LeishMANIAdb
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Fido domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Fido domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9B0K4_LEIMU
TriTrypDb:
LmxM.29.0770
Length:
124

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005654 nucleoplasm 2 1
GO:0005815 microtubule organizing center 2 1
GO:0005930 axoneme 2 1
GO:0036064 ciliary basal body 3 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9B0K4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0K4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 85 89 PF00656 0.350
CLV_PCSK_KEX2_1 110 112 PF00082 0.424
CLV_PCSK_KEX2_1 70 72 PF00082 0.556
CLV_PCSK_PC1ET2_1 110 112 PF00082 0.424
CLV_PCSK_PC1ET2_1 70 72 PF00082 0.588
CLV_PCSK_SKI1_1 34 38 PF00082 0.547
DEG_MDM2_SWIB_1 86 94 PF02201 0.390
DEG_Nend_UBRbox_3 1 3 PF02207 0.655
DOC_PP1_RVXF_1 32 39 PF00149 0.480
DOC_PP4_FxxP_1 38 41 PF00568 0.507
LIG_14-3-3_CanoR_1 98 106 PF00244 0.313
LIG_FHA_2 5 11 PF00498 0.456
LIG_LIR_Gen_1 27 37 PF02991 0.379
LIG_LIR_Nem_3 27 32 PF02991 0.384
LIG_PCNA_PIPBox_1 22 31 PF02747 0.573
LIG_PCNA_yPIPBox_3 17 29 PF02747 0.587
LIG_Pex14_2 86 90 PF04695 0.385
LIG_SH2_SRC 112 115 PF00017 0.494
LIG_SH2_STAT3 19 22 PF00017 0.472
LIG_SH2_STAT5 112 115 PF00017 0.421
LIG_SH2_STAT5 19 22 PF00017 0.437
LIG_SH2_STAT5 47 50 PF00017 0.237
LIG_SH2_STAT5 77 80 PF00017 0.323
LIG_WRC_WIRS_1 83 88 PF05994 0.344
MOD_CK2_1 4 10 PF00069 0.418
MOD_GlcNHglycan 62 65 PF01048 0.620
MOD_GSK3_1 115 122 PF00069 0.586
MOD_GSK3_1 56 63 PF00069 0.550
MOD_N-GLC_1 56 61 PF02516 0.582
MOD_NEK2_1 81 86 PF00069 0.251
MOD_PKA_2 20 26 PF00069 0.425
MOD_PKA_2 97 103 PF00069 0.351
MOD_PKB_1 96 104 PF00069 0.532
MOD_Plk_1 9 15 PF00069 0.346
MOD_Plk_2-3 9 15 PF00069 0.399
MOD_Plk_4 47 53 PF00069 0.339
MOD_Plk_4 82 88 PF00069 0.488
TRG_ENDOCYTIC_2 29 32 PF00928 0.534
TRG_Pf-PMV_PEXEL_1 76 80 PF00026 0.391

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0S4JBX9 Bodo saltans 50% 100%
A0A1X0P2S3 Trypanosomatidae 53% 100%
A0A3R7MCC7 Trypanosoma rangeli 50% 81%
A0A3S7X371 Leishmania donovani 81% 100%
A4HI32 Leishmania braziliensis 58% 100%
A4I5A8 Leishmania infantum 81% 100%
C6K3W5 Leptomonas seymouri 60% 100%
C9ZQP2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 96%
Q4Q7M8 Leishmania major 75% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS