Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0K9_LEIMU

TriTrypDb:

LmxM.29.0808

Length:

248

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

E9B0K9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0K9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	154	158	PF00656	0.685
CLV_C14_Caspase3-7	177	181	PF00656	0.695
CLV_NRD_NRD_1	135	137	PF00675	0.548
CLV_PCSK_KEX2_1	135	137	PF00082	0.548
DEG_Nend_UBRbox_3	1	3	PF02207	0.499
DOC_CYCLIN_yCln2_LP_2	160	166	PF00134	0.674
DOC_PP2B_LxvP_1	221	224	PF13499	0.806
DOC_PP2B_LxvP_1	231	234	PF13499	0.728
DOC_USP7_MATH_1	169	173	PF00917	0.668
DOC_USP7_MATH_1	212	216	PF00917	0.692
DOC_USP7_MATH_1	40	44	PF00917	0.682
DOC_USP7_MATH_1	71	75	PF00917	0.493
DOC_USP7_MATH_1	9	13	PF00917	0.452
DOC_WW_Pin1_4	181	186	PF00397	0.800
LIG_14-3-3_CanoR_1	136	146	PF00244	0.804
LIG_APCC_ABBA_1	99	104	PF00400	0.491
LIG_BRCT_BRCA1_1	56	60	PF00533	0.452
LIG_CtBP_PxDLS_1	233	237	PF00389	0.624
LIG_FHA_1	166	172	PF00498	0.694
LIG_FHA_1	223	229	PF00498	0.826
LIG_FHA_1	242	248	PF00498	0.600
LIG_FHA_2	138	144	PF00498	0.752
LIG_LIR_Apic_2	214	220	PF02991	0.763
LIG_LIR_Gen_1	174	183	PF02991	0.696
LIG_LIR_Nem_3	13	19	PF02991	0.452
LIG_LIR_Nem_3	174	179	PF02991	0.722
LIG_LIR_Nem_3	187	192	PF02991	0.701
LIG_LIR_Nem_3	48	54	PF02991	0.505
LIG_NRBOX	24	30	PF00104	0.355
LIG_PDZ_Class_2	243	248	PF00595	0.767
LIG_Pex14_1	96	100	PF04695	0.452
LIG_Pex14_2	47	51	PF04695	0.510
LIG_PTB_Apo_2	103	110	PF02174	0.551
LIG_SH2_CRK	16	20	PF00017	0.452
LIG_SH2_CRK	217	221	PF00017	0.769
LIG_SH2_NCK_1	139	143	PF00017	0.757
LIG_SH2_STAP1	72	76	PF00017	0.337
LIG_SH2_STAT5	100	103	PF00017	0.637
LIG_SH2_STAT5	137	140	PF00017	0.754
LIG_SUMO_SIM_par_1	219	225	PF11976	0.805
LIG_TYR_ITIM	14	19	PF00017	0.238
LIG_UBA3_1	25	34	PF00899	0.614
MOD_CK1_1	241	247	PF00069	0.767
MOD_CK2_1	171	177	PF00069	0.697
MOD_GlcNHglycan	131	134	PF01048	0.483
MOD_GlcNHglycan	157	160	PF01048	0.488
MOD_GlcNHglycan	171	174	PF01048	0.464
MOD_GSK3_1	151	158	PF00069	0.718
MOD_GSK3_1	165	172	PF00069	0.662
MOD_GSK3_1	50	57	PF00069	0.504
MOD_N-GLC_1	192	197	PF02516	0.422
MOD_NEK2_1	28	33	PF00069	0.410
MOD_NEK2_1	50	55	PF00069	0.513
MOD_NEK2_2	45	50	PF00069	0.376
MOD_PIKK_1	184	190	PF00454	0.770
MOD_PK_1	151	157	PF00069	0.691
MOD_Plk_1	238	244	PF00069	0.774
MOD_Plk_4	113	119	PF00069	0.648
MOD_Plk_4	212	218	PF00069	0.768
MOD_Plk_4	232	238	PF00069	0.626
MOD_Plk_4	54	60	PF00069	0.495
MOD_ProDKin_1	181	187	PF00069	0.799
MOD_SUMO_rev_2	143	153	PF00179	0.604
TRG_DiLeu_BaEn_1	232	237	PF01217	0.626
TRG_DiLeu_BaEn_1	75	80	PF01217	0.380
TRG_ENDOCYTIC_2	16	19	PF00928	0.452
TRG_ER_diArg_1	135	137	PF00400	0.748

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X345	Leishmania donovani	86%	100%
A4I5B3	Leishmania infantum	86%	100%
Q4Q7M3	Leishmania major	86%	100%