Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0X9_LEIMU

TriTrypDb:

LmxM.29.2065

Length:

313

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0X9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0X9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	12	14	PF00675	0.526
CLV_NRD_NRD_1	125	127	PF00675	0.693
CLV_NRD_NRD_1	154	156	PF00675	0.717
CLV_NRD_NRD_1	207	209	PF00675	0.612
CLV_NRD_NRD_1	226	228	PF00675	0.655
CLV_NRD_NRD_1	255	257	PF00675	0.683
CLV_NRD_NRD_1	292	294	PF00675	0.613
CLV_NRD_NRD_1	300	302	PF00675	0.547
CLV_NRD_NRD_1	70	72	PF00675	0.566
CLV_NRD_NRD_1	95	97	PF00675	0.619
CLV_PCSK_FUR_1	123	127	PF00082	0.698
CLV_PCSK_FUR_1	152	156	PF00082	0.620
CLV_PCSK_FUR_1	68	72	PF00082	0.668
CLV_PCSK_KEX2_1	12	14	PF00082	0.526
CLV_PCSK_KEX2_1	125	127	PF00082	0.643
CLV_PCSK_KEX2_1	154	156	PF00082	0.717
CLV_PCSK_KEX2_1	207	209	PF00082	0.588
CLV_PCSK_KEX2_1	226	228	PF00082	0.658
CLV_PCSK_KEX2_1	255	257	PF00082	0.683
CLV_PCSK_KEX2_1	292	294	PF00082	0.612
CLV_PCSK_KEX2_1	300	302	PF00082	0.545
CLV_PCSK_KEX2_1	70	72	PF00082	0.566
CLV_PCSK_KEX2_1	95	97	PF00082	0.618
CLV_PCSK_SKI1_1	300	304	PF00082	0.488
CLV_PCSK_SKI1_1	96	100	PF00082	0.632
DEG_Nend_UBRbox_1	1	4	PF02207	0.636
DEG_SCF_FBW7_1	111	116	PF00400	0.711
DOC_CKS1_1	281	286	PF01111	0.754
DOC_MAPK_DCC_7	196	204	PF00069	0.633
DOC_MAPK_MEF2A_6	196	204	PF00069	0.633
DOC_MAPK_MEF2A_6	244	253	PF00069	0.647
DOC_USP7_MATH_1	113	117	PF00917	0.647
DOC_USP7_MATH_1	132	136	PF00917	0.487
DOC_USP7_MATH_1	15	19	PF00917	0.566
DOC_USP7_MATH_1	30	34	PF00917	0.703
DOC_USP7_UBL2_3	192	196	PF12436	0.629
DOC_USP7_UBL2_3	205	209	PF12436	0.470
DOC_WW_Pin1_4	109	114	PF00397	0.673
DOC_WW_Pin1_4	255	260	PF00397	0.645
DOC_WW_Pin1_4	280	285	PF00397	0.715
DOC_WW_Pin1_4	294	299	PF00397	0.592
DOC_WW_Pin1_4	62	67	PF00397	0.686
DOC_WW_Pin1_4	96	101	PF00397	0.652
LIG_14-3-3_CanoR_1	114	122	PF00244	0.676
LIG_14-3-3_CanoR_1	133	142	PF00244	0.670
LIG_14-3-3_CanoR_1	162	167	PF00244	0.645
LIG_14-3-3_CanoR_1	173	183	PF00244	0.534
LIG_14-3-3_CanoR_1	218	225	PF00244	0.518
LIG_APCC_ABBA_1	211	216	PF00400	0.494
LIG_deltaCOP1_diTrp_1	243	248	PF00928	0.630
LIG_FHA_2	2	8	PF00498	0.665
LIG_LIR_Gen_1	18	24	PF02991	0.607
LIG_LIR_Gen_1	243	253	PF02991	0.643
LIG_LIR_Nem_3	18	23	PF02991	0.607
LIG_LIR_Nem_3	243	249	PF02991	0.633
LIG_PDZ_Class_2	308	313	PF00595	0.433
LIG_SH2_PTP2	127	130	PF00017	0.631
LIG_SH2_SRC	127	130	PF00017	0.634
LIG_SH2_STAP1	55	59	PF00017	0.626
LIG_SH2_STAT5	127	130	PF00017	0.656
LIG_SH3_1	278	284	PF00018	0.606
LIG_SH3_2	200	205	PF14604	0.651
LIG_SH3_3	116	122	PF00018	0.707
LIG_SH3_3	125	131	PF00018	0.687
LIG_SH3_3	187	193	PF00018	0.550
LIG_SH3_3	194	200	PF00018	0.535
LIG_SH3_3	268	274	PF00018	0.691
LIG_SH3_3	278	284	PF00018	0.668
LIG_SH3_4	192	199	PF00018	0.658
LIG_SH3_4	205	212	PF00018	0.680
LIG_UBA3_1	186	192	PF00899	0.414
LIG_WW_2	200	203	PF00397	0.496
MOD_CDK_SPK_2	109	114	PF00069	0.676
MOD_CDK_SPxK_1	294	300	PF00069	0.566
MOD_CDK_SPxK_1	62	68	PF00069	0.703
MOD_CDK_SPxxK_3	280	287	PF00069	0.610
MOD_CDK_SPxxK_3	294	301	PF00069	0.531
MOD_CK1_1	109	115	PF00069	0.624
MOD_CK1_1	165	171	PF00069	0.669
MOD_CK1_1	172	178	PF00069	0.599
MOD_CK1_1	221	227	PF00069	0.613
MOD_CK1_1	28	34	PF00069	0.744
MOD_CK2_1	1	7	PF00069	0.675
MOD_Cter_Amidation	253	256	PF01082	0.519
MOD_Cter_Amidation	290	293	PF01082	0.665
MOD_Cter_Amidation	68	71	PF01082	0.592
MOD_GlcNHglycan	149	152	PF01048	0.702
MOD_GlcNHglycan	158	161	PF01048	0.653
MOD_GlcNHglycan	220	223	PF01048	0.610
MOD_GlcNHglycan	239	242	PF01048	0.407
MOD_GSK3_1	109	116	PF00069	0.607
MOD_GSK3_1	156	163	PF00069	0.694
MOD_GSK3_1	165	172	PF00069	0.641
MOD_GSK3_1	43	50	PF00069	0.529
MOD_N-GLC_1	173	178	PF02516	0.620
MOD_N-GLC_1	264	269	PF02516	0.554
MOD_NEK2_1	1	6	PF00069	0.633
MOD_NEK2_2	15	20	PF00069	0.522
MOD_PIKK_1	133	139	PF00454	0.429
MOD_PIKK_1	165	171	PF00454	0.629
MOD_PK_1	162	168	PF00069	0.719
MOD_PKA_2	113	119	PF00069	0.613
MOD_PKA_2	132	138	PF00069	0.605
MOD_PKA_2	172	178	PF00069	0.626
MOD_PKA_2	25	31	PF00069	0.568
MOD_PKA_2	88	94	PF00069	0.739
MOD_Plk_1	117	123	PF00069	0.744
MOD_Plk_1	264	270	PF00069	0.615
MOD_Plk_4	15	21	PF00069	0.507
MOD_Plk_4	182	188	PF00069	0.669
MOD_ProDKin_1	109	115	PF00069	0.672
MOD_ProDKin_1	255	261	PF00069	0.646
MOD_ProDKin_1	280	286	PF00069	0.718
MOD_ProDKin_1	294	300	PF00069	0.591
MOD_ProDKin_1	62	68	PF00069	0.687
MOD_ProDKin_1	96	102	PF00069	0.653
TRG_ER_diArg_1	122	125	PF00400	0.710
TRG_ER_diArg_1	152	155	PF00400	0.651
TRG_ER_diArg_1	206	208	PF00400	0.646
TRG_ER_diArg_1	225	227	PF00400	0.518
TRG_ER_diArg_1	292	294	PF00400	0.618
TRG_ER_diArg_1	299	301	PF00400	0.574
TRG_ER_diArg_1	67	70	PF00400	0.672
TRG_ER_diArg_1	94	96	PF00400	0.659
TRG_Pf-PMV_PEXEL_1	6	10	PF00026	0.628

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P913	Leptomonas seymouri	64%	100%
A0A1X0P1U3	Trypanosomatidae	31%	100%
A0A3Q8IFW1	Leishmania donovani	89%	100%
A0A422P3E4	Trypanosoma rangeli	34%	100%
A4HID8	Leishmania braziliensis	75%	100%
A4I5N5	Leishmania infantum	89%	100%
C9ZR04	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
Q4Q787	Leishmania major	88%	100%
V5BYT6	Trypanosoma cruzi	32%	99%