LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AZV2_LEIMU
TriTrypDb:
LmxM.28.1330
Length:
336

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0005929 cilium 4 6
GO:0042995 cell projection 2 6
GO:0043226 organelle 2 6
GO:0043227 membrane-bounded organelle 3 6
GO:0110165 cellular anatomical entity 1 6
GO:0120025 plasma membrane bounded cell projection 3 6

Expansion

Sequence features

E9AZV2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZV2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 100 102 PF00675 0.668
CLV_NRD_NRD_1 183 185 PF00675 0.563
CLV_NRD_NRD_1 289 291 PF00675 0.479
CLV_NRD_NRD_1 324 326 PF00675 0.505
CLV_NRD_NRD_1 50 52 PF00675 0.778
CLV_NRD_NRD_1 91 93 PF00675 0.800
CLV_PCSK_KEX2_1 100 102 PF00082 0.671
CLV_PCSK_KEX2_1 183 185 PF00082 0.563
CLV_PCSK_KEX2_1 289 291 PF00082 0.479
CLV_PCSK_KEX2_1 324 326 PF00082 0.505
CLV_PCSK_KEX2_1 50 52 PF00082 0.778
CLV_PCSK_KEX2_1 91 93 PF00082 0.822
DEG_APCC_DBOX_1 113 121 PF00400 0.553
DEG_APCC_DBOX_1 165 173 PF00400 0.593
DEG_SCF_FBW7_1 15 21 PF00400 0.601
DOC_CKS1_1 15 20 PF01111 0.635
DOC_MAPK_gen_1 286 294 PF00069 0.533
DOC_MAPK_MEF2A_6 218 227 PF00069 0.480
DOC_USP7_MATH_1 129 133 PF00917 0.840
DOC_USP7_MATH_1 154 158 PF00917 0.782
DOC_USP7_MATH_1 264 268 PF00917 0.581
DOC_USP7_MATH_1 42 46 PF00917 0.844
DOC_USP7_UBL2_3 312 316 PF12436 0.352
DOC_WW_Pin1_4 11 16 PF00397 0.666
DOC_WW_Pin1_4 119 124 PF00397 0.701
DOC_WW_Pin1_4 150 155 PF00397 0.683
DOC_WW_Pin1_4 18 23 PF00397 0.642
DOC_WW_Pin1_4 58 63 PF00397 0.687
LIG_14-3-3_CanoR_1 128 137 PF00244 0.660
LIG_14-3-3_CanoR_1 166 170 PF00244 0.537
LIG_14-3-3_CanoR_1 176 181 PF00244 0.442
LIG_14-3-3_CanoR_1 43 47 PF00244 0.685
LIG_Actin_WH2_2 287 304 PF00022 0.615
LIG_BIR_II_1 1 5 PF00653 0.734
LIG_FHA_1 222 228 PF00498 0.565
LIG_FHA_1 273 279 PF00498 0.583
LIG_FHA_1 77 83 PF00498 0.750
LIG_FHA_2 229 235 PF00498 0.574
LIG_FHA_2 35 41 PF00498 0.675
LIG_Integrin_RGD_1 101 103 PF01839 0.565
LIG_LIR_Gen_1 234 243 PF02991 0.576
LIG_LIR_Nem_3 234 238 PF02991 0.565
LIG_SH2_CRK 191 195 PF00017 0.338
LIG_SH2_PTP2 235 238 PF00017 0.559
LIG_SH2_SRC 214 217 PF00017 0.598
LIG_SH2_STAT5 173 176 PF00017 0.577
LIG_SH2_STAT5 214 217 PF00017 0.437
LIG_SH2_STAT5 229 232 PF00017 0.459
LIG_SH2_STAT5 235 238 PF00017 0.376
LIG_SH3_3 117 123 PF00018 0.831
LIG_SH3_3 12 18 PF00018 0.747
LIG_SH3_3 222 228 PF00018 0.565
LIG_SH3_3 77 83 PF00018 0.672
LIG_SUMO_SIM_par_1 274 279 PF11976 0.585
LIG_SUMO_SIM_par_1 78 84 PF11976 0.577
LIG_TYR_ITIM 233 238 PF00017 0.563
LIG_WW_3 66 70 PF00397 0.680
MOD_CDK_SPK_2 119 124 PF00069 0.701
MOD_CDK_SPK_2 18 23 PF00069 0.707
MOD_CK1_1 122 128 PF00069 0.707
MOD_CK1_1 14 20 PF00069 0.728
MOD_CK1_1 159 165 PF00069 0.618
MOD_CK1_1 168 174 PF00069 0.501
MOD_CK1_1 21 27 PF00069 0.772
MOD_CK1_1 28 34 PF00069 0.751
MOD_CK1_1 84 90 PF00069 0.639
MOD_CK2_1 228 234 PF00069 0.578
MOD_Cter_Amidation 287 290 PF01082 0.531
MOD_GlcNHglycan 131 134 PF01048 0.758
MOD_GlcNHglycan 156 159 PF01048 0.678
MOD_GlcNHglycan 246 249 PF01048 0.726
MOD_GlcNHglycan 266 269 PF01048 0.557
MOD_GlcNHglycan 30 33 PF01048 0.735
MOD_GlcNHglycan 44 47 PF01048 0.616
MOD_GlcNHglycan 52 55 PF01048 0.730
MOD_GSK3_1 115 122 PF00069 0.732
MOD_GSK3_1 123 130 PF00069 0.690
MOD_GSK3_1 14 21 PF00069 0.644
MOD_GSK3_1 150 157 PF00069 0.784
MOD_GSK3_1 168 175 PF00069 0.339
MOD_GSK3_1 244 251 PF00069 0.682
MOD_GSK3_1 272 279 PF00069 0.516
MOD_GSK3_1 30 37 PF00069 0.788
MOD_GSK3_1 324 331 PF00069 0.533
MOD_GSK3_1 81 88 PF00069 0.602
MOD_NEK2_1 172 177 PF00069 0.573
MOD_NEK2_1 76 81 PF00069 0.752
MOD_PK_1 92 98 PF00069 0.557
MOD_PKA_1 324 330 PF00069 0.511
MOD_PKA_1 50 56 PF00069 0.776
MOD_PKA_2 127 133 PF00069 0.670
MOD_PKA_2 165 171 PF00069 0.621
MOD_PKA_2 210 216 PF00069 0.609
MOD_PKA_2 324 330 PF00069 0.511
MOD_PKA_2 34 40 PF00069 0.652
MOD_PKA_2 42 48 PF00069 0.725
MOD_PKA_2 50 56 PF00069 0.734
MOD_PKA_2 85 91 PF00069 0.810
MOD_Plk_1 276 282 PF00069 0.597
MOD_Plk_4 137 143 PF00069 0.716
MOD_Plk_4 210 216 PF00069 0.609
MOD_Plk_4 221 227 PF00069 0.562
MOD_Plk_4 4 10 PF00069 0.735
MOD_Plk_4 76 82 PF00069 0.670
MOD_ProDKin_1 11 17 PF00069 0.665
MOD_ProDKin_1 119 125 PF00069 0.700
MOD_ProDKin_1 150 156 PF00069 0.682
MOD_ProDKin_1 18 24 PF00069 0.644
MOD_ProDKin_1 58 64 PF00069 0.684
TRG_DiLeu_BaLyEn_6 107 112 PF01217 0.625
TRG_ENDOCYTIC_2 235 238 PF00928 0.407
TRG_ER_diArg_1 182 184 PF00400 0.561
TRG_ER_diArg_1 289 291 PF00400 0.541
TRG_ER_diArg_1 323 325 PF00400 0.484
TRG_ER_diArg_1 90 92 PF00400 0.815

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IDS7 Leishmania donovani 90% 96%
A4HGI0 Leishmania braziliensis 63% 97%
A4I3L2 Leishmania infantum 90% 96%
Q4Q8D3 Leishmania major 87% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS