Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0L1_LEIMU

TriTrypDb:

LmxM.29.0820

Length:

771

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0L1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0L1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	167	171	PF00656	0.387
CLV_C14_Caspase3-7	22	26	PF00656	0.509
CLV_C14_Caspase3-7	32	36	PF00656	0.483
CLV_C14_Caspase3-7	380	384	PF00656	0.478
CLV_C14_Caspase3-7	620	624	PF00656	0.606
CLV_NRD_NRD_1	114	116	PF00675	0.464
CLV_NRD_NRD_1	130	132	PF00675	0.437
CLV_NRD_NRD_1	163	165	PF00675	0.484
CLV_NRD_NRD_1	180	182	PF00675	0.576
CLV_NRD_NRD_1	215	217	PF00675	0.485
CLV_NRD_NRD_1	232	234	PF00675	0.454
CLV_NRD_NRD_1	465	467	PF00675	0.585
CLV_NRD_NRD_1	656	658	PF00675	0.616
CLV_NRD_NRD_1	681	683	PF00675	0.741
CLV_NRD_NRD_1	741	743	PF00675	0.507
CLV_PCSK_FUR_1	178	182	PF00082	0.479
CLV_PCSK_KEX2_1	113	115	PF00082	0.430
CLV_PCSK_KEX2_1	130	132	PF00082	0.419
CLV_PCSK_KEX2_1	162	164	PF00082	0.482
CLV_PCSK_KEX2_1	180	182	PF00082	0.350
CLV_PCSK_KEX2_1	215	217	PF00082	0.485
CLV_PCSK_KEX2_1	231	233	PF00082	0.453
CLV_PCSK_KEX2_1	285	287	PF00082	0.625
CLV_PCSK_KEX2_1	465	467	PF00082	0.585
CLV_PCSK_KEX2_1	656	658	PF00082	0.616
CLV_PCSK_KEX2_1	680	682	PF00082	0.735
CLV_PCSK_KEX2_1	706	708	PF00082	0.677
CLV_PCSK_PC1ET2_1	231	233	PF00082	0.453
CLV_PCSK_PC1ET2_1	285	287	PF00082	0.544
CLV_PCSK_PC1ET2_1	706	708	PF00082	0.677
CLV_PCSK_PC7_1	159	165	PF00082	0.511
CLV_PCSK_SKI1_1	103	107	PF00082	0.495
CLV_PCSK_SKI1_1	147	151	PF00082	0.456
CLV_PCSK_SKI1_1	180	184	PF00082	0.504
CLV_PCSK_SKI1_1	425	429	PF00082	0.413
CLV_PCSK_SKI1_1	570	574	PF00082	0.490
CLV_Separin_Metazoa	175	179	PF03568	0.507
DEG_APCC_DBOX_1	102	110	PF00400	0.492
DEG_APCC_DBOX_1	179	187	PF00400	0.506
DEG_APCC_DBOX_1	424	432	PF00400	0.406
DEG_SPOP_SBC_1	613	617	PF00917	0.611
DEG_SPOP_SBC_1	712	716	PF00917	0.578
DOC_CKS1_1	683	688	PF01111	0.677
DOC_CYCLIN_RxL_1	144	152	PF00134	0.502
DOC_CYCLIN_yCln2_LP_2	333	339	PF00134	0.555
DOC_MAPK_gen_1	113	123	PF00069	0.485
DOC_MAPK_gen_1	130	136	PF00069	0.489
DOC_MAPK_MEF2A_6	245	252	PF00069	0.385
DOC_PP1_RVXF_1	532	539	PF00149	0.437
DOC_PP4_FxxP_1	337	340	PF00568	0.481
DOC_USP7_MATH_1	320	324	PF00917	0.505
DOC_USP7_MATH_1	328	332	PF00917	0.445
DOC_USP7_MATH_1	525	529	PF00917	0.461
DOC_USP7_MATH_1	6	10	PF00917	0.566
DOC_USP7_MATH_1	613	617	PF00917	0.749
DOC_USP7_MATH_1	652	656	PF00917	0.633
DOC_USP7_MATH_1	690	694	PF00917	0.765
DOC_USP7_MATH_1	695	699	PF00917	0.635
DOC_USP7_MATH_1	90	94	PF00917	0.513
DOC_USP7_MATH_2	78	84	PF00917	0.584
DOC_USP7_UBL2_3	530	534	PF12436	0.462
DOC_WW_Pin1_4	342	347	PF00397	0.465
DOC_WW_Pin1_4	682	687	PF00397	0.671
DOC_WW_Pin1_4	71	76	PF00397	0.472
DOC_WW_Pin1_4	715	720	PF00397	0.599
DOC_WW_Pin1_4	84	89	PF00397	0.600
LIG_14-3-3_CanoR_1	114	123	PF00244	0.449
LIG_14-3-3_CanoR_1	147	152	PF00244	0.486
LIG_14-3-3_CanoR_1	28	34	PF00244	0.454
LIG_14-3-3_CanoR_1	377	386	PF00244	0.432
LIG_14-3-3_CanoR_1	482	490	PF00244	0.496
LIG_14-3-3_CanoR_1	513	523	PF00244	0.495
LIG_14-3-3_CanoR_1	598	607	PF00244	0.570
LIG_14-3-3_CanoR_1	638	646	PF00244	0.483
LIG_14-3-3_CanoR_1	656	661	PF00244	0.657
LIG_14-3-3_CanoR_1	670	679	PF00244	0.648
LIG_14-3-3_CanoR_1	680	686	PF00244	0.597
LIG_14-3-3_CanoR_1	7	12	PF00244	0.471
LIG_Actin_WH2_2	360	375	PF00022	0.409
LIG_Actin_WH2_2	92	109	PF00022	0.450
LIG_AP2alpha_2	552	554	PF02296	0.456
LIG_BIR_II_1	1	5	PF00653	0.642
LIG_BRCT_BRCA1_1	292	296	PF00533	0.675
LIG_FHA_1	278	284	PF00498	0.702
LIG_FHA_1	392	398	PF00498	0.472
LIG_FHA_1	40	46	PF00498	0.578
LIG_FHA_1	47	53	PF00498	0.609
LIG_FHA_1	560	566	PF00498	0.508
LIG_FHA_1	683	689	PF00498	0.656
LIG_FHA_1	754	760	PF00498	0.612
LIG_FHA_2	276	282	PF00498	0.659
LIG_FHA_2	343	349	PF00498	0.440
LIG_FHA_2	378	384	PF00498	0.472
LIG_FHA_2	474	480	PF00498	0.557
LIG_FHA_2	637	643	PF00498	0.502
LIG_LIR_Apic_2	334	340	PF02991	0.482
LIG_LIR_Apic_2	358	363	PF02991	0.455
LIG_LIR_Gen_1	293	303	PF02991	0.471
LIG_LIR_Gen_1	348	356	PF02991	0.395
LIG_LIR_Gen_1	392	400	PF02991	0.426
LIG_LIR_Gen_1	426	437	PF02991	0.438
LIG_LIR_Gen_1	552	561	PF02991	0.609
LIG_LIR_Gen_1	582	589	PF02991	0.490
LIG_LIR_Nem_3	293	299	PF02991	0.493
LIG_LIR_Nem_3	348	353	PF02991	0.403
LIG_LIR_Nem_3	392	396	PF02991	0.474
LIG_LIR_Nem_3	426	432	PF02991	0.418
LIG_LIR_Nem_3	552	557	PF02991	0.468
LIG_LIR_Nem_3	582	588	PF02991	0.611
LIG_MYND_1	686	690	PF01753	0.668
LIG_Pex14_1	409	413	PF04695	0.500
LIG_Pex14_2	217	221	PF04695	0.450
LIG_Pex14_2	337	341	PF04695	0.530
LIG_Pex14_2	554	558	PF04695	0.579
LIG_SH2_NCK_1	429	433	PF00017	0.462
LIG_SH2_SRC	360	363	PF00017	0.464
LIG_SH2_STAP1	413	417	PF00017	0.482
LIG_SH2_STAT5	122	125	PF00017	0.515
LIG_SH2_STAT5	267	270	PF00017	0.585
LIG_SH2_STAT5	350	353	PF00017	0.452
LIG_SH2_STAT5	370	373	PF00017	0.293
LIG_SH2_STAT5	585	588	PF00017	0.500
LIG_SH3_1	72	78	PF00018	0.462
LIG_SH3_3	193	199	PF00018	0.638
LIG_SH3_3	547	553	PF00018	0.548
LIG_SH3_3	661	667	PF00018	0.640
LIG_SH3_3	683	689	PF00018	0.643
LIG_SH3_3	72	78	PF00018	0.473
LIG_Sin3_3	205	212	PF02671	0.534
LIG_SUMO_SIM_anti_2	246	252	PF11976	0.384
LIG_SUMO_SIM_anti_2	756	761	PF11976	0.631
LIG_SUMO_SIM_par_1	755	761	PF11976	0.615
LIG_TYR_ITIM	427	432	PF00017	0.372
LIG_TYR_ITIM	583	588	PF00017	0.618
LIG_WRC_WIRS_1	390	395	PF05994	0.427
MOD_CDK_SPK_2	342	347	PF00069	0.501
MOD_CK1_1	141	147	PF00069	0.489
MOD_CK1_1	2	8	PF00069	0.615
MOD_CK1_1	279	285	PF00069	0.554
MOD_CK1_1	323	329	PF00069	0.485
MOD_CK1_1	41	47	PF00069	0.448
MOD_CK1_1	616	622	PF00069	0.627
MOD_CK1_1	641	647	PF00069	0.557
MOD_CK1_1	659	665	PF00069	0.589
MOD_CK1_1	698	704	PF00069	0.677
MOD_CK1_1	715	721	PF00069	0.642
MOD_CK1_1	84	90	PF00069	0.542
MOD_CK2_1	21	27	PF00069	0.572
MOD_CK2_1	275	281	PF00069	0.662
MOD_CK2_1	294	300	PF00069	0.593
MOD_CK2_1	328	334	PF00069	0.578
MOD_CK2_1	408	414	PF00069	0.495
MOD_CK2_1	468	474	PF00069	0.649
MOD_CK2_1	71	77	PF00069	0.605
MOD_CK2_1	715	721	PF00069	0.629
MOD_Cter_Amidation	283	286	PF01082	0.489
MOD_GlcNHglycan	1	4	PF01048	0.642
MOD_GlcNHglycan	237	240	PF01048	0.518
MOD_GlcNHglycan	292	295	PF01048	0.744
MOD_GlcNHglycan	322	325	PF01048	0.611
MOD_GlcNHglycan	330	333	PF01048	0.557
MOD_GlcNHglycan	357	360	PF01048	0.465
MOD_GlcNHglycan	401	404	PF01048	0.520
MOD_GlcNHglycan	448	451	PF01048	0.402
MOD_GlcNHglycan	470	473	PF01048	0.758
MOD_GlcNHglycan	591	594	PF01048	0.594
MOD_GlcNHglycan	600	603	PF01048	0.593
MOD_GlcNHglycan	619	622	PF01048	0.676
MOD_GlcNHglycan	658	661	PF01048	0.659
MOD_GlcNHglycan	697	700	PF01048	0.741
MOD_GlcNHglycan	709	712	PF01048	0.645
MOD_GlcNHglycan	729	732	PF01048	0.521
MOD_GlcNHglycan	83	86	PF01048	0.616
MOD_GSK3_1	141	148	PF00069	0.489
MOD_GSK3_1	2	9	PF00069	0.615
MOD_GSK3_1	271	278	PF00069	0.662
MOD_GSK3_1	290	297	PF00069	0.648
MOD_GSK3_1	311	318	PF00069	0.611
MOD_GSK3_1	319	326	PF00069	0.601
MOD_GSK3_1	37	44	PF00069	0.523
MOD_GSK3_1	373	380	PF00069	0.476
MOD_GSK3_1	446	453	PF00069	0.411
MOD_GSK3_1	572	579	PF00069	0.598
MOD_GSK3_1	612	619	PF00069	0.656
MOD_GSK3_1	634	641	PF00069	0.543
MOD_GSK3_1	647	654	PF00069	0.804
MOD_GSK3_1	668	675	PF00069	0.630
MOD_GSK3_1	695	702	PF00069	0.540
MOD_GSK3_1	707	714	PF00069	0.541
MOD_GSK3_1	723	730	PF00069	0.526
MOD_GSK3_1	731	738	PF00069	0.698
MOD_GSK3_1	80	87	PF00069	0.636
MOD_LATS_1	145	151	PF00433	0.457
MOD_LATS_1	492	498	PF00433	0.469
MOD_N-GLC_1	315	320	PF02516	0.642
MOD_N-GLC_1	52	57	PF02516	0.601
MOD_N-GLC_1	80	85	PF02516	0.605
MOD_NEK2_1	207	212	PF00069	0.613
MOD_NEK2_1	298	303	PF00069	0.684
MOD_NEK2_1	372	377	PF00069	0.412
MOD_NEK2_1	389	394	PF00069	0.448
MOD_NEK2_1	399	404	PF00069	0.544
MOD_NEK2_1	437	442	PF00069	0.414
MOD_NEK2_1	581	586	PF00069	0.504
MOD_NEK2_1	589	594	PF00069	0.627
MOD_NEK2_1	614	619	PF00069	0.606
MOD_NEK2_1	724	729	PF00069	0.661
MOD_NEK2_1	735	740	PF00069	0.549
MOD_NEK2_2	525	530	PF00069	0.451
MOD_PIKK_1	115	121	PF00454	0.450
MOD_PIKK_1	362	368	PF00454	0.451
MOD_PIKK_1	391	397	PF00454	0.523
MOD_PIKK_1	437	443	PF00454	0.364
MOD_PIKK_1	481	487	PF00454	0.463
MOD_PIKK_1	614	620	PF00454	0.766
MOD_PK_1	14	20	PF00069	0.512
MOD_PK_1	224	230	PF00069	0.492
MOD_PKA_1	656	662	PF00069	0.661
MOD_PKA_1	681	687	PF00069	0.656
MOD_PKA_1	706	712	PF00069	0.660
MOD_PKA_2	138	144	PF00069	0.492
MOD_PKA_2	372	378	PF00069	0.479
MOD_PKA_2	446	452	PF00069	0.405
MOD_PKA_2	481	487	PF00069	0.515
MOD_PKA_2	6	12	PF00069	0.473
MOD_PKA_2	656	662	PF00069	0.661
MOD_PKA_2	671	677	PF00069	0.622
MOD_PKA_2	681	687	PF00069	0.602
MOD_PKA_2	699	705	PF00069	0.583
MOD_PKA_2	706	712	PF00069	0.807
MOD_PKA_2	746	752	PF00069	0.535
MOD_PKB_1	113	121	PF00069	0.448
MOD_PKB_1	233	241	PF00069	0.376
MOD_PKB_1	668	676	PF00069	0.684
MOD_Plk_1	473	479	PF00069	0.569
MOD_Plk_1	579	585	PF00069	0.501
MOD_Plk_2-3	21	27	PF00069	0.506
MOD_Plk_2-3	474	480	PF00069	0.557
MOD_Plk_2-3	559	565	PF00069	0.514
MOD_Plk_4	14	20	PF00069	0.592
MOD_Plk_4	224	230	PF00069	0.454
MOD_Plk_4	29	35	PF00069	0.561
MOD_Plk_4	581	587	PF00069	0.478
MOD_Plk_4	61	67	PF00069	0.525
MOD_Plk_4	90	96	PF00069	0.386
MOD_ProDKin_1	342	348	PF00069	0.452
MOD_ProDKin_1	682	688	PF00069	0.670
MOD_ProDKin_1	71	77	PF00069	0.476
MOD_ProDKin_1	715	721	PF00069	0.602
MOD_ProDKin_1	84	90	PF00069	0.594
TRG_DiLeu_BaLyEn_6	584	589	PF01217	0.456
TRG_ENDOCYTIC_2	350	353	PF00928	0.403
TRG_ENDOCYTIC_2	390	393	PF00928	0.387
TRG_ENDOCYTIC_2	429	432	PF00928	0.398
TRG_ENDOCYTIC_2	551	554	PF00928	0.471
TRG_ENDOCYTIC_2	585	588	PF00928	0.648
TRG_ER_diArg_1	113	115	PF00400	0.511
TRG_ER_diArg_1	129	131	PF00400	0.493
TRG_ER_diArg_1	162	164	PF00400	0.467
TRG_ER_diArg_1	177	180	PF00400	0.511
TRG_ER_diArg_1	215	217	PF00400	0.485
TRG_ER_diArg_1	232	234	PF00400	0.454
TRG_ER_diArg_1	667	670	PF00400	0.742
TRG_ER_diArg_1	679	682	PF00400	0.658
TRG_NES_CRM1_1	485	499	PF08389	0.497
TRG_NLS_Bipartite_1	215	235	PF00514	0.450
TRG_NLS_MonoExtC_3	230	235	PF00514	0.370
TRG_Pf-PMV_PEXEL_1	114	119	PF00026	0.466
TRG_Pf-PMV_PEXEL_1	147	152	PF00026	0.581
TRG_Pf-PMV_PEXEL_1	153	157	PF00026	0.509
TRG_Pf-PMV_PEXEL_1	163	167	PF00026	0.402
TRG_Pf-PMV_PEXEL_1	410	414	PF00026	0.467

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0P210	Trypanosomatidae	29%	100%
A0A3Q8IBV7	Leishmania donovani	86%	100%
A4HI38	Leishmania braziliensis	70%	100%
A4I5B5	Leishmania infantum	85%	100%
C6K3X2	Leptomonas seymouri	44%	97%
Q4Q7M1	Leishmania major	85%	99%