Oligomerization domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Oligomerisation domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9B0Y5_LEIMU

TriTrypDb:

LmxM.29.2120

Length:

534

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

E9B0Y5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0Y5

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	3
GO:0006396	RNA processing	6	3
GO:0006725	cellular aromatic compound metabolic process	3	3
GO:0006807	nitrogen compound metabolic process	2	3
GO:0008152	metabolic process	1	3
GO:0009987	cellular process	1	3
GO:0016070	RNA metabolic process	5	3
GO:0031123	RNA 3'-end processing	7	3
GO:0034641	cellular nitrogen compound metabolic process	3	3
GO:0043170	macromolecule metabolic process	3	3
GO:0044237	cellular metabolic process	2	3
GO:0044238	primary metabolic process	2	3
GO:0046483	heterocycle metabolic process	3	3
GO:0071076	RNA 3' uridylation	8	3
GO:0071704	organic substance metabolic process	2	3
GO:0090304	nucleic acid metabolic process	4	3
GO:1901360	organic cyclic compound metabolic process	3	3

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	3
GO:0016740	transferase activity	2	3
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	3
GO:0016779	nucleotidyltransferase activity	4	3
GO:0050265	RNA uridylyltransferase activity	4	3
GO:0070569	uridylyltransferase activity	5	3
GO:0140098	catalytic activity, acting on RNA	3	3
GO:0140640	catalytic activity, acting on a nucleic acid	2	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	325	329	PF00656	0.672
CLV_C14_Caspase3-7	373	377	PF00656	0.585
CLV_MEL_PAP_1	128	134	PF00089	0.674
CLV_NRD_NRD_1	116	118	PF00675	0.673
CLV_NRD_NRD_1	195	197	PF00675	0.704
CLV_NRD_NRD_1	342	344	PF00675	0.704
CLV_NRD_NRD_1	381	383	PF00675	0.458
CLV_NRD_NRD_1	446	448	PF00675	0.549
CLV_NRD_NRD_1	478	480	PF00675	0.549
CLV_PCSK_KEX2_1	116	118	PF00082	0.673
CLV_PCSK_KEX2_1	195	197	PF00082	0.704
CLV_PCSK_KEX2_1	342	344	PF00082	0.704
CLV_PCSK_KEX2_1	381	383	PF00082	0.527
CLV_PCSK_KEX2_1	446	448	PF00082	0.549
CLV_PCSK_PC1ET2_1	446	448	PF00082	0.549
CLV_PCSK_PC7_1	191	197	PF00082	0.695
CLV_PCSK_SKI1_1	11	15	PF00082	0.675
CLV_PCSK_SKI1_1	195	199	PF00082	0.705
CLV_PCSK_SKI1_1	36	40	PF00082	0.539
CLV_PCSK_SKI1_1	501	505	PF00082	0.701
CLV_PCSK_SKI1_1	527	531	PF00082	0.613
DOC_CYCLIN_RxL_1	191	201	PF00134	0.699
DOC_CYCLIN_yCln2_LP_2	274	280	PF00134	0.697
DOC_MAPK_gen_1	270	278	PF00069	0.592
DOC_MAPK_gen_1	396	405	PF00069	0.549
DOC_MAPK_MEF2A_6	270	278	PF00069	0.627
DOC_MAPK_MEF2A_6	356	364	PF00069	0.531
DOC_MAPK_MEF2A_6	461	468	PF00069	0.549
DOC_PP1_RVXF_1	34	41	PF00149	0.539
DOC_PP2B_LxvP_1	274	277	PF13499	0.682
DOC_PP4_FxxP_1	190	193	PF00568	0.685
DOC_USP7_MATH_1	108	112	PF00917	0.670
DOC_USP7_MATH_1	242	246	PF00917	0.798
DOC_USP7_MATH_1	26	30	PF00917	0.620
DOC_USP7_MATH_1	309	313	PF00917	0.794
DOC_USP7_MATH_1	345	349	PF00917	0.779
DOC_USP7_UBL2_3	444	448	PF12436	0.549
DOC_WW_Pin1_4	148	153	PF00397	0.701
DOC_WW_Pin1_4	183	188	PF00397	0.676
DOC_WW_Pin1_4	240	245	PF00397	0.638
DOC_WW_Pin1_4	97	102	PF00397	0.670
LIG_14-3-3_CanoR_1	131	139	PF00244	0.735
LIG_14-3-3_CanoR_1	141	147	PF00244	0.709
LIG_14-3-3_CanoR_1	168	176	PF00244	0.663
LIG_14-3-3_CanoR_1	195	201	PF00244	0.815
LIG_14-3-3_CanoR_1	25	34	PF00244	0.621
LIG_14-3-3_CanoR_1	293	297	PF00244	0.583
LIG_14-3-3_CanoR_1	43	49	PF00244	0.440
LIG_14-3-3_CanoR_1	447	456	PF00244	0.384
LIG_14-3-3_CanoR_1	51	55	PF00244	0.594
LIG_14-3-3_CanoR_1	88	97	PF00244	0.657
LIG_Actin_WH2_2	27	45	PF00022	0.618
LIG_APCC_ABBA_1	155	160	PF00400	0.793
LIG_BIR_II_1	1	5	PF00653	0.695
LIG_CaM_IQ_9	430	446	PF13499	0.549
LIG_Clathr_ClatBox_1	361	365	PF01394	0.632
LIG_eIF4E_1	525	531	PF01652	0.616
LIG_FHA_1	149	155	PF00498	0.793
LIG_FHA_1	26	32	PF00498	0.617
LIG_FHA_1	314	320	PF00498	0.682
LIG_FHA_1	448	454	PF00498	0.549
LIG_FHA_1	508	514	PF00498	0.503
LIG_FHA_1	51	57	PF00498	0.685
LIG_FHA_1	89	95	PF00498	0.657
LIG_FHA_2	1	7	PF00498	0.693
LIG_FHA_2	332	338	PF00498	0.800
LIG_FHA_2	371	377	PF00498	0.572
LIG_FHA_2	74	80	PF00498	0.708
LIG_LIR_Gen_1	216	226	PF02991	0.580
LIG_LIR_Gen_1	354	364	PF02991	0.494
LIG_LIR_Gen_1	409	417	PF02991	0.425
LIG_LIR_Gen_1	451	462	PF02991	0.549
LIG_LIR_Nem_3	216	222	PF02991	0.580
LIG_LIR_Nem_3	413	417	PF02991	0.549
LIG_LIR_Nem_3	451	457	PF02991	0.379
LIG_Pex14_2	93	97	PF04695	0.656
LIG_REV1ctd_RIR_1	37	47	PF16727	0.629
LIG_SH2_CRK	271	275	PF00017	0.507
LIG_SH2_SRC	162	165	PF00017	0.791
LIG_SH2_STAP1	162	166	PF00017	0.675
LIG_SH2_STAT3	139	142	PF00017	0.685
LIG_SH2_STAT3	71	74	PF00017	0.805
LIG_SH2_STAT5	525	528	PF00017	0.534
LIG_SH2_STAT5	71	74	PF00017	0.758
LIG_SH3_2	83	88	PF14604	0.644
LIG_SH3_3	332	338	PF00018	0.684
LIG_SH3_3	80	86	PF00018	0.760
LIG_SH3_CIN85_PxpxPR_1	83	88	PF14604	0.644
LIG_SUMO_SIM_par_1	315	321	PF11976	0.679
LIG_TRAF2_1	2	5	PF00917	0.691
LIG_TRAF2_1	264	267	PF00917	0.703
LIG_TRAF2_1	298	301	PF00917	0.780
LIG_TRAF2_1	338	341	PF00917	0.814
LIG_UBA3_1	391	396	PF00899	0.549
LIG_WRC_WIRS_1	319	324	PF05994	0.681
LIG_WRC_WIRS_1	468	473	PF05994	0.549
LIG_WW_3	85	89	PF00397	0.641
MOD_CK1_1	107	113	PF00069	0.664
MOD_CK1_1	145	151	PF00069	0.800
MOD_CK1_1	167	173	PF00069	0.791
MOD_CK1_1	243	249	PF00069	0.790
MOD_CK1_1	406	412	PF00069	0.549
MOD_CK1_1	47	53	PF00069	0.723
MOD_CK1_1	73	79	PF00069	0.704
MOD_CK2_1	467	473	PF00069	0.549
MOD_CK2_1	73	79	PF00069	0.704
MOD_GlcNHglycan	106	109	PF01048	0.663
MOD_GlcNHglycan	147	150	PF01048	0.652
MOD_GlcNHglycan	245	248	PF01048	0.671
MOD_GlcNHglycan	28	31	PF01048	0.547
MOD_GlcNHglycan	311	314	PF01048	0.769
MOD_GSK3_1	104	111	PF00069	0.704
MOD_GSK3_1	167	174	PF00069	0.675
MOD_GSK3_1	196	203	PF00069	0.824
MOD_GSK3_1	309	316	PF00069	0.724
MOD_GSK3_1	318	325	PF00069	0.656
MOD_GSK3_1	403	410	PF00069	0.549
MOD_GSK3_1	416	423	PF00069	0.504
MOD_GSK3_1	69	76	PF00069	0.724
MOD_LATS_1	194	200	PF00433	0.822
MOD_N-GLC_1	313	318	PF02516	0.678
MOD_N-GLC_2	55	57	PF02516	0.800
MOD_NEK2_1	130	135	PF00069	0.651
MOD_NEK2_1	198	203	PF00069	0.814
MOD_NEK2_1	226	231	PF00069	0.639
MOD_NEK2_1	322	327	PF00069	0.679
MOD_NEK2_1	467	472	PF00069	0.549
MOD_NEK2_1	7	12	PF00069	0.677
MOD_NEK2_2	171	176	PF00069	0.678
MOD_OFUCOSY	57	63	PF10250	0.666
MOD_PIKK_1	229	235	PF00454	0.783
MOD_PIKK_1	70	76	PF00454	0.690
MOD_PK_1	196	202	PF00069	0.707
MOD_PKA_1	447	453	PF00069	0.549
MOD_PKA_2	130	136	PF00069	0.723
MOD_PKA_2	167	173	PF00069	0.698
MOD_PKA_2	24	30	PF00069	0.635
MOD_PKA_2	269	275	PF00069	0.671
MOD_PKA_2	292	298	PF00069	0.725
MOD_PKA_2	440	446	PF00069	0.418
MOD_PKA_2	50	56	PF00069	0.682
MOD_PKB_1	287	295	PF00069	0.717
MOD_Plk_1	313	319	PF00069	0.772
MOD_Plk_1	370	376	PF00069	0.556
MOD_Plk_1	473	479	PF00069	0.549
MOD_Plk_2-3	473	479	PF00069	0.549
MOD_Plk_4	150	156	PF00069	0.678
MOD_Plk_4	171	177	PF00069	0.679
MOD_Plk_4	292	298	PF00069	0.550
MOD_ProDKin_1	148	154	PF00069	0.701
MOD_ProDKin_1	183	189	PF00069	0.678
MOD_ProDKin_1	240	246	PF00069	0.637
MOD_ProDKin_1	97	103	PF00069	0.672
MOD_SUMO_rev_2	371	380	PF00179	0.685
MOD_SUMO_rev_2	383	388	PF00179	0.412
MOD_SUMO_rev_2	473	482	PF00179	0.549
TRG_ENDOCYTIC_2	166	169	PF00928	0.796
TRG_ENDOCYTIC_2	271	274	PF00928	0.497
TRG_ENDOCYTIC_2	414	417	PF00928	0.549
TRG_ER_diArg_1	116	118	PF00400	0.673
TRG_ER_diArg_1	195	197	PF00400	0.704
TRG_ER_diArg_1	202	205	PF00400	0.637
TRG_ER_diArg_1	273	276	PF00400	0.673
TRG_ER_diArg_1	342	344	PF00400	0.704
TRG_NES_CRM1_1	387	399	PF08389	0.549
TRG_NLS_MonoExtC_3	377	382	PF00514	0.678
TRG_NLS_MonoExtC_3	445	451	PF00514	0.549
TRG_NLS_MonoExtN_4	444	450	PF00514	0.549

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I5P1	Leishmania infantum	83%	100%