Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0K6_LEIMU

TriTrypDb:

LmxM.29.0790

Length:

396

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0K6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0K6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	117	121	PF00656	0.572
CLV_C14_Caspase3-7	128	132	PF00656	0.502
CLV_C14_Caspase3-7	151	155	PF00656	0.608
CLV_NRD_NRD_1	194	196	PF00675	0.639
CLV_NRD_NRD_1	214	216	PF00675	0.562
CLV_NRD_NRD_1	332	334	PF00675	0.560
CLV_NRD_NRD_1	350	352	PF00675	0.532
CLV_NRD_NRD_1	358	360	PF00675	0.475
CLV_PCSK_KEX2_1	349	351	PF00082	0.525
CLV_PCSK_KEX2_1	358	360	PF00082	0.464
CLV_PCSK_KEX2_1	42	44	PF00082	0.579
CLV_PCSK_KEX2_1	80	82	PF00082	0.533
CLV_PCSK_PC1ET2_1	42	44	PF00082	0.579
CLV_PCSK_PC1ET2_1	80	82	PF00082	0.505
CLV_PCSK_SKI1_1	162	166	PF00082	0.586
CLV_PCSK_SKI1_1	315	319	PF00082	0.457
CLV_PCSK_SKI1_1	333	337	PF00082	0.573
CLV_PCSK_SKI1_1	371	375	PF00082	0.631
CLV_PCSK_SKI1_1	42	46	PF00082	0.615
CLV_Separin_Metazoa	159	163	PF03568	0.581
DEG_APCC_DBOX_1	350	358	PF00400	0.519
DEG_SCF_FBW7_2	150	156	PF00400	0.611
DOC_CKS1_1	150	155	PF01111	0.612
DOC_MAPK_gen_1	349	357	PF00069	0.523
DOC_MAPK_gen_1	358	365	PF00069	0.384
DOC_MAPK_MEF2A_6	23	31	PF00069	0.477
DOC_MAPK_RevD_3	29	43	PF00069	0.542
DOC_PP2B_LxvP_1	138	141	PF13499	0.570
DOC_USP7_MATH_1	122	126	PF00917	0.446
DOC_USP7_MATH_1	141	145	PF00917	0.619
DOC_USP7_MATH_1	282	286	PF00917	0.651
DOC_WW_Pin1_4	149	154	PF00397	0.621
DOC_WW_Pin1_4	202	207	PF00397	0.685
DOC_WW_Pin1_4	287	292	PF00397	0.518
DOC_WW_Pin1_4	316	321	PF00397	0.622
LIG_14-3-3_CanoR_1	135	141	PF00244	0.595
LIG_14-3-3_CanoR_1	224	234	PF00244	0.524
LIG_14-3-3_CanoR_1	245	254	PF00244	0.598
LIG_14-3-3_CanoR_1	333	338	PF00244	0.621
LIG_14-3-3_CanoR_1	43	47	PF00244	0.714
LIG_APCC_ABBA_1	61	66	PF00400	0.616
LIG_BIR_II_1	1	5	PF00653	0.550
LIG_BRCT_BRCA1_1	222	226	PF00533	0.672
LIG_FHA_1	155	161	PF00498	0.544
LIG_FHA_1	236	242	PF00498	0.646
LIG_FHA_1	279	285	PF00498	0.737
LIG_FHA_1	30	36	PF00498	0.564
LIG_FHA_1	330	336	PF00498	0.560
LIG_FHA_2	341	347	PF00498	0.551
LIG_FHA_2	46	52	PF00498	0.637
LIG_LIR_Gen_1	125	134	PF02991	0.589
LIG_LIR_Nem_3	125	130	PF02991	0.581
LIG_LIR_Nem_3	2	7	PF02991	0.608
LIG_LIR_Nem_3	379	383	PF02991	0.454
LIG_Pex14_3	160	165	PF04695	0.578
LIG_RPA_C_Fungi	354	366	PF08784	0.439
LIG_SH2_STAT5	360	363	PF00017	0.493
LIG_SH2_STAT5	383	386	PF00017	0.355
LIG_SH3_3	147	153	PF00018	0.632
LIG_SH3_3	228	234	PF00018	0.652
LIG_SH3_3	314	320	PF00018	0.532
LIG_SUMO_SIM_anti_2	156	163	PF11976	0.581
LIG_SUMO_SIM_anti_2	352	358	PF11976	0.514
LIG_TRAF2_1	102	105	PF00917	0.482
LIG_TRAF2_1	48	51	PF00917	0.629
LIG_WRC_WIRS_1	4	9	PF05994	0.561
MOD_CK1_1	139	145	PF00069	0.581
MOD_CK1_1	14	20	PF00069	0.492
MOD_CK1_1	205	211	PF00069	0.661
MOD_CK1_1	225	231	PF00069	0.504
MOD_CK1_1	235	241	PF00069	0.645
MOD_CK1_1	285	291	PF00069	0.619
MOD_CK2_1	122	128	PF00069	0.577
MOD_CK2_1	254	260	PF00069	0.716
MOD_CK2_1	286	292	PF00069	0.593
MOD_CK2_1	3	9	PF00069	0.559
MOD_CK2_1	340	346	PF00069	0.554
MOD_CK2_1	45	51	PF00069	0.627
MOD_Cter_Amidation	57	60	PF01082	0.639
MOD_GlcNHglycan	1	4	PF01048	0.548
MOD_GlcNHglycan	13	16	PF01048	0.568
MOD_GlcNHglycan	141	144	PF01048	0.565
MOD_GlcNHglycan	19	22	PF01048	0.575
MOD_GlcNHglycan	207	210	PF01048	0.552
MOD_GlcNHglycan	304	307	PF01048	0.491
MOD_GlcNHglycan	320	323	PF01048	0.552
MOD_GSK3_1	218	225	PF00069	0.613
MOD_GSK3_1	259	266	PF00069	0.668
MOD_GSK3_1	278	285	PF00069	0.611
MOD_GSK3_1	298	305	PF00069	0.572
MOD_GSK3_1	329	336	PF00069	0.499
MOD_GSK3_1	388	395	PF00069	0.521
MOD_GSK3_1	88	95	PF00069	0.611
MOD_LATS_1	331	337	PF00433	0.510
MOD_N-GLC_1	202	207	PF02516	0.522
MOD_N-GLC_1	388	393	PF02516	0.510
MOD_NEK2_1	226	231	PF00069	0.727
MOD_NEK2_1	261	266	PF00069	0.643
MOD_NEK2_1	29	34	PF00069	0.602
MOD_NEK2_1	337	342	PF00069	0.557
MOD_NEK2_1	88	93	PF00069	0.609
MOD_NEK2_2	3	8	PF00069	0.557
MOD_PIKK_1	29	35	PF00454	0.601
MOD_PIKK_1	88	94	PF00454	0.641
MOD_PK_1	247	253	PF00069	0.497
MOD_PKA_1	333	339	PF00069	0.506
MOD_PKA_1	42	48	PF00069	0.625
MOD_PKA_2	174	180	PF00069	0.631
MOD_PKA_2	190	196	PF00069	0.582
MOD_PKA_2	226	232	PF00069	0.720
MOD_PKA_2	246	252	PF00069	0.599
MOD_PKA_2	298	304	PF00069	0.492
MOD_PKA_2	42	48	PF00069	0.625
MOD_PKB_1	243	251	PF00069	0.624
MOD_Plk_1	388	394	PF00069	0.518
MOD_Plk_2-3	154	160	PF00069	0.585
MOD_ProDKin_1	149	155	PF00069	0.618
MOD_ProDKin_1	202	208	PF00069	0.686
MOD_ProDKin_1	287	293	PF00069	0.518
MOD_ProDKin_1	316	322	PF00069	0.618
TRG_DiLeu_BaEn_1	156	161	PF01217	0.580
TRG_DiLeu_BaEn_1	352	357	PF01217	0.511
TRG_DiLeu_BaEn_4	352	358	PF01217	0.514
TRG_ENDOCYTIC_2	360	363	PF00928	0.441
TRG_ER_diArg_1	242	245	PF00400	0.616
TRG_ER_diArg_1	348	351	PF00400	0.528
TRG_ER_diArg_1	357	359	PF00400	0.470
TRG_NES_CRM1_1	25	40	PF08389	0.605
TRG_Pf-PMV_PEXEL_1	371	375	PF00026	0.529
TRG_Pf-PMV_PEXEL_1	386	390	PF00026	0.375

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X346	Leishmania donovani	86%	93%
A4I5B0	Leishmania infantum	86%	93%
C6K3W7	Leptomonas seymouri	28%	94%
Q4Q7M6	Leishmania major	84%	100%