Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9B0A3_LEIMU

TriTrypDb:

LmxM.28.2810

Length:

207

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9B0A3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9B0A3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	131	133	PF00675	0.520
CLV_PCSK_KEX2_1	133	135	PF00082	0.517
CLV_PCSK_PC1ET2_1	133	135	PF00082	0.596
CLV_PCSK_SKI1_1	137	141	PF00082	0.570
CLV_PCSK_SKI1_1	180	184	PF00082	0.696
CLV_PCSK_SKI1_1	68	72	PF00082	0.590
DEG_SPOP_SBC_1	84	88	PF00917	0.709
DOC_MAPK_gen_1	132	141	PF00069	0.597
DOC_MAPK_gen_1	142	148	PF00069	0.617
DOC_PP1_RVXF_1	101	107	PF00149	0.579
DOC_PP1_RVXF_1	135	141	PF00149	0.594
DOC_PP1_SILK_1	155	160	PF00149	0.604
DOC_PP4_MxPP_1	1	4	PF00568	0.714
DOC_USP7_MATH_1	153	157	PF00917	0.557
DOC_USP7_MATH_1	169	173	PF00917	0.618
DOC_USP7_MATH_1	44	48	PF00917	0.684
DOC_USP7_MATH_1	51	55	PF00917	0.708
DOC_USP7_MATH_1	57	61	PF00917	0.657
DOC_USP7_MATH_1	85	89	PF00917	0.691
DOC_WW_Pin1_4	106	111	PF00397	0.566
DOC_WW_Pin1_4	96	101	PF00397	0.615
LIG_14-3-3_CanoR_1	8	13	PF00244	0.758
LIG_BIR_III_4	173	177	PF00653	0.422
LIG_BIR_III_4	93	97	PF00653	0.479
LIG_CaM_IQ_9	157	173	PF13499	0.640
LIG_FHA_1	153	159	PF00498	0.573
LIG_FHA_1	99	105	PF00498	0.570
LIG_FHA_2	147	153	PF00498	0.701
LIG_FHA_2	59	65	PF00498	0.614
LIG_Integrin_isoDGR_2	135	137	PF01839	0.636
LIG_LIR_Gen_1	7	16	PF02991	0.731
LIG_LIR_Nem_3	7	12	PF02991	0.726
LIG_PDZ_Class_3	202	207	PF00595	0.776
LIG_Pex14_2	119	123	PF04695	0.620
LIG_SH2_CRK	9	13	PF00017	0.813
LIG_SH3_1	13	19	PF00018	0.716
LIG_SH3_2	16	21	PF14604	0.517
LIG_SH3_3	13	19	PF00018	0.813
LIG_TRAF2_1	62	65	PF00917	0.624
LIG_UBA3_1	157	165	PF00899	0.599
LIG_UBA3_1	189	197	PF00899	0.585
LIG_WW_3	3	7	PF00397	0.701
MOD_CDK_SPxxK_3	96	103	PF00069	0.605
MOD_CK2_1	146	152	PF00069	0.692
MOD_CK2_1	58	64	PF00069	0.618
MOD_CK2_1	83	89	PF00069	0.782
MOD_Cter_Amidation	36	39	PF01082	0.799
MOD_GlcNHglycan	40	43	PF01048	0.720
MOD_GlcNHglycan	51	54	PF01048	0.469
MOD_GSK3_1	106	113	PF00069	0.465
MOD_GSK3_1	45	52	PF00069	0.723
MOD_N-GLC_1	96	101	PF02516	0.674
MOD_NEK2_1	146	151	PF00069	0.674
MOD_NEK2_1	193	198	PF00069	0.579
MOD_NEK2_2	178	183	PF00069	0.416
MOD_PK_1	8	14	PF00069	0.813
MOD_PKA_1	38	44	PF00069	0.797
MOD_PKA_2	121	127	PF00069	0.602
MOD_PKA_2	33	39	PF00069	0.615
MOD_PKB_1	6	14	PF00069	0.754
MOD_Plk_4	153	159	PF00069	0.573
MOD_ProDKin_1	106	112	PF00069	0.566
MOD_ProDKin_1	96	102	PF00069	0.606
MOD_SUMO_for_1	182	185	PF00179	0.632
TRG_ENDOCYTIC_2	9	12	PF00928	0.808
TRG_NLS_Bipartite_1	132	146	PF00514	0.519
TRG_NLS_MonoExtC_3	141	147	PF00514	0.543
TRG_Pf-PMV_PEXEL_1	180	185	PF00026	0.617

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE59	Leptomonas seymouri	63%	100%
A0A3S7X1Y4	Leishmania donovani	92%	100%
A0A422N0N6	Trypanosoma rangeli	43%	100%
A4HGY4	Leishmania braziliensis	78%	96%
A4I416	Leishmania infantum	91%	98%
D0A8Z3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
Q4Q7Y1	Leishmania major	90%	100%