LeishMANIAdb
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ANK_REP_REGION domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
ANK_REP_REGION domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AZN9_LEIMU
TriTrypDb:
LmxM.28.0770
Length:
479

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZN9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZN9

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 227 229 PF00675 0.629
CLV_NRD_NRD_1 367 369 PF00675 0.805
CLV_NRD_NRD_1 45 47 PF00675 0.379
CLV_NRD_NRD_1 89 91 PF00675 0.611
CLV_PCSK_KEX2_1 167 169 PF00082 0.731
CLV_PCSK_KEX2_1 367 369 PF00082 0.805
CLV_PCSK_KEX2_1 463 465 PF00082 0.689
CLV_PCSK_PC1ET2_1 167 169 PF00082 0.731
CLV_PCSK_PC1ET2_1 463 465 PF00082 0.734
CLV_PCSK_SKI1_1 112 116 PF00082 0.512
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PES7 Leptomonas seymouri 38% 100%
A0A3Q8ID12 Leishmania donovani 88% 100%
A4HGB8 Leishmania braziliensis 75% 100%
A4I3F2 Leishmania infantum 89% 100%
Q4Q8J2 Leishmania major 90% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS