N-acetyltransferase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B106_LEIMU

TriTrypDb:

LmxM.29.2330

Length:

349

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B106

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B106

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	96	100	PF00656	0.603
CLV_NRD_NRD_1	255	257	PF00675	0.617
CLV_NRD_NRD_1	82	84	PF00675	0.414
CLV_PCSK_SKI1_1	109	113	PF00082	0.547
DEG_SPOP_SBC_1	35	39	PF00917	0.671
DOC_MAPK_gen_1	107	116	PF00069	0.546
DOC_MAPK_gen_1	300	307	PF00069	0.575
DOC_PP1_RVXF_1	107	114	PF00149	0.530
DOC_PP1_RVXF_1	130	137	PF00149	0.478
DOC_USP7_MATH_1	188	192	PF00917	0.522
DOC_USP7_MATH_1	246	250	PF00917	0.360
DOC_USP7_MATH_1	5	9	PF00917	0.389
DOC_USP7_MATH_1	86	90	PF00917	0.657
DOC_WW_Pin1_4	27	32	PF00397	0.639
DOC_WW_Pin1_4	291	296	PF00397	0.721
DOC_WW_Pin1_4	65	70	PF00397	0.649
LIG_14-3-3_CanoR_1	107	112	PF00244	0.559
LIG_14-3-3_CanoR_1	115	120	PF00244	0.423
LIG_14-3-3_CanoR_1	20	28	PF00244	0.574
LIG_APCC_ABBA_1	120	125	PF00400	0.297
LIG_APCC_ABBA_1	148	153	PF00400	0.411
LIG_APCC_ABBA_1	59	64	PF00400	0.538
LIG_BRCT_BRCA1_1	109	113	PF00533	0.640
LIG_FHA_1	124	130	PF00498	0.417
LIG_FHA_1	170	176	PF00498	0.483
LIG_FHA_1	35	41	PF00498	0.644
LIG_FHA_1	54	60	PF00498	0.501
LIG_FHA_2	286	292	PF00498	0.504
LIG_LIR_Gen_1	102	113	PF02991	0.521
LIG_LIR_Gen_1	118	125	PF02991	0.482
LIG_LIR_Gen_1	303	312	PF02991	0.752
LIG_LIR_Nem_3	102	108	PF02991	0.478
LIG_LIR_Nem_3	110	116	PF02991	0.513
LIG_LIR_Nem_3	118	122	PF02991	0.461
LIG_LIR_Nem_3	303	307	PF02991	0.635
LIG_MLH1_MIPbox_1	109	113	PF16413	0.640
LIG_NRBOX	202	208	PF00104	0.492
LIG_REV1ctd_RIR_1	110	119	PF16727	0.600
LIG_SH2_STAP1	337	341	PF00017	0.653
LIG_SH2_STAT5	174	177	PF00017	0.492
LIG_SH2_STAT5	337	340	PF00017	0.605
LIG_SH2_STAT5	62	65	PF00017	0.482
LIG_SH2_STAT5	74	77	PF00017	0.483
LIG_SH3_3	28	34	PF00018	0.650
LIG_TRAF2_1	69	72	PF00917	0.487
LIG_TRAF2_2	137	142	PF00917	0.557
LIG_WRC_WIRS_1	116	121	PF05994	0.558
MOD_CDC14_SPxK_1	30	33	PF00782	0.658
MOD_CDK_SPxK_1	27	33	PF00069	0.639
MOD_CK1_1	89	95	PF00069	0.576
MOD_CK2_1	285	291	PF00069	0.575
MOD_CK2_1	49	55	PF00069	0.433
MOD_GlcNHglycan	190	193	PF01048	0.659
MOD_GlcNHglycan	248	251	PF01048	0.356
MOD_GlcNHglycan	307	310	PF01048	0.549
MOD_GlcNHglycan	7	10	PF01048	0.421
MOD_GSK3_1	244	251	PF00069	0.649
MOD_GSK3_1	277	284	PF00069	0.581
MOD_GSK3_1	49	56	PF00069	0.536
MOD_N-GLC_1	244	249	PF02516	0.362
MOD_N-GLC_1	285	290	PF02516	0.510
MOD_NEK2_1	198	203	PF00069	0.461
MOD_NEK2_1	319	324	PF00069	0.649
MOD_NEK2_2	169	174	PF00069	0.325
MOD_NEK2_2	62	67	PF00069	0.530
MOD_PIKK_1	190	196	PF00454	0.457
MOD_PK_1	107	113	PF00069	0.554
MOD_PKA_2	89	95	PF00069	0.542
MOD_Plk_1	281	287	PF00069	0.510
MOD_Plk_1	35	41	PF00069	0.658
MOD_Plk_4	107	113	PF00069	0.618
MOD_Plk_4	169	175	PF00069	0.480
MOD_Plk_4	36	42	PF00069	0.656
MOD_ProDKin_1	27	33	PF00069	0.639
MOD_ProDKin_1	291	297	PF00069	0.721
MOD_ProDKin_1	65	71	PF00069	0.643
MOD_SUMO_rev_2	259	265	PF00179	0.566
MOD_SUMO_rev_2	267	275	PF00179	0.651
MOD_SUMO_rev_2	8	17	PF00179	0.578
TRG_DiLeu_BaEn_1	36	41	PF01217	0.579
TRG_ER_diArg_1	114	117	PF00400	0.419

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8P9	Leptomonas seymouri	48%	100%
A0A3Q8II20	Leishmania donovani	82%	100%
A4HIG5	Leishmania braziliensis	64%	100%
A4I5R1	Leishmania infantum	82%	100%
Q4Q760	Leishmania major	78%	98%