Source | Evidence on protein | Close homologs |
---|---|---|
Cuervo et al. | no | yes: 0 |
Hassani et al. | no | yes: 0 |
Forrest at al. (metacyclic) | no | yes: 0 |
Forrest at al. (procyclic) | no | yes: 0 |
Silverman et al. | no | yes: 0 |
Pissara et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Pires et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Silverman et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Jamdhade et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
DeepLoc | ||
SignalP6 | no | yes: 0, no: 11 |
NetGPI | no | yes: 0, no: 11 |
Term | Name | Level | Count |
---|---|---|---|
GO:0005737 | cytoplasm | 2 | 1 |
GO:0005783 | endoplasmic reticulum | 5 | 1 |
GO:0043226 | organelle | 2 | 1 |
GO:0043227 | membrane-bounded organelle | 3 | 1 |
GO:0043229 | intracellular organelle | 3 | 1 |
GO:0043231 | intracellular membrane-bounded organelle | 4 | 1 |
GO:0110165 | cellular anatomical entity | 1 | 2 |
GO:0016020 | membrane | 2 | 1 |
Related structures:
AlphaFold database: E9B108
Term | Name | Level | Count |
---|---|---|---|
GO:0006082 | organic acid metabolic process | 3 | 11 |
GO:0008152 | metabolic process | 1 | 11 |
GO:0009987 | cellular process | 1 | 11 |
GO:0019752 | carboxylic acid metabolic process | 5 | 11 |
GO:0043436 | oxoacid metabolic process | 4 | 11 |
GO:0044237 | cellular metabolic process | 2 | 11 |
GO:0044281 | small molecule metabolic process | 2 | 11 |
GO:0071704 | organic substance metabolic process | 2 | 11 |
GO:0006066 | alcohol metabolic process | 3 | 1 |
GO:0006576 | biogenic amine metabolic process | 5 | 1 |
GO:0006580 | ethanolamine metabolic process | 5 | 1 |
GO:0006629 | lipid metabolic process | 3 | 1 |
GO:0006643 | membrane lipid metabolic process | 4 | 1 |
GO:0006665 | sphingolipid metabolic process | 4 | 1 |
GO:0006807 | nitrogen compound metabolic process | 2 | 1 |
GO:0009056 | catabolic process | 2 | 1 |
GO:0009058 | biosynthetic process | 2 | 1 |
GO:0009308 | amine metabolic process | 4 | 1 |
GO:0009309 | amine biosynthetic process | 5 | 1 |
GO:0016042 | lipid catabolic process | 4 | 1 |
GO:0030149 | sphingolipid catabolic process | 5 | 1 |
GO:0034308 | primary alcohol metabolic process | 4 | 1 |
GO:0034309 | primary alcohol biosynthetic process | 5 | 1 |
GO:0034641 | cellular nitrogen compound metabolic process | 3 | 1 |
GO:0042401 | biogenic amine biosynthetic process | 6 | 1 |
GO:0042439 | ethanolamine-containing compound metabolic process | 4 | 1 |
GO:0044238 | primary metabolic process | 2 | 1 |
GO:0044242 | cellular lipid catabolic process | 4 | 1 |
GO:0044248 | cellular catabolic process | 3 | 1 |
GO:0044249 | cellular biosynthetic process | 3 | 1 |
GO:0044255 | cellular lipid metabolic process | 3 | 1 |
GO:0044271 | cellular nitrogen compound biosynthetic process | 4 | 1 |
GO:0044283 | small molecule biosynthetic process | 3 | 1 |
GO:0046165 | alcohol biosynthetic process | 4 | 1 |
GO:0046335 | ethanolamine biosynthetic process | 6 | 1 |
GO:0046466 | membrane lipid catabolic process | 5 | 1 |
GO:1901160 | primary amino compound metabolic process | 4 | 1 |
GO:1901162 | primary amino compound biosynthetic process | 5 | 1 |
GO:1901564 | organonitrogen compound metabolic process | 3 | 1 |
GO:1901565 | organonitrogen compound catabolic process | 4 | 1 |
GO:1901566 | organonitrogen compound biosynthetic process | 4 | 1 |
GO:1901575 | organic substance catabolic process | 3 | 1 |
GO:1901576 | organic substance biosynthetic process | 3 | 1 |
GO:1901615 | organic hydroxy compound metabolic process | 3 | 1 |
GO:1901617 | organic hydroxy compound biosynthetic process | 4 | 1 |
Term | Name | Level | Count |
---|---|---|---|
GO:0003824 | catalytic activity | 1 | 12 |
GO:0005488 | binding | 1 | 11 |
GO:0008117 | sphinganine-1-phosphate aldolase activity | 5 | 8 |
GO:0016829 | lyase activity | 2 | 12 |
GO:0016830 | carbon-carbon lyase activity | 3 | 11 |
GO:0016832 | aldehyde-lyase activity | 4 | 8 |
GO:0019842 | vitamin binding | 3 | 11 |
GO:0030170 | pyridoxal phosphate binding | 4 | 11 |
GO:0036094 | small molecule binding | 2 | 11 |
GO:0043167 | ion binding | 2 | 11 |
GO:0043168 | anion binding | 3 | 11 |
GO:0070279 | vitamin B6 binding | 3 | 11 |
GO:0097159 | organic cyclic compound binding | 2 | 11 |
GO:1901363 | heterocyclic compound binding | 2 | 11 |
Leishmania | From | To | Domain/Motif | Score |
---|---|---|---|---|
CLV_NRD_NRD_1 | 154 | 156 | PF00675 | 0.256 |
CLV_NRD_NRD_1 | 200 | 202 | PF00675 | 0.237 |
CLV_NRD_NRD_1 | 63 | 65 | PF00675 | 0.469 |
CLV_PCSK_SKI1_1 | 115 | 119 | PF00082 | 0.328 |
CLV_PCSK_SKI1_1 | 318 | 322 | PF00082 | 0.350 |
CLV_PCSK_SKI1_1 | 398 | 402 | PF00082 | 0.342 |
CLV_PCSK_SKI1_1 | 500 | 504 | PF00082 | 0.445 |
CLV_PCSK_SKI1_1 | 524 | 528 | PF00082 | 0.347 |
CLV_PCSK_SKI1_1 | 65 | 69 | PF00082 | 0.392 |
CLV_PCSK_SKI1_1 | 84 | 88 | PF00082 | 0.475 |
DOC_CDC14_PxL_1 | 232 | 240 | PF14671 | 0.342 |
DOC_CKS1_1 | 466 | 471 | PF01111 | 0.407 |
DOC_MAPK_gen_1 | 13 | 22 | PF00069 | 0.345 |
DOC_MAPK_gen_1 | 251 | 260 | PF00069 | 0.274 |
DOC_MAPK_gen_1 | 305 | 315 | PF00069 | 0.398 |
DOC_MAPK_MEF2A_6 | 308 | 315 | PF00069 | 0.398 |
DOC_PP2B_LxvP_1 | 58 | 61 | PF13499 | 0.500 |
DOC_PP2B_LxvP_1 | 86 | 89 | PF13499 | 0.541 |
DOC_PP2B_PxIxI_1 | 413 | 419 | PF00149 | 0.272 |
DOC_PP4_FxxP_1 | 298 | 301 | PF00568 | 0.256 |
DOC_USP7_MATH_1 | 145 | 149 | PF00917 | 0.343 |
DOC_USP7_MATH_1 | 366 | 370 | PF00917 | 0.291 |
DOC_USP7_MATH_1 | 422 | 426 | PF00917 | 0.293 |
DOC_USP7_MATH_1 | 428 | 432 | PF00917 | 0.323 |
DOC_USP7_MATH_1 | 504 | 508 | PF00917 | 0.374 |
DOC_USP7_MATH_1 | 89 | 93 | PF00917 | 0.472 |
DOC_USP7_UBL2_3 | 247 | 251 | PF12436 | 0.296 |
DOC_USP7_UBL2_3 | 65 | 69 | PF12436 | 0.418 |
DOC_WW_Pin1_4 | 13 | 18 | PF00397 | 0.507 |
DOC_WW_Pin1_4 | 362 | 367 | PF00397 | 0.272 |
DOC_WW_Pin1_4 | 465 | 470 | PF00397 | 0.398 |
LIG_14-3-3_CanoR_1 | 42 | 48 | PF00244 | 0.575 |
LIG_14-3-3_CanoR_1 | 475 | 483 | PF00244 | 0.353 |
LIG_APCC_ABBA_1 | 287 | 292 | PF00400 | 0.272 |
LIG_APCC_ABBA_1 | 299 | 304 | PF00400 | 0.272 |
LIG_BIR_III_4 | 176 | 180 | PF00653 | 0.272 |
LIG_BRCT_BRCA1_1 | 147 | 151 | PF00533 | 0.316 |
LIG_BRCT_BRCA1_1 | 348 | 352 | PF00533 | 0.272 |
LIG_deltaCOP1_diTrp_1 | 447 | 455 | PF00928 | 0.254 |
LIG_eIF4E_1 | 227 | 233 | PF01652 | 0.256 |
LIG_FHA_1 | 128 | 134 | PF00498 | 0.223 |
LIG_FHA_1 | 16 | 22 | PF00498 | 0.477 |
LIG_FHA_1 | 184 | 190 | PF00498 | 0.272 |
LIG_FHA_1 | 201 | 207 | PF00498 | 0.351 |
LIG_FHA_1 | 239 | 245 | PF00498 | 0.269 |
LIG_FHA_1 | 24 | 30 | PF00498 | 0.446 |
LIG_FHA_1 | 255 | 261 | PF00498 | 0.238 |
LIG_FHA_1 | 335 | 341 | PF00498 | 0.261 |
LIG_FHA_1 | 405 | 411 | PF00498 | 0.256 |
LIG_FHA_1 | 421 | 427 | PF00498 | 0.282 |
LIG_FHA_1 | 428 | 434 | PF00498 | 0.314 |
LIG_FHA_2 | 193 | 199 | PF00498 | 0.376 |
LIG_FHA_2 | 399 | 405 | PF00498 | 0.290 |
LIG_FHA_2 | 77 | 83 | PF00498 | 0.360 |
LIG_FHA_2 | 85 | 91 | PF00498 | 0.328 |
LIG_GBD_Chelix_1 | 101 | 109 | PF00786 | 0.437 |
LIG_LIR_Gen_1 | 349 | 359 | PF02991 | 0.256 |
LIG_LIR_Gen_1 | 380 | 389 | PF02991 | 0.286 |
LIG_LIR_Gen_1 | 45 | 55 | PF02991 | 0.409 |
LIG_LIR_Nem_3 | 226 | 230 | PF02991 | 0.272 |
LIG_LIR_Nem_3 | 250 | 255 | PF02991 | 0.316 |
LIG_LIR_Nem_3 | 349 | 355 | PF02991 | 0.256 |
LIG_LIR_Nem_3 | 45 | 51 | PF02991 | 0.415 |
LIG_LIR_Nem_3 | 80 | 86 | PF02991 | 0.538 |
LIG_MAD2 | 69 | 77 | PF02301 | 0.352 |
LIG_MYND_3 | 300 | 304 | PF01753 | 0.398 |
LIG_PCNA_PIPBox_1 | 1 | 10 | PF02747 | 0.497 |
LIG_PDZ_Class_2 | 532 | 537 | PF00595 | 0.484 |
LIG_Pex14_2 | 298 | 302 | PF04695 | 0.256 |
LIG_PTB_Apo_2 | 529 | 536 | PF02174 | 0.346 |
LIG_PTB_Phospho_1 | 529 | 535 | PF10480 | 0.342 |
LIG_SH2_CRK | 255 | 259 | PF00017 | 0.291 |
LIG_SH2_CRK | 363 | 367 | PF00017 | 0.272 |
LIG_SH2_GRB2like | 7 | 10 | PF00017 | 0.492 |
LIG_SH2_NCK_1 | 255 | 259 | PF00017 | 0.291 |
LIG_SH2_PTP2 | 415 | 418 | PF00017 | 0.291 |
LIG_SH2_STAP1 | 255 | 259 | PF00017 | 0.316 |
LIG_SH2_STAT5 | 227 | 230 | PF00017 | 0.272 |
LIG_SH2_STAT5 | 252 | 255 | PF00017 | 0.272 |
LIG_SH2_STAT5 | 363 | 366 | PF00017 | 0.272 |
LIG_SH2_STAT5 | 392 | 395 | PF00017 | 0.256 |
LIG_SH2_STAT5 | 415 | 418 | PF00017 | 0.291 |
LIG_SH2_STAT5 | 7 | 10 | PF00017 | 0.588 |
LIG_SH3_3 | 208 | 214 | PF00018 | 0.398 |
LIG_SH3_3 | 262 | 268 | PF00018 | 0.256 |
LIG_SH3_3 | 71 | 77 | PF00018 | 0.589 |
LIG_SUMO_SIM_anti_2 | 18 | 24 | PF11976 | 0.444 |
LIG_SUMO_SIM_anti_2 | 462 | 468 | PF11976 | 0.306 |
LIG_SUMO_SIM_par_1 | 18 | 24 | PF11976 | 0.515 |
LIG_TRAF2_1 | 274 | 277 | PF00917 | 0.350 |
LIG_TYR_ITIM | 253 | 258 | PF00017 | 0.291 |
LIG_TYR_ITIM | 413 | 418 | PF00017 | 0.291 |
LIG_UBA3_1 | 189 | 194 | PF00899 | 0.291 |
LIG_UBA3_1 | 436 | 444 | PF00899 | 0.402 |
LIG_WRC_WIRS_1 | 347 | 352 | PF05994 | 0.316 |
MOD_CK1_1 | 183 | 189 | PF00069 | 0.259 |
MOD_CK1_1 | 324 | 330 | PF00069 | 0.256 |
MOD_CK1_1 | 506 | 512 | PF00069 | 0.513 |
MOD_CK2_1 | 398 | 404 | PF00069 | 0.443 |
MOD_CK2_1 | 76 | 82 | PF00069 | 0.449 |
MOD_CK2_1 | 84 | 90 | PF00069 | 0.455 |
MOD_Cter_Amidation | 199 | 202 | PF01082 | 0.321 |
MOD_Cter_Amidation | 497 | 500 | PF01082 | 0.492 |
MOD_GlcNHglycan | 118 | 121 | PF01048 | 0.332 |
MOD_GlcNHglycan | 182 | 185 | PF01048 | 0.259 |
MOD_GlcNHglycan | 262 | 265 | PF01048 | 0.256 |
MOD_GlcNHglycan | 368 | 371 | PF01048 | 0.297 |
MOD_GlcNHglycan | 505 | 509 | PF01048 | 0.514 |
MOD_GSK3_1 | 179 | 186 | PF00069 | 0.262 |
MOD_GSK3_1 | 362 | 369 | PF00069 | 0.270 |
MOD_GSK3_1 | 398 | 405 | PF00069 | 0.353 |
MOD_GSK3_1 | 461 | 468 | PF00069 | 0.321 |
MOD_GSK3_1 | 506 | 513 | PF00069 | 0.446 |
MOD_NEK2_1 | 140 | 145 | PF00069 | 0.271 |
MOD_NEK2_1 | 151 | 156 | PF00069 | 0.269 |
MOD_NEK2_1 | 238 | 243 | PF00069 | 0.398 |
MOD_NEK2_1 | 303 | 308 | PF00069 | 0.398 |
MOD_NEK2_1 | 427 | 432 | PF00069 | 0.378 |
MOD_NEK2_1 | 459 | 464 | PF00069 | 0.300 |
MOD_NEK2_1 | 503 | 508 | PF00069 | 0.585 |
MOD_NEK2_1 | 510 | 515 | PF00069 | 0.521 |
MOD_NEK2_1 | 530 | 535 | PF00069 | 0.491 |
MOD_NEK2_2 | 422 | 427 | PF00069 | 0.272 |
MOD_PIKK_1 | 100 | 106 | PF00454 | 0.456 |
MOD_PIKK_1 | 15 | 21 | PF00454 | 0.449 |
MOD_PIKK_1 | 2 | 8 | PF00454 | 0.511 |
MOD_PKA_2 | 200 | 206 | PF00069 | 0.327 |
MOD_PKA_2 | 402 | 408 | PF00069 | 0.366 |
MOD_PKA_2 | 41 | 47 | PF00069 | 0.479 |
MOD_PKB_1 | 316 | 324 | PF00069 | 0.350 |
MOD_Plk_1 | 109 | 115 | PF00069 | 0.431 |
MOD_Plk_1 | 518 | 524 | PF00069 | 0.363 |
MOD_Plk_4 | 160 | 166 | PF00069 | 0.294 |
MOD_Plk_4 | 185 | 191 | PF00069 | 0.272 |
MOD_Plk_4 | 207 | 213 | PF00069 | 0.266 |
MOD_Plk_4 | 336 | 342 | PF00069 | 0.257 |
MOD_Plk_4 | 422 | 428 | PF00069 | 0.272 |
MOD_Plk_4 | 461 | 467 | PF00069 | 0.287 |
MOD_Plk_4 | 483 | 489 | PF00069 | 0.475 |
MOD_Plk_4 | 506 | 512 | PF00069 | 0.428 |
MOD_Plk_4 | 530 | 536 | PF00069 | 0.485 |
MOD_ProDKin_1 | 13 | 19 | PF00069 | 0.506 |
MOD_ProDKin_1 | 362 | 368 | PF00069 | 0.272 |
MOD_ProDKin_1 | 465 | 471 | PF00069 | 0.404 |
MOD_SUMO_rev_2 | 441 | 445 | PF00179 | 0.450 |
MOD_SUMO_rev_2 | 478 | 483 | PF00179 | 0.456 |
MOD_SUMO_rev_2 | 491 | 501 | PF00179 | 0.405 |
MOD_SUMO_rev_2 | 78 | 86 | PF00179 | 0.429 |
TRG_DiLeu_BaEn_1 | 490 | 495 | PF01217 | 0.490 |
TRG_DiLeu_BaEn_1 | 97 | 102 | PF01217 | 0.417 |
TRG_ENDOCYTIC_2 | 227 | 230 | PF00928 | 0.256 |
TRG_ENDOCYTIC_2 | 255 | 258 | PF00928 | 0.274 |
TRG_ENDOCYTIC_2 | 415 | 418 | PF00928 | 0.291 |
TRG_ENDOCYTIC_2 | 48 | 51 | PF00928 | 0.428 |
TRG_ER_diArg_1 | 315 | 318 | PF00400 | 0.350 |
TRG_NES_CRM1_1 | 100 | 114 | PF08389 | 0.486 |
TRG_NES_CRM1_1 | 435 | 447 | PF08389 | 0.200 |
TRG_Pf-PMV_PEXEL_1 | 475 | 479 | PF00026 | 0.367 |
Protein | Taxonomy | Sequence identity | Coverage |
---|---|---|---|
A0A0N1IBN8 | Leptomonas seymouri | 76% | 99% |
A0A0S4JRW4 | Bodo saltans | 53% | 99% |
A0A1X0P362 | Trypanosomatidae | 65% | 100% |
A0A3Q8IS31 | Leishmania donovani | 94% | 100% |
A0A3R7KL89 | Trypanosoma rangeli | 63% | 100% |
A0B9M9 | Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) | 27% | 100% |
A4HIG7 | Leishmania braziliensis | 87% | 100% |
A4I5R3 | Leishmania infantum | 94% | 100% |
A6URB4 | Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) | 26% | 100% |
C9ZR31 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 63% | 100% |
O95470 | Homo sapiens | 37% | 95% |
P54767 | Solanum lycopersicum | 25% | 100% |
Q05567 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 37% | 91% |
Q12VA2 | Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M) | 27% | 100% |
Q2NHY7 | Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3) | 26% | 100% |
Q42472 | Arabidopsis thaliana | 24% | 100% |
Q46DU3 | Methanosarcina barkeri (strain Fusaro / DSM 804) | 29% | 100% |
Q4Q758 | Leishmania major | 91% | 100% |
Q52RG7 | Oryza sativa subsp. japonica | 40% | 100% |
Q54RV9 | Dictyostelium discoideum | 37% | 100% |
Q5R4G0 | Pongo abelii | 37% | 95% |
Q5WUR6 | Legionella pneumophila (strain Lens) | 33% | 89% |
Q5X3A8 | Legionella pneumophila (strain Paris) | 33% | 89% |
Q5ZTI6 | Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) | 32% | 89% |
Q8CHN6 | Rattus norvegicus | 39% | 95% |
Q8R0X7 | Mus musculus | 39% | 95% |
Q8U1P6 | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | 27% | 100% |
Q9C509 | Arabidopsis thaliana | 41% | 99% |
Q9UZD5 | Pyrococcus abyssi (strain GE5 / Orsay) | 28% | 100% |
Q9V7Y2 | Drosophila melanogaster | 38% | 99% |
Q9Y194 | Caenorhabditis elegans | 37% | 97% |
Q9ZPS3 | Arabidopsis thaliana | 25% | 100% |
Q9ZPS4 | Arabidopsis thaliana | 25% | 100% |
V5AWV1 | Trypanosoma cruzi | 62% | 86% |