DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

DNA helicase

Gene product:

helicase-like protein

Species:

Leishmania mexicana

UniProt:

E9AZY0_LEIMU

TriTrypDb:

LmxM.28.1600

Length:

1117

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	11
GO:0016020	membrane	2	7
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11

Expansion

Sequence features

E9AZY0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZY0

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	1
GO:0006281	DNA repair	5	1
GO:0006289	nucleotide-excision repair	6	1
GO:0006302	double-strand break repair	6	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0022402	cell cycle process	2	1
GO:0022414	reproductive process	1	1
GO:0033554	cellular response to stress	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1903046	meiotic cell cycle process	2	1
GO:1990918	double-strand break repair involved in meiotic recombination	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003678	DNA helicase activity	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0016462	pyrophosphatase activity	5	1
GO:0016887	ATP hydrolysis activity	7	1
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1029	1033	PF00656	0.732
CLV_C14_Caspase3-7	157	161	PF00656	0.524
CLV_NRD_NRD_1	1037	1039	PF00675	0.396
CLV_NRD_NRD_1	104	106	PF00675	0.502
CLV_NRD_NRD_1	111	113	PF00675	0.663
CLV_NRD_NRD_1	117	119	PF00675	0.665
CLV_NRD_NRD_1	124	126	PF00675	0.719
CLV_NRD_NRD_1	177	179	PF00675	0.731
CLV_NRD_NRD_1	194	196	PF00675	0.528
CLV_NRD_NRD_1	221	223	PF00675	0.433
CLV_NRD_NRD_1	467	469	PF00675	0.672
CLV_NRD_NRD_1	504	506	PF00675	0.560
CLV_NRD_NRD_1	521	523	PF00675	0.622
CLV_NRD_NRD_1	807	809	PF00675	0.293
CLV_NRD_NRD_1	90	92	PF00675	0.621
CLV_NRD_NRD_1	953	955	PF00675	0.367
CLV_NRD_NRD_1	978	980	PF00675	0.378
CLV_PCSK_FUR_1	102	106	PF00082	0.597
CLV_PCSK_FUR_1	465	469	PF00082	0.590
CLV_PCSK_KEX2_1	1037	1039	PF00082	0.396
CLV_PCSK_KEX2_1	104	106	PF00082	0.511
CLV_PCSK_KEX2_1	111	113	PF00082	0.664
CLV_PCSK_KEX2_1	117	119	PF00082	0.666
CLV_PCSK_KEX2_1	123	125	PF00082	0.758
CLV_PCSK_KEX2_1	193	195	PF00082	0.605
CLV_PCSK_KEX2_1	221	223	PF00082	0.481
CLV_PCSK_KEX2_1	467	469	PF00082	0.646
CLV_PCSK_KEX2_1	471	473	PF00082	0.665
CLV_PCSK_KEX2_1	504	506	PF00082	0.592
CLV_PCSK_KEX2_1	521	523	PF00082	0.651
CLV_PCSK_KEX2_1	565	567	PF00082	0.247
CLV_PCSK_KEX2_1	90	92	PF00082	0.588
CLV_PCSK_KEX2_1	953	955	PF00082	0.348
CLV_PCSK_KEX2_1	978	980	PF00082	0.378
CLV_PCSK_PC1ET2_1	117	119	PF00082	0.757
CLV_PCSK_PC1ET2_1	123	125	PF00082	0.779
CLV_PCSK_PC1ET2_1	471	473	PF00082	0.728
CLV_PCSK_PC1ET2_1	565	567	PF00082	0.247
CLV_PCSK_PC1ET2_1	90	92	PF00082	0.603
CLV_PCSK_PC7_1	467	473	PF00082	0.656
CLV_PCSK_PC7_1	517	523	PF00082	0.503
CLV_PCSK_SKI1_1	1089	1093	PF00082	0.428
CLV_PCSK_SKI1_1	1101	1105	PF00082	0.403
CLV_PCSK_SKI1_1	194	198	PF00082	0.650
CLV_PCSK_SKI1_1	382	386	PF00082	0.512
CLV_PCSK_SKI1_1	47	51	PF00082	0.500
CLV_PCSK_SKI1_1	566	570	PF00082	0.243
CLV_PCSK_SKI1_1	572	576	PF00082	0.259
CLV_PCSK_SKI1_1	586	590	PF00082	0.271
CLV_PCSK_SKI1_1	603	607	PF00082	0.428
CLV_PCSK_SKI1_1	660	664	PF00082	0.259
CLV_PCSK_SKI1_1	780	784	PF00082	0.315
CLV_PCSK_SKI1_1	854	858	PF00082	0.315
CLV_PCSK_SKI1_1	900	904	PF00082	0.322
CLV_PCSK_SKI1_1	953	957	PF00082	0.416
DEG_APCC_DBOX_1	180	188	PF00400	0.296
DEG_APCC_DBOX_1	381	389	PF00400	0.293
DEG_SCF_TRCP1_1	625	631	PF00400	0.645
DEG_SPOP_SBC_1	409	413	PF00917	0.478
DEG_SPOP_SBC_1	708	712	PF00917	0.575
DOC_CDC14_PxL_1	333	341	PF14671	0.335
DOC_CKS1_1	35	40	PF01111	0.404
DOC_CKS1_1	966	971	PF01111	0.663
DOC_CYCLIN_RxL_1	425	436	PF00134	0.385
DOC_CYCLIN_RxL_1	600	610	PF00134	0.604
DOC_CYCLIN_yCln2_LP_2	32	38	PF00134	0.417
DOC_CYCLIN_yCln2_LP_2	734	740	PF00134	0.524
DOC_CYCLIN_yCln2_LP_2	859	865	PF00134	0.535
DOC_MAPK_gen_1	178	186	PF00069	0.470
DOC_MAPK_gen_1	565	573	PF00069	0.455
DOC_MAPK_gen_1	777	785	PF00069	0.478
DOC_MAPK_gen_1	839	848	PF00069	0.437
DOC_MAPK_gen_1	900	910	PF00069	0.456
DOC_MAPK_MEF2A_6	382	389	PF00069	0.366
DOC_MAPK_MEF2A_6	565	573	PF00069	0.469
DOC_MAPK_MEF2A_6	854	863	PF00069	0.431
DOC_MAPK_NFAT4_5	382	390	PF00069	0.369
DOC_MAPK_NFAT4_5	566	574	PF00069	0.548
DOC_MAPK_NFAT4_5	854	862	PF00069	0.478
DOC_PP1_RVXF_1	321	328	PF00149	0.242
DOC_PP2B_LxvP_1	1009	1012	PF13499	0.661
DOC_PP2B_LxvP_1	197	200	PF13499	0.372
DOC_PP2B_LxvP_1	32	35	PF13499	0.397
DOC_PP2B_LxvP_1	764	767	PF13499	0.446
DOC_PP2B_LxvP_1	859	862	PF13499	0.535
DOC_PP4_FxxP_1	196	199	PF00568	0.409
DOC_PP4_FxxP_1	524	527	PF00568	0.393
DOC_PP4_FxxP_1	804	807	PF00568	0.456
DOC_PP4_FxxP_1	956	959	PF00568	0.504
DOC_USP7_MATH_1	1028	1032	PF00917	0.828
DOC_USP7_MATH_1	1054	1058	PF00917	0.716
DOC_USP7_MATH_1	1095	1099	PF00917	0.690
DOC_USP7_MATH_1	394	398	PF00917	0.388
DOC_USP7_MATH_1	409	413	PF00917	0.480
DOC_USP7_MATH_1	530	534	PF00917	0.400
DOC_USP7_MATH_1	584	588	PF00917	0.526
DOC_USP7_MATH_1	596	600	PF00917	0.619
DOC_USP7_MATH_1	708	712	PF00917	0.665
DOC_USP7_MATH_1	865	869	PF00917	0.442
DOC_USP7_UBL2_3	119	123	PF12436	0.504
DOC_WW_Pin1_4	1030	1035	PF00397	0.791
DOC_WW_Pin1_4	1064	1069	PF00397	0.687
DOC_WW_Pin1_4	20	25	PF00397	0.445
DOC_WW_Pin1_4	34	39	PF00397	0.311
DOC_WW_Pin1_4	5	10	PF00397	0.536
DOC_WW_Pin1_4	525	530	PF00397	0.326
DOC_WW_Pin1_4	666	671	PF00397	0.539
DOC_WW_Pin1_4	90	95	PF00397	0.360
DOC_WW_Pin1_4	959	964	PF00397	0.637
DOC_WW_Pin1_4	965	970	PF00397	0.637
LIG_14-3-3_CanoR_1	1017	1023	PF00244	0.751
LIG_14-3-3_CanoR_1	1042	1048	PF00244	0.736
LIG_14-3-3_CanoR_1	1055	1065	PF00244	0.632
LIG_14-3-3_CanoR_1	173	180	PF00244	0.515
LIG_14-3-3_CanoR_1	515	524	PF00244	0.479
LIG_14-3-3_CanoR_1	539	544	PF00244	0.310
LIG_14-3-3_CanoR_1	577	582	PF00244	0.474
LIG_14-3-3_CanoR_1	586	592	PF00244	0.539
LIG_14-3-3_CanoR_1	728	732	PF00244	0.580
LIG_14-3-3_CanoR_1	839	848	PF00244	0.460
LIG_14-3-3_CanoR_1	929	933	PF00244	0.606
LIG_14-3-3_CanoR_1	946	956	PF00244	0.609
LIG_Actin_WH2_2	199	216	PF00022	0.278
LIG_Actin_WH2_2	642	658	PF00022	0.507
LIG_Actin_WH2_2	740	757	PF00022	0.574
LIG_Actin_WH2_2	884	902	PF00022	0.526
LIG_APCC_ABBA_1	359	364	PF00400	0.245
LIG_APCC_ABBA_1	451	456	PF00400	0.304
LIG_BRCT_BRCA1_1	451	455	PF00533	0.270
LIG_BRCT_BRCA1_1	647	651	PF00533	0.456
LIG_deltaCOP1_diTrp_1	160	169	PF00928	0.339
LIG_DLG_GKlike_1	577	585	PF00625	0.391
LIG_EH_1	551	555	PF12763	0.266
LIG_eIF4E_1	338	344	PF01652	0.275
LIG_eIF4E_1	905	911	PF01652	0.439
LIG_EVH1_2	165	169	PF00568	0.374
LIG_FHA_1	1082	1088	PF00498	0.696
LIG_FHA_1	225	231	PF00498	0.337
LIG_FHA_1	253	259	PF00498	0.251
LIG_FHA_1	29	35	PF00498	0.424
LIG_FHA_1	411	417	PF00498	0.532
LIG_FHA_1	48	54	PF00498	0.224
LIG_FHA_1	637	643	PF00498	0.508
LIG_FHA_1	73	79	PF00498	0.286
LIG_FHA_1	749	755	PF00498	0.487
LIG_FHA_1	812	818	PF00498	0.501
LIG_FHA_1	829	835	PF00498	0.404
LIG_FHA_1	883	889	PF00498	0.498
LIG_FHA_1	998	1004	PF00498	0.710
LIG_FHA_2	1027	1033	PF00498	0.762
LIG_FHA_2	152	158	PF00498	0.566
LIG_FHA_2	346	352	PF00498	0.335
LIG_FHA_2	434	440	PF00498	0.276
LIG_FHA_2	495	501	PF00498	0.391
LIG_FHA_2	587	593	PF00498	0.529
LIG_FHA_2	751	757	PF00498	0.545
LIG_LIR_Apic_2	160	165	PF02991	0.366
LIG_LIR_Apic_2	589	594	PF02991	0.593
LIG_LIR_Apic_2	801	807	PF02991	0.525
LIG_LIR_Apic_2	912	918	PF02991	0.478
LIG_LIR_Gen_1	280	290	PF02991	0.285
LIG_LIR_Gen_1	439	448	PF02991	0.185
LIG_LIR_Gen_1	648	658	PF02991	0.479
LIG_LIR_Gen_1	730	739	PF02991	0.531
LIG_LIR_Nem_3	167	172	PF02991	0.338
LIG_LIR_Nem_3	280	285	PF02991	0.285
LIG_LIR_Nem_3	330	336	PF02991	0.245
LIG_LIR_Nem_3	439	444	PF02991	0.270
LIG_LIR_Nem_3	452	457	PF02991	0.275
LIG_LIR_Nem_3	550	554	PF02991	0.278
LIG_LIR_Nem_3	604	609	PF02991	0.549
LIG_LIR_Nem_3	648	654	PF02991	0.461
LIG_LIR_Nem_3	669	674	PF02991	0.543
LIG_LIR_Nem_3	730	734	PF02991	0.522
LIG_LIR_Nem_3	868	872	PF02991	0.478
LIG_LIR_Nem_3	904	908	PF02991	0.439
LIG_LYPXL_yS_3	336	339	PF13949	0.335
LIG_MLH1_MIPbox_1	451	455	PF16413	0.270
LIG_MYND_1	722	726	PF01753	0.552
LIG_MYND_1	965	969	PF01753	0.576
LIG_NRBOX	570	576	PF00104	0.531
LIG_Pex14_1	952	956	PF04695	0.566
LIG_Pex14_2	168	172	PF04695	0.336
LIG_PTB_Apo_2	733	740	PF02174	0.580
LIG_REV1ctd_RIR_1	166	174	PF16727	0.367
LIG_SH2_CRK	541	545	PF00017	0.231
LIG_SH2_CRK	731	735	PF00017	0.530
LIG_SH2_CRK	769	773	PF00017	0.522
LIG_SH2_CRK	905	909	PF00017	0.457
LIG_SH2_NCK_1	1078	1082	PF00017	0.639
LIG_SH2_NCK_1	328	332	PF00017	0.282
LIG_SH2_NCK_1	915	919	PF00017	0.498
LIG_SH2_SRC	328	331	PF00017	0.322
LIG_SH2_STAP1	1078	1082	PF00017	0.704
LIG_SH2_STAP1	541	545	PF00017	0.160
LIG_SH2_STAP1	699	703	PF00017	0.509
LIG_SH2_STAP1	883	887	PF00017	0.498
LIG_SH2_STAT3	100	103	PF00017	0.343
LIG_SH2_STAT3	39	42	PF00017	0.303
LIG_SH2_STAT5	100	103	PF00017	0.431
LIG_SH2_STAT5	205	208	PF00017	0.256
LIG_SH2_STAT5	241	244	PF00017	0.242
LIG_SH2_STAT5	338	341	PF00017	0.231
LIG_SH2_STAT5	883	886	PF00017	0.453
LIG_SH3_2	723	728	PF14604	0.477
LIG_SH3_2	862	867	PF14604	0.439
LIG_SH3_3	1012	1018	PF00018	0.670
LIG_SH3_3	32	38	PF00018	0.317
LIG_SH3_3	690	696	PF00018	0.537
LIG_SH3_3	720	726	PF00018	0.492
LIG_SH3_3	859	865	PF00018	0.439
LIG_SUMO_SIM_anti_2	183	189	PF11976	0.295
LIG_SUMO_SIM_anti_2	383	391	PF11976	0.347
LIG_SUMO_SIM_par_1	436	442	PF11976	0.299
LIG_SUMO_SIM_par_1	61	67	PF11976	0.316
LIG_SUMO_SIM_par_1	907	913	PF11976	0.431
LIG_TRAF2_1	1109	1112	PF00917	0.748
LIG_TRFH_1	338	342	PF08558	0.231
LIG_WRC_WIRS_1	440	445	PF05994	0.314
MOD_CDK_SPK_2	90	95	PF00069	0.439
MOD_CDK_SPxxK_3	1030	1037	PF00069	0.586
MOD_CK1_1	1026	1032	PF00069	0.810
MOD_CK1_1	1106	1112	PF00069	0.683
MOD_CK1_1	13	19	PF00069	0.527
MOD_CK1_1	408	414	PF00069	0.528
MOD_CK1_1	587	593	PF00069	0.652
MOD_CK1_1	710	716	PF00069	0.679
MOD_CK2_1	1106	1112	PF00069	0.719
MOD_CK2_1	151	157	PF00069	0.556
MOD_CK2_1	345	351	PF00069	0.335
MOD_CK2_1	387	393	PF00069	0.297
MOD_CK2_1	433	439	PF00069	0.286
MOD_CK2_1	494	500	PF00069	0.387
MOD_CK2_1	596	602	PF00069	0.756
MOD_CK2_1	750	756	PF00069	0.587
MOD_CK2_1	90	96	PF00069	0.336
MOD_GlcNHglycan	1012	1015	PF01048	0.497
MOD_GlcNHglycan	1060	1063	PF01048	0.504
MOD_GlcNHglycan	1105	1109	PF01048	0.470
MOD_GlcNHglycan	113	116	PF01048	0.702
MOD_GlcNHglycan	18	21	PF01048	0.706
MOD_GlcNHglycan	227	230	PF01048	0.439
MOD_GlcNHglycan	28	31	PF01048	0.547
MOD_GlcNHglycan	287	290	PF01048	0.506
MOD_GlcNHglycan	407	410	PF01048	0.708
MOD_GlcNHglycan	5	8	PF01048	0.766
MOD_GlcNHglycan	54	57	PF01048	0.591
MOD_GlcNHglycan	586	589	PF01048	0.386
MOD_GlcNHglycan	598	601	PF01048	0.411
MOD_GlcNHglycan	609	612	PF01048	0.492
MOD_GlcNHglycan	625	628	PF01048	0.452
MOD_GlcNHglycan	664	667	PF01048	0.260
MOD_GlcNHglycan	756	760	PF01048	0.320
MOD_GlcNHglycan	877	880	PF01048	0.231
MOD_GlcNHglycan	956	959	PF01048	0.365
MOD_GlcNHglycan	969	972	PF01048	0.506
MOD_GSK3_1	10	17	PF00069	0.522
MOD_GSK3_1	1026	1033	PF00069	0.764
MOD_GSK3_1	1054	1061	PF00069	0.682
MOD_GSK3_1	1077	1084	PF00069	0.653
MOD_GSK3_1	160	167	PF00069	0.473
MOD_GSK3_1	405	412	PF00069	0.516
MOD_GSK3_1	645	652	PF00069	0.534
MOD_GSK3_1	662	669	PF00069	0.417
MOD_GSK3_1	707	714	PF00069	0.607
MOD_GSK3_1	750	757	PF00069	0.515
MOD_GSK3_1	877	884	PF00069	0.407
MOD_GSK3_1	961	968	PF00069	0.703
MOD_GSK3_1	989	996	PF00069	0.651
MOD_LATS_1	109	115	PF00433	0.588
MOD_LATS_1	171	177	PF00433	0.422
MOD_N-GLC_1	252	257	PF02516	0.481
MOD_N-GLC_1	715	720	PF02516	0.474
MOD_N-GLC_1	821	826	PF02516	0.342
MOD_N-GLC_2	156	158	PF02516	0.559
MOD_N-GLC_2	332	334	PF02516	0.528
MOD_NEK2_1	10	15	PF00069	0.589
MOD_NEK2_1	1043	1048	PF00069	0.720
MOD_NEK2_1	1069	1074	PF00069	0.625
MOD_NEK2_1	1077	1082	PF00069	0.639
MOD_NEK2_1	1103	1108	PF00069	0.719
MOD_NEK2_1	26	31	PF00069	0.353
MOD_NEK2_1	285	290	PF00069	0.301
MOD_NEK2_1	309	314	PF00069	0.335
MOD_NEK2_1	447	452	PF00069	0.326
MOD_NEK2_1	494	499	PF00069	0.379
MOD_NEK2_1	547	552	PF00069	0.278
MOD_NEK2_1	554	559	PF00069	0.266
MOD_NEK2_1	645	650	PF00069	0.461
MOD_NEK2_1	654	659	PF00069	0.476
MOD_NEK2_1	727	732	PF00069	0.560
MOD_NEK2_1	739	744	PF00069	0.514
MOD_NEK2_1	750	755	PF00069	0.504
MOD_NEK2_1	78	83	PF00069	0.299
MOD_NEK2_1	833	838	PF00069	0.518
MOD_NEK2_1	945	950	PF00069	0.534
MOD_NEK2_1	993	998	PF00069	0.714
MOD_PIKK_1	173	179	PF00454	0.521
MOD_PIKK_1	186	192	PF00454	0.431
MOD_PIKK_1	494	500	PF00454	0.452
MOD_PIKK_1	694	700	PF00454	0.610
MOD_PIKK_1	717	723	PF00454	0.726
MOD_PIKK_1	748	754	PF00454	0.552
MOD_PIKK_1	798	804	PF00454	0.490
MOD_PIKK_1	821	827	PF00454	0.545
MOD_PIKK_1	947	953	PF00454	0.484
MOD_PK_1	539	545	PF00069	0.160
MOD_PKA_1	111	117	PF00069	0.541
MOD_PKA_2	1054	1060	PF00069	0.717
MOD_PKA_2	111	117	PF00069	0.564
MOD_PKA_2	473	479	PF00069	0.383
MOD_PKA_2	636	642	PF00069	0.442
MOD_PKA_2	727	733	PF00069	0.594
MOD_PKA_2	754	760	PF00069	0.513
MOD_PKA_2	922	928	PF00069	0.474
MOD_PKA_2	945	951	PF00069	0.627
MOD_PKB_1	995	1003	PF00069	0.723
MOD_Plk_1	252	258	PF00069	0.313
MOD_Plk_1	601	607	PF00069	0.719
MOD_Plk_1	934	940	PF00069	0.576
MOD_Plk_1	988	994	PF00069	0.574
MOD_Plk_2-3	374	380	PF00069	0.242
MOD_Plk_4	164	170	PF00069	0.381
MOD_Plk_4	199	205	PF00069	0.271
MOD_Plk_4	449	455	PF00069	0.364
MOD_Plk_4	539	545	PF00069	0.225
MOD_Plk_4	559	565	PF00069	0.224
MOD_Plk_4	78	84	PF00069	0.300
MOD_ProDKin_1	1030	1036	PF00069	0.791
MOD_ProDKin_1	1064	1070	PF00069	0.679
MOD_ProDKin_1	20	26	PF00069	0.444
MOD_ProDKin_1	34	40	PF00069	0.313
MOD_ProDKin_1	5	11	PF00069	0.535
MOD_ProDKin_1	525	531	PF00069	0.323
MOD_ProDKin_1	666	672	PF00069	0.545
MOD_ProDKin_1	90	96	PF00069	0.360
MOD_ProDKin_1	959	965	PF00069	0.639
TRG_DiLeu_BaEn_2	438	444	PF01217	0.314
TRG_DiLeu_BaLyEn_6	21	26	PF01217	0.351
TRG_DiLeu_BaLyEn_6	339	344	PF01217	0.242
TRG_DiLeu_BaLyEn_6	720	725	PF01217	0.655
TRG_DiLeu_BaLyEn_6	962	967	PF01217	0.567
TRG_ENDOCYTIC_2	282	285	PF00928	0.266
TRG_ENDOCYTIC_2	328	331	PF00928	0.244
TRG_ENDOCYTIC_2	336	339	PF00928	0.219
TRG_ENDOCYTIC_2	541	544	PF00928	0.231
TRG_ENDOCYTIC_2	731	734	PF00928	0.475
TRG_ENDOCYTIC_2	769	772	PF00928	0.442
TRG_ENDOCYTIC_2	905	908	PF00928	0.439
TRG_ER_diArg_1	101	104	PF00400	0.359
TRG_ER_diArg_1	111	113	PF00400	0.468
TRG_ER_diArg_1	192	195	PF00400	0.382
TRG_ER_diArg_1	220	222	PF00400	0.298
TRG_ER_diArg_1	503	505	PF00400	0.393
TRG_ER_diArg_1	514	517	PF00400	0.445
TRG_ER_diArg_1	952	954	PF00400	0.528
TRG_ER_diArg_1	977	979	PF00400	0.669
TRG_ER_diArg_1	995	998	PF00400	0.747
TRG_NES_CRM1_1	300	310	PF08389	0.303
TRG_NES_CRM1_1	391	405	PF08389	0.397
TRG_NES_CRM1_1	449	463	PF08389	0.293
TRG_NES_CRM1_1	850	864	PF08389	0.439
TRG_NLS_Bipartite_1	111	127	PF00514	0.554
TRG_NLS_MonoExtC_3	177	183	PF00514	0.391
TRG_NLS_MonoExtC_3	89	94	PF00514	0.458
TRG_NLS_MonoExtN_4	121	127	PF00514	0.453
TRG_Pf-PMV_PEXEL_1	105	110	PF00026	0.588
TRG_Pf-PMV_PEXEL_1	1075	1079	PF00026	0.394
TRG_Pf-PMV_PEXEL_1	47	51	PF00026	0.514
TRG_Pf-PMV_PEXEL_1	572	576	PF00026	0.301
TRG_Pf-PMV_PEXEL_1	676	681	PF00026	0.329

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8F0	Leptomonas seymouri	57%	88%
A0A0S4IQT3	Bodo saltans	38%	100%
A0A1X0NRE3	Trypanosomatidae	42%	100%
A0A3R7P0G4	Trypanosoma rangeli	43%	100%
A0A3S5H7J4	Leishmania donovani	90%	100%
A4HGL3	Leishmania braziliensis	79%	100%
A4I3N9	Leishmania infantum	89%	88%
D0A8C5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
Q4Q8A5	Leishmania major	90%	100%
V5BAP9	Trypanosoma cruzi	39%	100%