Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0C1_LEIMU

TriTrypDb:

LmxM.28.2990

Length:

235

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0C1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0C1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	133	135	PF00675	0.419
CLV_NRD_NRD_1	165	167	PF00675	0.468
CLV_NRD_NRD_1	17	19	PF00675	0.540
CLV_PCSK_KEX2_1	165	167	PF00082	0.421
CLV_PCSK_KEX2_1	17	19	PF00082	0.606
CLV_PCSK_SKI1_1	105	109	PF00082	0.508
CLV_PCSK_SKI1_1	194	198	PF00082	0.616
CLV_Separin_Metazoa	229	233	PF03568	0.448
DEG_APCC_DBOX_1	213	221	PF00400	0.402
DEG_APCC_DBOX_1	66	74	PF00400	0.484
DOC_ANK_TNKS_1	52	59	PF00023	0.513
DOC_USP7_MATH_1	222	226	PF00917	0.539
DOC_USP7_UBL2_3	135	139	PF12436	0.392
DOC_USP7_UBL2_3	147	151	PF12436	0.413
DOC_WW_Pin1_4	187	192	PF00397	0.577
DOC_WW_Pin1_4	196	201	PF00397	0.503
DOC_WW_Pin1_4	72	77	PF00397	0.464
LIG_14-3-3_CanoR_1	174	183	PF00244	0.405
LIG_14-3-3_CterR_2	232	235	PF00244	0.520
LIG_BRCT_BRCA1_1	158	162	PF00533	0.393
LIG_CaM_IQ_9	39	55	PF13499	0.461
LIG_FHA_1	175	181	PF00498	0.396
LIG_FHA_1	23	29	PF00498	0.593
LIG_FHA_1	52	58	PF00498	0.528
LIG_FHA_2	109	115	PF00498	0.446
LIG_FHA_2	39	45	PF00498	0.536
LIG_LIR_Gen_1	91	100	PF02991	0.450
LIG_LIR_Nem_3	130	136	PF02991	0.458
LIG_LIR_Nem_3	91	97	PF02991	0.468
LIG_MLH1_MIPbox_1	158	162	PF16413	0.393
LIG_NRBOX	226	232	PF00104	0.494
LIG_SH2_STAT5	161	164	PF00017	0.439
LIG_SH2_STAT5	64	67	PF00017	0.600
LIG_SH3_2	100	105	PF14604	0.446
LIG_SH3_3	177	183	PF00018	0.498
LIG_SH3_3	185	191	PF00018	0.589
LIG_SH3_3	97	103	PF00018	0.451
LIG_SUMO_SIM_anti_2	5	11	PF11976	0.423
LIG_SUMO_SIM_par_1	182	187	PF11976	0.609
LIG_TRAF2_1	111	114	PF00917	0.447
LIG_TRAF2_1	209	212	PF00917	0.528
LIG_TRAF2_1	41	44	PF00917	0.530
LIG_TRAF2_2	200	205	PF00917	0.584
MOD_CDK_SPxxK_3	187	194	PF00069	0.580
MOD_CK1_1	206	212	PF00069	0.520
MOD_CK2_1	108	114	PF00069	0.454
MOD_CK2_1	206	212	PF00069	0.553
MOD_CK2_1	222	228	PF00069	0.341
MOD_CK2_1	38	44	PF00069	0.535
MOD_CK2_1	68	74	PF00069	0.476
MOD_GlcNHglycan	20	23	PF01048	0.522
MOD_GlcNHglycan	208	211	PF01048	0.483
MOD_GlcNHglycan	34	37	PF01048	0.463
MOD_GSK3_1	18	25	PF00069	0.523
MOD_GSK3_1	28	35	PF00069	0.516
MOD_GSK3_1	68	75	PF00069	0.471
MOD_N-GLC_1	222	227	PF02516	0.448
MOD_NEK2_1	204	209	PF00069	0.488
MOD_NEK2_1	29	34	PF00069	0.490
MOD_NEK2_1	38	43	PF00069	0.510
MOD_PIKK_1	156	162	PF00454	0.412
MOD_PIKK_1	174	180	PF00454	0.426
MOD_PKA_2	173	179	PF00069	0.380
MOD_PKA_2	5	11	PF00069	0.600
MOD_PKB_1	172	180	PF00069	0.442
MOD_Plk_1	204	210	PF00069	0.579
MOD_Plk_1	222	228	PF00069	0.324
MOD_Plk_1	68	74	PF00069	0.476
MOD_Plk_4	24	30	PF00069	0.533
MOD_Plk_4	5	11	PF00069	0.543
MOD_ProDKin_1	187	193	PF00069	0.578
MOD_ProDKin_1	196	202	PF00069	0.503
MOD_ProDKin_1	72	78	PF00069	0.459
MOD_SUMO_for_1	115	118	PF00179	0.406
MOD_SUMO_rev_2	83	90	PF00179	0.474
TRG_ER_diArg_1	17	19	PF00400	0.573
TRG_Pf-PMV_PEXEL_1	40	44	PF00026	0.481

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYA2	Leptomonas seymouri	61%	95%
A0A3S7X226	Leishmania donovani	86%	100%
A4HH02	Leishmania braziliensis	77%	100%
A4I434	Leishmania infantum	87%	100%
Q4Q7W3	Leishmania major	89%	100%