Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0F4_LEIMU

TriTrypDb:

LmxM.29.0300

Length:

148

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0F4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0F4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	62	64	PF00675	0.600
CLV_PCSK_KEX2_1	62	64	PF00082	0.572
CLV_PCSK_SKI1_1	25	29	PF00082	0.546
DOC_ANK_TNKS_1	115	122	PF00023	0.457
DOC_PP2B_LxvP_1	36	39	PF13499	0.633
DOC_USP7_MATH_1	127	131	PF00917	0.536
DOC_USP7_MATH_1	71	75	PF00917	0.535
DOC_WW_Pin1_4	104	109	PF00397	0.525
DOC_WW_Pin1_4	47	52	PF00397	0.693
LIG_14-3-3_CanoR_1	30	39	PF00244	0.599
LIG_14-3-3_CanoR_1	9	16	PF00244	0.531
LIG_14-3-3_CanoR_1	93	99	PF00244	0.521
LIG_BIR_II_1	1	5	PF00653	0.607
LIG_BRCT_BRCA1_1	129	133	PF00533	0.566
LIG_BRCT_BRCA1_1	79	83	PF00533	0.519
LIG_deltaCOP1_diTrp_1	124	133	PF00928	0.533
LIG_FHA_1	109	115	PF00498	0.588
LIG_FHA_1	74	80	PF00498	0.740
LIG_FHA_2	105	111	PF00498	0.510
LIG_LIR_Apic_2	11	16	PF02991	0.607
LIG_LIR_Gen_1	106	117	PF02991	0.581
LIG_LIR_Nem_3	106	112	PF02991	0.541
LIG_LIR_Nem_3	21	27	PF02991	0.522
LIG_LIR_Nem_3	80	86	PF02991	0.524
LIG_NRBOX	2	8	PF00104	0.601
LIG_PTB_Apo_2	78	85	PF02174	0.532
LIG_SH2_CRK	109	113	PF00017	0.531
LIG_SH2_CRK	24	28	PF00017	0.525
LIG_SH2_NCK_1	109	113	PF00017	0.580
LIG_SH2_PTP2	13	16	PF00017	0.558
LIG_SH2_STAT3	65	68	PF00017	0.474
LIG_SH2_STAT5	13	16	PF00017	0.600
LIG_SUMO_SIM_par_1	110	115	PF11976	0.590
LIG_TYR_ITSM	105	112	PF00017	0.562
MOD_CK1_1	29	35	PF00069	0.609
MOD_CK1_1	43	49	PF00069	0.517
MOD_CK2_1	54	60	PF00069	0.688
MOD_CK2_1	71	77	PF00069	0.474
MOD_Cter_Amidation	60	63	PF01082	0.592
MOD_GlcNHglycan	18	21	PF01048	0.552
MOD_GlcNHglycan	3	6	PF01048	0.664
MOD_GlcNHglycan	40	43	PF01048	0.640
MOD_GSK3_1	104	111	PF00069	0.554
MOD_GSK3_1	14	21	PF00069	0.546
MOD_GSK3_1	26	33	PF00069	0.711
MOD_GSK3_1	38	45	PF00069	0.494
MOD_GSK3_1	50	57	PF00069	0.490
MOD_GSK3_1	73	80	PF00069	0.543
MOD_NEK2_1	1	6	PF00069	0.571
MOD_NEK2_1	18	23	PF00069	0.474
MOD_NEK2_1	44	49	PF00069	0.600
MOD_NEK2_2	54	59	PF00069	0.578
MOD_NEK2_2	8	13	PF00069	0.571
MOD_PKA_2	29	35	PF00069	0.557
MOD_PKA_2	8	14	PF00069	0.610
MOD_PKA_2	92	98	PF00069	0.516
MOD_Plk_2-3	110	116	PF00069	0.593
MOD_Plk_2-3	73	79	PF00069	0.538
MOD_ProDKin_1	104	110	PF00069	0.530
MOD_ProDKin_1	47	53	PF00069	0.693
TRG_DiLeu_BaEn_1	136	141	PF01217	0.492
TRG_DiLeu_BaEn_2	128	134	PF01217	0.521
TRG_ENDOCYTIC_2	109	112	PF00928	0.551
TRG_ENDOCYTIC_2	24	27	PF00928	0.588

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IM95	Leptomonas seymouri	53%	95%
A0A3S7X2Y5	Leishmania donovani	93%	100%
A4HHX4	Leishmania braziliensis	79%	100%
A4I524	Leishmania infantum	93%	100%
Q4Q7S9	Leishmania major	91%	100%