LeishMANIAdb
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Serine incorporator

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Serine incorporator
Gene product:
Serine incorporator (Serinc), putative
Species:
Leishmania mexicana
UniProt:
E9AZR5_LEIMU
TriTrypDb:
LmxM.28.0990
Length:
416

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 12
NetGPI no yes: 0, no: 12
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 13
GO:0110165 cellular anatomical entity 1 13
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Expansion

Sequence features

E9AZR5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZR5

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 179 183 PF00656 0.514
CLV_C14_Caspase3-7 3 7 PF00656 0.548
CLV_MEL_PAP_1 83 89 PF00089 0.314
CLV_NRD_NRD_1 12 14 PF00675 0.540
CLV_PCSK_KEX2_1 12 14 PF00082 0.521
CLV_PCSK_SKI1_1 119 123 PF00082 0.262
CLV_PCSK_SKI1_1 125 129 PF00082 0.308
CLV_PCSK_SKI1_1 276 280 PF00082 0.558
DEG_COP1_1 2 11 PF00400 0.546
DEG_MDM2_SWIB_1 389 396 PF02201 0.399
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HS92 Leptomonas seymouri 75% 100%
A0A0S4JS67 Bodo saltans 40% 90%
A0A0S4KHE1 Bodo saltans 30% 100%
A0A1X0NWP2 Trypanosomatidae 53% 100%
A0A3Q8II09 Leishmania donovani 93% 100%
A0A3R7M259 Trypanosoma rangeli 53% 100%
A4FUZ5 Bos taurus 22% 88%
A4HGE3 Leishmania braziliensis 84% 100%
A4I3H6 Leishmania infantum 93% 100%
A7S4N4 Nematostella vectensis 23% 91%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS