Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0K1_LEIMU

TriTrypDb:

LmxM.29.0745

Length:

279

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0K1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0K1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	102	106	PF00656	0.488
CLV_NRD_NRD_1	4	6	PF00675	0.601
CLV_NRD_NRD_1	94	96	PF00675	0.548
CLV_PCSK_FUR_1	92	96	PF00082	0.494
CLV_PCSK_KEX2_1	4	6	PF00082	0.623
CLV_PCSK_KEX2_1	55	57	PF00082	0.754
CLV_PCSK_KEX2_1	91	93	PF00082	0.652
CLV_PCSK_KEX2_1	94	96	PF00082	0.636
CLV_PCSK_PC1ET2_1	55	57	PF00082	0.598
CLV_PCSK_PC1ET2_1	91	93	PF00082	0.652
CLV_PCSK_SKI1_1	130	134	PF00082	0.592
CLV_PCSK_SKI1_1	98	102	PF00082	0.552
DEG_COP1_1	69	78	PF00400	0.513
DEG_Nend_Nbox_1	1	3	PF02207	0.678
DEG_SCF_FBW7_1	68	74	PF00400	0.558
DOC_CDC14_PxL_1	157	165	PF14671	0.502
DOC_CKS1_1	68	73	PF01111	0.480
DOC_PP1_RVXF_1	12	19	PF00149	0.671
DOC_USP7_MATH_1	116	120	PF00917	0.549
DOC_USP7_MATH_1	231	235	PF00917	0.545
DOC_USP7_MATH_1	62	66	PF00917	0.782
DOC_USP7_MATH_1	76	80	PF00917	0.673
DOC_WW_Pin1_4	140	145	PF00397	0.641
DOC_WW_Pin1_4	64	69	PF00397	0.590
LIG_14-3-3_CanoR_1	127	133	PF00244	0.427
LIG_14-3-3_CanoR_1	7	16	PF00244	0.607
LIG_FHA_1	113	119	PF00498	0.692
LIG_FHA_1	194	200	PF00498	0.413
LIG_FHA_1	99	105	PF00498	0.484
LIG_LIR_Gen_1	146	155	PF02991	0.531
LIG_LIR_Gen_1	214	225	PF02991	0.381
LIG_LIR_Nem_3	146	150	PF02991	0.534
LIG_LIR_Nem_3	214	220	PF02991	0.327
LIG_NRBOX	103	109	PF00104	0.548
LIG_SH2_CRK	205	209	PF00017	0.372
LIG_SH2_NCK_1	205	209	PF00017	0.357
LIG_SH2_PTP2	263	266	PF00017	0.471
LIG_SH2_SRC	123	126	PF00017	0.610
LIG_SH2_STAT5	123	126	PF00017	0.521
LIG_SH2_STAT5	263	266	PF00017	0.471
LIG_SH3_3	175	181	PF00018	0.433
LIG_SH3_3	184	190	PF00018	0.485
LIG_SH3_3	65	71	PF00018	0.691
LIG_TRAF2_1	100	103	PF00917	0.574
LIG_TRAF2_1	143	146	PF00917	0.651
MOD_CK1_1	111	117	PF00069	0.554
MOD_CK1_1	166	172	PF00069	0.488
MOD_CK1_1	64	70	PF00069	0.690
MOD_CK2_1	131	137	PF00069	0.461
MOD_CK2_1	140	146	PF00069	0.470
MOD_CK2_1	150	156	PF00069	0.462
MOD_CMANNOS	15	18	PF00535	0.600
MOD_GlcNHglycan	119	122	PF01048	0.663
MOD_GlcNHglycan	134	137	PF01048	0.432
MOD_GlcNHglycan	165	168	PF01048	0.581
MOD_GlcNHglycan	227	230	PF01048	0.390
MOD_GlcNHglycan	63	67	PF01048	0.723
MOD_GlcNHglycan	76	79	PF01048	0.644
MOD_GSK3_1	108	115	PF00069	0.606
MOD_GSK3_1	128	135	PF00069	0.600
MOD_GSK3_1	166	173	PF00069	0.497
MOD_GSK3_1	176	183	PF00069	0.346
MOD_GSK3_1	219	226	PF00069	0.432
MOD_GSK3_1	248	255	PF00069	0.336
MOD_GSK3_1	62	69	PF00069	0.693
MOD_GSK3_1	74	81	PF00069	0.624
MOD_N-GLC_1	108	113	PF02516	0.513
MOD_N-GLC_1	269	274	PF02516	0.328
MOD_NEK2_1	108	113	PF00069	0.513
MOD_NEK2_1	150	155	PF00069	0.640
MOD_NEK2_1	163	168	PF00069	0.502
MOD_NEK2_1	212	217	PF00069	0.497
MOD_NEK2_1	61	66	PF00069	0.709
MOD_NEK2_2	47	52	PF00069	0.659
MOD_PK_1	22	28	PF00069	0.750
MOD_PKA_1	55	61	PF00069	0.609
MOD_PKA_2	112	118	PF00069	0.549
MOD_PKA_2	163	169	PF00069	0.606
MOD_PKA_2	55	61	PF00069	0.522
MOD_PKB_1	5	13	PF00069	0.481
MOD_Plk_1	269	275	PF00069	0.335
MOD_Plk_1	47	53	PF00069	0.670
MOD_Plk_4	128	134	PF00069	0.651
MOD_Plk_4	170	176	PF00069	0.435
MOD_Plk_4	212	218	PF00069	0.294
MOD_Plk_4	22	28	PF00069	0.637
MOD_Plk_4	269	275	PF00069	0.423
MOD_ProDKin_1	140	146	PF00069	0.644
MOD_ProDKin_1	64	70	PF00069	0.588
MOD_SUMO_rev_2	77	83	PF00179	0.515
TRG_DiLeu_BaEn_1	103	108	PF01217	0.571
TRG_ER_diArg_1	12	15	PF00400	0.621
TRG_ER_diArg_1	3	5	PF00400	0.662
TRG_ER_diArg_1	92	95	PF00400	0.618
TRG_NLS_MonoExtC_3	90	95	PF00514	0.497
TRG_NLS_MonoExtN_4	89	95	PF00514	0.496
TRG_Pf-PMV_PEXEL_1	95	99	PF00026	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFH4	Leptomonas seymouri	50%	100%
A0A0S4JGE4	Bodo saltans	30%	81%
A0A1X0P245	Trypanosomatidae	33%	89%
A0A3S7X369	Leishmania donovani	93%	100%
A0A422P4T3	Trypanosoma rangeli	35%	99%
A4HI29	Leishmania braziliensis	83%	100%
A4I5A5	Leishmania infantum	92%	100%
C9ZQN9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	97%
Q4Q7N1	Leishmania major	92%	100%
V5BUA0	Trypanosoma cruzi	36%	99%