Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AZP0_LEIMU

TriTrypDb:

LmxM.28.0785

Length:

190

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZP0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZP0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	147	153	PF00089	0.447
CLV_NRD_NRD_1	129	131	PF00675	0.509
CLV_NRD_NRD_1	174	176	PF00675	0.553
CLV_NRD_NRD_1	27	29	PF00675	0.534
CLV_PCSK_KEX2_1	128	130	PF00082	0.444
CLV_PCSK_KEX2_1	176	178	PF00082	0.467
CLV_PCSK_KEX2_1	27	29	PF00082	0.534
CLV_PCSK_KEX2_1	88	90	PF00082	0.696
CLV_PCSK_PC1ET2_1	176	178	PF00082	0.467
CLV_PCSK_PC1ET2_1	88	90	PF00082	0.696
CLV_PCSK_SKI1_1	122	126	PF00082	0.498
CLV_PCSK_SKI1_1	130	134	PF00082	0.434
DEG_APCC_DBOX_1	174	182	PF00400	0.534
DEG_APCC_KENBOX_2	106	110	PF00400	0.535
DOC_CKS1_1	90	95	PF01111	0.432
DOC_MAPK_gen_1	128	136	PF00069	0.328
DOC_MAPK_MEF2A_6	56	63	PF00069	0.602
DOC_PP1_RVXF_1	120	127	PF00149	0.536
DOC_PP4_FxxP_1	90	93	PF00568	0.464
DOC_USP7_MATH_1	73	77	PF00917	0.578
DOC_USP7_MATH_1	98	102	PF00917	0.509
DOC_WW_Pin1_4	54	59	PF00397	0.619
DOC_WW_Pin1_4	89	94	PF00397	0.469
LIG_14-3-3_CanoR_1	128	133	PF00244	0.470
LIG_14-3-3_CanoR_1	150	156	PF00244	0.479
LIG_14-3-3_CanoR_1	161	168	PF00244	0.520
LIG_14-3-3_CanoR_1	185	189	PF00244	0.479
LIG_14-3-3_CanoR_1	89	93	PF00244	0.690
LIG_BIR_II_1	1	5	PF00653	0.638
LIG_BRCT_BRCA1_1	14	18	PF00533	0.484
LIG_Clathr_ClatBox_1	136	140	PF01394	0.489
LIG_DLG_GKlike_1	128	136	PF00625	0.466
LIG_FHA_1	151	157	PF00498	0.460
LIG_FHA_2	136	142	PF00498	0.465
LIG_FHA_2	167	173	PF00498	0.440
LIG_FHA_2	18	24	PF00498	0.551
LIG_FHA_2	34	40	PF00498	0.658
LIG_FHA_2	76	82	PF00498	0.613
LIG_FHA_2	8	14	PF00498	0.635
LIG_LIR_Gen_1	101	110	PF02991	0.357
LIG_LIR_Gen_1	131	139	PF02991	0.471
LIG_LIR_Nem_3	101	106	PF02991	0.348
LIG_LIR_Nem_3	131	136	PF02991	0.584
LIG_PDZ_Class_2	185	190	PF00595	0.447
LIG_Pex14_2	133	137	PF04695	0.466
LIG_SH2_STAT5	30	33	PF00017	0.629
LIG_SH2_STAT5	34	37	PF00017	0.679
LIG_SH3_3	110	116	PF00018	0.582
LIG_SH3_3	41	47	PF00018	0.599
LIG_TRAF2_1	10	13	PF00917	0.567
LIG_TRAF2_1	138	141	PF00917	0.512
MOD_CK1_1	135	141	PF00069	0.531
MOD_CK1_1	164	170	PF00069	0.538
MOD_CK1_1	7	13	PF00069	0.585
MOD_CK1_1	82	88	PF00069	0.614
MOD_CK2_1	135	141	PF00069	0.531
MOD_CK2_1	166	172	PF00069	0.584
MOD_CK2_1	7	13	PF00069	0.576
MOD_CK2_1	75	81	PF00069	0.582
MOD_GlcNHglycan	161	164	PF01048	0.602
MOD_GlcNHglycan	80	84	PF01048	0.595
MOD_GSK3_1	128	135	PF00069	0.519
MOD_GSK3_1	164	171	PF00069	0.640
MOD_GSK3_1	3	10	PF00069	0.574
MOD_GSK3_1	75	82	PF00069	0.655
MOD_NEK2_1	132	137	PF00069	0.432
MOD_NEK2_1	17	22	PF00069	0.534
MOD_NEK2_1	4	9	PF00069	0.604
MOD_NEK2_2	98	103	PF00069	0.338
MOD_PIKK_1	8	14	PF00454	0.635
MOD_PKA_1	128	134	PF00069	0.468
MOD_PKA_1	88	94	PF00069	0.637
MOD_PKA_2	128	134	PF00069	0.468
MOD_PKA_2	149	155	PF00069	0.502
MOD_PKA_2	184	190	PF00069	0.437
MOD_PKA_2	88	94	PF00069	0.577
MOD_Plk_1	164	170	PF00069	0.605
MOD_Plk_1	73	79	PF00069	0.737
MOD_Plk_4	132	138	PF00069	0.472
MOD_Plk_4	98	104	PF00069	0.622
MOD_ProDKin_1	54	60	PF00069	0.619
MOD_ProDKin_1	89	95	PF00069	0.459
TRG_ER_diArg_1	128	130	PF00400	0.517
TRG_ER_diArg_1	174	177	PF00400	0.551
TRG_NES_CRM1_1	104	118	PF08389	0.560
TRG_NLS_MonoExtN_4	173	179	PF00514	0.372

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7T0	Leptomonas seymouri	45%	95%
A0A3S7X1A2	Leishmania donovani	84%	100%
A4HGB9	Leishmania braziliensis	74%	100%
E9ADJ8	Leishmania major	87%	100%
E9AHH7	Leishmania infantum	85%	100%