Ribonucleoside-diphosphate reductase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribonucleoside-diphosphate reductase large chain, putative

Species:

Leishmania mexicana

UniProt:

E9AZQ5_LEIMU

TriTrypDb:

LmxM.28.0890

Length:

799

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005971	ribonucleoside-diphosphate reductase complex	4	1
GO:0032991	protein-containing complex	1	1
GO:1902494	catalytic complex	2	1
GO:1990204	oxidoreductase complex	3	1

Expansion

Sequence features

E9AZQ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZQ5

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006260	DNA replication	5	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0006753	nucleoside phosphate metabolic process	4	1
GO:0006793	phosphorus metabolic process	3	1
GO:0006796	phosphate-containing compound metabolic process	4	1
GO:0009058	biosynthetic process	2	1
GO:0009117	nucleotide metabolic process	5	1
GO:0009165	nucleotide biosynthetic process	6	1
GO:0009262	deoxyribonucleotide metabolic process	4	1
GO:0009263	deoxyribonucleotide biosynthetic process	5	1
GO:0018130	heterocycle biosynthetic process	4	1
GO:0019438	aromatic compound biosynthetic process	4	1
GO:0019637	organophosphate metabolic process	3	1
GO:0034654	nucleobase-containing compound biosynthetic process	4	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0044281	small molecule metabolic process	2	1
GO:0055086	nucleobase-containing small molecule metabolic process	3	1
GO:0090407	organophosphate biosynthetic process	4	1
GO:1901135	carbohydrate derivative metabolic process	3	1
GO:1901137	carbohydrate derivative biosynthetic process	4	1
GO:1901293	nucleoside phosphate biosynthetic process	5	1
GO:1901362	organic cyclic compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	6	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016491	oxidoreductase activity	2	12
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3	12
GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0061731	ribonucleoside-diphosphate reductase activity	5	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	236	240	PF00656	0.388
CLV_NRD_NRD_1	25	27	PF00675	0.370
CLV_NRD_NRD_1	302	304	PF00675	0.294
CLV_NRD_NRD_1	350	352	PF00675	0.315
CLV_NRD_NRD_1	640	642	PF00675	0.294
CLV_NRD_NRD_1	701	703	PF00675	0.439
CLV_NRD_NRD_1	786	788	PF00675	0.535
CLV_PCSK_KEX2_1	10	12	PF00082	0.281
CLV_PCSK_KEX2_1	24	26	PF00082	0.344
CLV_PCSK_KEX2_1	302	304	PF00082	0.294
CLV_PCSK_KEX2_1	325	327	PF00082	0.388
CLV_PCSK_KEX2_1	350	352	PF00082	0.359
CLV_PCSK_KEX2_1	469	471	PF00082	0.439
CLV_PCSK_KEX2_1	640	642	PF00082	0.294
CLV_PCSK_KEX2_1	768	770	PF00082	0.631
CLV_PCSK_KEX2_1	786	788	PF00082	0.500
CLV_PCSK_PC1ET2_1	10	12	PF00082	0.270
CLV_PCSK_PC1ET2_1	302	304	PF00082	0.294
CLV_PCSK_PC1ET2_1	325	327	PF00082	0.388
CLV_PCSK_PC1ET2_1	469	471	PF00082	0.439
CLV_PCSK_PC1ET2_1	768	770	PF00082	0.631
CLV_PCSK_SKI1_1	183	187	PF00082	0.294
CLV_PCSK_SKI1_1	205	209	PF00082	0.440
CLV_PCSK_SKI1_1	304	308	PF00082	0.294
CLV_PCSK_SKI1_1	336	340	PF00082	0.294
CLV_PCSK_SKI1_1	350	354	PF00082	0.294
CLV_PCSK_SKI1_1	389	393	PF00082	0.363
CLV_PCSK_SKI1_1	482	486	PF00082	0.334
CLV_PCSK_SKI1_1	50	54	PF00082	0.330
CLV_PCSK_SKI1_1	640	644	PF00082	0.294
CLV_PCSK_SKI1_1	768	772	PF00082	0.559
DEG_APCC_DBOX_1	157	165	PF00400	0.294
DOC_ANK_TNKS_1	507	514	PF00023	0.314
DOC_MAPK_gen_1	302	311	PF00069	0.294
DOC_MAPK_gen_1	508	516	PF00069	0.328
DOC_MAPK_gen_1	598	606	PF00069	0.358
DOC_MAPK_HePTP_8	250	262	PF00069	0.309
DOC_MAPK_JIP1_4	510	516	PF00069	0.388
DOC_MAPK_MEF2A_6	253	262	PF00069	0.294
DOC_MAPK_MEF2A_6	36	43	PF00069	0.550
DOC_MAPK_MEF2A_6	508	516	PF00069	0.328
DOC_MAPK_MEF2A_6	598	606	PF00069	0.439
DOC_PP1_RVXF_1	142	149	PF00149	0.495
DOC_PP2B_LxvP_1	342	345	PF13499	0.294
DOC_PP2B_LxvP_1	611	614	PF13499	0.274
DOC_USP7_MATH_1	223	227	PF00917	0.349
DOC_USP7_MATH_1	267	271	PF00917	0.388
DOC_USP7_MATH_1	420	424	PF00917	0.359
DOC_USP7_MATH_1	502	506	PF00917	0.328
DOC_USP7_MATH_1	529	533	PF00917	0.388
DOC_USP7_MATH_1	550	554	PF00917	0.359
DOC_USP7_MATH_1	616	620	PF00917	0.294
DOC_USP7_MATH_1	632	636	PF00917	0.294
DOC_USP7_UBL2_3	353	357	PF12436	0.334
DOC_USP7_UBL2_3	424	428	PF12436	0.294
DOC_WW_Pin1_4	209	214	PF00397	0.294
DOC_WW_Pin1_4	217	222	PF00397	0.294
DOC_WW_Pin1_4	444	449	PF00397	0.358
DOC_WW_Pin1_4	567	572	PF00397	0.294
DOC_WW_Pin1_4	724	729	PF00397	0.388
LIG_14-3-3_CanoR_1	350	360	PF00244	0.442
LIG_14-3-3_CanoR_1	50	58	PF00244	0.563
LIG_14-3-3_CanoR_1	607	611	PF00244	0.294
LIG_14-3-3_CanoR_1	786	791	PF00244	0.638
LIG_Actin_WH2_2	179	196	PF00022	0.315
LIG_Actin_WH2_2	594	609	PF00022	0.195
LIG_Actin_WH2_2	730	748	PF00022	0.461
LIG_APCC_ABBA_1	307	312	PF00400	0.294
LIG_APCC_ABBA_1	414	419	PF00400	0.309
LIG_BIR_II_1	1	5	PF00653	0.597
LIG_BRCT_BRCA1_1	146	150	PF00533	0.195
LIG_BRCT_BRCA1_1	203	207	PF00533	0.353
LIG_BRCT_BRCA1_1	225	229	PF00533	0.294
LIG_BRCT_BRCA1_1	643	647	PF00533	0.303
LIG_BRCT_BRCA1_1	734	738	PF00533	0.294
LIG_Clathr_ClatBox_1	161	165	PF01394	0.309
LIG_CSL_BTD_1	342	345	PF09270	0.294
LIG_deltaCOP1_diTrp_1	312	321	PF00928	0.294
LIG_EH1_1	652	660	PF00400	0.294
LIG_eIF4E_1	653	659	PF01652	0.309
LIG_FHA_1	100	106	PF00498	0.308
LIG_FHA_1	197	203	PF00498	0.355
LIG_FHA_1	210	216	PF00498	0.283
LIG_FHA_1	43	49	PF00498	0.480
LIG_FHA_1	438	444	PF00498	0.309
LIG_FHA_1	479	485	PF00498	0.311
LIG_FHA_1	51	57	PF00498	0.450
LIG_FHA_1	618	624	PF00498	0.294
LIG_FHA_1	632	638	PF00498	0.294
LIG_FHA_1	732	738	PF00498	0.448
LIG_FHA_1	86	92	PF00498	0.513
LIG_FHA_2	242	248	PF00498	0.439
LIG_FHA_2	326	332	PF00498	0.294
LIG_FHA_2	357	363	PF00498	0.294
LIG_FHA_2	693	699	PF00498	0.452
LIG_LIR_Apic_2	444	448	PF02991	0.358
LIG_LIR_Apic_2	580	585	PF02991	0.268
LIG_LIR_Apic_2	695	700	PF02991	0.439
LIG_LIR_Gen_1	145	156	PF02991	0.294
LIG_LIR_Gen_1	198	208	PF02991	0.294
LIG_LIR_Gen_1	239	250	PF02991	0.294
LIG_LIR_Gen_1	355	363	PF02991	0.333
LIG_LIR_Gen_1	375	384	PF02991	0.496
LIG_LIR_Gen_1	398	408	PF02991	0.294
LIG_LIR_Gen_1	521	531	PF02991	0.309
LIG_LIR_Gen_1	541	551	PF02991	0.326
LIG_LIR_Gen_1	561	572	PF02991	0.176
LIG_LIR_Gen_1	593	602	PF02991	0.309
LIG_LIR_Nem_3	101	106	PF02991	0.414
LIG_LIR_Nem_3	145	151	PF02991	0.294
LIG_LIR_Nem_3	239	245	PF02991	0.294
LIG_LIR_Nem_3	317	322	PF02991	0.294
LIG_LIR_Nem_3	337	342	PF02991	0.173
LIG_LIR_Nem_3	375	380	PF02991	0.343
LIG_LIR_Nem_3	398	404	PF02991	0.294
LIG_LIR_Nem_3	493	499	PF02991	0.316
LIG_LIR_Nem_3	541	546	PF02991	0.326
LIG_LIR_Nem_3	561	567	PF02991	0.176
LIG_LIR_Nem_3	593	597	PF02991	0.309
LIG_LIR_Nem_3	628	633	PF02991	0.353
LIG_LIR_Nem_3	644	650	PF02991	0.290
LIG_LIR_Nem_3	691	696	PF02991	0.294
LIG_PALB2_WD40_1	396	404	PF16756	0.294
LIG_Pex14_2	339	343	PF04695	0.294
LIG_REV1ctd_RIR_1	148	158	PF16727	0.328
LIG_SH2_CRK	242	246	PF00017	0.294
LIG_SH2_CRK	445	449	PF00017	0.261
LIG_SH2_NCK_1	445	449	PF00017	0.358
LIG_SH2_SRC	310	313	PF00017	0.294
LIG_SH2_STAP1	142	146	PF00017	0.362
LIG_SH2_STAP1	340	344	PF00017	0.328
LIG_SH2_STAT3	295	298	PF00017	0.294
LIG_SH2_STAT3	714	717	PF00017	0.328
LIG_SH2_STAT5	160	163	PF00017	0.358
LIG_SH2_STAT5	271	274	PF00017	0.294
LIG_SH2_STAT5	295	298	PF00017	0.294
LIG_SH2_STAT5	310	313	PF00017	0.294
LIG_SH2_STAT5	445	448	PF00017	0.309
LIG_SH2_STAT5	478	481	PF00017	0.408
LIG_SH2_STAT5	547	550	PF00017	0.388
LIG_SH2_STAT5	638	641	PF00017	0.303
LIG_SH2_STAT5	653	656	PF00017	0.406
LIG_SH2_STAT5	714	717	PF00017	0.354
LIG_SH2_STAT5	739	742	PF00017	0.292
LIG_SH2_STAT5	751	754	PF00017	0.356
LIG_SH3_3	171	177	PF00018	0.309
LIG_TRAF2_1	447	450	PF00917	0.439
LIG_TRAF2_1	558	561	PF00917	0.351
LIG_TYR_ITIM	56	61	PF00017	0.470
LIG_UBA3_1	318	325	PF00899	0.193
LIG_WRC_WIRS_1	100	105	PF05994	0.366
LIG_WRC_WIRS_1	564	569	PF05994	0.353
MOD_CDK_SPK_2	217	222	PF00069	0.439
MOD_CK1_1	570	576	PF00069	0.294
MOD_CK1_1	678	684	PF00069	0.323
MOD_CK1_1	727	733	PF00069	0.324
MOD_CK1_1	779	785	PF00069	0.720
MOD_CK2_1	241	247	PF00069	0.439
MOD_CK2_1	403	409	PF00069	0.309
MOD_CK2_1	444	450	PF00069	0.326
MOD_CK2_1	550	556	PF00069	0.520
MOD_CK2_1	593	599	PF00069	0.379
MOD_CK2_1	692	698	PF00069	0.439
MOD_CK2_1	786	792	PF00069	0.648
MOD_CK2_1	95	101	PF00069	0.388
MOD_Cter_Amidation	300	303	PF01082	0.294
MOD_GlcNHglycan	165	168	PF01048	0.195
MOD_GlcNHglycan	3	6	PF01048	0.556
MOD_GlcNHglycan	531	534	PF01048	0.439
MOD_GlcNHglycan	588	591	PF01048	0.309
MOD_GlcNHglycan	643	646	PF01048	0.294
MOD_GlcNHglycan	729	732	PF01048	0.419
MOD_GSK3_1	140	147	PF00069	0.366
MOD_GSK3_1	152	159	PF00069	0.289
MOD_GSK3_1	230	237	PF00069	0.512
MOD_GSK3_1	272	279	PF00069	0.326
MOD_GSK3_1	403	410	PF00069	0.312
MOD_GSK3_1	42	49	PF00069	0.426
MOD_GSK3_1	429	436	PF00069	0.303
MOD_GSK3_1	444	451	PF00069	0.269
MOD_GSK3_1	478	485	PF00069	0.329
MOD_GSK3_1	498	505	PF00069	0.230
MOD_GSK3_1	563	570	PF00069	0.353
MOD_GSK3_1	614	621	PF00069	0.286
MOD_GSK3_1	65	72	PF00069	0.328
MOD_GSK3_1	671	678	PF00069	0.439
MOD_GSK3_1	727	734	PF00069	0.310
MOD_GSK3_1	782	789	PF00069	0.596
MOD_GSK3_1	95	102	PF00069	0.376
MOD_N-GLC_1	275	280	PF02516	0.316
MOD_N-GLC_1	289	294	PF02516	0.254
MOD_N-GLC_1	46	51	PF02516	0.439
MOD_N-GLC_1	664	669	PF02516	0.334
MOD_N-GLC_1	675	680	PF02516	0.262
MOD_N-GLC_1	95	100	PF02516	0.494
MOD_N-GLC_2	364	366	PF02516	0.439
MOD_N-GLC_2	437	439	PF02516	0.294
MOD_N-GLC_2	627	629	PF02516	0.294
MOD_NEK2_1	1	6	PF00069	0.661
MOD_NEK2_1	156	161	PF00069	0.294
MOD_NEK2_1	289	294	PF00069	0.439
MOD_NEK2_1	476	481	PF00069	0.421
MOD_NEK2_1	606	611	PF00069	0.292
MOD_NEK2_1	692	697	PF00069	0.471
MOD_NEK2_1	86	91	PF00069	0.294
MOD_NEK2_1	99	104	PF00069	0.356
MOD_NEK2_2	563	568	PF00069	0.299
MOD_NEK2_2	664	669	PF00069	0.421
MOD_NEK2_2	87	92	PF00069	0.439
MOD_PIKK_1	403	409	PF00454	0.309
MOD_PIKK_1	618	624	PF00454	0.294
MOD_PIKK_1	715	721	PF00454	0.294
MOD_PIKK_1	776	782	PF00454	0.718
MOD_PIKK_1	786	792	PF00454	0.648
MOD_PK_1	234	240	PF00069	0.309
MOD_PKA_1	325	331	PF00069	0.294
MOD_PKA_1	786	792	PF00069	0.484
MOD_PKA_2	196	202	PF00069	0.439
MOD_PKA_2	325	331	PF00069	0.388
MOD_PKA_2	502	508	PF00069	0.309
MOD_PKA_2	606	612	PF00069	0.294
MOD_PKA_2	786	792	PF00069	0.648
MOD_Plk_1	144	150	PF00069	0.307
MOD_Plk_1	156	162	PF00069	0.289
MOD_Plk_1	234	240	PF00069	0.294
MOD_Plk_1	551	557	PF00069	0.356
MOD_Plk_1	664	670	PF00069	0.421
MOD_Plk_1	95	101	PF00069	0.440
MOD_Plk_2-3	593	599	PF00069	0.353
MOD_Plk_4	211	217	PF00069	0.314
MOD_Plk_4	267	273	PF00069	0.309
MOD_Plk_4	542	548	PF00069	0.294
MOD_Plk_4	606	612	PF00069	0.304
MOD_Plk_4	675	681	PF00069	0.460
MOD_Plk_4	732	738	PF00069	0.453
MOD_Plk_4	95	101	PF00069	0.369
MOD_ProDKin_1	209	215	PF00069	0.294
MOD_ProDKin_1	217	223	PF00069	0.294
MOD_ProDKin_1	444	450	PF00069	0.358
MOD_ProDKin_1	567	573	PF00069	0.294
MOD_ProDKin_1	724	730	PF00069	0.388
MOD_SUMO_for_1	352	355	PF00179	0.439
MOD_SUMO_for_1	558	561	PF00179	0.409
MOD_SUMO_rev_2	354	359	PF00179	0.395
TRG_AP2beta_CARGO_1	317	326	PF09066	0.388
TRG_DiLeu_BaEn_1	101	106	PF01217	0.507
TRG_DiLeu_BaEn_1	157	162	PF01217	0.294
TRG_DiLeu_BaEn_1	198	203	PF01217	0.353
TRG_DiLeu_BaEn_4	375	381	PF01217	0.365
TRG_DiLeu_BaLyEn_6	116	121	PF01217	0.386
TRG_DiLeu_LyEn_5	101	106	PF01217	0.507
TRG_ENDOCYTIC_2	153	156	PF00928	0.323
TRG_ENDOCYTIC_2	200	203	PF00928	0.294
TRG_ENDOCYTIC_2	242	245	PF00928	0.294
TRG_ENDOCYTIC_2	496	499	PF00928	0.337
TRG_ENDOCYTIC_2	564	567	PF00928	0.359
TRG_ENDOCYTIC_2	58	61	PF00928	0.440
TRG_ENDOCYTIC_2	653	656	PF00928	0.354
TRG_ENDOCYTIC_2	693	696	PF00928	0.294
TRG_ENDOCYTIC_2	79	82	PF00928	0.324
TRG_ER_diArg_1	23	26	PF00400	0.417
TRG_ER_diArg_1	349	351	PF00400	0.315
TRG_ER_diArg_1	507	510	PF00400	0.328
TRG_ER_diArg_1	639	641	PF00400	0.294
TRG_ER_FFAT_2	441	451	PF00635	0.358
TRG_Pf-PMV_PEXEL_1	104	108	PF00026	0.444
TRG_Pf-PMV_PEXEL_1	144	149	PF00026	0.490
TRG_Pf-PMV_PEXEL_1	50	54	PF00026	0.401
TRG_Pf-PMV_PEXEL_1	641	646	PF00026	0.294
TRG_Pf-PMV_PEXEL_1	661	666	PF00026	0.173
TRG_Pf-PMV_PEXEL_1	702	706	PF00026	0.319

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEL5	Leptomonas seymouri	88%	99%
A0A0S4IWY8	Bodo saltans	71%	100%
A0A1X0NYF0	Trypanosomatidae	72%	100%
A0A3S7X1E7	Leishmania donovani	98%	100%
A0A422N3W6	Trypanosoma rangeli	71%	100%
A4HGD3	Leishmania braziliensis	95%	100%
A4I3G6	Leishmania infantum	98%	100%
D0A7X4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	66%	95%
O15909	Trypanosoma brucei brucei	66%	95%
O36411	Alcelaphine herpesvirus 1 (strain C500)	26%	100%
O54196	Streptomyces clavuligerus	23%	83%
O61065	Cryptosporidium parvum	54%	100%
O66503	Aquifex aeolicus (strain VF5)	32%	100%
O69981	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	22%	83%
O83972	Treponema pallidum (strain Nichols)	33%	95%
O84834	Chlamydia trachomatis (strain D/UW-3/Cx)	36%	76%
P00452	Escherichia coli (strain K12)	27%	100%
P03190	Epstein-Barr virus (strain B95-8)	27%	97%
P07742	Mus musculus	57%	100%
P08543	Human herpesvirus 1 (strain 17)	31%	70%
P09248	Varicella-zoster virus (strain Dumas)	29%	100%
P09853	Human herpesvirus 2 (strain 333)	32%	70%
P0A5W9	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	28%	100%
P0C702	Epstein-Barr virus (strain AG876)	27%	97%
P0C8H7	African swine fever virus (isolate Pig/Kenya/KEN-50/1950)	39%	100%
P0C8H8	African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996)	38%	100%
P0C8H9	African swine fever virus (isolate Warthog/Namibia/Wart80/1980)	38%	100%
P0CG99	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	28%	100%
P0CH00	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	28%	100%
P0DSV1	Variola virus (isolate Human/India/Ind3/1967)	56%	100%
P0DSV2	Variola virus	56%	100%
P12848	Vaccinia virus (strain Western Reserve)	56%	100%
P20503	Vaccinia virus (strain Copenhagen)	56%	100%
P21524	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	60%	90%
P21672	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	60%	92%
P23921	Homo sapiens	57%	100%
P26685	African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983)	38%	100%
P28846	Equine herpesvirus 1 (strain Ab4p)	31%	100%
P32282	Enterobacteria phage T4	27%	100%
P36602	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	60%	99%
P37426	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	27%	100%
P39452	Escherichia coli (strain K12)	27%	100%
P42491	African swine fever virus (strain Badajoz 1971 Vero-adapted)	38%	100%
P43754	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	27%	100%
P47473	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	26%	100%
P48591	Drosophila melanogaster	54%	98%
P50620	Bacillus subtilis (strain 168)	25%	100%
P50642	Equine herpesvirus 4 (strain 1942)	31%	100%
P50643	Suid herpesvirus 1 (strain Kaplan)	30%	96%
P50646	Bovine herpesvirus 1.1 (strain Cooper)	31%	100%
P50647	Plasmodium falciparum (isolate FCR-3 / Gambia)	58%	99%
P50648	Plasmodium falciparum (isolate Dd2)	59%	99%
P55982	Helicobacter pylori (strain ATCC 700392 / 26695)	31%	100%
P57276	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	27%	100%
P74240	Synechocystis sp. (strain PCC 6803 / Kazusa)	28%	100%
P78027	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	25%	100%
P79732	Danio rerio	59%	100%
P89462	Human herpesvirus 2 (strain HG52)	31%	70%
P9WH74	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	28%	100%
P9WH75	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	28%	100%
P9WH76	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	26%	100%
P9WH77	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	26%	100%
Q01037	Saimiriine herpesvirus 2 (strain 11)	28%	100%
Q03604	Caenorhabditis elegans	58%	100%
Q08698	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	28%	100%
Q196Z5	Invertebrate iridescent virus 3	28%	100%
Q2HR67	Human herpesvirus 8 type P (isolate GK18)	28%	100%
Q3KSU5	Epstein-Barr virus (strain GD1)	27%	97%
Q4JQV6	Varicella-zoster virus (strain Oka vaccine)	29%	100%
Q4Q8H8	Leishmania major	97%	100%
Q54Q71	Dictyostelium discoideum	61%	92%
Q5R919	Pongo abelii	57%	100%
Q66663	Equine herpesvirus 2 (strain 86/87)	26%	100%
Q6GZT8	Frog virus 3 (isolate Goorha)	29%	100%
Q6MNP6	Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)	24%	100%
Q6R7H4	Ostreid herpesvirus 1 (isolate France)	32%	96%
Q6UDJ2	Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997)	29%	99%
Q76RD8	Vaccinia virus (strain Ankara)	56%	100%
Q77MS1	Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)	33%	97%
Q7T6Y8	Acanthamoeba polyphaga mimivirus	48%	91%
Q7UI46	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	24%	77%
Q82KE2	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	22%	83%
Q89AS4	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	26%	100%
Q8K9W3	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	27%	100%
Q8SR37	Encephalitozoon cuniculi (strain GB-M1)	50%	100%
Q9CBQ0	Mycobacterium leprae (strain TN)	27%	100%
Q9PL93	Chlamydia muridarum (strain MoPn / Nigg)	36%	76%
Q9SJ20	Arabidopsis thaliana	58%	98%
Q9UW15	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	59%	86%
Q9Z6S5	Chlamydia pneumoniae	36%	77%
Q9ZLF9	Helicobacter pylori (strain J99 / ATCC 700824)	31%	100%
V5DH46	Trypanosoma cruzi	72%	100%