Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B0Z6_LEIMU

TriTrypDb:

LmxM.29.2230

Length:

250

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0Z6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0Z6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	3	5	PF00675	0.503
CLV_NRD_NRD_1	44	46	PF00675	0.563
CLV_PCSK_KEX2_1	2	4	PF00082	0.552
CLV_PCSK_KEX2_1	44	46	PF00082	0.520
CLV_PCSK_SKI1_1	183	187	PF00082	0.411
CLV_PCSK_SKI1_1	4	8	PF00082	0.595
DEG_APCC_KENBOX_2	31	35	PF00400	0.428
DEG_Nend_UBRbox_1	1	4	PF02207	0.593
DOC_CYCLIN_RxL_1	1	10	PF00134	0.600
DOC_MAPK_gen_1	2	8	PF00069	0.548
DOC_PP1_RVXF_1	42	49	PF00149	0.500
DOC_PP2B_LxvP_1	231	234	PF13499	0.520
DOC_USP7_MATH_1	159	163	PF00917	0.679
DOC_USP7_UBL2_3	28	32	PF12436	0.412
DOC_WW_Pin1_4	105	110	PF00397	0.696
DOC_WW_Pin1_4	124	129	PF00397	0.477
LIG_APCC_ABBA_1	36	41	PF00400	0.448
LIG_BRCT_BRCA1_1	162	166	PF00533	0.627
LIG_BRCT_BRCA1_1	70	74	PF00533	0.474
LIG_eIF4E_1	30	36	PF01652	0.557
LIG_FHA_1	8	14	PF00498	0.497
LIG_FHA_2	238	244	PF00498	0.436
LIG_FHA_2	90	96	PF00498	0.700
LIG_LIR_Apic_2	169	173	PF02991	0.409
LIG_LIR_Gen_1	15	24	PF02991	0.398
LIG_LIR_Gen_1	199	208	PF02991	0.602
LIG_LIR_Nem_3	139	144	PF02991	0.467
LIG_LIR_Nem_3	199	203	PF02991	0.535
LIG_LIR_Nem_3	60	66	PF02991	0.482
LIG_LYPXL_L_2	224	233	PF13949	0.449
LIG_MLH1_MIPbox_1	163	167	PF16413	0.599
LIG_PDZ_Class_2	245	250	PF00595	0.449
LIG_Pex14_2	166	170	PF04695	0.490
LIG_REV1ctd_RIR_1	139	147	PF16727	0.257
LIG_SH2_NCK_1	126	130	PF00017	0.440
LIG_SH2_STAT3	67	70	PF00017	0.397
LIG_SH2_STAT5	64	67	PF00017	0.399
LIG_SH3_3	107	113	PF00018	0.694
LIG_TRAF2_1	76	79	PF00917	0.545
LIG_WRC_WIRS_1	197	202	PF05994	0.562
LIG_WRC_WIRS_1	245	250	PF05994	0.573
LIG_WRC_WIRS_1	66	71	PF05994	0.389
MOD_CK1_1	127	133	PF00069	0.579
MOD_CK1_1	199	205	PF00069	0.530
MOD_CK1_1	85	91	PF00069	0.590
MOD_CK2_1	237	243	PF00069	0.473
MOD_GlcNHglycan	103	106	PF01048	0.450
MOD_GlcNHglycan	157	160	PF01048	0.651
MOD_GlcNHglycan	84	87	PF01048	0.806
MOD_GSK3_1	155	162	PF00069	0.652
MOD_GSK3_1	237	244	PF00069	0.430
MOD_GSK3_1	65	72	PF00069	0.465
MOD_GSK3_1	85	92	PF00069	0.669
MOD_GSK3_1	97	104	PF00069	0.693
MOD_N-GLC_1	159	164	PF02516	0.666
MOD_N-GLC_1	89	94	PF02516	0.646
MOD_NEK2_1	241	246	PF00069	0.492
MOD_NEK2_1	65	70	PF00069	0.417
MOD_NEK2_1	7	12	PF00069	0.575
MOD_PIKK_1	85	91	PF00454	0.665
MOD_Plk_1	237	243	PF00069	0.437
MOD_Plk_4	183	189	PF00069	0.573
MOD_Plk_4	199	205	PF00069	0.319
MOD_Plk_4	34	40	PF00069	0.419
MOD_ProDKin_1	105	111	PF00069	0.696
MOD_ProDKin_1	124	130	PF00069	0.466
MOD_SUMO_for_1	114	117	PF00179	0.732
TRG_DiLeu_BaEn_4	78	84	PF01217	0.575
TRG_ENDOCYTIC_2	63	66	PF00928	0.389
TRG_ER_diArg_1	1	4	PF00400	0.593
TRG_ER_diArg_1	44	47	PF00400	0.487
TRG_Pf-PMV_PEXEL_1	4	9	PF00026	0.566

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P919	Leptomonas seymouri	54%	100%
A0A0N1I9X1	Leptomonas seymouri	50%	100%
A0A0S4IR38	Bodo saltans	30%	98%
A0A3S7X3I9	Leishmania donovani	90%	100%
A4HIF5	Leishmania braziliensis	77%	100%
A4I5Q1	Leishmania infantum	89%	100%
Q4Q770	Leishmania major	88%	100%