Ribosome biogenesis protein SLX9

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AZF9_LEIMU

TriTrypDb:

LmxM.27.2500

Length:

137

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AZF9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZF9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	19	23	PF00656	0.809
CLV_NRD_NRD_1	134	136	PF00675	0.661
CLV_NRD_NRD_1	61	63	PF00675	0.611
CLV_NRD_NRD_1	86	88	PF00675	0.581
CLV_NRD_NRD_1	99	101	PF00675	0.635
CLV_PCSK_FUR_1	106	110	PF00082	0.756
CLV_PCSK_KEX2_1	108	110	PF00082	0.656
CLV_PCSK_KEX2_1	134	136	PF00082	0.619
CLV_PCSK_KEX2_1	4	6	PF00082	0.687
CLV_PCSK_KEX2_1	61	63	PF00082	0.605
CLV_PCSK_KEX2_1	9	11	PF00082	0.715
CLV_PCSK_KEX2_1	99	101	PF00082	0.635
CLV_PCSK_PC1ET2_1	108	110	PF00082	0.656
CLV_PCSK_PC1ET2_1	4	6	PF00082	0.687
CLV_PCSK_PC1ET2_1	9	11	PF00082	0.715
CLV_PCSK_PC7_1	5	11	PF00082	0.654
CLV_PCSK_SKI1_1	101	105	PF00082	0.650
CLV_PCSK_SKI1_1	5	9	PF00082	0.481
CLV_PCSK_SKI1_1	62	66	PF00082	0.579
CLV_PCSK_SKI1_1	91	95	PF00082	0.589
DEG_APCC_DBOX_1	86	94	PF00400	0.609
DEG_SPOP_SBC_1	23	27	PF00917	0.771
DOC_CKS1_1	28	33	PF01111	0.509
DOC_CYCLIN_yCln2_LP_2	8	14	PF00134	0.493
DOC_MAPK_gen_1	61	71	PF00069	0.615
DOC_MAPK_gen_1	84	92	PF00069	0.683
DOC_MAPK_MEF2A_6	62	71	PF00069	0.610
DOC_USP7_MATH_1	34	38	PF00917	0.658
DOC_USP7_UBL2_3	104	108	PF12436	0.666
DOC_WW_Pin1_4	27	32	PF00397	0.727
LIG_FHA_1	1	7	PF00498	0.659
LIG_FHA_1	81	87	PF00498	0.627
LIG_FHA_2	43	49	PF00498	0.599
LIG_Pex14_2	123	127	PF04695	0.743
LIG_SUMO_SIM_par_1	67	74	PF11976	0.608
LIG_TRAF2_1	79	82	PF00917	0.639
MOD_CK2_1	42	48	PF00069	0.493
MOD_Cter_Amidation	132	135	PF01082	0.694
MOD_GlcNHglycan	36	39	PF01048	0.759
MOD_GSK3_1	23	30	PF00069	0.730
MOD_GSK3_1	34	41	PF00069	0.678
MOD_NEK2_1	42	47	PF00069	0.561
MOD_PIKK_1	24	30	PF00454	0.664
MOD_PKB_1	78	86	PF00069	0.682
MOD_ProDKin_1	27	33	PF00069	0.727
TRG_DiLeu_BaEn_4	81	87	PF01217	0.631
TRG_ER_diArg_1	134	136	PF00400	0.703
TRG_NLS_MonoExtC_3	130	135	PF00514	0.639
TRG_NLS_MonoExtC_3	61	66	PF00514	0.664
TRG_NLS_MonoExtN_4	128	135	PF00514	0.630
TRG_NLS_MonoExtN_4	61	66	PF00514	0.664

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDY2	Leptomonas seymouri	66%	100%
A0A3Q8IQ83	Leishmania donovani	93%	100%
A4I332	Leishmania infantum	92%	100%
C9ZJM3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	100%
E9ACX0	Leishmania major	92%	100%