Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0P2_LEIMU

TriTrypDb:

LmxM.29.1130

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

E9B0P2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0P2

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	88	90	PF00675	0.624
CLV_NRD_NRD_1	9	11	PF00675	0.391
CLV_PCSK_KEX2_1	46	48	PF00082	0.594
CLV_PCSK_KEX2_1	70	72	PF00082	0.617
CLV_PCSK_KEX2_1	88	90	PF00082	0.623
CLV_PCSK_PC1ET2_1	46	48	PF00082	0.594
CLV_PCSK_PC1ET2_1	70	72	PF00082	0.617
CLV_PCSK_SKI1_1	57	61	PF00082	0.659
DEG_APCC_DBOX_1	70	78	PF00400	0.428
DOC_USP7_MATH_1	75	79	PF00917	0.454

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMI3	Leptomonas seymouri	80%	100%
A0A3Q8IEQ3	Leishmania donovani	95%	100%
A0A422P532	Trypanosoma rangeli	56%	80%
A4HI67	Leishmania braziliensis	90%	100%
A4I5E4	Leishmania infantum	95%	100%
C9ZQS9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	99%
Q4Q7J0	Leishmania major	91%	100%

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