955	PF02991	0.265
LIG_LIR_Nem_3	282	287	PF02991	0.396
LIG_LIR_Nem_3	289	294	PF02991	0.361
LIG_LIR_Nem_3	296	301	PF02991	0.328
LIG_LIR_Nem_3	317	323	PF02991	0.596
LIG_LIR_Nem_3	40	46	PF02991	0.561
LIG_LIR_Nem_3	429	433	PF02991	0.432
LIG_LIR_Nem_3	445	450	PF02991	0.431
LIG_LIR_Nem_3	553	557	PF02991	0.564
LIG_LIR_Nem_3	559	564	PF02991	0.564
LIG_LIR_Nem_3	929	935	PF02991	0.512
LIG_LIR_Nem_3	946	951	PF02991	0.264
LIG_LYPXL_SIV_4	279	287	PF13949	0.395
LIG_LYPXL_yS_3	561	564	PF13949	0.466
LIG_NRBOX	631	637	PF00104	0.433
LIG_NRBOX	802	808	PF00104	0.358
LIG_PCNA_PIPBox_1	760	769	PF02747	0.290
LIG_Pex14_1	554	558	PF04695	0.478
LIG_SH2_CRK	294	298	PF00017	0.364
LIG_SH2_CRK	305	309	PF00017	0.376
LIG_SH2_CRK	320	324	PF00017	0.425
LIG_SH2_CRK	820	824	PF00017	0.411
LIG_SH2_GRB2like	305	308	PF00017	0.426
LIG_SH2_NCK_1	320	324	PF00017	0.423
LIG_SH2_NCK_1	820	824	PF00017	0.385
LIG_SH2_SRC	305	308	PF00017	0.426
LIG_SH2_SRC	468	471	PF00017	0.452
LIG_SH2_STAP1	294	298	PF00017	0.336
LIG_SH2_STAP1	305	309	PF00017	0.434
LIG_SH2_STAP1	320	324	PF00017	0.397
LIG_SH2_STAP1	430	434	PF00017	0.433
LIG_SH2_STAP1	465	469	PF00017	0.474
LIG_SH2_STAP1	567	571	PF00017	0.524
LIG_SH2_STAP1	78	82	PF00017	0.511
LIG_SH2_STAP1	820	824	PF00017	0.385
LIG_SH2_STAT3	624	627	PF00017	0.472
LIG_SH2_STAT5	19	22	PF00017	0.549
LIG_SH2_STAT5	256	259	PF00017	0.514
LIG_SH2_STAT5	468	471	PF00017	0.437
LIG_SH2_STAT5	624	627	PF00017	0.472
LIG_SH2_STAT5	948	951	PF00017	0.319
LIG_SH3_3	1014	1020	PF00018	0.418
LIG_SH3_3	1033	1039	PF00018	0.509
LIG_SH3_3	145	151	PF00018	0.536
LIG_SH3_3	20	26	PF00018	0.567
LIG_SH3_3	544	550	PF00018	0.543
LIG_SH3_3	609	615	PF00018	0.550
LIG_SH3_3	712	718	PF00018	0.538
LIG_SH3_3	734	740	PF00018	0.478
LIG_SH3_3	851	857	PF00018	0.376
LIG_SUMO_SIM_anti_2	1045	1053	PF11976	0.384
LIG_SUMO_SIM_anti_2	411	417	PF11976	0.416
LIG_SUMO_SIM_anti_2	504	510	PF11976	0.468
LIG_SUMO_SIM_anti_2	862	868	PF11976	0.308
LIG_SUMO_SIM_par_1	1011	1016	PF11976	0.420
LIG_SUMO_SIM_par_1	628	633	PF11976	0.452
LIG_SUMO_SIM_par_1	897	903	PF11976	0.413
LIG_SUMO_SIM_par_1	934	940	PF11976	0.491
LIG_TRAF2_1	332	335	PF00917	0.468
LIG_TRAF2_1	364	367	PF00917	0.386
LIG_TRAF2_1	515	518	PF00917	0.448
LIG_TRAF2_1	672	675	PF00917	0.575
LIG_WRC_WIRS_1	771	776	PF05994	0.255
LIG_WRC_WIRS_1	948	953	PF05994	0.378
LIG_WW_3	855	859	PF00397	0.351
MOD_CDK_SPK_2	546	551	PF00069	0.510
MOD_CK1_1	1074	1080	PF00069	0.428
MOD_CK1_1	203	209	PF00069	0.597
MOD_CK1_1	211	217	PF00069	0.624
MOD_CK1_1	238	244	PF00069	0.643
MOD_CK1_1	24	30	PF00069	0.705
MOD_CK1_1	265	271	PF00069	0.449
MOD_CK1_1	50	56	PF00069	0.630
MOD_CK1_1	57	63	PF00069	0.782
MOD_CK1_1	600	606	PF00069	0.604
MOD_CK1_1	971	977	PF00069	0.508
MOD_CK2_1	329	335	PF00069	0.504
MOD_CK2_1	349	355	PF00069	0.505
MOD_CK2_1	397	403	PF00069	0.531
MOD_CK2_1	532	538	PF00069	0.550
MOD_CK2_1	669	675	PF00069	0.723
MOD_CK2_1	900	906	PF00069	0.390
MOD_CK2_1	97	103	PF00069	0.535
MOD_GlcNHglycan	1007	1011	PF01048	0.369
MOD_GlcNHglycan	1063	1066	PF01048	0.375
MOD_GlcNHglycan	1073	1076	PF01048	0.573
MOD_GlcNHglycan	112	117	PF01048	0.576
MOD_GlcNHglycan	119	122	PF01048	0.452
MOD_GlcNHglycan	179	182	PF01048	0.609
MOD_GlcNHglycan	240	243	PF01048	0.515
MOD_GlcNHglycan	26	29	PF01048	0.488
MOD_GlcNHglycan	264	267	PF01048	0.650
MOD_GlcNHglycan	271	274	PF01048	0.496
MOD_GlcNHglycan	288	291	PF01048	0.471
MOD_GlcNHglycan	49	52	PF01048	0.529
MOD_GlcNHglycan	563	567	PF01048	0.446
MOD_GlcNHglycan	686	690	PF01048	0.706
MOD_GlcNHglycan	710	713	PF01048	0.561
MOD_GlcNHglycan	745	748	PF01048	0.440
MOD_GlcNHglycan	8	11	PF01048	0.625
MOD_GlcNHglycan	920	923	PF01048	0.342
MOD_GlcNHglycan	973	976	PF01048	0.536
MOD_GSK3_1	1043	1050	PF00069	0.455
MOD_GSK3_1	137	144	PF00069	0.674
MOD_GSK3_1	151	158	PF00069	0.460
MOD_GSK3_1	166	173	PF00069	0.557
MOD_GSK3_1	17	24	PF00069	0.693
MOD_GSK3_1	200	207	PF00069	0.667
MOD_GSK3_1	248	255	PF00069	0.402
MOD_GSK3_1	265	272	PF00069	0.474
MOD_GSK3_1	314	321	PF00069	0.438
MOD_GSK3_1	349	356	PF00069	0.576
MOD_GSK3_1	370	377	PF00069	0.598
MOD_GSK3_1	50	57	PF00069	0.719
MOD_GSK3_1	539	546	PF00069	0.688
MOD_GSK3_1	596	603	PF00069	0.593
MOD_GSK3_1	669	676	PF00069	0.600
MOD_GSK3_1	750	757	PF00069	0.418
MOD_GSK3_1	77	84	PF00069	0.616
MOD_GSK3_1	806	813	PF00069	0.285
MOD_GSK3_1	93	100	PF00069	0.514
MOD_GSK3_1	947	954	PF00069	0.271
MOD_GSK3_1	970	977	PF00069	0.483
MOD_N-GLC_1	463	468	PF02516	0.394
MOD_NEK2_1	17	22	PF00069	0.662
MOD_NEK2_1	179	184	PF00069	0.580
MOD_NEK2_1	36	41	PF00069	0.716
MOD_NEK2_1	374	379	PF00069	0.520
MOD_NEK2_1	433	438	PF00069	0.441
MOD_NEK2_1	635	640	PF00069	0.456
MOD_NEK2_1	646	651	PF00069	0.478
MOD_NEK2_1	77	82	PF00069	0.559
MOD_NEK2_1	881	886	PF00069	0.422
MOD_NEK2_1	93	98	PF00069	0.524
MOD_NEK2_1	947	952	PF00069	0.349
MOD_NEK2_2	293	298	PF00069	0.498
MOD_NEK2_2	81	86	PF00069	0.622
MOD_PIKK_1	137	143	PF00454	0.641
MOD_PIKK_1	329	335	PF00454	0.521
MOD_PIKK_1	403	409	PF00454	0.396
MOD_PIKK_1	501	507	PF00454	0.507
MOD_PIKK_1	635	641	PF00454	0.541
MOD_PK_1	968	974	PF00069	0.415
MOD_PKA_1	597	603	PF00069	0.594
MOD_PKA_2	1053	1059	PF00069	0.396
MOD_PKA_2	1068	1074	PF00069	0.510
MOD_PKA_2	141	147	PF00069	0.494
MOD_PKA_2	200	206	PF00069	0.534
MOD_PKA_2	216	222	PF00069	0.518
MOD_PKA_2	397	403	PF00069	0.400
MOD_PKA_2	495	501	PF00069	0.437
MOD_PKA_2	539	545	PF00069	0.597
MOD_PKA_2	550	556	PF00069	0.529
MOD_PKA_2	596	602	PF00069	0.806
MOD_PKA_2	615	621	PF00069	0.412
MOD_PKA_2	693	699	PF00069	0.590
MOD_PKA_2	743	749	PF00069	0.431
MOD_PKA_2	750	756	PF00069	0.340
MOD_PKA_2	85	91	PF00069	0.546
MOD_PKA_2	941	947	PF00069	0.420
MOD_Plk_1	1025	1031	PF00069	0.393
MOD_Plk_1	1047	1053	PF00069	0.394
MOD_Plk_1	342	348	PF00069	0.367
MOD_Plk_1	916	922	PF00069	0.357
MOD_Plk_4	1047	1053	PF00069	0.395
MOD_Plk_4	216	222	PF00069	0.529
MOD_Plk_4	252	258	PF00069	0.407
MOD_Plk_4	293	299	PF00069	0.368
MOD_Plk_4	433	439	PF00069	0.397
MOD_Plk_4	543	549	PF00069	0.543
MOD_Plk_4	755	761	PF00069	0.334
MOD_Plk_4	77	83	PF00069	0.656
MOD_Plk_4	770	776	PF00069	0.429
MOD_Plk_4	947	953	PF00069	0.356
MOD_ProDKin_1	1016	1022	PF00069	0.433
MOD_ProDKin_1	19	25	PF00069	0.570
MOD_ProDKin_1	546	552	PF00069	0.523
MOD_SUMO_for_1	257	260	PF00179	0.395
MOD_SUMO_rev_2	442	450	PF00179	0.382
TRG_DiLeu_BaEn_1	429	434	PF01217	0.379
TRG_DiLeu_BaLyEn_6	1063	1068	PF01217	0.445
TRG_DiLeu_BaLyEn_6	120	125	PF01217	0.543
TRG_DiLeu_BaLyEn_6	726	731	PF01217	0.525
TRG_ENDOCYTIC_2	294	297	PF00928	0.361
TRG_ENDOCYTIC_2	305	308	PF00928	0.375
TRG_ENDOCYTIC_2	320	323	PF00928	0.425
TRG_ENDOCYTIC_2	430	433	PF00928	0.435
TRG_ENDOCYTIC_2	561	564	PF00928	0.639
TRG_ENDOCYTIC_2	764	767	PF00928	0.310
TRG_ENDOCYTIC_2	804	807	PF00928	0.522
TRG_ENDOCYTIC_2	820	823	PF00928	0.308
TRG_ENDOCYTIC_2	948	951	PF00928	0.319
TRG_ER_diArg_1	1068	1070	PF00400	0.466
TRG_ER_diArg_1	122	124	PF00400	0.544
TRG_ER_diArg_1	425	427	PF00400	0.412
TRG_ER_diArg_1	493	495	PF00400	0.426
TRG_ER_diArg_1	554	556	PF00400	0.401
TRG_ER_diArg_1	596	598	PF00400	0.530
TRG_ER_diArg_1	697	699	PF00400	0.562
TRG_ER_diArg_1	885	888	PF00400	0.359
TRG_Pf-PMV_PEXEL_1	123	128	PF00026	0.547
TRG_Pf-PMV_PEXEL_1	361	365	PF00026	0.427
TRG_Pf-PMV_PEXEL_1	425	429	PF00026	0.414
TRG_Pf-PMV_PEXEL_1	555	559	PF00026	0.573
TRG_Pf-PMV_PEXEL_1	875	880	PF00026	0.407

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2U2	Leptomonas seymouri	49%	94%
A0A0S4JIU6	Bodo saltans	27%	100%
A0A3Q8IC50	Leishmania donovani	86%	100%
A4HII7	Leishmania braziliensis	69%	99%
A4I686	Leishmania infantum	86%	100%
Q4Q739	Leishmania major	86%	99%