Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AZX1_LEIMU

TriTrypDb:

LmxM.28.1515

Length:

164

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZX1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZX1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	147	151	PF00656	0.641
CLV_NRD_NRD_1	137	139	PF00675	0.723
CLV_NRD_NRD_1	159	161	PF00675	0.762
CLV_NRD_NRD_1	78	80	PF00675	0.710
CLV_PCSK_KEX2_1	137	139	PF00082	0.723
CLV_PCSK_KEX2_1	158	160	PF00082	0.680
CLV_PCSK_KEX2_1	78	80	PF00082	0.710
CLV_PCSK_SKI1_1	18	22	PF00082	0.613
DEG_APCC_DBOX_1	77	85	PF00400	0.523
DEG_SCF_FBW7_1	93	100	PF00400	0.529
DOC_MAPK_gen_1	158	164	PF00069	0.687
DOC_USP7_MATH_1	103	107	PF00917	0.574
DOC_USP7_MATH_1	14	18	PF00917	0.786
DOC_USP7_MATH_1	77	81	PF00917	0.788
DOC_USP7_MATH_1	91	95	PF00917	0.574
DOC_USP7_MATH_1	97	101	PF00917	0.639
DOC_WW_Pin1_4	68	73	PF00397	0.516
DOC_WW_Pin1_4	93	98	PF00397	0.614
LIG_14-3-3_CanoR_1	59	68	PF00244	0.818
LIG_14-3-3_CanoR_1	78	82	PF00244	0.600
LIG_BIR_II_1	1	5	PF00653	0.814
LIG_FHA_1	39	45	PF00498	0.641
LIG_TRAF2_1	151	154	PF00917	0.703
LIG_TRAF2_1	46	49	PF00917	0.524
MOD_CK1_1	110	116	PF00069	0.692
MOD_CK2_1	116	122	PF00069	0.681
MOD_CK2_1	148	154	PF00069	0.783
MOD_CK2_1	37	43	PF00069	0.662
MOD_GlcNHglycan	61	64	PF01048	0.824
MOD_GlcNHglycan	73	76	PF01048	0.662
MOD_GlcNHglycan	86	89	PF01048	0.640
MOD_GlcNHglycan	99	102	PF01048	0.667
MOD_GSK3_1	103	110	PF00069	0.654
MOD_GSK3_1	14	21	PF00069	0.748
MOD_GSK3_1	148	155	PF00069	0.780
MOD_GSK3_1	66	73	PF00069	0.760
MOD_GSK3_1	93	100	PF00069	0.669
MOD_LATS_1	57	63	PF00433	0.725
MOD_N-GLC_1	66	71	PF02516	0.811
MOD_NEK2_1	84	89	PF00069	0.537
MOD_PKA_2	77	83	PF00069	0.709
MOD_Plk_1	152	158	PF00069	0.700
MOD_Plk_2-3	148	154	PF00069	0.783
MOD_Plk_2-3	38	44	PF00069	0.757
MOD_ProDKin_1	68	74	PF00069	0.516
MOD_ProDKin_1	93	99	PF00069	0.614
TRG_ER_diArg_1	136	138	PF00400	0.725
TRG_ER_diArg_1	158	160	PF00400	0.680
TRG_ER_diArg_1	77	79	PF00400	0.711
TRG_Pf-PMV_PEXEL_1	137	141	PF00026	0.727

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIA3	Leptomonas seymouri	41%	100%
A0A3S7X1K8	Leishmania donovani	88%	99%
A4HGK4	Leishmania braziliensis	68%	99%
A4I3N0	Leishmania infantum	88%	99%
Q4Q8B4	Leishmania major	80%	96%