Putative DNAJ domain protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNAJ domain protein, putative

Species:

Leishmania mexicana

UniProt:

E9B0V1_LEIMU

TriTrypDb:

LmxM.29.1790

Length:

740

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0V1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0V1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	344	348	PF00656	0.511
CLV_C14_Caspase3-7	77	81	PF00656	0.415
CLV_NRD_NRD_1	209	211	PF00675	0.536
CLV_NRD_NRD_1	266	268	PF00675	0.634
CLV_NRD_NRD_1	47	49	PF00675	0.518
CLV_NRD_NRD_1	624	626	PF00675	0.648
CLV_NRD_NRD_1	687	689	PF00675	0.671
CLV_PCSK_FUR_1	250	254	PF00082	0.395
CLV_PCSK_KEX2_1	199	201	PF00082	0.780
CLV_PCSK_KEX2_1	209	211	PF00082	0.574
CLV_PCSK_KEX2_1	218	220	PF00082	0.627
CLV_PCSK_KEX2_1	252	254	PF00082	0.559
CLV_PCSK_KEX2_1	266	268	PF00082	0.524
CLV_PCSK_KEX2_1	624	626	PF00082	0.721
CLV_PCSK_KEX2_1	650	652	PF00082	0.564
CLV_PCSK_KEX2_1	687	689	PF00082	0.671
CLV_PCSK_KEX2_1	737	739	PF00082	0.671
CLV_PCSK_KEX2_1	99	101	PF00082	0.728
CLV_PCSK_PC1ET2_1	199	201	PF00082	0.672
CLV_PCSK_PC1ET2_1	218	220	PF00082	0.662
CLV_PCSK_PC1ET2_1	252	254	PF00082	0.559
CLV_PCSK_PC1ET2_1	650	652	PF00082	0.564
CLV_PCSK_PC1ET2_1	737	739	PF00082	0.671
CLV_PCSK_PC1ET2_1	99	101	PF00082	0.728
CLV_PCSK_PC7_1	262	268	PF00082	0.687
CLV_PCSK_SKI1_1	219	223	PF00082	0.551
CLV_PCSK_SKI1_1	252	256	PF00082	0.571
CLV_PCSK_SKI1_1	36	40	PF00082	0.287
CLV_PCSK_SKI1_1	454	458	PF00082	0.584
CLV_PCSK_SKI1_1	466	470	PF00082	0.546
CLV_PCSK_SKI1_1	49	53	PF00082	0.358
CLV_PCSK_SKI1_1	589	593	PF00082	0.722
CLV_PCSK_SKI1_1	650	654	PF00082	0.717
CLV_PCSK_SKI1_1	715	719	PF00082	0.475
CLV_Separin_Metazoa	363	367	PF03568	0.779
DEG_APCC_DBOX_1	301	309	PF00400	0.441
DEG_Kelch_Keap1_1	530	535	PF01344	0.734
DEG_SCF_FBW7_2	604	611	PF00400	0.730
DOC_CYCLIN_RxL_1	250	259	PF00134	0.561
DOC_MAPK_gen_1	687	693	PF00069	0.682
DOC_MAPK_gen_1	79	89	PF00069	0.415
DOC_PP2B_LxvP_1	194	197	PF13499	0.658
DOC_PP4_FxxP_1	457	460	PF00568	0.575
DOC_PP4_FxxP_1	98	101	PF00568	0.755
DOC_USP7_MATH_1	103	107	PF00917	0.644
DOC_USP7_MATH_1	125	129	PF00917	0.742
DOC_USP7_MATH_1	16	20	PF00917	0.655
DOC_USP7_MATH_1	174	178	PF00917	0.708
DOC_USP7_MATH_1	179	183	PF00917	0.702
DOC_USP7_MATH_1	211	215	PF00917	0.776
DOC_USP7_MATH_1	228	232	PF00917	0.785
DOC_USP7_MATH_1	243	247	PF00917	0.428
DOC_USP7_MATH_1	353	357	PF00917	0.687
DOC_USP7_MATH_1	458	462	PF00917	0.645
DOC_USP7_MATH_1	470	474	PF00917	0.706
DOC_USP7_MATH_1	489	493	PF00917	0.516
DOC_USP7_MATH_1	522	526	PF00917	0.726
DOC_USP7_MATH_1	537	541	PF00917	0.564
DOC_USP7_MATH_1	570	574	PF00917	0.724
DOC_USP7_MATH_1	59	63	PF00917	0.288
DOC_USP7_MATH_1	713	717	PF00917	0.653
DOC_USP7_UBL2_3	195	199	PF12436	0.665
DOC_USP7_UBL2_3	218	222	PF12436	0.553
DOC_USP7_UBL2_3	504	508	PF12436	0.661
DOC_USP7_UBL2_3	650	654	PF12436	0.564
DOC_USP7_UBL2_3	664	668	PF12436	0.534
DOC_WW_Pin1_4	319	324	PF00397	0.637
DOC_WW_Pin1_4	333	338	PF00397	0.568
DOC_WW_Pin1_4	395	400	PF00397	0.706
DOC_WW_Pin1_4	426	431	PF00397	0.730
DOC_WW_Pin1_4	456	461	PF00397	0.844
DOC_WW_Pin1_4	568	573	PF00397	0.666
DOC_WW_Pin1_4	595	600	PF00397	0.737
DOC_WW_Pin1_4	6	11	PF00397	0.654
DOC_WW_Pin1_4	604	609	PF00397	0.697
LIG_14-3-3_CanoR_1	200	204	PF00244	0.773
LIG_14-3-3_CanoR_1	233	241	PF00244	0.618
LIG_14-3-3_CanoR_1	302	306	PF00244	0.637
LIG_14-3-3_CanoR_1	329	337	PF00244	0.673
LIG_14-3-3_CanoR_1	36	41	PF00244	0.325
LIG_14-3-3_CanoR_1	640	649	PF00244	0.551
LIG_14-3-3_CanoR_1	712	718	PF00244	0.653
LIG_14-3-3_CanoR_1	82	86	PF00244	0.266
LIG_BIR_III_2	409	413	PF00653	0.689
LIG_BRCT_BRCA1_1	397	401	PF00533	0.526
LIG_CtBP_PxDLS_1	311	315	PF00389	0.592
LIG_deltaCOP1_diTrp_1	285	290	PF00928	0.664
LIG_FHA_1	18	24	PF00498	0.507
LIG_FHA_1	333	339	PF00498	0.568
LIG_FHA_1	607	613	PF00498	0.557
LIG_FHA_1	734	740	PF00498	0.662
LIG_FHA_1	82	88	PF00498	0.266
LIG_FHA_2	293	299	PF00498	0.646
LIG_FHA_2	37	43	PF00498	0.458
LIG_FHA_2	421	427	PF00498	0.725
LIG_FHA_2	447	453	PF00498	0.556
LIG_FHA_2	527	533	PF00498	0.741
LIG_LIR_Apic_2	347	353	PF02991	0.770
LIG_LIR_Gen_1	201	212	PF02991	0.523
LIG_LIR_Gen_1	27	34	PF02991	0.517
LIG_LIR_Gen_1	64	73	PF02991	0.252
LIG_LIR_Gen_1	84	93	PF02991	0.413
LIG_LIR_Nem_3	117	123	PF02991	0.717
LIG_LIR_Nem_3	148	152	PF02991	0.653
LIG_LIR_Nem_3	201	207	PF02991	0.509
LIG_LIR_Nem_3	27	32	PF02991	0.517
LIG_LIR_Nem_3	285	290	PF02991	0.664
LIG_LIR_Nem_3	44	50	PF02991	0.307
LIG_LIR_Nem_3	64	69	PF02991	0.325
LIG_LIR_Nem_3	84	88	PF02991	0.285
LIG_MLH1_MIPbox_1	397	401	PF16413	0.526
LIG_Pex14_2	729	733	PF04695	0.634
LIG_SH2_CRK	112	116	PF00017	0.716
LIG_SH2_CRK	29	33	PF00017	0.523
LIG_SH2_CRK	47	51	PF00017	0.523
LIG_SH2_CRK	714	718	PF00017	0.643
LIG_SH2_CRK	85	89	PF00017	0.607
LIG_SH2_NCK_1	594	598	PF00017	0.559
LIG_SH2_STAP1	112	116	PF00017	0.716
LIG_SH2_STAP1	121	125	PF00017	0.581
LIG_SH2_STAP1	685	689	PF00017	0.672
LIG_SH2_STAP1	85	89	PF00017	0.607
LIG_SH2_STAT3	281	284	PF00017	0.677
LIG_SH2_STAT5	281	284	PF00017	0.677
LIG_SH3_1	617	623	PF00018	0.834
LIG_SH3_2	620	625	PF14604	0.719
LIG_SH3_3	104	110	PF00018	0.747
LIG_SH3_3	457	463	PF00018	0.816
LIG_SH3_3	476	482	PF00018	0.559
LIG_SH3_3	53	59	PF00018	0.482
LIG_SH3_3	617	623	PF00018	0.824
LIG_TRAF2_1	322	325	PF00917	0.621
LIG_TRAF2_1	39	42	PF00917	0.523
LIG_TRAF2_1	644	647	PF00917	0.553
LIG_WRC_WIRS_1	730	735	PF05994	0.637
LIG_WW_3	463	467	PF00397	0.567
MOD_CDC14_SPxK_1	571	574	PF00782	0.559
MOD_CDC14_SPxK_1	598	601	PF00782	0.819
MOD_CDK_SPxK_1	568	574	PF00069	0.565
MOD_CDK_SPxK_1	595	601	PF00069	0.821
MOD_CDK_SPxK_1	604	610	PF00069	0.695
MOD_CDK_SPxxK_3	459	466	PF00069	0.585
MOD_CK1_1	19	25	PF00069	0.764
MOD_CK1_1	202	208	PF00069	0.731
MOD_CK1_1	214	220	PF00069	0.553
MOD_CK1_1	292	298	PF00069	0.558
MOD_CK1_1	446	452	PF00069	0.797
MOD_CK1_1	459	465	PF00069	0.596
MOD_CK1_1	492	498	PF00069	0.827
MOD_CK1_1	530	536	PF00069	0.733
MOD_CK1_1	545	551	PF00069	0.560
MOD_CK1_1	595	601	PF00069	0.713
MOD_CK2_1	292	298	PF00069	0.644
MOD_CK2_1	319	325	PF00069	0.625
MOD_CK2_1	357	363	PF00069	0.793
MOD_CK2_1	36	42	PF00069	0.435
MOD_CK2_1	420	426	PF00069	0.729
MOD_CK2_1	446	452	PF00069	0.552
MOD_CK2_1	470	476	PF00069	0.797
MOD_CK2_1	526	532	PF00069	0.742
MOD_CK2_1	600	606	PF00069	0.574
MOD_CK2_1	640	646	PF00069	0.550
MOD_CK2_1	664	670	PF00069	0.570
MOD_Cter_Amidation	452	455	PF01082	0.578
MOD_GlcNHglycan	162	165	PF01048	0.665
MOD_GlcNHglycan	213	217	PF01048	0.786
MOD_GlcNHglycan	235	238	PF01048	0.715
MOD_GlcNHglycan	391	394	PF01048	0.753
MOD_GlcNHglycan	420	423	PF01048	0.742
MOD_GlcNHglycan	472	476	PF01048	0.746
MOD_GlcNHglycan	524	527	PF01048	0.767
MOD_GlcNHglycan	529	532	PF01048	0.684
MOD_GlcNHglycan	566	569	PF01048	0.826
MOD_GlcNHglycan	6	9	PF01048	0.665
MOD_GlcNHglycan	627	630	PF01048	0.555
MOD_GlcNHglycan	642	645	PF01048	0.605
MOD_GSK3_1	174	181	PF00069	0.660
MOD_GSK3_1	198	205	PF00069	0.781
MOD_GSK3_1	288	295	PF00069	0.553
MOD_GSK3_1	32	39	PF00069	0.523
MOD_GSK3_1	328	335	PF00069	0.730
MOD_GSK3_1	341	348	PF00069	0.569
MOD_GSK3_1	353	360	PF00069	0.583
MOD_GSK3_1	373	380	PF00069	0.505
MOD_GSK3_1	387	394	PF00069	0.675
MOD_GSK3_1	420	427	PF00069	0.729
MOD_GSK3_1	488	495	PF00069	0.788
MOD_GSK3_1	511	518	PF00069	0.722
MOD_GSK3_1	522	529	PF00069	0.615
MOD_GSK3_1	537	544	PF00069	0.563
MOD_GSK3_1	564	571	PF00069	0.668
MOD_GSK3_1	585	592	PF00069	0.727
MOD_GSK3_1	6	13	PF00069	0.572
MOD_GSK3_1	600	607	PF00069	0.633
MOD_GSK3_1	698	705	PF00069	0.666
MOD_GSK3_1	729	736	PF00069	0.636
MOD_N-GLC_1	32	37	PF02516	0.523
MOD_N-GLC_1	377	382	PF02516	0.569
MOD_N-GLC_1	446	451	PF02516	0.548
MOD_N-GLC_1	59	64	PF02516	0.253
MOD_N-GLC_1	664	669	PF02516	0.571
MOD_N-GLC_2	144	146	PF02516	0.474
MOD_NEK2_1	130	135	PF00069	0.759
MOD_NEK2_1	178	183	PF00069	0.633
MOD_NEK2_1	186	191	PF00069	0.624
MOD_NEK2_1	198	203	PF00069	0.775
MOD_NEK2_1	301	306	PF00069	0.600
MOD_NEK2_1	32	37	PF00069	0.523
MOD_NEK2_1	345	350	PF00069	0.779
MOD_NEK2_1	401	406	PF00069	0.617
MOD_NEK2_1	435	440	PF00069	0.554
MOD_NEK2_1	536	541	PF00069	0.685
MOD_NEK2_1	693	698	PF00069	0.704
MOD_NEK2_1	729	734	PF00069	0.634
MOD_NEK2_2	179	184	PF00069	0.640
MOD_NEK2_2	24	29	PF00069	0.377
MOD_NMyristoyl	1	7	PF02799	0.732
MOD_PIKK_1	489	495	PF00454	0.717
MOD_PIKK_1	517	523	PF00454	0.567
MOD_PIKK_1	59	65	PF00454	0.253
MOD_PIKK_1	698	704	PF00454	0.707
MOD_PIKK_1	74	80	PF00454	0.415
MOD_PKA_1	199	205	PF00069	0.782
MOD_PKA_1	625	631	PF00069	0.554
MOD_PKA_1	650	656	PF00069	0.563
MOD_PKA_2	199	205	PF00069	0.776
MOD_PKA_2	301	307	PF00069	0.641
MOD_PKA_2	328	334	PF00069	0.667
MOD_PKA_2	545	551	PF00069	0.560
MOD_PKA_2	650	656	PF00069	0.563
MOD_PKA_2	81	87	PF00069	0.266
MOD_Plk_1	693	699	PF00069	0.705
MOD_Plk_2-3	341	347	PF00069	0.555
MOD_Plk_2-3	357	363	PF00069	0.644
MOD_Plk_4	103	109	PF00069	0.749
MOD_Plk_4	145	151	PF00069	0.711
MOD_Plk_4	199	205	PF00069	0.512
MOD_Plk_4	24	30	PF00069	0.642
MOD_Plk_4	345	351	PF00069	0.756
MOD_ProDKin_1	319	325	PF00069	0.636
MOD_ProDKin_1	333	339	PF00069	0.568
MOD_ProDKin_1	395	401	PF00069	0.707
MOD_ProDKin_1	426	432	PF00069	0.731
MOD_ProDKin_1	456	462	PF00069	0.842
MOD_ProDKin_1	568	574	PF00069	0.667
MOD_ProDKin_1	595	601	PF00069	0.740
MOD_ProDKin_1	6	12	PF00069	0.653
MOD_ProDKin_1	604	610	PF00069	0.695
MOD_SUMO_for_1	271	274	PF00179	0.610
MOD_SUMO_rev_2	446	456	PF00179	0.561
MOD_SUMO_rev_2	643	649	PF00179	0.552
TRG_DiLeu_BaEn_3	724	730	PF01217	0.623
TRG_DiLeu_BaLyEn_6	334	339	PF01217	0.686
TRG_DiLeu_BaLyEn_6	617	622	PF01217	0.569
TRG_ENDOCYTIC_2	112	115	PF00928	0.711
TRG_ENDOCYTIC_2	159	162	PF00928	0.705
TRG_ENDOCYTIC_2	29	32	PF00928	0.523
TRG_ENDOCYTIC_2	47	50	PF00928	0.523
TRG_ENDOCYTIC_2	714	717	PF00928	0.651
TRG_ENDOCYTIC_2	73	76	PF00928	0.523
TRG_ENDOCYTIC_2	85	88	PF00928	0.420
TRG_ER_diArg_1	209	211	PF00400	0.536
TRG_ER_diArg_1	266	268	PF00400	0.634
TRG_ER_diArg_1	623	625	PF00400	0.712
TRG_ER_diArg_1	675	678	PF00400	0.688
TRG_ER_diArg_1	89	92	PF00400	0.379
TRG_ER_diLys_1	735	740	PF00400	0.666

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X3L8	Leishmania donovani	80%	100%
A4H933	Leishmania braziliensis	51%	95%
A4I5K6	Leishmania infantum	80%	100%