LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

EF-hand domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
EF-hand domain-containing protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9AZI4_LEIMU
TriTrypDb:
LmxM.28.0230
Length:
328

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AZI4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZI4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 250 252 PF00675 0.691
CLV_PCSK_KEX2_1 249 251 PF00082 0.651
CLV_PCSK_KEX2_1 301 303 PF00082 0.584
CLV_PCSK_PC1ET2_1 301 303 PF00082 0.584
CLV_Separin_Metazoa 246 250 PF03568 0.532
DOC_CKS1_1 15 20 PF01111 0.677
DOC_USP7_MATH_1 174 178 PF00917 0.645
DOC_WW_Pin1_4 100 105 PF00397 0.674
DOC_WW_Pin1_4 137 142 PF00397 0.685
DOC_WW_Pin1_4 14 19 PF00397 0.770
DOC_WW_Pin1_4 145 150 PF00397 0.558
DOC_WW_Pin1_4 28 33 PF00397 0.651
DOC_WW_Pin1_4 283 288 PF00397 0.507
DOC_WW_Pin1_4 92 97 PF00397 0.643
LIG_14-3-3_CanoR_1 153 160 PF00244 0.648
LIG_14-3-3_CanoR_1 175 183 PF00244 0.651
LIG_14-3-3_CanoR_1 215 220 PF00244 0.697
LIG_14-3-3_CanoR_1 69 79 PF00244 0.729
LIG_BIR_II_1 1 5 PF00653 0.673
LIG_BRCT_BRCA1_1 309 313 PF00533 0.642
LIG_FHA_1 101 107 PF00498 0.605
LIG_FHA_1 153 159 PF00498 0.750
LIG_FHA_1 171 177 PF00498 0.575
LIG_FHA_1 216 222 PF00498 0.788
LIG_FHA_1 243 249 PF00498 0.672
LIG_FHA_1 29 35 PF00498 0.722
LIG_FHA_1 41 47 PF00498 0.677
LIG_FHA_1 56 62 PF00498 0.686
LIG_FHA_2 45 51 PF00498 0.609
LIG_FHA_2 6 12 PF00498 0.685
LIG_FXI_DFP_1 321 325 PF00024 0.598
LIG_LIR_Gen_1 76 84 PF02991 0.763
LIG_LIR_Nem_3 291 296 PF02991 0.637
LIG_LIR_Nem_3 76 81 PF02991 0.761
LIG_NRBOX 126 132 PF00104 0.540
LIG_PDZ_Class_2 323 328 PF00595 0.653
LIG_Pex14_2 276 280 PF04695 0.469
LIG_Pex14_2 320 324 PF04695 0.650
LIG_SH2_NCK_1 94 98 PF00017 0.510
LIG_SH2_STAT5 94 97 PF00017 0.516
LIG_SH3_3 105 111 PF00018 0.681
LIG_SH3_3 136 142 PF00018 0.738
LIG_SH3_3 293 299 PF00018 0.513
LIG_SUMO_SIM_par_1 123 132 PF11976 0.533
LIG_SUMO_SIM_par_1 224 232 PF11976 0.681
LIG_TRAF2_1 133 136 PF00917 0.724
LIG_TRAF2_1 143 146 PF00917 0.588
LIG_TRAF2_1 154 157 PF00917 0.604
LIG_TRAF2_1 268 271 PF00917 0.631
LIG_TRAF2_2 165 170 PF00917 0.510
MOD_CDK_SPxxK_3 14 21 PF00069 0.754
MOD_CDK_SPxxK_3 28 35 PF00069 0.600
MOD_CK1_1 193 199 PF00069 0.713
MOD_CK1_1 225 231 PF00069 0.693
MOD_CK1_1 286 292 PF00069 0.501
MOD_CK1_1 71 77 PF00069 0.782
MOD_CK2_1 126 132 PF00069 0.603
MOD_CK2_1 174 180 PF00069 0.640
MOD_CK2_1 225 231 PF00069 0.693
MOD_CK2_1 33 39 PF00069 0.586
MOD_CK2_1 44 50 PF00069 0.615
MOD_CK2_1 5 11 PF00069 0.705
MOD_CK2_1 70 76 PF00069 0.622
MOD_CK2_1 87 93 PF00069 0.524
MOD_GlcNHglycan 159 163 PF01048 0.711
MOD_GlcNHglycan 288 291 PF01048 0.702
MOD_GlcNHglycan 73 76 PF01048 0.792
MOD_GSK3_1 10 17 PF00069 0.700
MOD_GSK3_1 170 177 PF00069 0.603
MOD_GSK3_1 189 196 PF00069 0.628
MOD_GSK3_1 225 232 PF00069 0.675
MOD_GSK3_1 33 40 PF00069 0.594
MOD_GSK3_1 70 77 PF00069 0.719
MOD_N-GLC_1 55 60 PF02516 0.723
MOD_N-GLC_2 98 100 PF02516 0.504
MOD_NEK2_1 213 218 PF00069 0.568
MOD_NEK2_1 307 312 PF00069 0.636
MOD_NEK2_1 70 75 PF00069 0.666
MOD_PIKK_1 147 153 PF00454 0.698
MOD_PIKK_1 213 219 PF00454 0.604
MOD_PIKK_1 68 74 PF00454 0.670
MOD_PKA_2 152 158 PF00069 0.653
MOD_PKA_2 174 180 PF00069 0.651
MOD_PKA_2 68 74 PF00069 0.735
MOD_PKB_1 35 43 PF00069 0.676
MOD_Plk_1 10 16 PF00069 0.655
MOD_Plk_1 158 164 PF00069 0.746
MOD_Plk_1 37 43 PF00069 0.727
MOD_Plk_4 10 16 PF00069 0.662
MOD_Plk_4 126 132 PF00069 0.555
MOD_Plk_4 190 196 PF00069 0.663
MOD_Plk_4 204 210 PF00069 0.529
MOD_Plk_4 222 228 PF00069 0.676
MOD_Plk_4 37 43 PF00069 0.690
MOD_Plk_4 74 80 PF00069 0.723
MOD_ProDKin_1 100 106 PF00069 0.674
MOD_ProDKin_1 137 143 PF00069 0.685
MOD_ProDKin_1 14 20 PF00069 0.769
MOD_ProDKin_1 145 151 PF00069 0.557
MOD_ProDKin_1 28 34 PF00069 0.651
MOD_ProDKin_1 283 289 PF00069 0.508
MOD_ProDKin_1 92 98 PF00069 0.642
MOD_SUMO_rev_2 80 90 PF00179 0.524
TRG_DiLeu_BaEn_1 123 128 PF01217 0.527
TRG_DiLeu_BaEn_1 159 164 PF01217 0.662
TRG_ENDOCYTIC_2 210 213 PF00928 0.572
TRG_ER_diArg_1 248 251 PF00400 0.751
TRG_ER_diArg_1 34 37 PF00400 0.647
TRG_Pf-PMV_PEXEL_1 251 255 PF00026 0.646

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IHW6 Leishmania donovani 87% 100%
A4HG64 Leishmania braziliensis 53% 100%
A4I396 Leishmania infantum 87% 100%
Q4Q8P7 Leishmania major 84% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS