LeishMANIAdb
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Putative dynein heavy chain

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative dynein heavy chain
Gene product:
dynein heavy chain, putative
Species:
Leishmania mexicana
UniProt:
E9B0B0_LEIMU
TriTrypDb:
LmxM.28.2880
Length:
4230

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 11
GO:0005874 microtubule 6 11
GO:0005875 microtubule associated complex 2 11
GO:0005930 axoneme 2 1
GO:0030286 dynein complex 3 11
GO:0032991 protein-containing complex 1 11
GO:0099080 supramolecular complex 2 11
GO:0099081 supramolecular polymer 3 11
GO:0099512 supramolecular fiber 4 11
GO:0099513 polymeric cytoskeletal fiber 5 11
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Expansion

Sequence features

E9B0B0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0007017 microtubule-based process 2 11
GO:0007018 microtubule-based movement 3 11
GO:0009987 cellular process 1 11
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Molecular functions
TermNameLevelCount
GO:0000166 nucleotide binding 3 11
GO:0003774 cytoskeletal motor activity 1 11
GO:0003777 microtubule motor activity 2 11
GO:0003824 catalytic activity 1 1
GO:0005488 binding 1 11
GO:0005515 protein binding 2 11
GO:0005524 ATP binding 5 11
GO:0008569 minus-end-directed microtubule motor activity 3 11
GO:0016787 hydrolase activity 2 1
GO:0017076 purine nucleotide binding 4 11
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 132 136 PF00656 0.433
CLV_C14_Caspase3-7 1365 1369 PF00656 0.456
CLV_C14_Caspase3-7 1612 1616 PF00656 0.410
CLV_C14_Caspase3-7 1840 1844 PF00656 0.302
CLV_C14_Caspase3-7 2327 2331 PF00656 0.386
CLV_C14_Caspase3-7 3611 3615 PF00656 0.523
CLV_C14_Caspase3-7 365 369 PF00656 0.319
CLV_C14_Caspase3-7 49 53 PF00656 0.547
CLV_NRD_NRD_1 1174 1176 PF00675 0.210
CLV_NRD_NRD_1 1231 1233 PF00675 0.230
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P5Z1 Leptomonas seymouri 82% 100%
A0A0N0P6T2 Leptomonas seymouri 32% 91%
A0A0N0P8F1 Leptomonas seymouri 34% 99%
A0A0N1I0K3 Leptomonas seymouri 33% 99%
A0A0N1I4F9 Leptomonas seymouri 34% 100%
A0A0N1I9G2 Leptomonas seymouri 26% 95%
A0A0N1PCM6 Leptomonas seymouri 27% 100%
A0A0N1PCN0 Leptomonas seymouri 32% 88%
A0A0N1PCS5 Leptomonas seymouri 36% 98%
A0A0N1PF93 Leptomonas seymouri 29% 90%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS