Aurora kinase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Aurora kinase

Gene product:

protein kinase, putative

Species:

Leishmania mexicana

UniProt:

E9AZL3_LEIMU

TriTrypDb:

LmxM.28.0520

Length:

301

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005813	centrosome	3	1
GO:0005815	microtubule organizing center	2	1
GO:0005874	microtubule	6	1
GO:0005875	microtubule associated complex	2	1
GO:0005876	spindle microtubule	7	1
GO:0031616	spindle pole centrosome	4	1
GO:0032133	chromosome passenger complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0051233	spindle midzone	2	1
GO:0099080	supramolecular complex	2	1
GO:0099081	supramolecular polymer	3	1
GO:0099512	supramolecular fiber	4	1
GO:0099513	polymeric cytoskeletal fiber	5	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AZL3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZL3

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	12
GO:0006793	phosphorus metabolic process	3	12
GO:0006796	phosphate-containing compound metabolic process	4	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0016310	phosphorylation	5	12
GO:0019538	protein metabolic process	3	12
GO:0036211	protein modification process	4	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043412	macromolecule modification	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0071704	organic substance metabolic process	2	12
GO:1901564	organonitrogen compound metabolic process	3	12
GO:0000226	microtubule cytoskeleton organization	3	1
GO:0006996	organelle organization	4	1
GO:0007010	cytoskeleton organization	5	1
GO:0007017	microtubule-based process	2	1
GO:0007051	spindle organization	3	1
GO:0007052	mitotic spindle organization	4	1
GO:0010564	regulation of cell cycle process	5	1
GO:0016043	cellular component organization	3	1
GO:0022402	cell cycle process	2	1
GO:0032465	regulation of cytokinesis	5	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051302	regulation of cell division	4	1
GO:0051726	regulation of cell cycle	4	1
GO:0065007	biological regulation	1	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:1902850	microtubule cytoskeleton organization involved in mitosis	4	1
GO:1903047	mitotic cell cycle process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0004672	protein kinase activity	3	12
GO:0004674	protein serine/threonine kinase activity	4	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016301	kinase activity	4	12
GO:0016740	transferase activity	2	12
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	12
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140096	catalytic activity, acting on a protein	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0035173	histone kinase activity	4	1
GO:0035174	obsolete histone serine kinase activity	5	1
GO:0106310	protein serine kinase activity	4	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	183	185	PF00675	0.293
CLV_NRD_NRD_1	50	52	PF00675	0.422
CLV_NRD_NRD_1	77	79	PF00675	0.302
CLV_PCSK_KEX2_1	183	185	PF00082	0.289
CLV_PCSK_KEX2_1	268	270	PF00082	0.318
CLV_PCSK_KEX2_1	297	299	PF00082	0.589
CLV_PCSK_KEX2_1	77	79	PF00082	0.302
CLV_PCSK_PC1ET2_1	268	270	PF00082	0.336
CLV_PCSK_PC1ET2_1	297	299	PF00082	0.589
CLV_PCSK_PC7_1	264	270	PF00082	0.318
CLV_PCSK_SKI1_1	153	157	PF00082	0.293
CLV_PCSK_SKI1_1	269	273	PF00082	0.318
CLV_PCSK_SKI1_1	89	93	PF00082	0.302
DEG_APCC_DBOX_1	268	276	PF00400	0.302
DEG_SCF_FBW7_1	222	229	PF00400	0.369
DOC_CKS1_1	16	21	PF01111	0.623
DOC_CYCLIN_RxL_1	86	94	PF00134	0.304
DOC_CYCLIN_yCln2_LP_2	276	282	PF00134	0.422
DOC_MAPK_gen_1	153	162	PF00069	0.300
DOC_MAPK_gen_1	51	59	PF00069	0.422
DOC_MAPK_gen_1	77	84	PF00069	0.302
DOC_MAPK_MEF2A_6	77	84	PF00069	0.302
DOC_MAPK_RevD_3	45	61	PF00069	0.387
DOC_PP2B_LxvP_1	125	128	PF13499	0.402
DOC_PP4_FxxP_1	126	129	PF00568	0.295
DOC_USP7_MATH_1	226	230	PF00917	0.338
DOC_USP7_MATH_2	195	201	PF00917	0.422
DOC_USP7_UBL2_3	61	65	PF12436	0.336
DOC_WW_Pin1_4	15	20	PF00397	0.626
DOC_WW_Pin1_4	187	192	PF00397	0.302
DOC_WW_Pin1_4	222	227	PF00397	0.302
DOC_WW_Pin1_4	289	294	PF00397	0.526
LIG_14-3-3_CanoR_1	183	193	PF00244	0.302
LIG_14-3-3_CterR_2	298	301	PF00244	0.730
LIG_Actin_RPEL_3	257	276	PF02755	0.449
LIG_deltaCOP1_diTrp_1	209	218	PF00928	0.302
LIG_deltaCOP1_diTrp_1	25	31	PF00928	0.428
LIG_FHA_1	223	229	PF00498	0.318
LIG_FHA_2	243	249	PF00498	0.365
LIG_FHA_2	25	31	PF00498	0.514
LIG_LIR_Apic_2	190	196	PF02991	0.302
LIG_LIR_Gen_1	103	110	PF02991	0.305
LIG_LIR_Gen_1	30	37	PF02991	0.305
LIG_LIR_Gen_1	69	76	PF02991	0.338
LIG_LIR_Gen_1	94	99	PF02991	0.336
LIG_LIR_Nem_3	103	108	PF02991	0.339
LIG_LIR_Nem_3	233	239	PF02991	0.360
LIG_LIR_Nem_3	30	34	PF02991	0.305
LIG_LIR_Nem_3	69	73	PF02991	0.338
LIG_LIR_Nem_3	94	98	PF02991	0.302
LIG_OCRL_FandH_1	83	95	PF00620	0.302
LIG_PTB_Apo_2	274	281	PF02174	0.247
LIG_SH2_CRK	236	240	PF00017	0.387
LIG_SH2_NCK_1	244	248	PF00017	0.359
LIG_SH2_STAP1	204	208	PF00017	0.302
LIG_SH2_STAP1	95	99	PF00017	0.359
LIG_SH2_STAT3	134	137	PF00017	0.302
LIG_SH2_STAT3	144	147	PF00017	0.302
LIG_SH2_STAT5	105	108	PF00017	0.118
LIG_SH2_STAT5	134	137	PF00017	0.345
LIG_SH2_STAT5	144	147	PF00017	0.288
LIG_SH2_STAT5	193	196	PF00017	0.288
LIG_SH2_STAT5	244	247	PF00017	0.359
LIG_SH2_STAT5	46	49	PF00017	0.318
LIG_SH2_STAT5	55	58	PF00017	0.318
LIG_SH2_STAT5	90	93	PF00017	0.302
LIG_SH2_STAT5	97	100	PF00017	0.302
LIG_SH3_3	16	22	PF00018	0.533
LIG_SH3_3	174	180	PF00018	0.302
MOD_CDK_SPK_2	18	23	PF00069	0.638
MOD_CK1_1	187	193	PF00069	0.288
MOD_CK1_1	21	27	PF00069	0.596
MOD_CK2_1	242	248	PF00069	0.235
MOD_Cter_Amidation	295	298	PF01082	0.563
MOD_GlcNHglycan	205	209	PF01048	0.294
MOD_GSK3_1	17	24	PF00069	0.635
MOD_GSK3_1	183	190	PF00069	0.302
MOD_GSK3_1	222	229	PF00069	0.369
MOD_GSK3_1	242	249	PF00069	0.297
MOD_GSK3_1	46	53	PF00069	0.384
MOD_NEK2_1	173	178	PF00069	0.295
MOD_NEK2_1	242	247	PF00069	0.372
MOD_NEK2_1	91	96	PF00069	0.302
MOD_NEK2_2	46	51	PF00069	0.318
MOD_PK_1	60	66	PF00069	0.318
MOD_PKA_1	183	189	PF00069	0.288
MOD_PKA_1	60	66	PF00069	0.318
MOD_PKA_2	183	189	PF00069	0.288
MOD_PKA_2	50	56	PF00069	0.422
MOD_Plk_1	24	30	PF00069	0.537
MOD_ProDKin_1	15	21	PF00069	0.622
MOD_ProDKin_1	187	193	PF00069	0.302
MOD_ProDKin_1	222	228	PF00069	0.302
MOD_ProDKin_1	289	295	PF00069	0.540
MOD_SUMO_for_1	155	158	PF00179	0.302
MOD_SUMO_for_1	22	25	PF00179	0.575
MOD_SUMO_rev_2	248	257	PF00179	0.318
TRG_DiLeu_BaEn_1	253	258	PF01217	0.318
TRG_ENDOCYTIC_2	105	108	PF00928	0.298
TRG_ENDOCYTIC_2	117	120	PF00928	0.298
TRG_ENDOCYTIC_2	236	239	PF00928	0.404
TRG_ENDOCYTIC_2	42	45	PF00928	0.302
TRG_ENDOCYTIC_2	95	98	PF00928	0.293
TRG_ER_diArg_1	76	78	PF00400	0.302
TRG_NES_CRM1_1	205	219	PF08389	0.422
TRG_NLS_MonoCore_2	296	301	PF00514	0.642
TRG_NLS_MonoExtN_4	294	301	PF00514	0.558
TRG_Pf-PMV_PEXEL_1	65	69	PF00026	0.336

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3N5	Leptomonas seymouri	27%	70%
A0A0N0P787	Leptomonas seymouri	27%	78%
A0A0N0P8H5	Leptomonas seymouri	36%	91%
A0A0N1HVN6	Leptomonas seymouri	28%	80%
A0A0N1HWQ2	Leptomonas seymouri	90%	100%
A0A0N1I2Z5	Leptomonas seymouri	29%	100%
A0A0N1I6T8	Leptomonas seymouri	33%	100%
A0A0N1I9B7	Leptomonas seymouri	27%	83%
A0A0N1IIF9	Leptomonas seymouri	32%	100%
A0A0N1PC31	Leptomonas seymouri	32%	77%
A0A0N1PD05	Leptomonas seymouri	27%	67%
A0A0N1PDW7	Leptomonas seymouri	30%	76%
A0A0S4IHW4	Bodo saltans	30%	67%
A0A0S4IMB7	Bodo saltans	26%	68%
A0A0S4IRU8	Bodo saltans	30%	70%
A0A0S4ISS4	Bodo saltans	33%	97%
A0A0S4IX86	Bodo saltans	28%	70%
A0A0S4IZY3	Bodo saltans	32%	90%
A0A0S4J3Y5	Bodo saltans	31%	70%
A0A0S4J444	Bodo saltans	24%	75%
A0A0S4J4B3	Bodo saltans	31%	67%
A0A0S4J4X4	Bodo saltans	28%	100%
A0A0S4J6L4	Bodo saltans	33%	79%
A0A0S4J9Q7	Bodo saltans	29%	66%
A0A0S4JA09	Bodo saltans	31%	73%
A0A0S4JBR3	Bodo saltans	70%	96%
A0A0S4JCG2	Bodo saltans	33%	67%
A0A0S4JER5	Bodo saltans	30%	66%
A0A0S4JF22	Bodo saltans	26%	84%
A0A0S4JMF5	Bodo saltans	29%	80%
A0A0S4JPZ1	Bodo saltans	28%	67%
A0A0S4JUJ2	Bodo saltans	35%	100%
A0A0S4JWD5	Bodo saltans	30%	77%
A0A0S4KFT7	Bodo saltans	35%	90%
A0A0S4KMV7	Bodo saltans	31%	93%
A0A0S4KN74	Bodo saltans	28%	92%
A0A1X0NIA0	Trypanosomatidae	26%	70%
A0A1X0NKA1	Trypanosomatidae	29%	68%
A0A1X0NQ63	Trypanosomatidae	32%	100%
A0A1X0NRZ9	Trypanosomatidae	28%	82%
A0A1X0NTR6	Trypanosomatidae	29%	86%
A0A1X0NUQ4	Trypanosomatidae	31%	79%
A0A1X0NW24	Trypanosomatidae	29%	86%
A0A1X0NY93	Trypanosomatidae	33%	77%
A0A1X0NYK8	Trypanosomatidae	84%	97%
A0A1X0P527	Trypanosomatidae	26%	68%
A0A1X0P5B1	Trypanosomatidae	33%	91%
A0A1X0P5F2	Trypanosomatidae	33%	91%
A0A1X0P6V1	Trypanosomatidae	32%	100%
A0A1X0P735	Trypanosomatidae	31%	100%
A0A1X0P7V0	Trypanosomatidae	35%	89%
A0A1X0P8F7	Trypanosomatidae	30%	69%
A0A1X0P919	Trypanosomatidae	29%	81%
A0A1X0PAW2	Trypanosomatidae	24%	85%
A0A3Q8IB30	Leishmania donovani	34%	91%
A0A3Q8IBT5	Leishmania donovani	27%	100%
A0A3Q8IEH3	Leishmania donovani	97%	100%
A0A3Q8IFK8	Leishmania donovani	27%	68%
A0A3Q8IFW0	Leishmania donovani	26%	70%
A0A3Q8IIG1	Leishmania donovani	26%	100%
A0A3Q8INQ4	Leishmania donovani	33%	77%
A0A3Q8INS5	Leishmania donovani	27%	100%
A0A3R7KCZ4	Trypanosoma rangeli	27%	75%
A0A3R7M5C7	Trypanosoma rangeli	34%	100%
A0A3R7MHW5	Trypanosoma rangeli	32%	75%
A0A3R7MSS9	Trypanosoma rangeli	28%	74%
A0A3R7N4D8	Trypanosoma rangeli	32%	75%
A0A3R7N5S4	Trypanosoma rangeli	31%	79%
A0A3R7RLL1	Trypanosoma rangeli	27%	70%
A0A3S5H606	Leishmania donovani	33%	100%
A0A3S5IRC3	Trypanosoma rangeli	27%	80%
A0A3S7WTN9	Leishmania donovani	27%	78%
A0A3S7WUX5	Leishmania donovani	31%	100%
A0A3S7WVE9	Leishmania donovani	28%	100%
A0A3S7WWE7	Leishmania donovani	27%	100%
A0A3S7X2W3	Leishmania donovani	28%	81%
A0A3S7X6T8	Leishmania donovani	27%	67%
A0A3S7X7Y2	Leishmania donovani	28%	78%
A0A3S7X9R4	Leishmania donovani	32%	81%
A0A3S7X9S2	Leishmania donovani	32%	89%
A0A422MYB4	Trypanosoma rangeli	33%	95%
A0A422N3Y6	Trypanosoma rangeli	30%	68%
A0A422N701	Trypanosoma rangeli	29%	67%
A0A422NJ30	Trypanosoma rangeli	31%	100%
A0A422P0J2	Trypanosoma rangeli	36%	89%
A0A422P0N6	Trypanosoma rangeli	27%	96%
A0A422P1R5	Trypanosoma rangeli	84%	97%
A0A422P270	Trypanosoma rangeli	32%	68%
A0A8I3S724	Canis lupus familiaris	45%	74%
A2ZAB5	Oryza sativa subsp. indica	30%	90%
A3B529	Oryza sativa subsp. japonica	34%	69%
A4H539	Leishmania braziliensis	34%	100%
A4H8C4	Leishmania braziliensis	27%	100%
A4H9H4	Leishmania braziliensis	31%	100%
A4H9L8	Leishmania braziliensis	34%	100%
A4H9X2	Leishmania braziliensis	27%	100%
A4HA94	Leishmania braziliensis	27%	100%
A4HAS1	Leishmania braziliensis	25%	100%
A4HBL4	Leishmania braziliensis	28%	100%
A4HED7	Leishmania braziliensis	33%	100%
A4HEL2	Leishmania braziliensis	26%	100%
A4HG26	Leishmania braziliensis	24%	100%
A4HG92	Leishmania braziliensis	96%	100%
A4HH03	Leishmania braziliensis	25%	100%
A4HHN1	Leishmania braziliensis	28%	100%
A4HHS9	Leishmania braziliensis	25%	100%
A4HJT5	Leishmania braziliensis	27%	68%
A4HJW2	Leishmania braziliensis	26%	70%
A4HLR0	Leishmania braziliensis	27%	67%
A4HN71	Leishmania braziliensis	33%	100%
A4HTB4	Leishmania infantum	33%	100%
A4HWP5	Leishmania infantum	27%	78%
A4HXU0	Leishmania infantum	31%	100%
A4HXY2	Leishmania infantum	34%	91%
A4HYH4	Leishmania infantum	26%	100%
A4HZA2	Leishmania infantum	27%	100%
A4I1T4	Leishmania infantum	33%	77%
A4I1U3	Leishmania infantum	27%	100%
A4I3C6	Leishmania infantum	97%	100%
A4I435	Leishmania infantum	26%	100%
A4I4U6	Leishmania infantum	28%	81%
A4I7A1	Leishmania infantum	27%	68%
A4I7C4	Leishmania infantum	26%	70%
A4I960	Leishmania infantum	27%	67%
A4I9Y5	Leishmania infantum	28%	78%
A4IBT4	Leishmania infantum	32%	79%
A4IBT9	Leishmania infantum	32%	81%
A4IGM9	Xenopus tropicalis	43%	84%
A5GFW1	Sus scrofa	45%	75%
A7MB74	Bos taurus	34%	70%
A8X6H4	Caenorhabditis briggsae	27%	85%
A8XJQ6	Caenorhabditis briggsae	31%	78%
A8XW88	Caenorhabditis briggsae	34%	80%
A9S5R3	Physcomitrium patens	31%	87%
C9ZKE1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	74%
C9ZL78	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	71%
C9ZMH9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	68%
C9ZS83	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
C9ZSI7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	98%
C9ZUK8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
C9ZWG7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	70%
C9ZWI1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	70%
C9ZXP1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	77%
C9ZYS7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	77%
C9ZYT4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	76%
C9ZZX0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
C9ZZX1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
D0A0D3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
D0A2R4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	80%
D0A5C6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	89%
D0A820	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	79%	94%
D7UQM5	Patiria pectinifera	45%	74%
E8NHK0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AFM1	Leishmania major	33%	100%
E9AGR7	Leishmania infantum	28%	100%
E9ALA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9ALF2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9ALJ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9AMP2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AQF3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9ARK2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9ARP5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	91%
E9ARW6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9AS98	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9AUY2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9AVR5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	81%
E9AXW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	77%
E9AXY7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9B0C2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B296	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	68%
E9B2B7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	70%
E9B436	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	67%
E9B4Z4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	78%
E9B6S4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	79%
E9B6S9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	81%
O00141	Homo sapiens	34%	70%
O01427	Caenorhabditis elegans	42%	99%
O14047	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	96%
O14965	Homo sapiens	43%	75%
O22932	Arabidopsis thaliana	31%	69%
O43930	Homo sapiens	33%	100%
O55099	Rattus norvegicus	44%	88%
O59790	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	85%
O64629	Arabidopsis thaliana	42%	100%
O65554	Arabidopsis thaliana	31%	68%
O70126	Mus musculus	44%	87%
O70150	Rattus norvegicus	29%	88%
O80902	Arabidopsis thaliana	32%	70%
O88445	Mus musculus	45%	100%
P00517	Bos taurus	32%	86%
P05131	Bos taurus	33%	86%
P05132	Mus musculus	32%	86%
P05383	Sus scrofa	33%	86%
P05986	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	76%
P06244	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	76%
P06245	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	79%
P0C5D6	Oryza sativa subsp. japonica	30%	90%
P12370	Drosophila melanogaster	33%	85%
P16911	Drosophila melanogaster	36%	85%
P17612	Homo sapiens	32%	86%
P21137	Caenorhabditis elegans	34%	75%
P21901	Aplysia californica	30%	86%
P22612	Homo sapiens	34%	86%
P22694	Homo sapiens	33%	86%
P25321	Cricetulus griseus	32%	86%
P25323	Dictyostelium discoideum	32%	100%
P27791	Rattus norvegicus	32%	86%
P36887	Sus scrofa	32%	86%
P38991	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	42%	82%
P43291	Arabidopsis thaliana	31%	83%
P43292	Arabidopsis thaliana	31%	85%
P49673	Ascaris suum	31%	89%
P51817	Homo sapiens	34%	84%
P54644	Dictyostelium discoideum	33%	68%
P59241	Rattus norvegicus	44%	76%
P68180	Cricetulus griseus	33%	86%
P68181	Mus musculus	33%	86%
P68182	Rattus norvegicus	33%	86%
P92937	Arabidopsis thaliana	32%	71%
P97477	Mus musculus	44%	76%
Q06226	Rattus norvegicus	34%	70%
Q10LQ2	Oryza sativa subsp. japonica	32%	67%
Q10SC8	Oryza sativa subsp. japonica	30%	66%
Q12706	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	69%
Q14012	Homo sapiens	29%	81%
Q27687	Leishmania major	34%	100%
Q2QMI0	Oryza sativa subsp. japonica	33%	66%
Q2QY53	Oryza sativa subsp. japonica	32%	69%
Q2QYM3	Oryza sativa subsp. japonica	30%	69%
Q2RAX3	Oryza sativa subsp. japonica	32%	66%
Q2RBF0	Oryza sativa subsp. japonica	30%	69%
Q2TA06	Bos taurus	44%	75%
Q2V452	Arabidopsis thaliana	31%	68%
Q4Q2Z2	Leishmania major	28%	100%
Q4Q3Y9	Leishmania major	28%	67%
Q4Q5T9	Leishmania major	26%	70%
Q4Q5W2	Leishmania major	27%	68%
Q4Q7W2	Leishmania major	27%	100%
Q4Q9I7	Leishmania major	27%	100%
Q4Q9K2	Leishmania major	33%	100%
Q4QCK0	Leishmania major	27%	100%
Q4QCR2	Leishmania major	27%	100%
Q4QD66	Leishmania major	26%	100%
Q4QDK6	Leishmania major	28%	100%
Q4QDX7	Leishmania major	31%	100%
Q4QF23	Leishmania major	27%	100%
Q4QHY3	Leishmania major	23%	100%
Q4QHY4	Leishmania major	23%	100%
Q4QIJ7	Leishmania major	33%	100%
Q4R633	Macaca fascicularis	34%	70%
Q54CY9	Dictyostelium discoideum	33%	96%
Q54SJ5	Dictyostelium discoideum	33%	96%
Q54UZ1	Dictyostelium discoideum	31%	73%
Q54WX4	Dictyostelium discoideum	46%	78%
Q5BKK4	Xenopus tropicalis	34%	72%
Q5JLD8	Oryza sativa subsp. japonica	32%	67%
Q5KQF5	Oryza sativa subsp. japonica	30%	67%
Q5Q0U5	Fundulus heteroclitus	35%	70%
Q5QN75	Oryza sativa subsp. japonica	29%	85%
Q61XD3	Caenorhabditis briggsae	41%	100%
Q63450	Rattus norvegicus	30%	80%
Q683C9	Arabidopsis thaliana	45%	100%
Q69Q47	Oryza sativa subsp. japonica	32%	66%
Q6A1A2	Homo sapiens	31%	76%
Q6BVA0	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	42%	73%
Q6C3J2	Yarrowia lipolytica (strain CLIB 122 / E 150)	45%	81%
Q6CWQ4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	41%	83%
Q6DE08	Xenopus laevis	42%	83%
Q6ERS0	Oryza sativa subsp. japonica	32%	75%
Q6ERS4	Oryza sativa subsp. japonica	33%	66%
Q6FV07	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	39%	84%
Q6GLY8	Xenopus laevis	34%	69%
Q6GPL3	Xenopus laevis	41%	82%
Q6GPN6	Xenopus laevis	34%	69%
Q6NW76	Danio rerio	41%	94%
Q6SA08	Homo sapiens	32%	92%
Q6U1I9	Gallus gallus	34%	70%
Q6X4A2	Oryza sativa subsp. japonica	32%	67%
Q6ZI44	Oryza sativa subsp. japonica	30%	82%
Q6ZLP5	Oryza sativa subsp. japonica	32%	67%
Q755C4	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	41%	82%
Q75GK4	Oryza sativa subsp. japonica	34%	67%
Q75H77	Oryza sativa subsp. japonica	31%	83%
Q75L42	Oryza sativa subsp. japonica	29%	66%
Q75V57	Oryza sativa subsp. japonica	30%	83%
Q7JP68	Caenorhabditis elegans	31%	76%
Q7X996	Oryza sativa subsp. japonica	32%	68%
Q7XIW5	Oryza sativa subsp. japonica	31%	68%
Q7XQP4	Oryza sativa subsp. japonica	30%	84%
Q7YRC6	Bos taurus	45%	88%
Q7ZTW4	Danio rerio	35%	70%
Q84VQ3	Arabidopsis thaliana	34%	69%
Q869W6	Dictyostelium discoideum	31%	86%
Q86AD7	Dictyostelium discoideum	33%	77%
Q8BW96	Mus musculus	27%	78%
Q8IU85	Homo sapiens	27%	78%
Q8LIG4	Oryza sativa subsp. japonica	32%	68%
Q8MJ44	Canis lupus familiaris	32%	86%
Q8MYF1	Dictyostelium discoideum	29%	66%
Q8R4U9	Rattus norvegicus	36%	82%
Q8SRK8	Encephalitozoon cuniculi (strain GB-M1)	34%	93%
Q8SRL5	Encephalitozoon cuniculi (strain GB-M1)	43%	100%
Q91819	Xenopus laevis	45%	74%
Q91820	Xenopus laevis	43%	74%
Q91YS8	Mus musculus	30%	80%
Q922R0	Mus musculus	32%	85%
Q940H6	Arabidopsis thaliana	31%	83%
Q94CG0	Arabidopsis thaliana	31%	72%
Q96GD4	Homo sapiens	45%	88%
Q96QS6	Homo sapiens	29%	78%
Q9D411	Mus musculus	33%	92%
Q9FFP9	Arabidopsis thaliana	31%	84%
Q9FJ54	Arabidopsis thaliana	32%	69%
Q9GNR4	Leishmania major	33%	100%
Q9HBY8	Homo sapiens	35%	82%
Q9LDI3	Arabidopsis thaliana	33%	67%
Q9LEU7	Arabidopsis thaliana	32%	68%
Q9LYQ8	Arabidopsis thaliana	32%	66%
Q9M077	Arabidopsis thaliana	45%	100%
Q9MAM1	Arabidopsis thaliana	30%	67%
Q9MZD9	Ovis aries	32%	86%
Q9N0X0	Sus scrofa	45%	88%
Q9N2N1	Leishmania major	98%	100%
Q9QYK9	Mus musculus	29%	88%
Q9QZS5	Mus musculus	36%	82%
Q9STV4	Arabidopsis thaliana	31%	68%
Q9SUL7	Arabidopsis thaliana	34%	71%
Q9TXJ0	Caenorhabditis elegans	27%	86%
Q9U6V4	Leishmania donovani	26%	100%
Q9UQB9	Homo sapiens	43%	97%
Q9VKN7	Drosophila melanogaster	44%	91%
Q9WVC6	Mus musculus	34%	70%
Q9XIW0	Arabidopsis thaliana	37%	70%
Q9XT18	Oryctolagus cuniculus	34%	70%
Q9Y077	Leishmania major	28%	100%
V5B871	Trypanosoma cruzi	29%	70%
V5BAZ8	Trypanosoma cruzi	32%	78%
V5BC61	Trypanosoma cruzi	36%	97%
V5BCH2	Trypanosoma cruzi	33%	77%
V5BEK5	Trypanosoma cruzi	35%	89%
V5BFI8	Trypanosoma cruzi	30%	68%
V5BG98	Trypanosoma cruzi	83%	97%
V5BNV8	Trypanosoma cruzi	33%	100%
V5BQF4	Trypanosoma cruzi	28%	81%
V5BQH6	Trypanosoma cruzi	34%	69%
V5BWC2	Trypanosoma cruzi	30%	100%
V5D579	Trypanosoma cruzi	29%	70%
V5DI55	Trypanosoma cruzi	31%	72%
V5DPP5	Trypanosoma cruzi	26%	70%
V5DUQ7	Trypanosoma cruzi	26%	80%
W0LYS5	Macrobrachium nipponense	29%	87%