LeishMANIAdb
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MORN repeat family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
MORN repeat family protein
Gene product:
MORN repeat, putative
Species:
Leishmania mexicana
UniProt:
E9AZD7_LEIMU
TriTrypDb:
LmxM.27.2305
Length:
182

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 13
NetGPI no yes: 0, no: 13
Cellular components
Term Name Level Count
GO:0005930 axoneme 2 1
GO:0097542 ciliary tip 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9AZD7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AZD7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 4 6 PF00675 0.593
CLV_PCSK_KEX2_1 162 164 PF00082 0.420
CLV_PCSK_KEX2_1 4 6 PF00082 0.611
CLV_PCSK_PC1ET2_1 162 164 PF00082 0.420
CLV_PCSK_PC1ET2_1 4 6 PF00082 0.598
CLV_PCSK_SKI1_1 55 59 PF00082 0.436
DEG_SPOP_SBC_1 68 72 PF00917 0.684
DEG_SPOP_SBC_1 88 92 PF00917 0.229
DOC_MAPK_FxFP_2 17 20 PF00069 0.356
DOC_PP2B_LxvP_1 110 113 PF13499 0.391
DOC_PP4_FxxP_1 17 20 PF00568 0.356
DOC_USP7_MATH_1 136 140 PF00917 0.261
DOC_USP7_MATH_1 20 24 PF00917 0.366
DOC_USP7_MATH_1 69 73 PF00917 0.649
DOC_USP7_MATH_1 88 92 PF00917 0.487
DOC_USP7_UBL2_3 28 32 PF12436 0.519
LIG_APCC_ABBA_1 153 158 PF00400 0.391
LIG_FHA_1 117 123 PF00498 0.189
LIG_LIR_Apic_2 15 20 PF02991 0.292
LIG_PDZ_Class_2 177 182 PF00595 0.457
LIG_Pex14_1 164 168 PF04695 0.403
LIG_SH2_CRK 84 88 PF00017 0.482
LIG_SH2_STAT5 118 121 PF00017 0.280
LIG_SH2_STAT5 156 159 PF00017 0.257
LIG_SUMO_SIM_par_1 108 114 PF11976 0.269
MOD_CK1_1 111 117 PF00069 0.286
MOD_CK1_1 41 47 PF00069 0.694
MOD_CK1_1 48 54 PF00069 0.704
MOD_CK2_1 136 142 PF00069 0.261
MOD_CK2_1 20 26 PF00069 0.377
MOD_Cter_Amidation 160 163 PF01082 0.321
MOD_GlcNHglycan 113 116 PF01048 0.321
MOD_GlcNHglycan 40 43 PF01048 0.620
MOD_GlcNHglycan 71 74 PF01048 0.648
MOD_GlcNHglycan 91 94 PF01048 0.305
MOD_GSK3_1 40 47 PF00069 0.629
MOD_GSK3_1 64 71 PF00069 0.739
MOD_NEK2_1 127 132 PF00069 0.251
MOD_NEK2_1 13 18 PF00069 0.431
MOD_NEK2_1 87 92 PF00069 0.491
MOD_NEK2_2 20 25 PF00069 0.356
MOD_PKA_2 116 122 PF00069 0.286
MOD_Plk_4 136 142 PF00069 0.317
MOD_Plk_4 20 26 PF00069 0.378
MOD_SUMO_for_1 178 181 PF00179 0.476
TRG_ENDOCYTIC_2 84 87 PF00928 0.457

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IB90 Leptomonas seymouri 61% 100%
A0A0S4KPG9 Bodo saltans 30% 92%
A0A1X0NSQ0 Trypanosomatidae 39% 100%
A0A3Q8IQ71 Leishmania donovani 93% 100%
A0A3S5H6F3 Leishmania donovani 33% 82%
A0A422NAN4 Trypanosoma rangeli 38% 100%
A4HUC7 Leishmania infantum 32% 82%
A4I327 Leishmania infantum 93% 100%
C9ZJK1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 37% 100%
E9ACU8 Leishmania major 92% 100%
E9AI39 Leishmania braziliensis 34% 85%
Q6VTH5 Cyprinus carpio 30% 83%
V5BCY8 Trypanosoma cruzi 37% 100%
V5BX28 Trypanosoma cruzi 28% 71%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS