SNF2_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9B0U6_LEIMU

TriTrypDb:

LmxM.29.1740

Length:

312

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0U6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0U6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	216	220	PF00656	0.539
CLV_NRD_NRD_1	119	121	PF00675	0.658
CLV_PCSK_KEX2_1	119	121	PF00082	0.739
CLV_PCSK_KEX2_1	263	265	PF00082	0.531
CLV_PCSK_KEX2_1	33	35	PF00082	0.625
CLV_PCSK_PC1ET2_1	263	265	PF00082	0.500
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.625
CLV_PCSK_SKI1_1	241	245	PF00082	0.593
CLV_PCSK_SKI1_1	263	267	PF00082	0.447
CLV_PCSK_SKI1_1	5	9	PF00082	0.694
DOC_CYCLIN_RxL_1	79	91	PF00134	0.406
DOC_USP7_MATH_1	32	36	PF00917	0.539
DOC_USP7_MATH_1	9	13	PF00917	0.634
DOC_USP7_UBL2_3	29	33	PF12436	0.719
DOC_WW_Pin1_4	183	188	PF00397	0.530
DOC_WW_Pin1_4	5	10	PF00397	0.733
LIG_14-3-3_CanoR_1	264	269	PF00244	0.560
LIG_AP2alpha_2	59	61	PF02296	0.566
LIG_APCC_ABBA_1	177	182	PF00400	0.500
LIG_BIR_II_1	1	5	PF00653	0.658
LIG_BRCT_BRCA1_1	228	232	PF00533	0.577
LIG_BRCT_BRCA1_1	96	100	PF00533	0.607
LIG_FHA_1	244	250	PF00498	0.599
LIG_FHA_1	46	52	PF00498	0.646
LIG_FHA_1	82	88	PF00498	0.555
LIG_FHA_2	255	261	PF00498	0.572
LIG_FHA_2	281	287	PF00498	0.471
LIG_FHA_2	72	78	PF00498	0.616
LIG_LIR_Gen_1	167	173	PF02991	0.499
LIG_LIR_Gen_1	274	282	PF02991	0.475
LIG_LIR_Gen_1	296	305	PF02991	0.494
LIG_LIR_Nem_3	147	152	PF02991	0.524
LIG_LIR_Nem_3	167	171	PF02991	0.275
LIG_LIR_Nem_3	219	224	PF02991	0.483
LIG_LIR_Nem_3	274	280	PF02991	0.490
LIG_LIR_Nem_3	296	301	PF02991	0.486
LIG_LIR_Nem_3	303	308	PF02991	0.539
LIG_LIR_Nem_3	62	67	PF02991	0.739
LIG_Pex14_2	276	280	PF04695	0.462
LIG_PTB_Apo_2	299	306	PF02174	0.502
LIG_PTB_Phospho_1	299	305	PF10480	0.498
LIG_SH2_PTP2	221	224	PF00017	0.472
LIG_SH2_STAP1	67	71	PF00017	0.641
LIG_SH2_STAT5	178	181	PF00017	0.482
LIG_SH2_STAT5	221	224	PF00017	0.472
LIG_SH2_STAT5	277	280	PF00017	0.453
LIG_SH2_STAT5	297	300	PF00017	0.229
LIG_SH2_STAT5	308	311	PF00017	0.529
LIG_SH3_1	155	161	PF00018	0.387
LIG_SH3_2	150	155	PF14604	0.538
LIG_SH3_2	158	163	PF14604	0.463
LIG_SH3_3	147	153	PF00018	0.522
LIG_SH3_3	155	161	PF00018	0.549
LIG_SH3_3	181	187	PF00018	0.548
LIG_SH3_3	48	54	PF00018	0.788
LIG_SUMO_SIM_par_1	225	231	PF11976	0.466
LIG_TRAF2_1	257	260	PF00917	0.556
LIG_TRFH_1	232	236	PF08558	0.584
LIG_TYR_ITIM	295	300	PF00017	0.437
LIG_UBA3_1	99	106	PF00899	0.446
LIG_WRC_WIRS_1	277	282	PF05994	0.443
LIG_WRC_WIRS_1	301	306	PF05994	0.289
MOD_CK1_1	12	18	PF00069	0.789
MOD_CK1_1	124	130	PF00069	0.537
MOD_CK1_1	94	100	PF00069	0.394
MOD_CK2_1	254	260	PF00069	0.583
MOD_CK2_1	268	274	PF00069	0.360
MOD_CK2_1	71	77	PF00069	0.615
MOD_Cter_Amidation	117	120	PF01082	0.642
MOD_GlcNHglycan	116	119	PF01048	0.637
MOD_GlcNHglycan	270	273	PF01048	0.552
MOD_GSK3_1	144	151	PF00069	0.481
MOD_GSK3_1	222	229	PF00069	0.428
MOD_GSK3_1	243	250	PF00069	0.531
MOD_GSK3_1	254	261	PF00069	0.613
MOD_GSK3_1	264	271	PF00069	0.311
MOD_GSK3_1	276	283	PF00069	0.325
MOD_GSK3_1	45	52	PF00069	0.729
MOD_GSK3_1	5	12	PF00069	0.711
MOD_N-GLC_1	210	215	PF02516	0.517
MOD_N-GLC_1	254	259	PF02516	0.530
MOD_NEK2_1	121	126	PF00069	0.711
MOD_NEK2_1	189	194	PF00069	0.499
MOD_NEK2_1	196	201	PF00069	0.515
MOD_NEK2_1	226	231	PF00069	0.443
MOD_NEK2_1	243	248	PF00069	0.533
MOD_NEK2_1	268	273	PF00069	0.536
MOD_NEK2_1	276	281	PF00069	0.425
MOD_NEK2_1	300	305	PF00069	0.501
MOD_NEK2_1	40	45	PF00069	0.723
MOD_NEK2_1	81	86	PF00069	0.705
MOD_NEK2_2	205	210	PF00069	0.296
MOD_PIKK_1	281	287	PF00454	0.482
MOD_PIKK_1	45	51	PF00454	0.707
MOD_PIKK_1	91	97	PF00454	0.377
MOD_Plk_1	203	209	PF00069	0.466
MOD_Plk_1	45	51	PF00069	0.707
MOD_Plk_1	81	87	PF00069	0.562
MOD_Plk_1	9	15	PF00069	0.544
MOD_Plk_4	121	127	PF00069	0.681
MOD_Plk_4	144	150	PF00069	0.540
MOD_Plk_4	205	211	PF00069	0.518
MOD_Plk_4	213	219	PF00069	0.521
MOD_Plk_4	222	228	PF00069	0.393
MOD_Plk_4	276	282	PF00069	0.451
MOD_Plk_4	300	306	PF00069	0.291
MOD_ProDKin_1	183	189	PF00069	0.523
MOD_ProDKin_1	5	11	PF00069	0.734
MOD_SUMO_rev_2	103	111	PF00179	0.605
TRG_DiLeu_BaLyEn_6	184	189	PF01217	0.545
TRG_DiLeu_BaLyEn_6	192	197	PF01217	0.484
TRG_ENDOCYTIC_2	221	224	PF00928	0.472
TRG_ENDOCYTIC_2	277	280	PF00928	0.453
TRG_ENDOCYTIC_2	297	300	PF00928	0.229
TRG_ENDOCYTIC_2	67	70	PF00928	0.587
TRG_ER_diArg_1	119	121	PF00400	0.700

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HT80	Leptomonas seymouri	57%	100%
A0A3Q8IFU1	Leishmania donovani	84%	100%
A4HIB7	Leishmania braziliensis	67%	100%
A4I5K1	Leishmania infantum	83%	100%
Q4Q7C0	Leishmania major	84%	100%