Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B0V7_LEIMU

TriTrypDb:

LmxM.29.1860

Length:

555

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0V7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0V7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	212	216	PF00656	0.501
CLV_C14_Caspase3-7	271	275	PF00656	0.634
CLV_C14_Caspase3-7	364	368	PF00656	0.662
CLV_NRD_NRD_1	333	335	PF00675	0.630
CLV_NRD_NRD_1	73	75	PF00675	0.608
CLV_PCSK_KEX2_1	162	164	PF00082	0.558
CLV_PCSK_KEX2_1	333	335	PF00082	0.632
CLV_PCSK_KEX2_1	429	431	PF00082	0.728
CLV_PCSK_KEX2_1	73	75	PF00082	0.607
CLV_PCSK_PC1ET2_1	162	164	PF00082	0.558
CLV_PCSK_PC1ET2_1	429	431	PF00082	0.684
CLV_PCSK_SKI1_1	228	232	PF00082	0.490
CLV_PCSK_SKI1_1	67	71	PF00082	0.500
CLV_PCSK_SKI1_1	74	78	PF00082	0.481
DEG_COP1_1	351	362	PF00400	0.655
DEG_COP1_1	7	15	PF00400	0.487
DEG_SCF_TRCP1_1	367	372	PF00400	0.541
DEG_SPOP_SBC_1	105	109	PF00917	0.562
DEG_SPOP_SBC_1	273	277	PF00917	0.569
DEG_SPOP_SBC_1	434	438	PF00917	0.535
DOC_CYCLIN_RxL_1	515	524	PF00134	0.634
DOC_CYCLIN_yCln2_LP_2	47	53	PF00134	0.492
DOC_MAPK_DCC_7	333	341	PF00069	0.640
DOC_MAPK_gen_1	333	341	PF00069	0.640
DOC_MAPK_gen_1	43	51	PF00069	0.517
DOC_MAPK_MEF2A_6	120	128	PF00069	0.503
DOC_MAPK_MEF2A_6	333	341	PF00069	0.640
DOC_MAPK_MEF2A_6	43	51	PF00069	0.517
DOC_PP1_RVXF_1	300	306	PF00149	0.547
DOC_PP1_RVXF_1	516	523	PF00149	0.635
DOC_PP2B_LxvP_1	47	50	PF13499	0.502
DOC_PP2B_PxIxI_1	23	29	PF00149	0.554
DOC_USP7_MATH_1	104	108	PF00917	0.645
DOC_USP7_MATH_1	164	168	PF00917	0.507
DOC_USP7_MATH_1	209	213	PF00917	0.598
DOC_USP7_MATH_1	222	226	PF00917	0.550
DOC_USP7_MATH_1	233	237	PF00917	0.606
DOC_USP7_MATH_1	247	251	PF00917	0.782
DOC_USP7_MATH_1	273	277	PF00917	0.623
DOC_USP7_MATH_1	362	366	PF00917	0.780
DOC_USP7_MATH_1	440	444	PF00917	0.768
DOC_USP7_MATH_1	450	454	PF00917	0.632
DOC_USP7_MATH_1	502	506	PF00917	0.633
DOC_WW_Pin1_4	18	23	PF00397	0.657
DOC_WW_Pin1_4	250	255	PF00397	0.642
DOC_WW_Pin1_4	317	322	PF00397	0.597
DOC_WW_Pin1_4	34	39	PF00397	0.501
DOC_WW_Pin1_4	358	363	PF00397	0.608
DOC_WW_Pin1_4	402	407	PF00397	0.711
DOC_WW_Pin1_4	472	477	PF00397	0.698
DOC_WW_Pin1_4	487	492	PF00397	0.702
DOC_WW_Pin1_4	498	503	PF00397	0.531
DOC_WW_Pin1_4	530	535	PF00397	0.641
DOC_WW_Pin1_4	540	545	PF00397	0.632
LIG_14-3-3_CanoR_1	106	111	PF00244	0.649
LIG_14-3-3_CanoR_1	163	169	PF00244	0.480
LIG_14-3-3_CanoR_1	29	38	PF00244	0.588
LIG_14-3-3_CanoR_1	290	296	PF00244	0.502
LIG_14-3-3_CanoR_1	43	48	PF00244	0.615
LIG_14-3-3_CanoR_1	518	523	PF00244	0.684
LIG_14-3-3_CanoR_1	67	73	PF00244	0.507
LIG_FHA_1	15	21	PF00498	0.549
LIG_FHA_1	429	435	PF00498	0.572
LIG_FHA_1	44	50	PF00498	0.518
LIG_FHA_1	5	11	PF00498	0.522
LIG_FHA_1	541	547	PF00498	0.521
LIG_FHA_1	77	83	PF00498	0.394
LIG_FHA_2	106	112	PF00498	0.649
LIG_FHA_2	269	275	PF00498	0.675
LIG_FHA_2	282	288	PF00498	0.402
LIG_FHA_2	292	298	PF00498	0.541
LIG_FHA_2	465	471	PF00498	0.718
LIG_FHA_2	488	494	PF00498	0.619
LIG_FHA_2	54	60	PF00498	0.439
LIG_FHA_2	73	79	PF00498	0.460
LIG_LIR_Apic_2	416	421	PF02991	0.548
LIG_LIR_Gen_1	14	23	PF02991	0.545
LIG_LIR_Gen_1	146	155	PF02991	0.380
LIG_LIR_Gen_1	283	293	PF02991	0.496
LIG_LIR_Gen_1	94	105	PF02991	0.594
LIG_LIR_Nem_3	14	18	PF02991	0.569
LIG_LIR_Nem_3	146	152	PF02991	0.363
LIG_LIR_Nem_3	283	288	PF02991	0.525
LIG_LIR_Nem_3	94	100	PF02991	0.580
LIG_SH2_CRK	418	422	PF00017	0.549
LIG_SH2_NCK_1	539	543	PF00017	0.596
LIG_SH2_STAT5	317	320	PF00017	0.598
LIG_SH2_STAT5	418	421	PF00017	0.484
LIG_SH2_STAT5	68	71	PF00017	0.543
LIG_SH2_STAT5	97	100	PF00017	0.578
LIG_SH3_1	403	409	PF00018	0.692
LIG_SH3_2	221	226	PF14604	0.540
LIG_SH3_2	406	411	PF14604	0.678
LIG_SH3_2	473	478	PF14604	0.531
LIG_SH3_3	218	224	PF00018	0.615
LIG_SH3_3	315	321	PF00018	0.593
LIG_SH3_3	32	38	PF00018	0.550
LIG_SH3_3	329	335	PF00018	0.501
LIG_SH3_3	356	362	PF00018	0.651
LIG_SH3_3	377	383	PF00018	0.646
LIG_SH3_3	403	409	PF00018	0.692
LIG_SH3_3	470	476	PF00018	0.568
LIG_SH3_3	7	13	PF00018	0.578
LIG_SUMO_SIM_par_1	127	135	PF11976	0.595
LIG_SUMO_SIM_par_1	16	21	PF11976	0.532
LIG_SUMO_SIM_par_1	209	215	PF11976	0.520
LIG_SUMO_SIM_par_1	6	11	PF11976	0.495
LIG_SxIP_EBH_1	29	40	PF03271	0.495
LIG_TRAF2_1	109	112	PF00917	0.496
LIG_TRAF2_1	276	279	PF00917	0.631
LIG_TRAF2_1	390	393	PF00917	0.524
LIG_TRAF2_1	456	459	PF00917	0.646
LIG_UBA3_1	69	77	PF00899	0.517
LIG_WRC_WIRS_1	12	17	PF05994	0.501
LIG_WW_3	379	383	PF00397	0.639
MOD_CDC14_SPxK_1	320	323	PF00782	0.596
MOD_CDC14_SPxK_1	475	478	PF00782	0.528
MOD_CDK_SPK_2	358	363	PF00069	0.696
MOD_CDK_SPxK_1	317	323	PF00069	0.597
MOD_CDK_SPxK_1	472	478	PF00069	0.533
MOD_CDK_SPxxK_3	540	547	PF00069	0.558
MOD_CK1_1	14	20	PF00069	0.566
MOD_CK1_1	250	256	PF00069	0.729
MOD_CK1_1	291	297	PF00069	0.549
MOD_CK1_1	348	354	PF00069	0.838
MOD_CK1_1	361	367	PF00069	0.732
MOD_CK1_1	368	374	PF00069	0.673
MOD_CK1_1	422	428	PF00069	0.615
MOD_CK1_1	438	444	PF00069	0.583
MOD_CK1_1	487	493	PF00069	0.743
MOD_CK1_1	540	546	PF00069	0.756
MOD_CK2_1	105	111	PF00069	0.579
MOD_CK2_1	272	278	PF00069	0.652
MOD_CK2_1	291	297	PF00069	0.620
MOD_CK2_1	316	322	PF00069	0.538
MOD_CK2_1	352	358	PF00069	0.662
MOD_CK2_1	387	393	PF00069	0.756
MOD_CK2_1	464	470	PF00069	0.720
MOD_CK2_1	518	524	PF00069	0.617
MOD_CK2_1	53	59	PF00069	0.456
MOD_CK2_1	72	78	PF00069	0.535
MOD_GlcNHglycan	235	238	PF01048	0.639
MOD_GlcNHglycan	348	351	PF01048	0.593
MOD_GlcNHglycan	364	367	PF01048	0.693
MOD_GlcNHglycan	38	41	PF01048	0.517
MOD_GlcNHglycan	437	440	PF01048	0.655
MOD_GlcNHglycan	452	455	PF01048	0.565
MOD_GlcNHglycan	486	489	PF01048	0.651
MOD_GlcNHglycan	538	542	PF01048	0.783
MOD_GSK3_1	14	21	PF00069	0.544
MOD_GSK3_1	196	203	PF00069	0.604
MOD_GSK3_1	222	229	PF00069	0.570
MOD_GSK3_1	233	240	PF00069	0.634
MOD_GSK3_1	243	250	PF00069	0.610
MOD_GSK3_1	268	275	PF00069	0.671
MOD_GSK3_1	30	37	PF00069	0.545
MOD_GSK3_1	341	348	PF00069	0.807
MOD_GSK3_1	354	361	PF00069	0.618
MOD_GSK3_1	365	372	PF00069	0.734
MOD_GSK3_1	4	11	PF00069	0.609
MOD_GSK3_1	419	426	PF00069	0.621
MOD_GSK3_1	434	441	PF00069	0.550
MOD_GSK3_1	446	453	PF00069	0.639
MOD_GSK3_1	461	468	PF00069	0.555
MOD_GSK3_1	480	487	PF00069	0.567
MOD_GSK3_1	49	56	PF00069	0.417
MOD_GSK3_1	498	505	PF00069	0.517
MOD_GSK3_1	68	75	PF00069	0.515
MOD_N-GLC_1	345	350	PF02516	0.571
MOD_NEK2_1	144	149	PF00069	0.592
MOD_NEK2_1	4	9	PF00069	0.549
MOD_NEK2_1	435	440	PF00069	0.674
MOD_NEK2_1	446	451	PF00069	0.649
MOD_NEK2_1	484	489	PF00069	0.620
MOD_NEK2_1	72	77	PF00069	0.526
MOD_NEK2_1	86	91	PF00069	0.396
MOD_NEK2_2	164	169	PF00069	0.420
MOD_NEK2_2	53	58	PF00069	0.459
MOD_NEK2_2	68	73	PF00069	0.501
MOD_PIKK_1	341	347	PF00454	0.668
MOD_PIKK_1	440	446	PF00454	0.620
MOD_PKA_1	162	168	PF00069	0.587
MOD_PKA_2	105	111	PF00069	0.579
MOD_PKA_2	144	150	PF00069	0.388
MOD_PKA_2	162	168	PF00069	0.645
MOD_PKA_2	362	368	PF00069	0.770
MOD_PKA_2	72	78	PF00069	0.556
MOD_PKB_1	478	486	PF00069	0.527
MOD_Plk_2-3	130	136	PF00069	0.519
MOD_Plk_2-3	274	280	PF00069	0.552
MOD_Plk_2-3	281	287	PF00069	0.421
MOD_Plk_4	11	17	PF00069	0.546
MOD_Plk_4	144	150	PF00069	0.388
MOD_Plk_4	480	486	PF00069	0.596
MOD_ProDKin_1	18	24	PF00069	0.658
MOD_ProDKin_1	250	256	PF00069	0.643
MOD_ProDKin_1	317	323	PF00069	0.597
MOD_ProDKin_1	34	40	PF00069	0.500
MOD_ProDKin_1	358	364	PF00069	0.608
MOD_ProDKin_1	402	408	PF00069	0.711
MOD_ProDKin_1	472	478	PF00069	0.700
MOD_ProDKin_1	487	493	PF00069	0.702
MOD_ProDKin_1	498	504	PF00069	0.530
MOD_ProDKin_1	530	536	PF00069	0.643
MOD_ProDKin_1	540	546	PF00069	0.634
MOD_SUMO_for_1	193	196	PF00179	0.451
MOD_SUMO_rev_2	274	284	PF00179	0.522
TRG_ENDOCYTIC_2	149	152	PF00928	0.386
TRG_ENDOCYTIC_2	97	100	PF00928	0.567
TRG_ER_diArg_1	302	305	PF00400	0.559
TRG_ER_diArg_1	332	334	PF00400	0.631
TRG_ER_diArg_1	72	74	PF00400	0.531
TRG_Pf-PMV_PEXEL_1	518	523	PF00026	0.684

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X3E1	Leishmania donovani	78%	100%
A4H927	Leishmania braziliensis	62%	100%
A4I5L2	Leishmania infantum	78%	100%
Q4Q7A9	Leishmania major	76%	97%