Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0L9_LEIMU

TriTrypDb:

LmxM.29.0900

Length:

619

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0L9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0L9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	109	111	PF00675	0.603
CLV_NRD_NRD_1	339	341	PF00675	0.830
CLV_NRD_NRD_1	387	389	PF00675	0.688
CLV_NRD_NRD_1	415	417	PF00675	0.620
CLV_NRD_NRD_1	418	420	PF00675	0.642
CLV_NRD_NRD_1	432	434	PF00675	0.592
CLV_NRD_NRD_1	482	484	PF00675	0.741
CLV_NRD_NRD_1	95	97	PF00675	0.665
CLV_PCSK_FUR_1	416	420	PF00082	0.541
CLV_PCSK_FUR_1	93	97	PF00082	0.509
CLV_PCSK_KEX2_1	108	110	PF00082	0.611
CLV_PCSK_KEX2_1	155	157	PF00082	0.434
CLV_PCSK_KEX2_1	174	176	PF00082	0.441
CLV_PCSK_KEX2_1	339	341	PF00082	0.830
CLV_PCSK_KEX2_1	387	389	PF00082	0.629
CLV_PCSK_KEX2_1	415	417	PF00082	0.620
CLV_PCSK_KEX2_1	418	420	PF00082	0.642
CLV_PCSK_KEX2_1	432	434	PF00082	0.592
CLV_PCSK_KEX2_1	482	484	PF00082	0.651
CLV_PCSK_KEX2_1	95	97	PF00082	0.656
CLV_PCSK_PC1ET2_1	155	157	PF00082	0.434
CLV_PCSK_PC1ET2_1	174	176	PF00082	0.441
CLV_PCSK_SKI1_1	119	123	PF00082	0.588
CLV_PCSK_SKI1_1	201	205	PF00082	0.490
CLV_PCSK_SKI1_1	222	226	PF00082	0.409
CLV_PCSK_SKI1_1	324	328	PF00082	0.727
CLV_PCSK_SKI1_1	448	452	PF00082	0.619
CLV_PCSK_SKI1_1	548	552	PF00082	0.630
CLV_PCSK_SKI1_1	563	567	PF00082	0.404
CLV_PCSK_SKI1_1	574	578	PF00082	0.438
CLV_Separin_Metazoa	40	44	PF03568	0.643
DEG_APCC_DBOX_1	200	208	PF00400	0.437
DEG_APCC_DBOX_1	562	570	PF00400	0.535
DEG_Nend_UBRbox_2	1	3	PF02207	0.661
DEG_SCF_FBW7_1	363	369	PF00400	0.673
DEG_SPOP_SBC_1	334	338	PF00917	0.532
DOC_CDC14_PxL_1	497	505	PF14671	0.499
DOC_CKS1_1	325	330	PF01111	0.677
DOC_CKS1_1	363	368	PF01111	0.670
DOC_CYCLIN_RxL_1	210	223	PF00134	0.362
DOC_CYCLIN_RxL_1	558	570	PF00134	0.545
DOC_MAPK_gen_1	268	277	PF00069	0.533
DOC_MAPK_gen_1	445	453	PF00069	0.553
DOC_MAPK_gen_1	93	100	PF00069	0.738
DOC_PP1_RVXF_1	214	221	PF00149	0.439
DOC_USP7_MATH_1	146	150	PF00917	0.471
DOC_USP7_MATH_1	186	190	PF00917	0.386
DOC_USP7_MATH_1	234	238	PF00917	0.642
DOC_USP7_MATH_1	293	297	PF00917	0.685
DOC_USP7_MATH_1	311	315	PF00917	0.543
DOC_USP7_MATH_1	335	339	PF00917	0.674
DOC_USP7_MATH_1	344	348	PF00917	0.601
DOC_USP7_MATH_1	395	399	PF00917	0.577
DOC_USP7_MATH_1	404	408	PF00917	0.631
DOC_USP7_MATH_1	460	464	PF00917	0.671
DOC_USP7_MATH_1	91	95	PF00917	0.691
DOC_USP7_UBL2_3	236	240	PF12436	0.596
DOC_WW_Pin1_4	1	6	PF00397	0.682
DOC_WW_Pin1_4	111	116	PF00397	0.675
DOC_WW_Pin1_4	133	138	PF00397	0.656
DOC_WW_Pin1_4	142	147	PF00397	0.661
DOC_WW_Pin1_4	289	294	PF00397	0.640
DOC_WW_Pin1_4	305	310	PF00397	0.573
DOC_WW_Pin1_4	324	329	PF00397	0.624
DOC_WW_Pin1_4	362	367	PF00397	0.675
DOC_WW_Pin1_4	369	374	PF00397	0.637
DOC_WW_Pin1_4	431	436	PF00397	0.559
DOC_WW_Pin1_4	456	461	PF00397	0.647
DOC_WW_Pin1_4	470	475	PF00397	0.609
DOC_WW_Pin1_4	476	481	PF00397	0.601
DOC_WW_Pin1_4	483	488	PF00397	0.795
DOC_WW_Pin1_4	537	542	PF00397	0.769
DOC_WW_Pin1_4	548	553	PF00397	0.578
DOC_WW_Pin1_4	63	68	PF00397	0.703
LIG_14-3-3_CanoR_1	109	115	PF00244	0.611
LIG_14-3-3_CanoR_1	119	128	PF00244	0.686
LIG_14-3-3_CanoR_1	175	179	PF00244	0.390
LIG_14-3-3_CanoR_1	252	258	PF00244	0.385
LIG_14-3-3_CanoR_1	299	309	PF00244	0.619
LIG_14-3-3_CanoR_1	394	403	PF00244	0.691
LIG_14-3-3_CanoR_1	433	443	PF00244	0.739
LIG_14-3-3_CanoR_1	482	486	PF00244	0.653
LIG_14-3-3_CanoR_1	522	528	PF00244	0.700
LIG_14-3-3_CanoR_1	536	541	PF00244	0.542
LIG_Actin_WH2_2	604	619	PF00022	0.459
LIG_APCC_ABBA_1	451	456	PF00400	0.631
LIG_Clathr_ClatBox_1	16	20	PF01394	0.529
LIG_CSL_BTD_1	143	146	PF09270	0.491
LIG_FHA_1	112	118	PF00498	0.679
LIG_FHA_1	164	170	PF00498	0.457
LIG_FHA_1	270	276	PF00498	0.347
LIG_FHA_1	494	500	PF00498	0.531
LIG_FHA_2	148	154	PF00498	0.511
LIG_FHA_2	254	260	PF00498	0.391
LIG_FHA_2	35	41	PF00498	0.644
LIG_FHA_2	502	508	PF00498	0.493
LIG_LIR_Apic_2	537	541	PF02991	0.625
LIG_LIR_Nem_3	141	147	PF02991	0.499
LIG_LIR_Nem_3	251	257	PF02991	0.467
LIG_LIR_Nem_3	473	478	PF02991	0.636
LIG_LRP6_Inhibitor_1	262	268	PF00058	0.453
LIG_SH2_CRK	475	479	PF00017	0.728
LIG_SH2_CRK	538	542	PF00017	0.623
LIG_SH2_SRC	157	160	PF00017	0.477
LIG_SH2_STAP1	572	576	PF00017	0.486
LIG_SH2_STAT3	214	217	PF00017	0.500
LIG_SH2_STAT3	469	472	PF00017	0.723
LIG_SH2_STAT3	595	598	PF00017	0.366
LIG_SH2_STAT5	157	160	PF00017	0.418
LIG_SH2_STAT5	214	217	PF00017	0.500
LIG_SH2_STAT5	249	252	PF00017	0.378
LIG_SH2_STAT5	255	258	PF00017	0.369
LIG_SH2_STAT5	604	607	PF00017	0.384
LIG_SH3_1	192	198	PF00018	0.589
LIG_SH3_3	134	140	PF00018	0.641
LIG_SH3_3	192	198	PF00018	0.589
LIG_SH3_3	21	27	PF00018	0.514
LIG_SH3_3	3	9	PF00018	0.723
LIG_SH3_3	322	328	PF00018	0.676
LIG_SH3_3	360	366	PF00018	0.658
LIG_SH3_3	389	395	PF00018	0.594
LIG_SH3_3	397	403	PF00018	0.612
LIG_TRAF2_1	139	142	PF00917	0.662
LIG_TRAF2_1	149	152	PF00917	0.418
LIG_TRAF2_1	261	264	PF00917	0.495
LIG_UBA3_1	565	574	PF00899	0.531
LIG_WW_3	40	44	PF00397	0.697
MOD_CDC14_SPxK_1	479	482	PF00782	0.644
MOD_CDK_SPK_2	324	329	PF00069	0.637
MOD_CDK_SPK_2	537	542	PF00069	0.769
MOD_CDK_SPxK_1	476	482	PF00069	0.645
MOD_CDK_SPxxK_3	305	312	PF00069	0.531
MOD_CDK_SPxxK_3	371	378	PF00069	0.599
MOD_CDK_SPxxK_3	470	477	PF00069	0.707
MOD_CK1_1	120	126	PF00069	0.643
MOD_CK1_1	258	264	PF00069	0.407
MOD_CK1_1	285	291	PF00069	0.682
MOD_CK1_1	305	311	PF00069	0.653
MOD_CK1_1	319	325	PF00069	0.602
MOD_CK1_1	343	349	PF00069	0.683
MOD_CK1_1	4	10	PF00069	0.523
MOD_CK1_1	407	413	PF00069	0.628
MOD_CK1_1	431	437	PF00069	0.565
MOD_CK1_1	46	52	PF00069	0.606
MOD_CK1_1	486	492	PF00069	0.526
MOD_CK1_1	516	522	PF00069	0.674
MOD_CK2_1	146	152	PF00069	0.497
MOD_CK2_1	174	180	PF00069	0.382
MOD_CK2_1	258	264	PF00069	0.437
MOD_CK2_1	34	40	PF00069	0.726
MOD_GlcNHglycan	102	105	PF01048	0.649
MOD_GlcNHglycan	119	122	PF01048	0.602
MOD_GlcNHglycan	133	136	PF01048	0.539
MOD_GlcNHglycan	188	191	PF01048	0.399
MOD_GlcNHglycan	236	239	PF01048	0.583
MOD_GlcNHglycan	296	299	PF01048	0.627
MOD_GlcNHglycan	309	312	PF01048	0.710
MOD_GlcNHglycan	342	345	PF01048	0.666
MOD_GlcNHglycan	346	349	PF01048	0.685
MOD_GlcNHglycan	351	354	PF01048	0.787
MOD_GlcNHglycan	406	409	PF01048	0.642
MOD_GlcNHglycan	423	426	PF01048	0.586
MOD_GlcNHglycan	436	439	PF01048	0.533
MOD_GlcNHglycan	488	491	PF01048	0.550
MOD_GlcNHglycan	511	514	PF01048	0.655
MOD_GlcNHglycan	523	526	PF01048	0.508
MOD_GlcNHglycan	58	61	PF01048	0.683
MOD_GlcNHglycan	89	92	PF01048	0.553
MOD_GSK3_1	111	118	PF00069	0.770
MOD_GSK3_1	142	149	PF00069	0.675
MOD_GSK3_1	285	292	PF00069	0.611
MOD_GSK3_1	30	37	PF00069	0.705
MOD_GSK3_1	307	314	PF00069	0.814
MOD_GSK3_1	316	323	PF00069	0.752
MOD_GSK3_1	340	347	PF00069	0.557
MOD_GSK3_1	362	369	PF00069	0.551
MOD_GSK3_1	421	428	PF00069	0.679
MOD_GSK3_1	456	463	PF00069	0.767
MOD_GSK3_1	489	496	PF00069	0.651
MOD_GSK3_1	509	516	PF00069	0.591
MOD_GSK3_1	537	544	PF00069	0.644
MOD_GSK3_1	87	94	PF00069	0.593
MOD_N-GLC_1	34	39	PF02516	0.695
MOD_N-GLC_1	369	374	PF02516	0.694
MOD_N-GLC_1	493	498	PF02516	0.576
MOD_N-GLC_1	574	579	PF02516	0.353
MOD_N-GLC_1	74	79	PF02516	0.809
MOD_NEK2_1	100	105	PF00069	0.674
MOD_NEK2_1	117	122	PF00069	0.528
MOD_NEK2_1	220	225	PF00069	0.415
MOD_NEK2_1	253	258	PF00069	0.459
MOD_NEK2_1	269	274	PF00069	0.469
MOD_NEK2_1	282	287	PF00069	0.511
MOD_NEK2_1	34	39	PF00069	0.546
MOD_NEK2_1	493	498	PF00069	0.643
MOD_NEK2_1	520	525	PF00069	0.655
MOD_PIKK_1	122	128	PF00454	0.578
MOD_PIKK_1	147	153	PF00454	0.502
MOD_PIKK_1	4	10	PF00454	0.523
MOD_PIKK_1	468	474	PF00454	0.686
MOD_PIKK_1	53	59	PF00454	0.672
MOD_PK_1	174	180	PF00069	0.426
MOD_PKA_1	174	180	PF00069	0.426
MOD_PKA_2	174	180	PF00069	0.382
MOD_PKA_2	269	275	PF00069	0.480
MOD_PKA_2	311	317	PF00069	0.686
MOD_PKA_2	319	325	PF00069	0.558
MOD_PKA_2	481	487	PF00069	0.633
MOD_PKA_2	521	527	PF00069	0.717
MOD_PKA_2	541	547	PF00069	0.530
MOD_PKB_1	108	116	PF00069	0.614
MOD_Plk_1	258	264	PF00069	0.401
MOD_Plk_1	493	499	PF00069	0.658
MOD_Plk_1	574	580	PF00069	0.350
MOD_Plk_4	164	170	PF00069	0.428
MOD_Plk_4	210	216	PF00069	0.402
MOD_Plk_4	220	226	PF00069	0.535
MOD_Plk_4	381	387	PF00069	0.685
MOD_ProDKin_1	1	7	PF00069	0.679
MOD_ProDKin_1	111	117	PF00069	0.676
MOD_ProDKin_1	133	139	PF00069	0.653
MOD_ProDKin_1	142	148	PF00069	0.648
MOD_ProDKin_1	289	295	PF00069	0.639
MOD_ProDKin_1	305	311	PF00069	0.573
MOD_ProDKin_1	324	330	PF00069	0.625
MOD_ProDKin_1	362	368	PF00069	0.676
MOD_ProDKin_1	369	375	PF00069	0.632
MOD_ProDKin_1	431	437	PF00069	0.553
MOD_ProDKin_1	456	462	PF00069	0.646
MOD_ProDKin_1	470	476	PF00069	0.610
MOD_ProDKin_1	483	489	PF00069	0.795
MOD_ProDKin_1	537	543	PF00069	0.765
MOD_ProDKin_1	548	554	PF00069	0.575
MOD_ProDKin_1	63	69	PF00069	0.704
MOD_SUMO_rev_2	237	245	PF00179	0.483
TRG_ENDOCYTIC_2	254	257	PF00928	0.487
TRG_ENDOCYTIC_2	475	478	PF00928	0.640
TRG_ER_diArg_1	108	110	PF00400	0.584
TRG_ER_diArg_1	267	270	PF00400	0.458
TRG_ER_diArg_1	339	342	PF00400	0.675
TRG_ER_diArg_1	386	388	PF00400	0.695
TRG_ER_diArg_1	414	416	PF00400	0.626
TRG_ER_diArg_1	417	419	PF00400	0.632
TRG_ER_diArg_1	560	563	PF00400	0.565
TRG_ER_diArg_1	93	96	PF00400	0.711
TRG_Pf-PMV_PEXEL_1	563	567	PF00026	0.535

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8T3	Leptomonas seymouri	41%	93%
A0A3Q8IE52	Leishmania donovani	84%	90%
A4HI45	Leishmania braziliensis	55%	100%
A4I5C1	Leishmania infantum	84%	90%
Q4Q7L3	Leishmania major	84%	100%