PSP1 C-terminal domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PSP1 C-terminal conserved region, putative

Species:

Leishmania mexicana

UniProt:

E9B0R6_LEIMU

TriTrypDb:

LmxM.29.1370

Length:

904

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0R6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0R6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	710	714	PF00656	0.665
CLV_NRD_NRD_1	235	237	PF00675	0.832
CLV_NRD_NRD_1	322	324	PF00675	0.703
CLV_NRD_NRD_1	497	499	PF00675	0.708
CLV_NRD_NRD_1	518	520	PF00675	0.583
CLV_NRD_NRD_1	577	579	PF00675	0.715
CLV_NRD_NRD_1	644	646	PF00675	0.720
CLV_NRD_NRD_1	794	796	PF00675	0.695
CLV_NRD_NRD_1	805	807	PF00675	0.509
CLV_PCSK_KEX2_1	234	236	PF00082	0.840
CLV_PCSK_KEX2_1	322	324	PF00082	0.703
CLV_PCSK_KEX2_1	497	499	PF00082	0.708
CLV_PCSK_KEX2_1	518	520	PF00082	0.583
CLV_PCSK_KEX2_1	577	579	PF00082	0.715
CLV_PCSK_KEX2_1	644	646	PF00082	0.720
CLV_PCSK_KEX2_1	723	725	PF00082	0.771
CLV_PCSK_KEX2_1	891	893	PF00082	0.538
CLV_PCSK_PC1ET2_1	723	725	PF00082	0.771
CLV_PCSK_PC1ET2_1	891	893	PF00082	0.538
CLV_PCSK_PC7_1	887	893	PF00082	0.450
CLV_PCSK_SKI1_1	22	26	PF00082	0.560
CLV_PCSK_SKI1_1	698	702	PF00082	0.695
CLV_PCSK_SKI1_1	737	741	PF00082	0.712
CLV_PCSK_SKI1_1	811	815	PF00082	0.511
CLV_PCSK_SKI1_1	825	829	PF00082	0.300
CLV_PCSK_SKI1_1	878	882	PF00082	0.448
CLV_PCSK_SKI1_1	887	891	PF00082	0.369
CLV_Separin_Metazoa	208	212	PF03568	0.629
DEG_APCC_DBOX_1	736	744	PF00400	0.706
DEG_SCF_FBW7_1	194	199	PF00400	0.665
DEG_SCF_FBW7_1	58	64	PF00400	0.535
DEG_SCF_FBW7_1	774	780	PF00400	0.634
DEG_SPOP_SBC_1	427	431	PF00917	0.762
DOC_CKS1_1	128	133	PF01111	0.799
DOC_CKS1_1	155	160	PF01111	0.755
DOC_CKS1_1	193	198	PF01111	0.641
DOC_CKS1_1	304	309	PF01111	0.811
DOC_CKS1_1	58	63	PF01111	0.761
DOC_CKS1_1	774	779	PF01111	0.629
DOC_CYCLIN_RxL_1	734	744	PF00134	0.769
DOC_CYCLIN_RxL_1	806	818	PF00134	0.394
DOC_CYCLIN_yCln2_LP_2	259	262	PF00134	0.717
DOC_CYCLIN_yCln2_LP_2	89	95	PF00134	0.808
DOC_MAPK_gen_1	577	587	PF00069	0.711
DOC_MAPK_gen_1	644	652	PF00069	0.529
DOC_MAPK_gen_1	795	801	PF00069	0.450
DOC_MAPK_gen_1	806	814	PF00069	0.450
DOC_MAPK_gen_1	825	834	PF00069	0.411
DOC_MAPK_MEF2A_6	160	168	PF00069	0.620
DOC_PP1_RVXF_1	876	883	PF00149	0.411
DOC_PP2B_LxvP_1	259	262	PF13499	0.717
DOC_PP2B_LxvP_1	288	291	PF13499	0.657
DOC_PP2B_LxvP_1	536	539	PF13499	0.748
DOC_PP2B_LxvP_1	93	96	PF13499	0.748
DOC_PP4_FxxP_1	176	179	PF00568	0.685
DOC_USP7_MATH_1	122	126	PF00917	0.765
DOC_USP7_MATH_1	134	138	PF00917	0.606
DOC_USP7_MATH_1	220	224	PF00917	0.740
DOC_USP7_MATH_1	230	234	PF00917	0.682
DOC_USP7_MATH_1	255	259	PF00917	0.706
DOC_USP7_MATH_1	315	319	PF00917	0.773
DOC_USP7_MATH_1	337	341	PF00917	0.736
DOC_USP7_MATH_1	370	374	PF00917	0.731
DOC_USP7_MATH_1	47	51	PF00917	0.601
DOC_USP7_MATH_1	508	512	PF00917	0.607
DOC_USP7_MATH_1	549	553	PF00917	0.729
DOC_USP7_MATH_1	61	65	PF00917	0.571
DOC_USP7_MATH_1	639	643	PF00917	0.663
DOC_USP7_MATH_1	667	671	PF00917	0.734
DOC_USP7_MATH_1	735	739	PF00917	0.629
DOC_USP7_MATH_1	777	781	PF00917	0.526
DOC_USP7_MATH_1	858	862	PF00917	0.462
DOC_USP7_MATH_1	871	875	PF00917	0.298
DOC_USP7_MATH_2	759	765	PF00917	0.635
DOC_WW_Pin1_4	127	132	PF00397	0.716
DOC_WW_Pin1_4	154	159	PF00397	0.703
DOC_WW_Pin1_4	175	180	PF00397	0.704
DOC_WW_Pin1_4	192	197	PF00397	0.686
DOC_WW_Pin1_4	215	220	PF00397	0.672
DOC_WW_Pin1_4	226	231	PF00397	0.725
DOC_WW_Pin1_4	27	32	PF00397	0.822
DOC_WW_Pin1_4	281	286	PF00397	0.712
DOC_WW_Pin1_4	303	308	PF00397	0.713
DOC_WW_Pin1_4	57	62	PF00397	0.712
DOC_WW_Pin1_4	69	74	PF00397	0.767
DOC_WW_Pin1_4	755	760	PF00397	0.612
DOC_WW_Pin1_4	773	778	PF00397	0.611
DOC_WW_Pin1_4	88	93	PF00397	0.562
LIG_14-3-3_CanoR_1	287	291	PF00244	0.820
LIG_14-3-3_CanoR_1	311	317	PF00244	0.751
LIG_14-3-3_CanoR_1	439	446	PF00244	0.664
LIG_14-3-3_CanoR_1	606	611	PF00244	0.826
LIG_14-3-3_CanoR_1	655	663	PF00244	0.720
LIG_14-3-3_CanoR_1	85	89	PF00244	0.758
LIG_14-3-3_CanoR_1	869	877	PF00244	0.522
LIG_Actin_WH2_2	782	797	PF00022	0.703
LIG_BIR_III_4	224	228	PF00653	0.665
LIG_BRCT_BRCA1_1	437	441	PF00533	0.698
LIG_BRCT_BRCA1_1	608	612	PF00533	0.541
LIG_EVH1_2	620	624	PF00568	0.499
LIG_FHA_1	197	203	PF00498	0.662
LIG_FHA_1	329	335	PF00498	0.709
LIG_FHA_1	64	70	PF00498	0.825
LIG_FHA_1	729	735	PF00498	0.759
LIG_FHA_1	816	822	PF00498	0.453
LIG_FHA_2	157	163	PF00498	0.709
LIG_FHA_2	345	351	PF00498	0.588
LIG_FHA_2	625	631	PF00498	0.733
LIG_FHA_2	70	76	PF00498	0.680
LIG_FHA_2	708	714	PF00498	0.710
LIG_HCF-1_HBM_1	475	478	PF13415	0.550
LIG_LIR_Apic_2	173	179	PF02991	0.686
LIG_LIR_Gen_1	622	633	PF02991	0.795
LIG_LIR_Gen_1	764	772	PF02991	0.625
LIG_LIR_Gen_1	779	789	PF02991	0.534
LIG_LIR_Gen_1	837	847	PF02991	0.394
LIG_LIR_Nem_3	195	200	PF02991	0.770
LIG_LIR_Nem_3	475	481	PF02991	0.593
LIG_LIR_Nem_3	622	628	PF02991	0.798
LIG_LIR_Nem_3	764	768	PF02991	0.632
LIG_LIR_Nem_3	779	785	PF02991	0.525
LIG_LIR_Nem_3	837	843	PF02991	0.352
LIG_LYPXL_yS_3	478	481	PF13949	0.526
LIG_PCNA_yPIPBox_3	203	211	PF02747	0.635
LIG_Pex14_2	168	172	PF04695	0.801
LIG_PTB_Apo_2	166	173	PF02174	0.687
LIG_Rb_LxCxE_1	736	758	PF01857	0.677
LIG_SH2_CRK	625	629	PF00017	0.629
LIG_SH2_CRK	782	786	PF00017	0.637
LIG_SH2_CRK	852	856	PF00017	0.411
LIG_SH2_NCK_1	461	465	PF00017	0.768
LIG_SH2_NCK_1	765	769	PF00017	0.715
LIG_SH2_SRC	765	768	PF00017	0.714
LIG_SH2_SRC	94	97	PF00017	0.748
LIG_SH2_STAP1	200	204	PF00017	0.686
LIG_SH2_STAP1	461	465	PF00017	0.730
LIG_SH2_STAP1	782	786	PF00017	0.699
LIG_SH2_STAT3	200	203	PF00017	0.754
LIG_SH2_STAT5	217	220	PF00017	0.495
LIG_SH2_STAT5	328	331	PF00017	0.713
LIG_SH2_STAT5	749	752	PF00017	0.531
LIG_SH2_STAT5	754	757	PF00017	0.574
LIG_SH2_STAT5	820	823	PF00017	0.407
LIG_SH2_STAT5	840	843	PF00017	0.183
LIG_SH3_3	272	278	PF00018	0.794
LIG_SH3_3	410	416	PF00018	0.774
LIG_SH3_3	568	574	PF00018	0.684
LIG_SH3_4	557	564	PF00018	0.537
LIG_SUMO_SIM_anti_2	684	690	PF11976	0.644
LIG_SUMO_SIM_par_1	526	533	PF11976	0.734
LIG_SUMO_SIM_par_1	583	588	PF11976	0.702
LIG_SUMO_SIM_par_1	664	670	PF11976	0.731
LIG_TRAF2_1	205	208	PF00917	0.615
LIG_TYR_ITIM	763	768	PF00017	0.599
LIG_TYR_ITIM	850	855	PF00017	0.411
LIG_WRC_WIRS_1	840	845	PF05994	0.352
LIG_WW_1	458	461	PF00397	0.702
MOD_CDK_SPxK_1	154	160	PF00069	0.649
MOD_CDK_SPxK_1	215	221	PF00069	0.675
MOD_CDK_SPxK_1	281	287	PF00069	0.715
MOD_CK1_1	123	129	PF00069	0.766
MOD_CK1_1	171	177	PF00069	0.704
MOD_CK1_1	223	229	PF00069	0.705
MOD_CK1_1	375	381	PF00069	0.581
MOD_CK1_1	426	432	PF00069	0.831
MOD_CK1_1	537	543	PF00069	0.644
MOD_CK1_1	623	629	PF00069	0.697
MOD_CK1_1	63	69	PF00069	0.839
MOD_CK1_1	657	663	PF00069	0.613
MOD_CK1_1	722	728	PF00069	0.665
MOD_CK1_1	861	867	PF00069	0.450
MOD_CK1_1	9	15	PF00069	0.716
MOD_CK2_1	171	177	PF00069	0.641
MOD_CK2_1	280	286	PF00069	0.600
MOD_CK2_1	295	301	PF00069	0.703
MOD_CK2_1	380	386	PF00069	0.808
MOD_CK2_1	624	630	PF00069	0.733
MOD_CK2_1	64	70	PF00069	0.781
MOD_CK2_1	755	761	PF00069	0.703
MOD_CK2_1	94	100	PF00069	0.529
MOD_Cter_Amidation	516	519	PF01082	0.621
MOD_GlcNHglycan	108	111	PF01048	0.762
MOD_GlcNHglycan	116	119	PF01048	0.783
MOD_GlcNHglycan	136	139	PF01048	0.573
MOD_GlcNHglycan	173	176	PF01048	0.704
MOD_GlcNHglycan	224	228	PF01048	0.753
MOD_GlcNHglycan	262	265	PF01048	0.703
MOD_GlcNHglycan	317	320	PF01048	0.669
MOD_GlcNHglycan	360	363	PF01048	0.666
MOD_GlcNHglycan	382	385	PF01048	0.704
MOD_GlcNHglycan	425	428	PF01048	0.760
MOD_GlcNHglycan	44	47	PF01048	0.839
MOD_GlcNHglycan	482	485	PF01048	0.679
MOD_GlcNHglycan	536	539	PF01048	0.670
MOD_GlcNHglycan	565	568	PF01048	0.800
MOD_GlcNHglycan	608	611	PF01048	0.822
MOD_GlcNHglycan	641	644	PF01048	0.671
MOD_GlcNHglycan	647	650	PF01048	0.718
MOD_GlcNHglycan	65	69	PF01048	0.738
MOD_GlcNHglycan	669	672	PF01048	0.631
MOD_GlcNHglycan	704	707	PF01048	0.535
MOD_GlcNHglycan	8	11	PF01048	0.829
MOD_GlcNHglycan	829	832	PF01048	0.460
MOD_GlcNHglycan	859	863	PF01048	0.392
MOD_GSK3_1	116	123	PF00069	0.786
MOD_GSK3_1	142	149	PF00069	0.737
MOD_GSK3_1	150	157	PF00069	0.689
MOD_GSK3_1	171	178	PF00069	0.776
MOD_GSK3_1	192	199	PF00069	0.634
MOD_GSK3_1	226	233	PF00069	0.740
MOD_GSK3_1	302	309	PF00069	0.712
MOD_GSK3_1	333	340	PF00069	0.610
MOD_GSK3_1	372	379	PF00069	0.740
MOD_GSK3_1	419	426	PF00069	0.788
MOD_GSK3_1	435	442	PF00069	0.556
MOD_GSK3_1	534	541	PF00069	0.758
MOD_GSK3_1	545	552	PF00069	0.681
MOD_GSK3_1	557	564	PF00069	0.629
MOD_GSK3_1	56	63	PF00069	0.822
MOD_GSK3_1	619	626	PF00069	0.747
MOD_GSK3_1	698	705	PF00069	0.556
MOD_GSK3_1	718	725	PF00069	0.572
MOD_GSK3_1	729	736	PF00069	0.749
MOD_GSK3_1	773	780	PF00069	0.535
MOD_GSK3_1	835	842	PF00069	0.400
MOD_GSK3_1	84	91	PF00069	0.765
MOD_GSK3_1	860	867	PF00069	0.434
MOD_GSK3_1	894	901	PF00069	0.741
MOD_LATS_1	604	610	PF00433	0.537
MOD_N-GLC_1	114	119	PF02516	0.840
MOD_N-GLC_1	168	173	PF02516	0.687
MOD_N-GLC_1	189	194	PF02516	0.516
MOD_N-GLC_1	337	342	PF02516	0.648
MOD_N-GLC_1	358	363	PF02516	0.565
MOD_N-GLC_1	376	381	PF02516	0.566
MOD_N-GLC_1	42	47	PF02516	0.805
MOD_N-GLC_1	701	706	PF02516	0.639
MOD_NEK2_1	25	30	PF00069	0.848
MOD_NEK2_1	280	285	PF00069	0.521
MOD_NEK2_1	563	568	PF00069	0.547
MOD_NEK2_1	624	629	PF00069	0.634
MOD_NEK2_1	719	724	PF00069	0.740
MOD_NEK2_1	814	819	PF00069	0.403
MOD_NEK2_1	827	832	PF00069	0.431
MOD_NEK2_1	843	848	PF00069	0.311
MOD_NEK2_1	894	899	PF00069	0.656
MOD_NEK2_2	777	782	PF00069	0.640
MOD_PIKK_1	116	122	PF00454	0.734
MOD_PIKK_1	189	195	PF00454	0.674
MOD_PIKK_1	372	378	PF00454	0.583
MOD_PIKK_1	48	54	PF00454	0.808
MOD_PIKK_1	487	493	PF00454	0.549
MOD_PIKK_1	557	563	PF00454	0.731
MOD_PIKK_1	898	904	PF00454	0.716
MOD_PKA_1	723	729	PF00069	0.778
MOD_PKA_2	106	112	PF00069	0.719
MOD_PKA_2	239	245	PF00069	0.653
MOD_PKA_2	286	292	PF00069	0.822
MOD_PKA_2	310	316	PF00069	0.753
MOD_PKA_2	48	54	PF00069	0.808
MOD_PKA_2	605	611	PF00069	0.535
MOD_PKA_2	654	660	PF00069	0.726
MOD_PKA_2	723	729	PF00069	0.778
MOD_PKA_2	78	84	PF00069	0.793
MOD_Plk_1	168	174	PF00069	0.715
MOD_Plk_1	189	195	PF00069	0.509
MOD_Plk_1	64	70	PF00069	0.653
MOD_Plk_2-3	761	767	PF00069	0.650
MOD_Plk_4	123	129	PF00069	0.821
MOD_Plk_4	255	261	PF00069	0.689
MOD_Plk_4	508	514	PF00069	0.587
MOD_Plk_4	620	626	PF00069	0.601
MOD_Plk_4	657	663	PF00069	0.605
MOD_Plk_4	729	735	PF00069	0.720
MOD_Plk_4	745	751	PF00069	0.520
MOD_Plk_4	777	783	PF00069	0.643
MOD_Plk_4	835	841	PF00069	0.411
MOD_Plk_4	84	90	PF00069	0.653
MOD_ProDKin_1	127	133	PF00069	0.715
MOD_ProDKin_1	154	160	PF00069	0.703
MOD_ProDKin_1	175	181	PF00069	0.703
MOD_ProDKin_1	192	198	PF00069	0.685
MOD_ProDKin_1	215	221	PF00069	0.675
MOD_ProDKin_1	226	232	PF00069	0.726
MOD_ProDKin_1	27	33	PF00069	0.823
MOD_ProDKin_1	281	287	PF00069	0.715
MOD_ProDKin_1	303	309	PF00069	0.712
MOD_ProDKin_1	57	63	PF00069	0.711
MOD_ProDKin_1	69	75	PF00069	0.765
MOD_ProDKin_1	755	761	PF00069	0.613
MOD_ProDKin_1	773	779	PF00069	0.609
MOD_ProDKin_1	88	94	PF00069	0.564
MOD_SUMO_rev_2	874	882	PF00179	0.450
TRG_DiLeu_BaEn_1	20	25	PF01217	0.781
TRG_DiLeu_BaLyEn_6	850	855	PF01217	0.434
TRG_ENDOCYTIC_2	253	256	PF00928	0.693
TRG_ENDOCYTIC_2	478	481	PF00928	0.526
TRG_ENDOCYTIC_2	625	628	PF00928	0.633
TRG_ENDOCYTIC_2	765	768	PF00928	0.627
TRG_ENDOCYTIC_2	782	785	PF00928	0.503
TRG_ENDOCYTIC_2	840	843	PF00928	0.387
TRG_ENDOCYTIC_2	852	855	PF00928	0.411
TRG_ER_diArg_1	152	155	PF00400	0.777
TRG_ER_diArg_1	234	236	PF00400	0.779
TRG_ER_diArg_1	321	323	PF00400	0.700
TRG_ER_diArg_1	518	520	PF00400	0.583
TRG_ER_diArg_1	576	578	PF00400	0.717
TRG_ER_diArg_1	644	646	PF00400	0.720
TRG_ER_diArg_1	77	80	PF00400	0.830
TRG_Pf-PMV_PEXEL_1	811	815	PF00026	0.411

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IA65	Leptomonas seymouri	43%	90%
A0A3S7X3A5	Leishmania donovani	87%	99%
A4HI89	Leishmania braziliensis	67%	98%
A4I5G8	Leishmania infantum	87%	85%
Q4Q7G7	Leishmania major	86%	99%