Conserved zinc-finger protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

zinc-finger protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B107_LEIMU

TriTrypDb:

LmxM.29.2340

Length:

1196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B107

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B107

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1034	1038	PF00656	0.519
CLV_C14_Caspase3-7	18	22	PF00656	0.532
CLV_C14_Caspase3-7	242	246	PF00656	0.483
CLV_C14_Caspase3-7	405	409	PF00656	0.704
CLV_C14_Caspase3-7	507	511	PF00656	0.699
CLV_C14_Caspase3-7	637	641	PF00656	0.715
CLV_C14_Caspase3-7	840	844	PF00656	0.628
CLV_C14_Caspase3-7	905	909	PF00656	0.632
CLV_C14_Caspase3-7	921	925	PF00656	0.660
CLV_NRD_NRD_1	182	184	PF00675	0.586
CLV_NRD_NRD_1	253	255	PF00675	0.556
CLV_NRD_NRD_1	415	417	PF00675	0.730
CLV_NRD_NRD_1	671	673	PF00675	0.548
CLV_NRD_NRD_1	851	853	PF00675	0.695
CLV_NRD_NRD_1	88	90	PF00675	0.514
CLV_NRD_NRD_1	890	892	PF00675	0.675
CLV_NRD_NRD_1	98	100	PF00675	0.431
CLV_PCSK_FUR_1	185	189	PF00082	0.611
CLV_PCSK_FUR_1	384	388	PF00082	0.532
CLV_PCSK_KEX2_1	184	186	PF00082	0.588
CLV_PCSK_KEX2_1	187	189	PF00082	0.600
CLV_PCSK_KEX2_1	253	255	PF00082	0.405
CLV_PCSK_KEX2_1	386	388	PF00082	0.551
CLV_PCSK_KEX2_1	414	416	PF00082	0.734
CLV_PCSK_KEX2_1	671	673	PF00082	0.558
CLV_PCSK_KEX2_1	851	853	PF00082	0.695
CLV_PCSK_KEX2_1	88	90	PF00082	0.530
CLV_PCSK_KEX2_1	890	892	PF00082	0.675
CLV_PCSK_KEX2_1	98	100	PF00082	0.447
CLV_PCSK_PC1ET2_1	184	186	PF00082	0.588
CLV_PCSK_PC1ET2_1	187	189	PF00082	0.600
CLV_PCSK_PC1ET2_1	386	388	PF00082	0.533
CLV_PCSK_PC7_1	183	189	PF00082	0.608
CLV_PCSK_SKI1_1	1154	1158	PF00082	0.537
CLV_PCSK_SKI1_1	1184	1188	PF00082	0.690
CLV_PCSK_SKI1_1	208	212	PF00082	0.562
CLV_PCSK_SKI1_1	34	38	PF00082	0.580
CLV_PCSK_SKI1_1	387	391	PF00082	0.672
CLV_PCSK_SKI1_1	630	634	PF00082	0.604
CLV_PCSK_SKI1_1	672	676	PF00082	0.655
CLV_Separin_Metazoa	328	332	PF03568	0.523
DEG_Nend_UBRbox_1	1	4	PF02207	0.491
DEG_SPOP_SBC_1	219	223	PF00917	0.634
DOC_CKS1_1	428	433	PF01111	0.721
DOC_CKS1_1	520	525	PF01111	0.604
DOC_MAPK_gen_1	253	261	PF00069	0.530
DOC_MAPK_gen_1	384	392	PF00069	0.668
DOC_MAPK_gen_1	719	726	PF00069	0.668
DOC_MAPK_gen_1	732	741	PF00069	0.571
DOC_MAPK_MEF2A_6	254	263	PF00069	0.526
DOC_MAPK_MEF2A_6	826	833	PF00069	0.704
DOC_PP2B_LxvP_1	500	503	PF13499	0.666
DOC_PP4_FxxP_1	520	523	PF00568	0.560
DOC_USP7_MATH_1	1075	1079	PF00917	0.566
DOC_USP7_MATH_1	1097	1101	PF00917	0.598
DOC_USP7_MATH_1	177	181	PF00917	0.541
DOC_USP7_MATH_1	196	200	PF00917	0.433
DOC_USP7_MATH_1	220	224	PF00917	0.671
DOC_USP7_MATH_1	243	247	PF00917	0.488
DOC_USP7_MATH_1	286	290	PF00917	0.761
DOC_USP7_MATH_1	299	303	PF00917	0.647
DOC_USP7_MATH_1	342	346	PF00917	0.507
DOC_USP7_MATH_1	463	467	PF00917	0.619
DOC_USP7_MATH_1	476	480	PF00917	0.635
DOC_USP7_MATH_1	494	498	PF00917	0.524
DOC_USP7_MATH_1	514	518	PF00917	0.612
DOC_USP7_MATH_1	643	647	PF00917	0.597
DOC_USP7_MATH_1	662	666	PF00917	0.567
DOC_USP7_MATH_1	761	765	PF00917	0.665
DOC_USP7_MATH_1	778	782	PF00917	0.575
DOC_USP7_MATH_1	786	790	PF00917	0.579
DOC_USP7_MATH_1	809	813	PF00917	0.665
DOC_USP7_UBL2_3	1189	1193	PF12436	0.566
DOC_WW_Pin1_4	1007	1012	PF00397	0.735
DOC_WW_Pin1_4	1019	1024	PF00397	0.591
DOC_WW_Pin1_4	1086	1091	PF00397	0.681
DOC_WW_Pin1_4	134	139	PF00397	0.660
DOC_WW_Pin1_4	171	176	PF00397	0.357
DOC_WW_Pin1_4	424	429	PF00397	0.726
DOC_WW_Pin1_4	465	470	PF00397	0.685
DOC_WW_Pin1_4	490	495	PF00397	0.694
DOC_WW_Pin1_4	519	524	PF00397	0.610
DOC_WW_Pin1_4	639	644	PF00397	0.706
DOC_WW_Pin1_4	763	768	PF00397	0.617
DOC_WW_Pin1_4	773	778	PF00397	0.557
DOC_WW_Pin1_4	861	866	PF00397	0.590
LIG_14-3-3_CanoR_1	1165	1175	PF00244	0.706
LIG_14-3-3_CanoR_1	185	195	PF00244	0.498
LIG_14-3-3_CanoR_1	224	228	PF00244	0.523
LIG_14-3-3_CanoR_1	387	393	PF00244	0.674
LIG_14-3-3_CanoR_1	601	606	PF00244	0.529
LIG_14-3-3_CanoR_1	719	726	PF00244	0.668
LIG_14-3-3_CanoR_1	808	814	PF00244	0.670
LIG_14-3-3_CanoR_1	869	873	PF00244	0.620
LIG_14-3-3_CanoR_1	879	889	PF00244	0.552
LIG_14-3-3_CanoR_1	994	999	PF00244	0.711
LIG_Actin_WH2_2	318	333	PF00022	0.595
LIG_APCC_ABBA_1	323	328	PF00400	0.541
LIG_BIR_III_2	640	644	PF00653	0.712
LIG_BIR_III_4	935	939	PF00653	0.559
LIG_BRCT_BRCA1_1	516	520	PF00533	0.610
LIG_BRCT_BRCA1_1	643	647	PF00533	0.529
LIG_DLG_GKlike_1	994	1001	PF00625	0.533
LIG_EVH1_2	530	534	PF00568	0.595
LIG_FHA_1	214	220	PF00498	0.526
LIG_FHA_1	301	307	PF00498	0.560
LIG_FHA_1	563	569	PF00498	0.734
LIG_FHA_1	701	707	PF00498	0.547
LIG_FHA_1	822	828	PF00498	0.517
LIG_FHA_1	92	98	PF00498	0.639
LIG_FHA_2	1020	1026	PF00498	0.553
LIG_FHA_2	1045	1051	PF00498	0.679
LIG_FHA_2	1097	1103	PF00498	0.665
LIG_FHA_2	263	269	PF00498	0.392
LIG_FHA_2	330	336	PF00498	0.524
LIG_FHA_2	442	448	PF00498	0.551
LIG_FHA_2	470	476	PF00498	0.579
LIG_FHA_2	635	641	PF00498	0.688
LIG_FHA_2	692	698	PF00498	0.658
LIG_FHA_2	855	861	PF00498	0.570
LIG_FHA_2	935	941	PF00498	0.692
LIG_LIR_Apic_2	517	523	PF02991	0.595
LIG_LIR_Apic_2	525	531	PF02991	0.620
LIG_LIR_Gen_1	106	114	PF02991	0.386
LIG_LIR_Gen_1	13	24	PF02991	0.532
LIG_LIR_Gen_1	189	200	PF02991	0.455
LIG_LIR_Gen_1	997	1003	PF02991	0.530
LIG_LIR_Nem_3	1024	1029	PF02991	0.795
LIG_LIR_Nem_3	106	111	PF02991	0.389
LIG_LIR_Nem_3	13	19	PF02991	0.541
LIG_LIR_Nem_3	533	537	PF02991	0.631
LIG_LIR_Nem_3	75	81	PF02991	0.476
LIG_LIR_Nem_3	946	952	PF02991	0.669
LIG_LIR_Nem_3	997	1001	PF02991	0.637
LIG_MYND_3	914	918	PF01753	0.557
LIG_SH2_CRK	365	369	PF00017	0.516
LIG_SH2_CRK	528	532	PF00017	0.593
LIG_SH2_CRK	998	1002	PF00017	0.539
LIG_SH2_NCK_1	1093	1097	PF00017	0.531
LIG_SH2_NCK_1	365	369	PF00017	0.516
LIG_SH2_NCK_1	602	606	PF00017	0.527
LIG_SH2_STAP1	1029	1033	PF00017	0.702
LIG_SH2_STAP1	1093	1097	PF00017	0.531
LIG_SH2_STAP1	192	196	PF00017	0.463
LIG_SH2_STAP1	910	914	PF00017	0.735
LIG_SH2_STAP1	968	972	PF00017	0.523
LIG_SH2_STAP1	974	978	PF00017	0.527
LIG_SH2_STAT3	121	124	PF00017	0.531
LIG_SH2_STAT5	1029	1032	PF00017	0.700
LIG_SH2_STAT5	1093	1096	PF00017	0.532
LIG_SH2_STAT5	578	581	PF00017	0.650
LIG_SH2_STAT5	78	81	PF00017	0.540
LIG_SH3_2	398	403	PF14604	0.543
LIG_SH3_2	527	532	PF14604	0.590
LIG_SH3_3	377	383	PF00018	0.529
LIG_SH3_3	395	401	PF00018	0.519
LIG_SH3_3	425	431	PF00018	0.705
LIG_SH3_3	46	52	PF00018	0.553
LIG_SH3_3	524	530	PF00018	0.596
LIG_SH3_3	739	745	PF00018	0.626
LIG_SH3_3	799	805	PF00018	0.715
LIG_SH3_3	832	838	PF00018	0.586
LIG_SH3_3	859	865	PF00018	0.561
LIG_SH3_3	909	915	PF00018	0.686
LIG_SH3_3	927	933	PF00018	0.549
LIG_SH3_CIN85_PxpxPR_1	379	384	PF14604	0.651
LIG_SUMO_SIM_par_1	109	116	PF11976	0.488
LIG_SUMO_SIM_par_1	421	427	PF11976	0.728
LIG_TRAF2_1	1047	1050	PF00917	0.731
LIG_TRAF2_1	107	110	PF00917	0.402
LIG_TRAF2_1	372	375	PF00917	0.545
LIG_TRAF2_1	937	940	PF00917	0.666
LIG_WRC_WIRS_1	633	638	PF05994	0.603
LIG_WW_3	529	533	PF00397	0.593
MOD_CK1_1	1021	1027	PF00069	0.629
MOD_CK1_1	1169	1175	PF00069	0.681
MOD_CK1_1	137	143	PF00069	0.685
MOD_CK1_1	153	159	PF00069	0.482
MOD_CK1_1	223	229	PF00069	0.522
MOD_CK1_1	422	428	PF00069	0.680
MOD_CK1_1	474	480	PF00069	0.691
MOD_CK1_1	495	501	PF00069	0.679
MOD_CK1_1	535	541	PF00069	0.651
MOD_CK1_1	572	578	PF00069	0.591
MOD_CK1_1	612	618	PF00069	0.637
MOD_CK1_1	691	697	PF00069	0.645
MOD_CK1_1	797	803	PF00069	0.726
MOD_CK1_1	822	828	PF00069	0.541
MOD_CK1_1	882	888	PF00069	0.590
MOD_CK1_1	897	903	PF00069	0.667
MOD_CK2_1	103	109	PF00069	0.405
MOD_CK2_1	1033	1039	PF00069	0.616
MOD_CK2_1	1044	1050	PF00069	0.613
MOD_CK2_1	1075	1081	PF00069	0.567
MOD_CK2_1	1096	1102	PF00069	0.680
MOD_CK2_1	262	268	PF00069	0.447
MOD_CK2_1	286	292	PF00069	0.689
MOD_CK2_1	329	335	PF00069	0.476
MOD_CK2_1	399	405	PF00069	0.680
MOD_CK2_1	415	421	PF00069	0.613
MOD_CK2_1	441	447	PF00069	0.553
MOD_CK2_1	454	460	PF00069	0.584
MOD_CK2_1	653	659	PF00069	0.651
MOD_CK2_1	691	697	PF00069	0.681
MOD_CK2_1	854	860	PF00069	0.567
MOD_CK2_1	889	895	PF00069	0.684
MOD_CK2_1	934	940	PF00069	0.670
MOD_Cter_Amidation	1179	1182	PF01082	0.519
MOD_DYRK1A_RPxSP_1	134	138	PF00069	0.535
MOD_GlcNHglycan	101	106	PF01048	0.398
MOD_GlcNHglycan	1068	1071	PF01048	0.684
MOD_GlcNHglycan	1099	1102	PF01048	0.708
MOD_GlcNHglycan	1131	1134	PF01048	0.687
MOD_GlcNHglycan	1158	1162	PF01048	0.542
MOD_GlcNHglycan	198	201	PF01048	0.619
MOD_GlcNHglycan	227	230	PF01048	0.617
MOD_GlcNHglycan	288	291	PF01048	0.678
MOD_GlcNHglycan	31	34	PF01048	0.415
MOD_GlcNHglycan	340	343	PF01048	0.602
MOD_GlcNHglycan	346	349	PF01048	0.621
MOD_GlcNHglycan	352	355	PF01048	0.584
MOD_GlcNHglycan	465	468	PF01048	0.645
MOD_GlcNHglycan	475	479	PF01048	0.662
MOD_GlcNHglycan	497	500	PF01048	0.730
MOD_GlcNHglycan	524	527	PF01048	0.606
MOD_GlcNHglycan	533	537	PF01048	0.567
MOD_GlcNHglycan	572	575	PF01048	0.661
MOD_GlcNHglycan	585	588	PF01048	0.600
MOD_GlcNHglycan	592	595	PF01048	0.541
MOD_GlcNHglycan	597	600	PF01048	0.622
MOD_GlcNHglycan	603	606	PF01048	0.556
MOD_GlcNHglycan	614	617	PF01048	0.526
MOD_GlcNHglycan	664	667	PF01048	0.631
MOD_GlcNHglycan	690	693	PF01048	0.596
MOD_GlcNHglycan	752	755	PF01048	0.660
MOD_GlcNHglycan	763	766	PF01048	0.555
MOD_GlcNHglycan	780	783	PF01048	0.574
MOD_GlcNHglycan	788	791	PF01048	0.592
MOD_GlcNHglycan	891	894	PF01048	0.620
MOD_GSK3_1	1015	1022	PF00069	0.635
MOD_GSK3_1	1027	1034	PF00069	0.680
MOD_GSK3_1	1062	1069	PF00069	0.655
MOD_GSK3_1	1071	1078	PF00069	0.598
MOD_GSK3_1	1165	1172	PF00069	0.726
MOD_GSK3_1	196	203	PF00069	0.634
MOD_GSK3_1	214	221	PF00069	0.520
MOD_GSK3_1	338	345	PF00069	0.440
MOD_GSK3_1	415	422	PF00069	0.685
MOD_GSK3_1	465	472	PF00069	0.652
MOD_GSK3_1	490	497	PF00069	0.678
MOD_GSK3_1	608	615	PF00069	0.629
MOD_GSK3_1	635	642	PF00069	0.637
MOD_GSK3_1	687	694	PF00069	0.629
MOD_GSK3_1	727	734	PF00069	0.576
MOD_GSK3_1	769	776	PF00069	0.590
MOD_GSK3_1	809	816	PF00069	0.719
MOD_GSK3_1	875	882	PF00069	0.674
MOD_GSK3_1	897	904	PF00069	0.599
MOD_GSK3_1	990	997	PF00069	0.657
MOD_N-GLC_1	150	155	PF02516	0.491
MOD_NEK2_1	1091	1096	PF00069	0.530
MOD_NEK2_1	1118	1123	PF00069	0.654
MOD_NEK2_1	1171	1176	PF00069	0.563
MOD_NEK2_1	213	218	PF00069	0.531
MOD_NEK2_1	329	334	PF00069	0.574
MOD_NEK2_1	504	509	PF00069	0.591
MOD_NEK2_1	546	551	PF00069	0.681
MOD_NEK2_1	653	658	PF00069	0.649
MOD_NEK2_1	72	77	PF00069	0.453
MOD_NEK2_1	794	799	PF00069	0.556
MOD_NEK2_1	813	818	PF00069	0.644
MOD_NEK2_1	868	873	PF00069	0.645
MOD_NEK2_1	875	880	PF00069	0.644
MOD_NEK2_2	200	205	PF00069	0.590
MOD_NEK2_2	700	705	PF00069	0.574
MOD_PIKK_1	1009	1015	PF00454	0.678
MOD_PIKK_1	1062	1068	PF00454	0.611
MOD_PIKK_1	1166	1172	PF00454	0.709
MOD_PIKK_1	214	220	PF00454	0.591
MOD_PIKK_1	557	563	PF00454	0.656
MOD_PIKK_1	572	578	PF00454	0.578
MOD_PIKK_1	691	697	PF00454	0.608
MOD_PIKK_1	706	712	PF00454	0.586
MOD_PIKK_1	719	725	PF00454	0.669
MOD_PIKK_1	727	733	PF00454	0.650
MOD_PIKK_1	770	776	PF00454	0.637
MOD_PIKK_1	882	888	PF00454	0.557
MOD_PK_1	415	421	PF00069	0.663
MOD_PKA_1	415	421	PF00069	0.727
MOD_PKA_2	1097	1103	PF00069	0.600
MOD_PKA_2	1129	1135	PF00069	0.681
MOD_PKA_2	153	159	PF00069	0.484
MOD_PKA_2	223	229	PF00069	0.522
MOD_PKA_2	415	421	PF00069	0.727
MOD_PKA_2	600	606	PF00069	0.530
MOD_PKA_2	687	693	PF00069	0.684
MOD_PKA_2	731	737	PF00069	0.545
MOD_PKA_2	794	800	PF00069	0.705
MOD_PKA_2	868	874	PF00069	0.617
MOD_PKA_2	889	895	PF00069	0.642
MOD_Plk_1	1024	1030	PF00069	0.690
MOD_Plk_1	1157	1163	PF00069	0.544
MOD_Plk_1	37	43	PF00069	0.569
MOD_Plk_1	990	996	PF00069	0.589
MOD_Plk_2-3	908	914	PF00069	0.623
MOD_Plk_4	15	21	PF00069	0.612
MOD_Plk_4	235	241	PF00069	0.654
MOD_Plk_4	262	268	PF00069	0.436
MOD_Plk_4	419	425	PF00069	0.727
MOD_Plk_4	868	874	PF00069	0.540
MOD_Plk_4	963	969	PF00069	0.518
MOD_ProDKin_1	1007	1013	PF00069	0.738
MOD_ProDKin_1	1019	1025	PF00069	0.588
MOD_ProDKin_1	1086	1092	PF00069	0.679
MOD_ProDKin_1	134	140	PF00069	0.664
MOD_ProDKin_1	171	177	PF00069	0.357
MOD_ProDKin_1	424	430	PF00069	0.725
MOD_ProDKin_1	465	471	PF00069	0.684
MOD_ProDKin_1	490	496	PF00069	0.688
MOD_ProDKin_1	519	525	PF00069	0.611
MOD_ProDKin_1	639	645	PF00069	0.701
MOD_ProDKin_1	763	769	PF00069	0.618
MOD_ProDKin_1	773	779	PF00069	0.557
MOD_ProDKin_1	861	867	PF00069	0.590
MOD_SUMO_for_1	1125	1128	PF00179	0.541
MOD_SUMO_rev_2	29	39	PF00179	0.586
MOD_SUMO_rev_2	475	485	PF00179	0.657
MOD_SUMO_rev_2	894	903	PF00179	0.737
TRG_DiLeu_BaEn_1	318	323	PF01217	0.617
TRG_DiLeu_BaEn_4	109	115	PF01217	0.441
TRG_DiLeu_BaEn_4	318	324	PF01217	0.613
TRG_DiLeu_BaLyEn_6	764	769	PF01217	0.554
TRG_ENDOCYTIC_2	192	195	PF00928	0.466
TRG_ENDOCYTIC_2	998	1001	PF00928	0.539
TRG_ER_diArg_1	182	185	PF00400	0.592
TRG_ER_diArg_1	252	254	PF00400	0.411
TRG_ER_diArg_1	414	416	PF00400	0.732
TRG_ER_diArg_1	5	8	PF00400	0.566
TRG_ER_diArg_1	889	891	PF00400	0.619
TRG_ER_diArg_1	97	99	PF00400	0.546
TRG_ER_diArg_1	981	984	PF00400	0.541
TRG_ER_diLys_1	1193	1196	PF00400	0.670
TRG_NES_CRM1_1	109	124	PF08389	0.430
TRG_NLS_MonoExtC_3	182	187	PF00514	0.587
TRG_NLS_MonoExtN_4	1117	1123	PF00514	0.590
TRG_NLS_MonoExtN_4	183	188	PF00514	0.603
TRG_Pf-PMV_PEXEL_1	126	130	PF00026	0.524
TRG_Pf-PMV_PEXEL_1	250	255	PF00026	0.481
TRG_Pf-PMV_PEXEL_1	66	70	PF00026	0.478

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IF13	Leishmania donovani	73%	100%
A4HIG6	Leishmania braziliensis	49%	98%
Q4Q759	Leishmania major	75%	100%