LeishMANIAdb
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Type VI secretion protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Type VI secretion protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AZR4_LEIMU
TriTrypDb:
LmxM.28.0980
Length:
240

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 16
NetGPI no yes: 0, no: 16
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 10
GO:0110165 cellular anatomical entity 1 10
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Expansion

Sequence features

E9AZR4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZR4

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_PCSK_SKI1_1 200 204 PF00082 0.706
DOC_CYCLIN_RxL_1 194 208 PF00134 0.411
DOC_PP1_RVXF_1 120 126 PF00149 0.416
DOC_PP1_RVXF_1 49 56 PF00149 0.622
DOC_PP1_RVXF_1 78 85 PF00149 0.642
DOC_PP2B_PxIxI_1 127 133 PF00149 0.324
DOC_PP4_FxxP_1 125 128 PF00568 0.431
DOC_USP7_MATH_1 233 237 PF00917 0.529
DOC_USP7_MATH_1 26 30 PF00917 0.562
LIG_14-3-3_CanoR_1 122 126 PF00244 0.458
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HYK0 Leptomonas seymouri 62% 99%
A0A0S4IVH5 Bodo saltans 47% 99%
A0A0S4IXX7 Bodo saltans 47% 91%
A0A1X0NYZ9 Trypanosomatidae 62% 100%
A0A3Q8IGT4 Leishmania donovani 60% 99%
A0A422MZK8 Trypanosoma rangeli 60% 100%
A4HGE2 Leishmania braziliensis 80% 100%
A4HLG1 Leishmania braziliensis 57% 100%
A4I3H5 Leishmania infantum 91% 100%
A4I8X2 Leishmania infantum 60% 99%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS