LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B0P2_LEIMU
TriTrypDb:
LmxM.29.1130
Length:
94

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
Term Name Level Count
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6

Expansion

Sequence features

E9B0P2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0P2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 88 90 PF00675 0.624
CLV_NRD_NRD_1 9 11 PF00675 0.391
CLV_PCSK_KEX2_1 46 48 PF00082 0.594
CLV_PCSK_KEX2_1 70 72 PF00082 0.617
CLV_PCSK_KEX2_1 88 90 PF00082 0.623
CLV_PCSK_PC1ET2_1 46 48 PF00082 0.594
CLV_PCSK_PC1ET2_1 70 72 PF00082 0.617
CLV_PCSK_SKI1_1 57 61 PF00082 0.659
DEG_APCC_DBOX_1 70 78 PF00400 0.428
DOC_USP7_MATH_1 75 79 PF00917 0.454
LIG_14-3-3_CanoR_1 10 16 PF00244 0.588
LIG_14-3-3_CanoR_1 57 66 PF00244 0.468
LIG_BIR_II_1 1 5 PF00653 0.656
LIG_BRCT_BRCA1_1 22 26 PF00533 0.598
LIG_EH1_1 2 10 PF00400 0.688
LIG_LIR_Gen_1 78 87 PF02991 0.418
LIG_LIR_Nem_3 23 29 PF02991 0.514
LIG_LIR_Nem_3 38 42 PF02991 0.259
LIG_SH2_CRK 29 33 PF00017 0.438
LIG_SH2_CRK 45 49 PF00017 0.389
LIG_SH2_STAP1 55 59 PF00017 0.462
LIG_SH2_STAT5 58 61 PF00017 0.439
LIG_SH3_1 47 53 PF00018 0.407
LIG_SH3_3 47 53 PF00018 0.407
LIG_UBA3_1 5 11 PF00899 0.530
LIG_WRC_WIRS_1 12 17 PF05994 0.586
MOD_CK1_1 20 26 PF00069 0.562
MOD_GSK3_1 11 18 PF00069 0.688
MOD_NEK2_1 15 20 PF00069 0.589
MOD_NEK2_1 83 88 PF00069 0.335
MOD_Plk_1 75 81 PF00069 0.453
MOD_SUMO_for_1 53 56 PF00179 0.502
TRG_DiLeu_BaEn_3 61 67 PF01217 0.475
TRG_ENDOCYTIC_2 29 32 PF00928 0.348
TRG_ENDOCYTIC_2 45 48 PF00928 0.391
TRG_ENDOCYTIC_2 80 83 PF00928 0.390
TRG_ER_diArg_1 87 89 PF00400 0.418
TRG_Pf-PMV_PEXEL_1 57 61 PF00026 0.674

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IMI3 Leptomonas seymouri 80% 100%
A0A3Q8IEQ3 Leishmania donovani 95% 100%
A0A422P532 Trypanosoma rangeli 56% 80%
A4HI67 Leishmania braziliensis 90% 100%
A4I5E4 Leishmania infantum 95% 100%
C9ZQS9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 59% 99%
Q4Q7J0 Leishmania major 91% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS