Cauli_VI domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AZJ0_LEIMU

TriTrypDb:

LmxM.28.0290

Length:

252

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZJ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZJ0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	183	187	PF00656	0.480
CLV_C14_Caspase3-7	72	76	PF00656	0.602
CLV_NRD_NRD_1	164	166	PF00675	0.593
CLV_NRD_NRD_1	2	4	PF00675	0.629
CLV_NRD_NRD_1	212	214	PF00675	0.546
CLV_NRD_NRD_1	60	62	PF00675	0.425
CLV_PCSK_KEX2_1	138	140	PF00082	0.457
CLV_PCSK_KEX2_1	2	4	PF00082	0.629
CLV_PCSK_KEX2_1	60	62	PF00082	0.429
CLV_PCSK_PC1ET2_1	138	140	PF00082	0.457
CLV_PCSK_PC1ET2_1	2	4	PF00082	0.629
CLV_PCSK_SKI1_1	49	53	PF00082	0.592
CLV_PCSK_SKI1_1	61	65	PF00082	0.374
DEG_Kelch_actinfilin_1	168	172	PF01344	0.575
DEG_Nend_UBRbox_1	1	4	PF02207	0.631
DOC_CKS1_1	198	203	PF01111	0.419
DOC_CYCLIN_yCln2_LP_2	189	195	PF00134	0.317
DOC_MAPK_gen_1	165	172	PF00069	0.556
DOC_USP7_MATH_1	158	162	PF00917	0.515
DOC_USP7_MATH_1	181	185	PF00917	0.598
DOC_USP7_MATH_1	28	32	PF00917	0.442
DOC_USP7_MATH_1	42	46	PF00917	0.411
DOC_WW_Pin1_4	116	121	PF00397	0.525
DOC_WW_Pin1_4	144	149	PF00397	0.562
DOC_WW_Pin1_4	174	179	PF00397	0.612
DOC_WW_Pin1_4	197	202	PF00397	0.347
LIG_APCC_ABBA_1	109	114	PF00400	0.424
LIG_BIR_III_2	117	121	PF00653	0.575
LIG_CtBP_PxDLS_1	21	25	PF00389	0.409
LIG_eIF4E_1	198	204	PF01652	0.386
LIG_FHA_1	198	204	PF00498	0.386
LIG_FHA_1	227	233	PF00498	0.566
LIG_FHA_1	32	38	PF00498	0.373
LIG_FHA_1	76	82	PF00498	0.496
LIG_FHA_1	94	100	PF00498	0.508
LIG_FHA_2	111	117	PF00498	0.433
LIG_FHA_2	28	34	PF00498	0.482
LIG_FHA_2	70	76	PF00498	0.585
LIG_LIR_Nem_3	188	194	PF02991	0.352
LIG_LIR_Nem_3	238	244	PF02991	0.445
LIG_LYPXL_S_1	190	194	PF13949	0.340
LIG_LYPXL_yS_3	191	194	PF13949	0.338
LIG_SH3_1	4	10	PF00018	0.541
LIG_SH3_3	152	158	PF00018	0.670
LIG_SH3_3	167	173	PF00018	0.589
LIG_SH3_3	175	181	PF00018	0.463
LIG_SH3_3	191	197	PF00018	0.326
LIG_SH3_3	4	10	PF00018	0.725
LIG_SUMO_SIM_anti_2	80	85	PF11976	0.549
LIG_TYR_ITIM	189	194	PF00017	0.262
MOD_CDC14_SPxK_1	147	150	PF00782	0.597
MOD_CDK_SPxK_1	144	150	PF00069	0.567
MOD_CK1_1	31	37	PF00069	0.381
MOD_CK1_1	71	77	PF00069	0.717
MOD_CK1_1	93	99	PF00069	0.496
MOD_CK2_1	116	122	PF00069	0.550
MOD_CK2_1	27	33	PF00069	0.598
MOD_CK2_1	63	69	PF00069	0.476
MOD_GlcNHglycan	183	186	PF01048	0.409
MOD_GlcNHglycan	235	238	PF01048	0.470
MOD_GlcNHglycan	30	33	PF01048	0.464
MOD_GlcNHglycan	44	47	PF01048	0.413
MOD_GlcNHglycan	56	59	PF01048	0.292
MOD_GSK3_1	153	160	PF00069	0.558
MOD_GSK3_1	181	188	PF00069	0.608
MOD_GSK3_1	226	233	PF00069	0.461
MOD_GSK3_1	27	34	PF00069	0.441
MOD_GSK3_1	71	78	PF00069	0.669
MOD_GSK3_1	86	93	PF00069	0.512
MOD_GSK3_1	95	102	PF00069	0.475
MOD_PKA_1	2	8	PF00069	0.552
MOD_PKA_2	2	8	PF00069	0.552
MOD_PKA_2	93	99	PF00069	0.496
MOD_Plk_1	68	74	PF00069	0.675
MOD_Plk_1	79	85	PF00069	0.536
MOD_Plk_2-3	69	75	PF00069	0.581
MOD_Plk_4	102	108	PF00069	0.545
MOD_Plk_4	127	133	PF00069	0.466
MOD_Plk_4	185	191	PF00069	0.317
MOD_Plk_4	244	250	PF00069	0.473
MOD_Plk_4	31	37	PF00069	0.381
MOD_Plk_4	95	101	PF00069	0.545
MOD_ProDKin_1	116	122	PF00069	0.528
MOD_ProDKin_1	144	150	PF00069	0.567
MOD_ProDKin_1	174	180	PF00069	0.604
MOD_ProDKin_1	197	203	PF00069	0.343
MOD_SUMO_rev_2	160	168	PF00179	0.594
TRG_DiLeu_BaEn_1	22	27	PF01217	0.390
TRG_DiLeu_BaLyEn_6	239	244	PF01217	0.465
TRG_ENDOCYTIC_2	191	194	PF00928	0.341
TRG_ER_diArg_1	59	61	PF00400	0.411
TRG_NLS_MonoExtC_3	212	218	PF00514	0.442
TRG_Pf-PMV_PEXEL_1	49	53	PF00026	0.490

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7G9	Leptomonas seymouri	47%	96%
A0A3S7X157	Leishmania donovani	88%	100%
A4HG70	Leishmania braziliensis	77%	100%
A4I3B3	Leishmania infantum	88%	100%
Q4Q8P1	Leishmania major	86%	100%