DNA replication licensing factor MCM2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

minichromosome maintenance (MCM) complex subunit, putative

Species:

Leishmania mexicana

UniProt:

E9AZQ1_LEIMU

TriTrypDb:

LmxM.28.0850

Length:

971

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	12
GO:0032991	protein-containing complex	1	12
GO:0042555	MCM complex	2	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12

Expansion

Sequence features

E9AZQ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZQ1

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006268	DNA unwinding involved in DNA replication	9	12
GO:0006270	DNA replication initiation	5	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006996	organelle organization	4	12
GO:0007049	cell cycle	2	11
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0010639	negative regulation of organelle organization	6	12
GO:0016043	cellular component organization	3	12
GO:0032392	DNA geometric change	7	12
GO:0032508	DNA duplex unwinding	8	12
GO:0032780	negative regulation of ATP-dependent activity	4	12
GO:0033043	regulation of organelle organization	5	12
GO:0033044	regulation of chromosome organization	6	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043086	negative regulation of catalytic activity	4	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043462	regulation of ATP-dependent activity	3	12
GO:0044092	negative regulation of molecular function	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0048519	negative regulation of biological process	3	12
GO:0048523	negative regulation of cellular process	4	12
GO:0050789	regulation of biological process	2	12
GO:0050790	regulation of catalytic activity	3	12
GO:0050794	regulation of cellular process	3	12
GO:0051095	regulation of helicase activity	4	12
GO:0051097	negative regulation of helicase activity	5	12
GO:0051128	regulation of cellular component organization	4	12
GO:0051129	negative regulation of cellular component organization	5	12
GO:0051276	chromosome organization	5	12
GO:0065007	biological regulation	1	12
GO:0065009	regulation of molecular function	2	12
GO:0071103	DNA conformation change	6	12
GO:0071704	organic substance metabolic process	2	12
GO:0071840	cellular component organization or biogenesis	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1905462	regulation of DNA duplex unwinding	7	12
GO:1905463	negative regulation of DNA duplex unwinding	8	12
GO:1905774	regulation of DNA helicase activity	5	12
GO:1905775	negative regulation of DNA helicase activity	6	12
GO:2001251	negative regulation of chromosome organization	7	12
GO:0000724	double-strand break repair via homologous recombination	7	1
GO:0000725	recombinational repair	6	1
GO:0000727	double-strand break repair via break-induced replication	8	1
GO:0006281	DNA repair	5	1
GO:0006302	double-strand break repair	6	1
GO:0006310	DNA recombination	5	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0022402	cell cycle process	2	1
GO:0033554	cellular response to stress	3	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:1902292	cell cycle DNA replication initiation	3	1
GO:1902315	nuclear cell cycle DNA replication initiation	4	1
GO:1902975	mitotic DNA replication initiation	4	1
GO:1903047	mitotic cell cycle process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003678	DNA helicase activity	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0016887	ATP hydrolysis activity	7	12
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0043169	cation binding	3	12
GO:0046872	metal ion binding	4	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0003697	single-stranded DNA binding	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	20	24	PF00656	0.768
CLV_C14_Caspase3-7	769	773	PF00656	0.520
CLV_NRD_NRD_1	11	13	PF00675	0.618
CLV_NRD_NRD_1	112	114	PF00675	0.221
CLV_NRD_NRD_1	123	125	PF00675	0.183
CLV_NRD_NRD_1	15	17	PF00675	0.615
CLV_NRD_NRD_1	215	217	PF00675	0.347
CLV_NRD_NRD_1	297	299	PF00675	0.230
CLV_NRD_NRD_1	31	33	PF00675	0.583
CLV_NRD_NRD_1	337	339	PF00675	0.202
CLV_NRD_NRD_1	469	471	PF00675	0.368
CLV_NRD_NRD_1	497	499	PF00675	0.206
CLV_NRD_NRD_1	754	756	PF00675	0.522
CLV_NRD_NRD_1	782	784	PF00675	0.213
CLV_NRD_NRD_1	879	881	PF00675	0.359
CLV_NRD_NRD_1	948	950	PF00675	0.510
CLV_PCSK_FUR_1	11	15	PF00082	0.604
CLV_PCSK_KEX2_1	11	13	PF00082	0.587
CLV_PCSK_KEX2_1	111	113	PF00082	0.218
CLV_PCSK_KEX2_1	123	125	PF00082	0.163
CLV_PCSK_KEX2_1	14	16	PF00082	0.583
CLV_PCSK_KEX2_1	215	217	PF00082	0.347
CLV_PCSK_KEX2_1	31	33	PF00082	0.670
CLV_PCSK_KEX2_1	337	339	PF00082	0.202
CLV_PCSK_KEX2_1	469	471	PF00082	0.378
CLV_PCSK_KEX2_1	497	499	PF00082	0.159
CLV_PCSK_KEX2_1	754	756	PF00082	0.522
CLV_PCSK_PC1ET2_1	13	15	PF00082	0.586
CLV_PCSK_PC7_1	7	13	PF00082	0.573
CLV_PCSK_SKI1_1	216	220	PF00082	0.318
CLV_PCSK_SKI1_1	498	502	PF00082	0.221
CLV_PCSK_SKI1_1	567	571	PF00082	0.202
CLV_PCSK_SKI1_1	699	703	PF00082	0.210
CLV_PCSK_SKI1_1	734	738	PF00082	0.426
CLV_PCSK_SKI1_1	784	788	PF00082	0.213
CLV_PCSK_SKI1_1	880	884	PF00082	0.514
CLV_Separin_Metazoa	212	216	PF03568	0.334
DEG_APCC_DBOX_1	187	195	PF00400	0.536
DEG_APCC_DBOX_1	497	505	PF00400	0.370
DEG_APCC_DBOX_1	680	688	PF00400	0.412
DEG_ODPH_VHL_1	504	516	PF01847	0.413
DEG_SCF_FBW7_1	674	680	PF00400	0.402
DOC_CKS1_1	674	679	PF01111	0.409
DOC_CYCLIN_RxL_1	492	503	PF00134	0.434
DOC_MAPK_gen_1	298	306	PF00069	0.413
DOC_MAPK_gen_1	318	327	PF00069	0.316
DOC_MAPK_gen_1	365	374	PF00069	0.384
DOC_MAPK_gen_1	412	421	PF00069	0.402
DOC_MAPK_gen_1	428	437	PF00069	0.402
DOC_MAPK_gen_1	537	544	PF00069	0.402
DOC_MAPK_gen_1	894	901	PF00069	0.473
DOC_MAPK_HePTP_8	508	520	PF00069	0.402
DOC_MAPK_MEF2A_6	299	308	PF00069	0.450
DOC_MAPK_MEF2A_6	321	329	PF00069	0.402
DOC_MAPK_MEF2A_6	412	421	PF00069	0.402
DOC_MAPK_MEF2A_6	511	520	PF00069	0.402
DOC_MAPK_MEF2A_6	537	546	PF00069	0.402
DOC_MAPK_MEF2A_6	689	696	PF00069	0.413
DOC_MAPK_MEF2A_6	817	825	PF00069	0.402
DOC_MAPK_MEF2A_6	894	901	PF00069	0.486
DOC_MAPK_NFAT4_5	511	519	PF00069	0.406
DOC_MAPK_RevD_3	325	338	PF00069	0.402
DOC_PP1_RVXF_1	782	789	PF00149	0.453
DOC_PP4_FxxP_1	477	480	PF00568	0.405
DOC_USP7_MATH_1	353	357	PF00917	0.417
DOC_USP7_MATH_1	41	45	PF00917	0.417
DOC_USP7_MATH_1	664	668	PF00917	0.445
DOC_USP7_MATH_1	854	858	PF00917	0.448
DOC_USP7_MATH_1	932	936	PF00917	0.529
DOC_USP7_UBL2_3	559	563	PF12436	0.402
DOC_WW_Pin1_4	336	341	PF00397	0.402
DOC_WW_Pin1_4	490	495	PF00397	0.506
DOC_WW_Pin1_4	673	678	PF00397	0.409
LIG_14-3-3_CanoR_1	354	358	PF00244	0.424
LIG_14-3-3_CanoR_1	371	375	PF00244	0.373
LIG_14-3-3_CanoR_1	412	418	PF00244	0.423
LIG_14-3-3_CanoR_1	469	477	PF00244	0.429
LIG_14-3-3_CanoR_1	574	581	PF00244	0.402
LIG_14-3-3_CanoR_1	699	704	PF00244	0.493
LIG_14-3-3_CanoR_1	833	841	PF00244	0.426
LIG_Actin_WH2_2	857	874	PF00022	0.471
LIG_APCC_ABBA_1	234	239	PF00400	0.506
LIG_BIR_III_4	151	155	PF00653	0.454
LIG_BIR_III_4	23	27	PF00653	0.588
LIG_BRCT_BRCA1_1	301	305	PF00533	0.506
LIG_BRCT_BRCA1_1	664	668	PF00533	0.413
LIG_BRCT_BRCA1_1	762	766	PF00533	0.508
LIG_BRCT_BRCA1_1	790	794	PF00533	0.506
LIG_BRCT_BRCA1_1	944	948	PF00533	0.363
LIG_BRCT_BRCA1_2	944	950	PF00533	0.360
LIG_Clathr_ClatBox_1	328	332	PF01394	0.402
LIG_FHA_1	288	294	PF00498	0.506
LIG_FHA_1	396	402	PF00498	0.431
LIG_FHA_1	420	426	PF00498	0.431
LIG_FHA_1	457	463	PF00498	0.332
LIG_FHA_1	469	475	PF00498	0.416
LIG_FHA_1	580	586	PF00498	0.402
LIG_FHA_1	631	637	PF00498	0.410
LIG_FHA_1	673	679	PF00498	0.402
LIG_FHA_1	717	723	PF00498	0.586
LIG_FHA_1	851	857	PF00498	0.506
LIG_FHA_1	885	891	PF00498	0.429
LIG_FHA_2	664	670	PF00498	0.506
LIG_FHA_2	713	719	PF00498	0.473
LIG_FHA_2	740	746	PF00498	0.486
LIG_FHA_2	846	852	PF00498	0.506
LIG_GBD_Chelix_1	205	213	PF00786	0.364
LIG_Integrin_RGD_1	188	190	PF01839	0.542
LIG_Integrin_RGD_1	539	541	PF01839	0.202
LIG_LIR_Apic_2	175	181	PF02991	0.683
LIG_LIR_Apic_2	65	69	PF02991	0.431
LIG_LIR_Gen_1	128	138	PF02991	0.444
LIG_LIR_Gen_1	255	263	PF02991	0.406
LIG_LIR_Gen_1	302	313	PF02991	0.551
LIG_LIR_Gen_1	555	565	PF02991	0.402
LIG_LIR_Gen_1	612	621	PF02991	0.402
LIG_LIR_Gen_1	680	688	PF02991	0.402
LIG_LIR_Nem_3	128	134	PF02991	0.444
LIG_LIR_Nem_3	255	259	PF02991	0.404
LIG_LIR_Nem_3	260	266	PF02991	0.405
LIG_LIR_Nem_3	290	294	PF02991	0.506
LIG_LIR_Nem_3	302	308	PF02991	0.478
LIG_LIR_Nem_3	319	323	PF02991	0.337
LIG_LIR_Nem_3	555	560	PF02991	0.402
LIG_LIR_Nem_3	680	685	PF02991	0.402
LIG_LIR_Nem_3	791	797	PF02991	0.495
LIG_LIR_Nem_3	876	882	PF02991	0.371
LIG_LIR_Nem_3	951	955	PF02991	0.397
LIG_LYPXL_S_1	341	345	PF13949	0.202
LIG_LYPXL_yS_3	342	345	PF13949	0.402
LIG_NRBOX	515	521	PF00104	0.413
LIG_PCNA_PIPBox_1	936	945	PF02747	0.512
LIG_PCNA_yPIPBox_3	199	209	PF02747	0.369
LIG_PCNA_yPIPBox_3	775	786	PF02747	0.338
LIG_PCNA_yPIPBox_3	936	950	PF02747	0.515
LIG_PDZ_Class_1	966	971	PF00595	0.403
LIG_Pex14_2	682	686	PF04695	0.402
LIG_Pex14_2	859	863	PF04695	0.402
LIG_PTB_Apo_2	217	224	PF02174	0.252
LIG_PTB_Phospho_1	217	223	PF10480	0.252
LIG_SH2_CRK	227	231	PF00017	0.417
LIG_SH2_CRK	263	267	PF00017	0.402
LIG_SH2_CRK	297	301	PF00017	0.406
LIG_SH2_CRK	952	956	PF00017	0.357
LIG_SH2_GRB2like	226	229	PF00017	0.413
LIG_SH2_PTP2	809	812	PF00017	0.506
LIG_SH2_SRC	357	360	PF00017	0.426
LIG_SH2_SRC	662	665	PF00017	0.413
LIG_SH2_STAP1	237	241	PF00017	0.402
LIG_SH2_STAP1	263	267	PF00017	0.413
LIG_SH2_STAP1	930	934	PF00017	0.529
LIG_SH2_STAT5	186	189	PF00017	0.506
LIG_SH2_STAT5	229	232	PF00017	0.420
LIG_SH2_STAT5	288	291	PF00017	0.402
LIG_SH2_STAT5	357	360	PF00017	0.443
LIG_SH2_STAT5	66	69	PF00017	0.413
LIG_SH2_STAT5	785	788	PF00017	0.402
LIG_SH2_STAT5	809	812	PF00017	0.413
LIG_SH2_STAT5	846	849	PF00017	0.466
LIG_SH2_STAT5	930	933	PF00017	0.535
LIG_SH3_1	337	343	PF00018	0.402
LIG_SH3_2	27	32	PF14604	0.700
LIG_SH3_3	24	30	PF00018	0.698
LIG_SH3_3	269	275	PF00018	0.413
LIG_SH3_3	337	343	PF00018	0.402
LIG_SH3_3	544	550	PF00018	0.430
LIG_SH3_4	775	782	PF00018	0.364
LIG_SUMO_SIM_anti_2	416	422	PF11976	0.435
LIG_SUMO_SIM_par_1	276	284	PF11976	0.415
LIG_SUMO_SIM_par_1	397	403	PF11976	0.413
LIG_SUMO_SIM_par_1	486	491	PF11976	0.471
LIG_SUMO_SIM_par_1	543	549	PF11976	0.402
LIG_TRAF2_1	431	434	PF00917	0.413
LIG_TRAF2_1	50	53	PF00917	0.464
LIG_TRAF2_1	69	72	PF00917	0.462
LIG_TRAF2_1	715	718	PF00917	0.441
LIG_TRFH_1	291	295	PF08558	0.224
LIG_TYR_ITIM	254	259	PF00017	0.237
LIG_UBA3_1	487	492	PF00899	0.252
LIG_UBA3_1	519	528	PF00899	0.237
LIG_WRC_WIRS_1	288	293	PF05994	0.382
LIG_WRC_WIRS_1	700	705	PF05994	0.216
LIG_WW_3	28	32	PF00397	0.724
MOD_CDK_SPxxK_3	490	497	PF00069	0.382
MOD_CK1_1	145	151	PF00069	0.725
MOD_CK1_1	377	383	PF00069	0.252
MOD_CK1_1	870	876	PF00069	0.346
MOD_CK1_1	92	98	PF00069	0.252
MOD_CK2_1	232	238	PF00069	0.271
MOD_CK2_1	363	369	PF00069	0.137
MOD_CK2_1	42	48	PF00069	0.333
MOD_CK2_1	621	627	PF00069	0.237
MOD_CK2_1	712	718	PF00069	0.430
MOD_CK2_1	739	745	PF00069	0.521
MOD_CK2_1	761	767	PF00069	0.584
MOD_CK2_1	870	876	PF00069	0.346
MOD_CK2_1	882	888	PF00069	0.399
MOD_CK2_1	90	96	PF00069	0.382
MOD_GlcNHglycan	147	150	PF01048	0.595
MOD_GlcNHglycan	157	160	PF01048	0.587
MOD_GlcNHglycan	44	47	PF01048	0.385
MOD_GlcNHglycan	645	648	PF01048	0.252
MOD_GlcNHglycan	872	875	PF01048	0.361
MOD_GlcNHglycan	911	914	PF01048	0.414
MOD_GSK3_1	248	255	PF00069	0.237
MOD_GSK3_1	370	377	PF00069	0.273
MOD_GSK3_1	500	507	PF00069	0.237
MOD_GSK3_1	561	568	PF00069	0.271
MOD_GSK3_1	569	576	PF00069	0.205
MOD_GSK3_1	673	680	PF00069	0.237
MOD_GSK3_1	712	719	PF00069	0.477
MOD_GSK3_1	756	763	PF00069	0.584
MOD_GSK3_1	850	857	PF00069	0.294
MOD_GSK3_1	863	870	PF00069	0.263
MOD_GSK3_1	882	889	PF00069	0.399
MOD_GSK3_1	928	935	PF00069	0.401
MOD_N-GLC_1	672	677	PF02516	0.235
MOD_N-GLC_1	738	743	PF02516	0.441
MOD_N-GLC_1	932	937	PF02516	0.421
MOD_NEK2_1	155	160	PF00069	0.568
MOD_NEK2_1	448	453	PF00069	0.384
MOD_NEK2_1	500	505	PF00069	0.245
MOD_NEK2_1	581	586	PF00069	0.237
MOD_NEK2_1	788	793	PF00069	0.382
MOD_NEK2_1	863	868	PF00069	0.299
MOD_NEK2_2	565	570	PF00069	0.382
MOD_NEK2_2	854	859	PF00069	0.252
MOD_NEK2_2	900	905	PF00069	0.362
MOD_PIKK_1	552	558	PF00454	0.237
MOD_PIKK_1	712	718	PF00454	0.408
MOD_PIKK_1	863	869	PF00454	0.310
MOD_PIKK_1	915	921	PF00454	0.463
MOD_PIKK_1	932	938	PF00454	0.378
MOD_PKA_1	469	475	PF00069	0.509
MOD_PKA_2	1	7	PF00069	0.751
MOD_PKA_2	353	359	PF00069	0.277
MOD_PKA_2	370	376	PF00069	0.341
MOD_PKA_2	388	394	PF00069	0.301
MOD_PKA_2	468	474	PF00069	0.392
MOD_PKA_2	573	579	PF00069	0.237
MOD_PKA_2	621	627	PF00069	0.263
MOD_PKA_2	756	762	PF00069	0.471
MOD_PKA_2	795	801	PF00069	0.237
MOD_PKA_2	832	838	PF00069	0.271
MOD_Plk_1	142	148	PF00069	0.746
MOD_Plk_1	232	238	PF00069	0.339
MOD_Plk_1	248	254	PF00069	0.155
MOD_Plk_1	565	571	PF00069	0.382
MOD_Plk_1	620	626	PF00069	0.252
MOD_Plk_1	716	722	PF00069	0.627
MOD_Plk_1	728	734	PF00069	0.450
MOD_Plk_1	761	767	PF00069	0.619
MOD_Plk_1	89	95	PF00069	0.281
MOD_Plk_2-3	47	53	PF00069	0.186
MOD_Plk_2-3	615	621	PF00069	0.237
MOD_Plk_2-3	845	851	PF00069	0.382
MOD_Plk_2-3	90	96	PF00069	0.382
MOD_Plk_4	142	148	PF00069	0.586
MOD_Plk_4	232	238	PF00069	0.271
MOD_Plk_4	262	268	PF00069	0.240
MOD_Plk_4	353	359	PF00069	0.277
MOD_Plk_4	395	401	PF00069	0.252
MOD_Plk_4	457	463	PF00069	0.332
MOD_Plk_4	699	705	PF00069	0.216
MOD_Plk_4	827	833	PF00069	0.237
MOD_Plk_4	854	860	PF00069	0.301
MOD_ProDKin_1	336	342	PF00069	0.237
MOD_ProDKin_1	490	496	PF00069	0.382
MOD_ProDKin_1	673	679	PF00069	0.246
MOD_SUMO_rev_2	233	241	PF00179	0.277
MOD_SUMO_rev_2	507	516	PF00179	0.237
TRG_DiLeu_BaEn_1	597	602	PF01217	0.237
TRG_DiLeu_BaEn_1	717	722	PF01217	0.505
TRG_DiLeu_BaEn_4	52	58	PF01217	0.379
TRG_DiLeu_BaEn_4	717	723	PF01217	0.586
TRG_DiLeu_BaEn_4	728	734	PF01217	0.533
TRG_DiLeu_BaLyEn_6	444	449	PF01217	0.372
TRG_DiLeu_BaLyEn_6	950	955	PF01217	0.509
TRG_DiLeu_LyEn_5	717	722	PF01217	0.505
TRG_DiLeu_LyEn_5	888	893	PF01217	0.392
TRG_ENDOCYTIC_2	227	230	PF00928	0.258
TRG_ENDOCYTIC_2	256	259	PF00928	0.237
TRG_ENDOCYTIC_2	263	266	PF00928	0.237
TRG_ENDOCYTIC_2	288	291	PF00928	0.239
TRG_ENDOCYTIC_2	297	300	PF00928	0.233
TRG_ENDOCYTIC_2	342	345	PF00928	0.237
TRG_ENDOCYTIC_2	785	788	PF00928	0.331
TRG_ENDOCYTIC_2	809	812	PF00928	0.237
TRG_ENDOCYTIC_2	952	955	PF00928	0.401
TRG_ER_diArg_1	10	12	PF00400	0.615
TRG_ER_diArg_1	111	113	PF00400	0.344
TRG_ER_diArg_1	14	16	PF00400	0.622
TRG_ER_diArg_1	214	216	PF00400	0.343
TRG_ER_diArg_1	30	32	PF00400	0.504
TRG_ER_diArg_1	336	338	PF00400	0.237
TRG_ER_diArg_1	468	470	PF00400	0.359
TRG_ER_diArg_1	484	487	PF00400	0.202
TRG_ER_diArg_1	496	498	PF00400	0.235
TRG_ER_diArg_1	732	735	PF00400	0.491
TRG_ER_diArg_1	753	755	PF00400	0.476
TRG_ER_diArg_1	893	896	PF00400	0.508
TRG_ER_FFAT_2	923	935	PF00635	0.447
TRG_NES_CRM1_1	683	698	PF08389	0.252
TRG_NLS_MonoCore_2	11	16	PF00514	0.664
TRG_NLS_MonoExtC_3	11	16	PF00514	0.664
TRG_NLS_MonoExtN_4	11	17	PF00514	0.686
TRG_Pf-PMV_PEXEL_1	124	128	PF00026	0.317
TRG_Pf-PMV_PEXEL_1	498	502	PF00026	0.382
TRG_Pf-PMV_PEXEL_1	720	725	PF00026	0.456
TRG_Pf-PMV_PEXEL_1	754	758	PF00026	0.532
TRG_Pf-PMV_PEXEL_1	953	957	PF00026	0.508

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P860	Leptomonas seymouri	87%	98%
A0A0N1I383	Leptomonas seymouri	32%	95%
A0A0S4IK09	Bodo saltans	63%	98%
A0A1X0NZT6	Trypanosomatidae	75%	100%
A0A3Q8IAX4	Leishmania donovani	97%	100%
A0A3R7K9K0	Trypanosoma rangeli	31%	100%
A0A3R7NBN0	Trypanosoma rangeli	76%	100%
A0A3S7WQI8	Leishmania donovani	29%	100%
A0A3S7WY81	Leishmania donovani	29%	100%
A0A3S7X726	Leishmania donovani	33%	100%
A4FUD9	Bos taurus	33%	100%
A4H5K0	Leishmania braziliensis	31%	100%
A4HDE7	Leishmania braziliensis	30%	100%
A4HGC9	Leishmania braziliensis	92%	100%
A4HLY1	Leishmania braziliensis	32%	100%
A4HNF5	Leishmania braziliensis	29%	100%
A4HTX2	Leishmania infantum	29%	100%
A4I0T0	Leishmania infantum	29%	100%
A4I3G2	Leishmania infantum	97%	100%
A4I9B0	Leishmania infantum	33%	100%
B8AZ99	Oryza sativa subsp. indica	34%	100%
B8BKI8	Oryza sativa subsp. indica	42%	100%
D0A7X6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	100%
E9AMM4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AWT2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B4B0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
F1M5F3	Rattus norvegicus	32%	86%
F1N2W9	Bos taurus	31%	85%
P25205	Homo sapiens	34%	100%
P29469	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	47%	100%
P30666	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
P40377	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	43%	100%
P41389	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
P49735	Drosophila melanogaster	44%	100%
P49736	Homo sapiens	45%	100%
P55861	Xenopus laevis	40%	100%
P97310	Mus musculus	44%	100%
Q0DHC4	Oryza sativa subsp. japonica	34%	100%
Q21902	Caenorhabditis elegans	29%	100%
Q29JI9	Drosophila pseudoobscura pseudoobscura	31%	100%
Q2KHI9	Mus musculus	32%	86%
Q2R482	Oryza sativa subsp. japonica	42%	100%
Q43704	Zea mays	35%	100%
Q4Q3R6	Leishmania major	32%	100%
Q4Q8I2	Leishmania major	97%	100%
Q4QAP2	Leishmania major	31%	100%
Q4QI01	Leishmania major	29%	100%
Q54CP4	Dictyostelium discoideum	31%	100%
Q5R8G6	Pongo abelii	34%	100%
Q6DIH3	Xenopus tropicalis	42%	100%
Q6NRM6	Xenopus laevis	30%	85%
Q9LPD9	Arabidopsis thaliana	45%	100%
Q9NXL9	Homo sapiens	31%	85%
Q9SF37	Arabidopsis thaliana	32%	100%
Q9SX03	Zea mays	35%	100%
Q9SX04	Zea mays	35%	100%
Q9V461	Drosophila melanogaster	32%	100%
Q9VGW6	Drosophila melanogaster	32%	100%
Q9XYU0	Drosophila melanogaster	33%	100%
V5BQA9	Trypanosoma cruzi	80%	100%
V5BSG2	Trypanosoma cruzi	30%	100%