N-acetyltransferase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0Q5_LEIMU

TriTrypDb:

LmxM.29.1255

Length:

351

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0Q5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0Q5

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	3
GO:0016407	acetyltransferase activity	5	2
GO:0016740	transferase activity	2	3
GO:0016746	acyltransferase activity	3	2
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	251	255	PF00656	0.517
CLV_C14_Caspase3-7	29	33	PF00656	0.518
CLV_NRD_NRD_1	103	105	PF00675	0.547
CLV_NRD_NRD_1	184	186	PF00675	0.655
CLV_NRD_NRD_1	226	228	PF00675	0.428
CLV_NRD_NRD_1	252	254	PF00675	0.485
CLV_NRD_NRD_1	272	274	PF00675	0.531
CLV_NRD_NRD_1	323	325	PF00675	0.346
CLV_NRD_NRD_1	330	332	PF00675	0.405
CLV_PCSK_KEX2_1	184	186	PF00082	0.655
CLV_PCSK_KEX2_1	225	227	PF00082	0.436
CLV_PCSK_KEX2_1	252	254	PF00082	0.485
CLV_PCSK_KEX2_1	272	274	PF00082	0.520
CLV_PCSK_KEX2_1	276	278	PF00082	0.571
CLV_PCSK_KEX2_1	323	325	PF00082	0.399
CLV_PCSK_KEX2_1	330	332	PF00082	0.438
CLV_PCSK_PC1ET2_1	276	278	PF00082	0.589
CLV_PCSK_PC7_1	272	278	PF00082	0.627
CLV_PCSK_SKI1_1	273	277	PF00082	0.605
CLV_TASPASE1	65	71	PF01112	0.507
DEG_APCC_DBOX_1	261	269	PF00400	0.427
DEG_APCC_DBOX_1	81	89	PF00400	0.391
DEG_Nend_UBRbox_1	1	4	PF02207	0.611
DOC_CYCLIN_RxL_1	320	329	PF00134	0.376
DOC_CYCLIN_yCln2_LP_2	53	59	PF00134	0.542
DOC_MAPK_gen_1	79	88	PF00069	0.376
DOC_PP1_RVXF_1	321	328	PF00149	0.367
DOC_PP2B_LxvP_1	53	56	PF13499	0.551
DOC_USP7_MATH_1	10	14	PF00917	0.496
DOC_USP7_MATH_1	137	141	PF00917	0.523
DOC_USP7_MATH_1	39	43	PF00917	0.675
DOC_USP7_MATH_1	78	82	PF00917	0.444
DOC_WW_Pin1_4	172	177	PF00397	0.685
DOC_WW_Pin1_4	183	188	PF00397	0.568
DOC_WW_Pin1_4	198	203	PF00397	0.484
DOC_WW_Pin1_4	43	48	PF00397	0.538
LIG_14-3-3_CanoR_1	104	110	PF00244	0.585
LIG_14-3-3_CanoR_1	170	176	PF00244	0.680
LIG_14-3-3_CanoR_1	227	233	PF00244	0.366
LIG_14-3-3_CanoR_1	264	269	PF00244	0.258
LIG_14-3-3_CanoR_1	272	278	PF00244	0.454
LIG_14-3-3_CanoR_1	282	286	PF00244	0.468
LIG_deltaCOP1_diTrp_1	69	74	PF00928	0.459
LIG_FHA_1	176	182	PF00498	0.558
LIG_FHA_1	233	239	PF00498	0.549
LIG_FHA_1	9	15	PF00498	0.557
LIG_LIR_Gen_1	177	187	PF02991	0.542
LIG_LIR_Gen_1	212	222	PF02991	0.373
LIG_LIR_Gen_1	58	66	PF02991	0.466
LIG_LIR_Nem_3	177	182	PF02991	0.537
LIG_LIR_Nem_3	212	217	PF02991	0.400
LIG_LIR_Nem_3	320	325	PF02991	0.354
LIG_LIR_Nem_3	58	62	PF02991	0.406
LIG_LIR_Nem_3	71	77	PF02991	0.443
LIG_PDZ_Class_2	346	351	PF00595	0.346
LIG_Rb_LxCxE_1	235	254	PF01857	0.478
LIG_SH2_CRK	179	183	PF00017	0.544
LIG_SH2_CRK	322	326	PF00017	0.421
LIG_SH2_NCK_1	179	183	PF00017	0.544
LIG_SH2_PTP2	214	217	PF00017	0.436
LIG_SH2_SRC	59	62	PF00017	0.466
LIG_SH2_STAT5	21	24	PF00017	0.439
LIG_SH2_STAT5	214	217	PF00017	0.402
LIG_SH2_STAT5	258	261	PF00017	0.330
LIG_SH2_STAT5	332	335	PF00017	0.531
LIG_SH2_STAT5	59	62	PF00017	0.466
LIG_SH3_3	216	222	PF00018	0.474
LIG_SH3_3	288	294	PF00018	0.487
LIG_SH3_3	41	47	PF00018	0.516
LIG_SUMO_SIM_anti_2	342	348	PF11976	0.344
LIG_SUMO_SIM_anti_2	58	64	PF11976	0.470
LIG_TRAF2_1	129	132	PF00917	0.599
LIG_TYR_ITIM	57	62	PF00017	0.408
MOD_CDK_SPxxK_3	43	50	PF00069	0.495
MOD_CK1_1	121	127	PF00069	0.654
MOD_CK1_1	148	154	PF00069	0.564
MOD_CK1_1	172	178	PF00069	0.699
MOD_CK1_1	180	186	PF00069	0.582
MOD_CK1_1	193	199	PF00069	0.626
MOD_CK1_1	42	48	PF00069	0.663
MOD_CK2_1	126	132	PF00069	0.674
MOD_CK2_1	303	309	PF00069	0.745
MOD_GlcNHglycan	122	126	PF01048	0.656
MOD_GlcNHglycan	128	131	PF01048	0.583
MOD_GlcNHglycan	147	150	PF01048	0.558
MOD_GlcNHglycan	153	156	PF01048	0.515
MOD_GlcNHglycan	171	174	PF01048	0.406
MOD_GlcNHglycan	188	191	PF01048	0.500
MOD_GlcNHglycan	192	195	PF01048	0.641
MOD_GlcNHglycan	41	44	PF01048	0.675
MOD_GSK3_1	100	107	PF00069	0.712
MOD_GSK3_1	109	116	PF00069	0.593
MOD_GSK3_1	147	154	PF00069	0.488
MOD_GSK3_1	186	193	PF00069	0.709
MOD_GSK3_1	228	235	PF00069	0.427
MOD_GSK3_1	264	271	PF00069	0.515
MOD_GSK3_1	39	46	PF00069	0.672
MOD_GSK3_1	6	13	PF00069	0.574
MOD_NEK2_1	268	273	PF00069	0.472
MOD_NEK2_2	16	21	PF00069	0.449
MOD_NEK2_2	317	322	PF00069	0.265
MOD_OFUCOSY	147	152	PF10250	0.573
MOD_PIKK_1	232	238	PF00454	0.373
MOD_PKA_1	104	110	PF00069	0.513
MOD_PKA_2	137	143	PF00069	0.512
MOD_PKA_2	169	175	PF00069	0.532
MOD_PKA_2	271	277	PF00069	0.447
MOD_PKA_2	281	287	PF00069	0.481
MOD_PKA_2	78	84	PF00069	0.439
MOD_PKB_1	262	270	PF00069	0.265
MOD_Plk_1	70	76	PF00069	0.449
MOD_Plk_4	177	183	PF00069	0.637
MOD_Plk_4	228	234	PF00069	0.397
MOD_Plk_4	317	323	PF00069	0.270
MOD_Plk_4	55	61	PF00069	0.509
MOD_ProDKin_1	172	178	PF00069	0.692
MOD_ProDKin_1	183	189	PF00069	0.570
MOD_ProDKin_1	198	204	PF00069	0.481
MOD_ProDKin_1	43	49	PF00069	0.535
TRG_ENDOCYTIC_2	179	182	PF00928	0.543
TRG_ENDOCYTIC_2	214	217	PF00928	0.417
TRG_ENDOCYTIC_2	322	325	PF00928	0.418
TRG_ENDOCYTIC_2	59	62	PF00928	0.402
TRG_ER_diArg_1	224	227	PF00400	0.419
TRG_ER_diArg_1	322	324	PF00400	0.373
TRG_ER_diArg_1	330	332	PF00400	0.407
TRG_NES_CRM1_1	52	65	PF08389	0.476

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8W0	Leptomonas seymouri	44%	100%
A0A3S7X392	Leishmania donovani	86%	100%
A4HI78	Leishmania braziliensis	70%	100%
A4I5F7	Leishmania infantum	86%	100%
Q4Q7H8	Leishmania major	86%	100%