LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

RING-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
RING-type domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B0V5_LEIMU
TriTrypDb:
LmxM.29.1840
Length:
821

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0V5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0V5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 55 59 PF00656 0.820
CLV_C14_Caspase3-7 666 670 PF00656 0.767
CLV_C14_Caspase3-7 768 772 PF00656 0.703
CLV_NRD_NRD_1 301 303 PF00675 0.588
CLV_NRD_NRD_1 444 446 PF00675 0.855
CLV_NRD_NRD_1 448 450 PF00675 0.797
CLV_NRD_NRD_1 575 577 PF00675 0.813
CLV_NRD_NRD_1 666 668 PF00675 0.849
CLV_NRD_NRD_1 717 719 PF00675 0.788
CLV_NRD_NRD_1 720 722 PF00675 0.715
CLV_NRD_NRD_1 724 726 PF00675 0.650
CLV_PCSK_FUR_1 445 449 PF00082 0.860
CLV_PCSK_FUR_1 718 722 PF00082 0.777
CLV_PCSK_KEX2_1 301 303 PF00082 0.557
CLV_PCSK_KEX2_1 446 448 PF00082 0.858
CLV_PCSK_KEX2_1 532 534 PF00082 0.730
CLV_PCSK_KEX2_1 575 577 PF00082 0.776
CLV_PCSK_KEX2_1 653 655 PF00082 0.855
CLV_PCSK_KEX2_1 717 719 PF00082 0.788
CLV_PCSK_KEX2_1 720 722 PF00082 0.715
CLV_PCSK_KEX2_1 723 725 PF00082 0.667
CLV_PCSK_PC1ET2_1 446 448 PF00082 0.858
CLV_PCSK_PC1ET2_1 532 534 PF00082 0.730
CLV_PCSK_PC1ET2_1 653 655 PF00082 0.855
CLV_PCSK_PC7_1 720 726 PF00082 0.671
CLV_PCSK_SKI1_1 101 105 PF00082 0.548
CLV_PCSK_SKI1_1 301 305 PF00082 0.558
CLV_PCSK_SKI1_1 344 348 PF00082 0.766
CLV_PCSK_SKI1_1 449 453 PF00082 0.783
CLV_PCSK_SKI1_1 468 472 PF00082 0.552
CLV_PCSK_SKI1_1 532 536 PF00082 0.541
CLV_PCSK_SKI1_1 691 695 PF00082 0.707
DEG_APCC_DBOX_1 100 108 PF00400 0.548
DEG_APCC_DBOX_1 300 308 PF00400 0.562
DEG_ODPH_VHL_1 16 28 PF01847 0.529
DEG_SPOP_SBC_1 17 21 PF00917 0.652
DEG_SPOP_SBC_1 170 174 PF00917 0.717
DEG_SPOP_SBC_1 226 230 PF00917 0.756
DEG_SPOP_SBC_1 29 33 PF00917 0.624
DOC_CKS1_1 389 394 PF01111 0.566
DOC_CYCLIN_yCln2_LP_2 141 147 PF00134 0.565
DOC_CYCLIN_yCln2_LP_2 480 486 PF00134 0.547
DOC_MAPK_gen_1 260 268 PF00069 0.768
DOC_MAPK_HePTP_8 780 792 PF00069 0.650
DOC_MAPK_MEF2A_6 352 359 PF00069 0.612
DOC_MAPK_MEF2A_6 783 792 PF00069 0.656
DOC_PP1_RVXF_1 777 783 PF00149 0.355
DOC_PP2B_LxvP_1 141 144 PF13499 0.613
DOC_PP2B_LxvP_1 156 159 PF13499 0.759
DOC_PP2B_LxvP_1 400 403 PF13499 0.801
DOC_PP2B_LxvP_1 480 483 PF13499 0.631
DOC_PP2B_LxvP_1 537 540 PF13499 0.764
DOC_PP4_FxxP_1 380 383 PF00568 0.786
DOC_USP7_MATH_1 129 133 PF00917 0.547
DOC_USP7_MATH_1 170 174 PF00917 0.809
DOC_USP7_MATH_1 179 183 PF00917 0.650
DOC_USP7_MATH_1 220 224 PF00917 0.694
DOC_USP7_MATH_1 225 229 PF00917 0.678
DOC_USP7_MATH_1 284 288 PF00917 0.716
DOC_USP7_MATH_1 29 33 PF00917 0.711
DOC_USP7_MATH_1 293 297 PF00917 0.816
DOC_USP7_MATH_1 394 398 PF00917 0.735
DOC_USP7_MATH_1 403 407 PF00917 0.823
DOC_USP7_MATH_1 453 457 PF00917 0.559
DOC_USP7_MATH_1 47 51 PF00917 0.542
DOC_USP7_MATH_1 514 518 PF00917 0.818
DOC_USP7_MATH_1 61 65 PF00917 0.542
DOC_USP7_MATH_1 632 636 PF00917 0.571
DOC_USP7_MATH_1 663 667 PF00917 0.779
DOC_USP7_MATH_1 682 686 PF00917 0.586
DOC_USP7_MATH_1 687 691 PF00917 0.778
DOC_USP7_MATH_1 755 759 PF00917 0.724
DOC_USP7_UBL2_3 804 808 PF12436 0.820
DOC_WW_Pin1_4 143 148 PF00397 0.778
DOC_WW_Pin1_4 159 164 PF00397 0.627
DOC_WW_Pin1_4 198 203 PF00397 0.718
DOC_WW_Pin1_4 232 237 PF00397 0.675
DOC_WW_Pin1_4 266 271 PF00397 0.826
DOC_WW_Pin1_4 274 279 PF00397 0.740
DOC_WW_Pin1_4 308 313 PF00397 0.686
DOC_WW_Pin1_4 384 389 PF00397 0.806
DOC_WW_Pin1_4 558 563 PF00397 0.620
DOC_WW_Pin1_4 593 598 PF00397 0.551
DOC_WW_Pin1_4 607 612 PF00397 0.829
DOC_WW_Pin1_4 626 631 PF00397 0.504
DOC_WW_Pin1_4 63 68 PF00397 0.539
DOC_WW_Pin1_4 769 774 PF00397 0.687
DOC_WW_Pin1_4 797 802 PF00397 0.681
LIG_14-3-3_CanoR_1 165 175 PF00244 0.780
LIG_14-3-3_CanoR_1 241 249 PF00244 0.822
LIG_14-3-3_CanoR_1 263 269 PF00244 0.568
LIG_14-3-3_CanoR_1 425 433 PF00244 0.557
LIG_14-3-3_CanoR_1 533 537 PF00244 0.549
LIG_14-3-3_CanoR_1 723 729 PF00244 0.681
LIG_BIR_II_1 1 5 PF00653 0.764
LIG_BIR_III_2 798 802 PF00653 0.611
LIG_EVH1_1 389 393 PF00568 0.563
LIG_FHA_1 113 119 PF00498 0.678
LIG_FHA_1 190 196 PF00498 0.835
LIG_FHA_1 245 251 PF00498 0.822
LIG_FHA_1 292 298 PF00498 0.757
LIG_FHA_1 384 390 PF00498 0.860
LIG_FHA_1 594 600 PF00498 0.604
LIG_FHA_1 642 648 PF00498 0.845
LIG_FHA_1 85 91 PF00498 0.760
LIG_FHA_1 98 104 PF00498 0.646
LIG_FHA_2 256 262 PF00498 0.708
LIG_FHA_2 309 315 PF00498 0.771
LIG_FHA_2 34 40 PF00498 0.823
LIG_FHA_2 725 731 PF00498 0.575
LIG_FHA_2 8 14 PF00498 0.619
LIG_LIR_Apic_2 379 383 PF02991 0.785
LIG_LIR_Gen_1 775 785 PF02991 0.354
LIG_LIR_Nem_3 421 427 PF02991 0.778
LIG_LIR_Nem_3 775 780 PF02991 0.351
LIG_LIR_Nem_3 800 805 PF02991 0.805
LIG_MYND_1 105 109 PF01753 0.834
LIG_SH2_CRK 777 781 PF00017 0.537
LIG_SH2_NCK_1 254 258 PF00017 0.720
LIG_SH2_SRC 254 257 PF00017 0.640
LIG_SH2_SRC 784 787 PF00017 0.657
LIG_SH2_STAP1 777 781 PF00017 0.635
LIG_SH2_STAT3 581 584 PF00017 0.856
LIG_SH2_STAT5 715 718 PF00017 0.762
LIG_SH3_1 749 755 PF00018 0.755
LIG_SH3_3 141 147 PF00018 0.565
LIG_SH3_3 161 167 PF00018 0.771
LIG_SH3_3 185 191 PF00018 0.603
LIG_SH3_3 201 207 PF00018 0.714
LIG_SH3_3 273 279 PF00018 0.845
LIG_SH3_3 316 322 PF00018 0.837
LIG_SH3_3 387 393 PF00018 0.599
LIG_SH3_3 475 481 PF00018 0.544
LIG_SH3_3 533 539 PF00018 0.662
LIG_SH3_3 605 611 PF00018 0.753
LIG_SH3_3 676 682 PF00018 0.579
LIG_SH3_3 749 755 PF00018 0.755
LIG_SUMO_SIM_par_1 594 602 PF11976 0.551
LIG_TRAF2_1 197 200 PF00917 0.567
LIG_TRAF2_1 211 214 PF00917 0.624
LIG_TRAF2_1 259 262 PF00917 0.736
LIG_TRAF2_1 311 314 PF00917 0.770
LIG_TRAF2_1 497 500 PF00917 0.522
LIG_WW_1 712 715 PF00397 0.789
LIG_WW_3 162 166 PF00397 0.673
MOD_CDC14_SPxK_1 162 165 PF00782 0.772
MOD_CDK_SPxK_1 159 165 PF00069 0.781
MOD_CDK_SPxxK_3 63 70 PF00069 0.541
MOD_CDK_SPxxK_3 797 804 PF00069 0.691
MOD_CK1_1 123 129 PF00069 0.575
MOD_CK1_1 169 175 PF00069 0.828
MOD_CK1_1 189 195 PF00069 0.536
MOD_CK1_1 198 204 PF00069 0.671
MOD_CK1_1 2 8 PF00069 0.772
MOD_CK1_1 229 235 PF00069 0.851
MOD_CK1_1 269 275 PF00069 0.611
MOD_CK1_1 31 37 PF00069 0.610
MOD_CK1_1 358 364 PF00069 0.769
MOD_CK1_1 406 412 PF00069 0.791
MOD_CK1_1 52 58 PF00069 0.607
MOD_CK1_1 591 597 PF00069 0.767
MOD_CK1_1 601 607 PF00069 0.661
MOD_CK1_1 610 616 PF00069 0.763
MOD_CK1_1 634 640 PF00069 0.642
MOD_CK1_1 772 778 PF00069 0.359
MOD_CK1_1 797 803 PF00069 0.704
MOD_CK1_1 81 87 PF00069 0.795
MOD_CK1_1 9 15 PF00069 0.737
MOD_CK2_1 255 261 PF00069 0.803
MOD_CK2_1 307 313 PF00069 0.775
MOD_CK2_1 31 37 PF00069 0.792
MOD_CK2_1 520 526 PF00069 0.778
MOD_CK2_1 7 13 PF00069 0.615
MOD_CK2_1 724 730 PF00069 0.639
MOD_CK2_1 762 768 PF00069 0.656
MOD_CK2_1 804 810 PF00069 0.526
MOD_GlcNHglycan 168 171 PF01048 0.744
MOD_GlcNHglycan 223 226 PF01048 0.688
MOD_GlcNHglycan 231 234 PF01048 0.762
MOD_GlcNHglycan 291 294 PF01048 0.833
MOD_GlcNHglycan 297 300 PF01048 0.736
MOD_GlcNHglycan 322 325 PF01048 0.614
MOD_GlcNHglycan 33 36 PF01048 0.598
MOD_GlcNHglycan 331 334 PF01048 0.704
MOD_GlcNHglycan 427 430 PF01048 0.571
MOD_GlcNHglycan 49 52 PF01048 0.552
MOD_GlcNHglycan 516 519 PF01048 0.804
MOD_GlcNHglycan 522 525 PF01048 0.766
MOD_GlcNHglycan 601 604 PF01048 0.767
MOD_GlcNHglycan 62 66 PF01048 0.562
MOD_GlcNHglycan 669 672 PF01048 0.743
MOD_GSK3_1 1 8 PF00069 0.778
MOD_GSK3_1 123 130 PF00069 0.737
MOD_GSK3_1 165 172 PF00069 0.825
MOD_GSK3_1 221 228 PF00069 0.793
MOD_GSK3_1 231 238 PF00069 0.730
MOD_GSK3_1 240 247 PF00069 0.559
MOD_GSK3_1 264 271 PF00069 0.636
MOD_GSK3_1 289 296 PF00069 0.803
MOD_GSK3_1 29 36 PF00069 0.530
MOD_GSK3_1 38 45 PF00069 0.756
MOD_GSK3_1 384 391 PF00069 0.732
MOD_GSK3_1 394 401 PF00069 0.625
MOD_GSK3_1 554 561 PF00069 0.745
MOD_GSK3_1 606 613 PF00069 0.769
MOD_GSK3_1 614 621 PF00069 0.713
MOD_GSK3_1 631 638 PF00069 0.733
MOD_GSK3_1 659 666 PF00069 0.693
MOD_GSK3_1 682 689 PF00069 0.556
MOD_GSK3_1 719 726 PF00069 0.728
MOD_GSK3_1 78 85 PF00069 0.806
MOD_GSK3_1 804 811 PF00069 0.523
MOD_LATS_1 423 429 PF00433 0.569
MOD_N-GLC_1 123 128 PF02516 0.637
MOD_N-GLC_1 639 644 PF02516 0.692
MOD_NEK2_1 1 6 PF00069 0.782
MOD_NEK2_1 231 236 PF00069 0.657
MOD_NEK2_1 264 269 PF00069 0.642
MOD_NEK2_1 297 302 PF00069 0.673
MOD_NEK2_1 307 312 PF00069 0.712
MOD_NEK2_1 357 362 PF00069 0.741
MOD_NEK2_1 38 43 PF00069 0.689
MOD_NEK2_1 452 457 PF00069 0.562
MOD_NEK2_1 46 51 PF00069 0.587
MOD_NEK2_1 556 561 PF00069 0.745
MOD_PIKK_1 179 185 PF00454 0.754
MOD_PIKK_1 195 201 PF00454 0.551
MOD_PIKK_1 235 241 PF00454 0.843
MOD_PIKK_1 431 437 PF00454 0.550
MOD_PKA_1 532 538 PF00069 0.549
MOD_PKA_1 667 673 PF00069 0.841
MOD_PKA_1 723 729 PF00069 0.661
MOD_PKA_2 240 246 PF00069 0.750
MOD_PKA_2 264 270 PF00069 0.570
MOD_PKA_2 520 526 PF00069 0.727
MOD_PKA_2 532 538 PF00069 0.596
MOD_PKA_2 719 725 PF00069 0.768
MOD_PKB_1 721 729 PF00069 0.759
MOD_Plk_1 244 250 PF00069 0.779
MOD_Plk_1 272 278 PF00069 0.551
MOD_Plk_1 70 76 PF00069 0.583
MOD_Plk_4 503 509 PF00069 0.730
MOD_Plk_4 532 538 PF00069 0.549
MOD_Plk_4 772 778 PF00069 0.359
MOD_ProDKin_1 143 149 PF00069 0.779
MOD_ProDKin_1 159 165 PF00069 0.629
MOD_ProDKin_1 198 204 PF00069 0.716
MOD_ProDKin_1 232 238 PF00069 0.674
MOD_ProDKin_1 266 272 PF00069 0.821
MOD_ProDKin_1 274 280 PF00069 0.739
MOD_ProDKin_1 308 314 PF00069 0.688
MOD_ProDKin_1 384 390 PF00069 0.801
MOD_ProDKin_1 558 564 PF00069 0.622
MOD_ProDKin_1 593 599 PF00069 0.553
MOD_ProDKin_1 607 613 PF00069 0.833
MOD_ProDKin_1 626 632 PF00069 0.503
MOD_ProDKin_1 63 69 PF00069 0.539
MOD_ProDKin_1 769 775 PF00069 0.685
MOD_ProDKin_1 797 803 PF00069 0.685
MOD_SUMO_for_1 815 818 PF00179 0.637
MOD_SUMO_rev_2 526 534 PF00179 0.656
TRG_DiLeu_BaEn_4 261 267 PF01217 0.767
TRG_DiLeu_BaLyEn_6 776 781 PF01217 0.339
TRG_ENDOCYTIC_2 777 780 PF00928 0.558
TRG_ER_diArg_1 445 448 PF00400 0.859
TRG_ER_diArg_1 574 576 PF00400 0.831
TRG_ER_diArg_1 717 720 PF00400 0.784
TRG_ER_diArg_1 721 724 PF00400 0.695
TRG_NLS_MonoCore_2 444 449 PF00514 0.858
TRG_NLS_MonoExtC_3 444 449 PF00514 0.858
TRG_NLS_MonoExtN_4 442 449 PF00514 0.854
TRG_Pf-PMV_PEXEL_1 739 743 PF00026 0.593

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7X3D6 Leishmania donovani 79% 100%
A4H929 Leishmania braziliensis 51% 100%
A4I5L0 Leishmania infantum 79% 100%
Q4Q7B1 Leishmania major 77% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS