LSM domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AZR3_LEIMU

TriTrypDb:

LmxM.28.0970

Length:

151

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZR3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZR3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	124	126	PF00675	0.493
CLV_NRD_NRD_1	46	48	PF00675	0.434
CLV_PCSK_KEX2_1	124	126	PF00082	0.530
CLV_PCSK_KEX2_1	46	48	PF00082	0.434
CLV_PCSK_SKI1_1	46	50	PF00082	0.493
DEG_SPOP_SBC_1	22	26	PF00917	0.483
DOC_CKS1_1	142	147	PF01111	0.545
DOC_MAPK_gen_1	28	35	PF00069	0.632
DOC_MAPK_gen_1	46	52	PF00069	0.433
DOC_USP7_MATH_1	21	25	PF00917	0.642
DOC_USP7_MATH_1	85	89	PF00917	0.665
DOC_WW_Pin1_4	141	146	PF00397	0.464
LIG_14-3-3_CanoR_1	129	135	PF00244	0.513
LIG_14-3-3_CanoR_1	46	51	PF00244	0.511
LIG_14-3-3_CanoR_1	80	84	PF00244	0.527
LIG_BIR_II_1	1	5	PF00653	0.594
LIG_FHA_1	142	148	PF00498	0.511
LIG_FHA_1	47	53	PF00498	0.520
LIG_FHA_2	108	114	PF00498	0.635
LIG_LIR_Gen_1	137	147	PF02991	0.455
LIG_LIR_Gen_1	38	48	PF02991	0.532
LIG_LIR_Nem_3	113	119	PF02991	0.515
LIG_LIR_Nem_3	137	142	PF02991	0.483
LIG_LIR_Nem_3	38	44	PF02991	0.486
LIG_PTAP_UEV_1	17	22	PF05743	0.562
LIG_PTB_Apo_2	133	140	PF02174	0.440
LIG_SH2_STAP1	37	41	PF00017	0.542
LIG_SH2_STAT5	81	84	PF00017	0.550
LIG_SH3_1	15	21	PF00018	0.700
LIG_SH3_3	144	150	PF00018	0.450
LIG_SH3_3	15	21	PF00018	0.752
LIG_SUMO_SIM_par_1	48	53	PF11976	0.475
LIG_TRAF2_1	110	113	PF00917	0.725
LIG_TRAF2_1	89	92	PF00917	0.760
LIG_TYR_ITIM	35	40	PF00017	0.549
MOD_CK1_1	128	134	PF00069	0.521
MOD_CK1_1	26	32	PF00069	0.623
MOD_CK1_1	65	71	PF00069	0.545
MOD_CK1_1	8	14	PF00069	0.713
MOD_CK1_1	86	92	PF00069	0.683
MOD_CK2_1	105	111	PF00069	0.424
MOD_CK2_1	85	91	PF00069	0.741
MOD_Cter_Amidation	44	47	PF01082	0.451
MOD_GlcNHglycan	1	4	PF01048	0.623
MOD_GlcNHglycan	136	139	PF01048	0.468
MOD_GlcNHglycan	18	21	PF01048	0.641
MOD_GlcNHglycan	25	28	PF01048	0.734
MOD_GlcNHglycan	7	10	PF01048	0.626
MOD_GSK3_1	22	29	PF00069	0.711
MOD_GSK3_1	46	53	PF00069	0.515
MOD_GSK3_1	79	86	PF00069	0.574
MOD_GSK3_1	91	98	PF00069	0.721
MOD_N-GLC_1	5	10	PF02516	0.699
MOD_NEK2_1	134	139	PF00069	0.460
MOD_NEK2_1	59	64	PF00069	0.521
MOD_PIKK_1	128	134	PF00454	0.521
MOD_PIKK_1	53	59	PF00454	0.630
MOD_PKA_1	46	52	PF00069	0.514
MOD_PKA_2	11	17	PF00069	0.697
MOD_PKA_2	128	134	PF00069	0.502
MOD_PKA_2	46	52	PF00069	0.450
MOD_PKA_2	79	85	PF00069	0.613
MOD_PKA_2	86	92	PF00069	0.662
MOD_Plk_4	143	149	PF00069	0.573
MOD_Plk_4	46	52	PF00069	0.475
MOD_ProDKin_1	141	147	PF00069	0.514
TRG_ENDOCYTIC_2	116	119	PF00928	0.593
TRG_ENDOCYTIC_2	37	40	PF00928	0.499
TRG_ER_diArg_1	46	48	PF00400	0.434

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHV6	Leptomonas seymouri	62%	93%
A0A1X0NYE6	Trypanosomatidae	34%	100%
A0A3Q8ID22	Leishmania donovani	91%	92%
A0A422MZL4	Trypanosoma rangeli	37%	100%
A4HGE1	Leishmania braziliensis	75%	100%
A4I3H4	Leishmania infantum	91%	92%
Q4Q8H0	Leishmania major	87%	100%