Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0B4_LEIMU

TriTrypDb:

LmxM.28.2920

Length:

179

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0B4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0B4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	43	47	PF00082	0.538
DEG_Nend_UBRbox_2	1	3	PF02207	0.627
DOC_CKS1_1	53	58	PF01111	0.585
DOC_MAPK_gen_1	133	142	PF00069	0.677
DOC_MAPK_gen_1	63	71	PF00069	0.617
DOC_MAPK_MEF2A_6	136	144	PF00069	0.595
DOC_MAPK_MEF2A_6	15	24	PF00069	0.575
DOC_MAPK_MEF2A_6	63	71	PF00069	0.617
DOC_PP1_RVXF_1	13	20	PF00149	0.566
DOC_PP1_RVXF_1	66	72	PF00149	0.602
DOC_PP2B_LxvP_1	96	99	PF13499	0.643
DOC_PP4_FxxP_1	118	121	PF00568	0.513
DOC_PP4_FxxP_1	81	84	PF00568	0.600
DOC_USP7_MATH_1	107	111	PF00917	0.595
DOC_USP7_MATH_1	121	125	PF00917	0.627
DOC_WW_Pin1_4	142	147	PF00397	0.625
DOC_WW_Pin1_4	52	57	PF00397	0.676
LIG_14-3-3_CanoR_1	166	174	PF00244	0.614
LIG_14-3-3_CanoR_1	25	29	PF00244	0.539
LIG_Actin_WH2_2	10	27	PF00022	0.567
LIG_ActinCP_TwfCPI_2	118	125	PF01115	0.543
LIG_BIR_III_4	150	154	PF00653	0.543
LIG_FHA_1	125	131	PF00498	0.579
LIG_FHA_1	62	68	PF00498	0.480
LIG_LIR_Apic_2	116	121	PF02991	0.505
LIG_LIR_Gen_1	147	157	PF02991	0.615
LIG_LIR_Gen_1	42	53	PF02991	0.568
LIG_LIR_Nem_3	147	152	PF02991	0.614
LIG_LIR_Nem_3	18	22	PF02991	0.660
LIG_LIR_Nem_3	42	48	PF02991	0.556
LIG_PDZ_Class_2	174	179	PF00595	0.575
LIG_Pex14_2	71	75	PF04695	0.471
LIG_SH3_3	14	20	PF00018	0.581
LIG_SH3_3	50	56	PF00018	0.660
LIG_SUMO_SIM_anti_2	86	91	PF11976	0.475
LIG_SUMO_SIM_par_1	94	100	PF11976	0.505
MOD_CK1_1	100	106	PF00069	0.622
MOD_CK1_1	124	130	PF00069	0.609
MOD_CK1_1	3	9	PF00069	0.646
MOD_CK2_1	157	163	PF00069	0.713
MOD_GlcNHglycan	102	105	PF01048	0.567
MOD_GlcNHglycan	109	112	PF01048	0.704
MOD_GlcNHglycan	56	59	PF01048	0.453
MOD_GSK3_1	109	116	PF00069	0.654
MOD_GSK3_1	153	160	PF00069	0.748
MOD_GSK3_1	43	50	PF00069	0.535
MOD_NEK2_1	24	29	PF00069	0.576
MOD_NEK2_1	71	76	PF00069	0.598
MOD_PKA_2	24	30	PF00069	0.543
MOD_Plk_1	6	12	PF00069	0.607
MOD_Plk_4	113	119	PF00069	0.515
MOD_Plk_4	24	30	PF00069	0.552
MOD_ProDKin_1	142	148	PF00069	0.625
MOD_ProDKin_1	52	58	PF00069	0.672
TRG_DiLeu_BaEn_1	18	23	PF01217	0.647

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKA8	Leptomonas seymouri	48%	99%
A0A0S4J055	Bodo saltans	31%	95%
A0A1X0NR08	Trypanosomatidae	33%	87%
A0A3R7KM85	Trypanosoma rangeli	32%	100%
A0A3S7X216	Leishmania donovani	91%	100%
A4HGZ5	Leishmania braziliensis	80%	100%
A4I427	Leishmania infantum	91%	100%
D0A8Y0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
Q4Q7X0	Leishmania major	90%	99%
V5ATP2	Trypanosoma cruzi	32%	100%